scholarly journals Risk Factors of Patient-Related Safety Events during Active Mobilization for Intubated Patients in Intensive Care Units—A Multi-Center Retrospective Observational Study

2021 ◽  
Vol 10 (12) ◽  
pp. 2607
Author(s):  
Hajime Katsukawa ◽  
Kohei Ota ◽  
Keibun Liu ◽  
Yasunari Morita ◽  
Shinichi Watanabe ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Regression Analysis ◽  
Observational Study ◽  
Standing Position ◽  
Activity Level ◽  
Retrospective Observational Study ◽  
Tube Removal ◽  
Active Mobilization ◽  
Circulatory Dynamics

The aim of this study is to clarify the incidence and risk factors of patient-related safety events (PSE) in situations limited to intubated patients in which active mobilization, such as sitting on the edge of the bed/standing/walking, was carried out. A multi-center retrospective observational study was conducted at nine hospitals between January 2017 and March 2018. The safety profiles and PSE of 87 patients were analyzed. PSE occurred in 10 out of 87 patients (11.5%) and 13 out of 198 sessions (6.6%). The types of PSE that occurred were hypotension (8, 62%), heart rate instability (3, 23%), and desaturation (2, 15%). Circulation-related events occurred in 85% of overall cases. No accidents, such as line/tube removal or falls, were observed. The highest incidence of PSE was observed during the mobilization level of standing (8 out of 39 sessions, 20.5%). The occurrence of PSE correlated with the highest activity level under logistic regression analysis. Close vigilance is required for intubated patients during active mobilization in the standing position with regard to circulatory dynamics.

scholarly journals Evaluation of pre-slaughter losses of Italian heavy pigs

2017 ◽  
Vol 57 (10) ◽  
pp. 2072 ◽  
Author(s):  
Eleonora Nannoni ◽  
Gaetano Liuzzo ◽  
Andrea Serraino ◽  
Federica Giacometti ◽  
Giovanna Martelli ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Observational Study ◽  
Economic Impact ◽  
Logistic Regression Analysis ◽  
Stocking Density ◽  
Retrospective Observational Study

A retrospective observational study evaluated the risk factors for pre-slaughter losses (i.e. animal deaths occurring during transport and lairage) and their economic impact in Italian heavy pigs (~160 kg bodyweight). Of the 3 344 730 pigs transported, 1780 (0.053%) died before slaughter, with most losses occurring during transport (56.6%). The estimated economic impact was of 424 000 €. The percentage of batches with at least one animal lost pre-slaughter increased during summer (P < 0.001). The proportion of pre-slaughter losses was higher when journey lasted more than 90 min (P < 0.001) and was positively correlated with transport duration (P < 0.01). Losses were higher (P < 0.01) in batches transported at low stocking densities (i.e. when heavier pigs were transported). Batches with lower slaughtering order (i.e. longer lairage time) had higher proportions of losses (P < 0.001). Logistic regression analysis showed that the odds of a given batch to have at least one animal lost pre-slaughter were 1.32 times higher for batches slaughtered in summer, 1.54 times higher if journey durations exceeded 90 min, 1.25 times higher for batches with low slaughtering order, and not significantly influenced by stocking density during transport.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

Risk Factors for Encapsulating Peritoneal Sclerosis in Long-Term Peritoneal Dialysis: A Retrospective Observational Study

2013 ◽  
Vol 18 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Masatsugu Nakao ◽  
Keitaro Yokoyama ◽  
Izumi Yamamoto ◽  
Nanae Matsuo ◽  
Yudo Tanno ◽  
...  
Keyword(s):  
Risk Factors ◽  
Peritoneal Dialysis ◽  
Observational Study ◽  
Retrospective Observational Study

scholarly journals Bovine Tuberculosis (Mycobacterium bovis) Outbreak Duration in Cattle Herds in Ireland: A Retrospective Observational Study

Pathogens ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 815
Author(s):  
Andrew W. Byrne ◽  
Damien Barrett ◽  
Philip Breslin ◽  
Jamie M. Madden ◽  
James O'Keeffe ◽  
...  
Keyword(s):  
Risk Factors ◽  
Observational Study ◽  
Mycobacterium Bovis ◽  
Bovine Tuberculosis ◽  
Animal Health ◽  
Herd Size ◽  
Policy Formation ◽  
Nitrogen Loading ◽  
Management Policy ◽  
Retrospective Observational Study

Bovine tuberculosis (bTB) outbreaks, caused by Mycobacterium bovis infection, are a costly animal health challenge. Understanding factors associated with the duration of outbreaks, known as breakdowns, could lead to better disease management policy development. We undertook a retrospective observational study (2012–2018) and employed Finite Mixture Models (FMM) to model the outcome parameter, and to investigate how factors were associated with duration for differing subpopulations identified. In addition to traditional risk factors (e.g., herd size, bTB history), we also explored farm geographic area, parcels/farm fragmentation, metrics of intensity via nitrogen loading, and whether herds were designated controlled beef finishing units (CBFU) as potential risk factors for increased duration. The final model fitted log-normal distributions, with two latent classes (k) which partitioned the population into a subpopulation around the central tendency of the distribution, and a second around the tails of the distribution. The latter subpopulation included longer breakdowns of policy interest. Increasing duration was positively associated with recent (<3 years) TB history and the number of reactors disclosed, (log) herd size, beef herd-type relative to other herd types, number of land parcels, area, being designated a CBFU (“feedlot”) and having high annual inward cattle movements within the “tails” subpopulation. Breakdown length was negatively associated with the year of commencement of breakdown (i.e., a decreasing trend) and non-significantly with the organic nitrogen produced on the farm (N kg/hectare), a measure of stocking density. The latter finding may be due to confounding effects with herd size and area. Most variables contributed only moderately to explaining variation in breakdown duration, that is, they had moderate size effects on duration. Herd-size and CBFU had greater effect sizes on the outcome. The findings contribute to evidence-based policy formation in Ireland.

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