scholarly journals Role of Salivary MicroRNA and Cytokines in the Diagnosis and Prognosis of Oral Squamous Cell Carcinoma

2021 ◽  
Vol 22 (22) ◽  
pp. 12215
Author(s):  
Francisco Javier Manzano-Moreno ◽  
Victor J. Costela-Ruiz ◽  
Enrique García-Recio ◽  
Maria Victoria Olmedo-Gaya ◽  
Concepción Ruiz ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Early Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Positive Impact ◽  
Human Saliva ◽  
Rna Molecules ◽  
Proteomic Data ◽  
Dna And Rna

Oral squamous cell carcinoma (OSCC) is the most prevalent oral malignant tumor worldwide. An early diagnosis can have a major positive impact on its prognosis. Human saliva contains cytokines, DNA and RNA molecules, circulating cells, and derivatives of tissues and extracellular vesicles, among other factors that can serve as biomarkers. Hence, the analysis of saliva may provide useful information for the early diagnosis of OSCC for its prognosis. The objective of this review was to determine the potential usefulness of salivary biomarkers (cytokines and microRNA) to diagnose OSCC and improve its prognosis. A combination of salivary miRNA and proteomic data could allow a definitive and early diagnosis to be obtained. However, there remains a need to optimize and standardize the protocols used to quantify miRNAs.

Peptide functionalized upconversion/NIR II luminescent nanoparticles for targeted imaging and therapy of oral squamous cell carcinoma

2021 ◽  
Author(s):  
Bi Lin ◽  
Jun Wu ◽  
Yanxing Wang ◽  
Song Sun ◽  
Ying Yuan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Early Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Poor Prognosis ◽  
Targeted Imaging ◽  
Invasion And Metastasis ◽  
High Incidence ◽  
Luminescent Nanoparticles

Early diagnosis is critical and challenging for tongue squamous cell carcinoma (TSCC), which is a kind of tumor with high malignancy, poor prognosis, and a high incidence of invasion and metastasis.

EARLY DIAGNOSIS AND MULTIPLE FACES OF ORAL SQUAMOUS CELL CARCINOMA

2020 ◽  
Vol 129 (1) ◽  
pp. e85
Author(s):  
BRUNA FERNANDES DO CARMO CARVALHO ◽  
VICTOR COSTA ◽  
CESAR AUGUSTO CARDOSO ◽  
ANA LIA ANBINDER ◽  
ESTELA KAMINAGAKURA ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Early Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell

scholarly journals Spectrophotometry of Saliva of Oral Squamous CellCarcinoma Patients

2009 ◽  
Vol 6 (2) ◽  
pp. 373-378
Author(s):  
Baghdad Science Journal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Ir Spectrum ◽  
Human Saliva ◽  
Test Tube ◽  
Non Invasive ◽  
Back Ground

Back ground: Spectral analyses of solutions have long been applied to various body fluids for the purpose of clinical study as well as research .Human saliva can be easily obtained by non invasive .In this study typical spectra (for UV and IR) of saliva of oral cancer Squamous cell carcinoma patients were determined under average conditions and evaluated in relation to the spectra of normal specimens. Materials and Methods: Seventeen patients of oral cancer Squamous cell carcinoma and seventeen age matched healthy subject were included in this study .Chewing - Stimulated Saliva was collected in plastic test tube and stored at -20° C. Bach of saliva samples were used for UV and IR measurements. Results: Many differences between the IR spectrum of saliva of oral Squamous cell carcinoma patients and IR spectrum of normal saliva. Conclusion: The results in this study were detected that the use of IR spectroscopy may be useful in the diagnosis of oral Squamous cell carcinoma by using saliva samples.

scholarly journals Non-invasive early diagnosis of oral squamous cell carcinoma using piezoelectric biosensor

2020 ◽  
Vol 5 (3) ◽  
pp. 146
Author(s):  
Irene E. Rieuwpassa ◽  
Sumintarti Sumintarti ◽  
Yu-Ri Kim ◽  
Megatriani Matandung ◽  
Gabriel SA. Matongan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Early Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Non Invasive
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