scholarly journals Quality of Life and Female Sexual Dysfunction in Croatian Women with Stress-, Urgency- and Mixed Urinary Incontinence: Results of a Cross-Sectional Study

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 240
Author(s):  
Ivan Radoja ◽  
Dunja Degmečić

Background and objectives: Urinary incontinence is defined as the involuntary leakage of urine. Studies have reported that the severity of urinary incontinence symptoms can cause decreased quality of life and female sexual dysfunction in women, but the association between the duration of the incontinence and the aforementioned disturbances has not been evaluated. The objective of this study was to evaluate the differences in the occurrence of decreased quality of life and female sexual dysfunction in Croatian women with urinary incontinence, with regard to the duration and subtype of urinary incontinence. Materials and Methods: We conducted a cross-sectional study from March 2017 to July 2018 at our neurourology and urodynamics outpatient clinic, among 120 women with urinary incontinence symptoms. Based on medical history, physical exam and urodynamic assessment, participants were divided into groups with stress-, urgency- and mixed urinary incontinence. Several quality of life and female sexual dysfunction questionnaires were used for evaluation. The differences between the three UI groups were tested by the Kruskal–Wallis test. All p values were two-sided. The level of significance was set to Alpha = 0.05. Results: The mixed urinary incontinence group had a significantly inferior quality of life (p = 0.003) and lower scores on the female sexual dysfunction questionnaires (p = 0.02). The longer the duration of incontinence King’s Health Questionnaire total score was worse (p = 0.003) and Female Sexual Function Index total score was worse (p < 0.001). Conclusions: Our results showed that there was a statistically significant difference in the occurrence of decreased quality of life and female sexual dysfunction considering the duration and subtype of incontinence in Croatian women.

2020 ◽  
Author(s):  
Diana-Leh-Ching Ng ◽  
Natasya Marliana Bt Abdul Malik ◽  
Chee-Shee Chai ◽  
Greta-Miranda-Kim-Choo Goh ◽  
Seng-Beng Tan ◽  
...  

Abstract Background:The use of warfarin in patients with non-valvular atrial fibrillation (NVAF) can be challenging. In this study, we evaluate the time in therapeutic range (TTR), health-related quality of life (HRQoL) and treatment satisfaction of patients on long-term warfarin for NVAF. The HRQoL and treatment satisfaction were compared based on the TTR.Methods:A cross-sectional study was conducted among patients on warfarin for NVAF who attended the anticoagulant clinic of a tertiary cardiology referral center in Sarawak from 1st June 2018 to 31st May 2019. Patients’ TTR was calculated by using Rosendaal technique, while their HRQoL and treatment satisfaction were assessed by using Short Form 12 Health Survey version 2 (SF12v2) and Duke Anticoagulant Satisfaction Scale (DASS), respectively. Results: A total of 300 patients were included, with mean TTR score of 47.0 ± 17.3%. The physical component summary (PCS) and mental component summary (MCS) score of SF-12v2 were 47.0 ± 9.0 and 53.5 ± 9.6, respectively. The total score for DASS was 55.2 ± 21.3, while the score for limitations (L), hassles and burdens (H&B) and positive psychological impacts (PPI) were 18.0 ± 10.0, 15.6 ± 9.1 and 21.6 ± 5.9, respectively. Seventy-three (24.3%) patients had good TTR (≥ 60%), with mean of 70.2 ± 8.7%; while 227 (75.5%) patients with poor TTR had significantly lower mean of 39.5 ± 11.9% (p = 0.006). There was no significant difference in the score of PCS (p = 0.150), MCS (p = 0.919) and each domain of SF-12v2 (p = 0.184 – 0.684) between good and poor TTR, except for social functioning (p = 0.019). The total DASS score was also not significantly different between group (p = 0.779). Similar non-significant difference was also reported in all the DASS sub dimensions (p = 0.502 – 0.699).Conclusions:Majority of the patients on long-term warfarin for NVAF in the current study have poor TTR. Their HRQoL and treatment satisfaction are independent of their TTR. Achieving a good TTR do not compromise the HRQoL and treatment satisfaction. Therefore, appropriate measures should be taken to optimise INR control, failing which direct oral anticoagulant therapy should be considered.


2009 ◽  
Vol 18 (10) ◽  
pp. 1311-1319 ◽  
Author(s):  
Stella Anifantaki ◽  
Tuncay Muge Filiz ◽  
Athanasios Alegakis ◽  
Pinar Topsever ◽  
Adelais Markaki ◽  
...  

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Muzamil Latief ◽  
Manzoor Parry ◽  
Farhat Abbas ◽  
Manjusha Yadla

Abstract Background and Aims Hormonal abnormalities in haemodialysis (HD) patients contribute to quality of life including sexual dysfunction. Whereas Short Form 36 (SF 36) questionnaire deals with the holistic assessment of the quality of life in patients, it is directly impacted by sexual dysfunction or erectile dysfunction in males. In this study we assessed the sex hormone levels in HD patients and its correlation with quality of life (QOL). Method In this single center cross-sectional study, 100 patients (50 males and 50 females) on maintenance HD for more than 6 months were included in the study. In female patients’ sex hormones that included Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH), Prolactin, Estrogen, Progesterone was assessed in midweek early morning blood sample. In male patients LH, FSH and Testosterone were assessed in midweek early morning samples. QOL assessment was done using SF 36 questionnaire. Results Mean age of our study populations was 33.76+/- 7.86 years with male female ratio of 1:1 and mean body mass index of 20.52 ± 2.89 kg/m2. Presumed chronic interstitial nephritis in was the most common cause of end-stage renal disease (76%) in our study followed by Diabetic Kidney disease (21%). In males, mean serum LH, FSH and Testosterone were 8.58 ± 3.56 mIU/ml, 8.9 ± 4.05, 217.46 ± 96.44 ng/dl respectively with 70% patients having testosterone deficiency. In females, mean serum LH, FSH, Prolactin, estrogen and Progesterone levels were 8.61± 3.86 mIU/ml, 8.08 ± 3.70 mIU/ml, 12.35 ± 5.70 ng/ml, 84.56 ± 27.39 pg/ml and 0.31 ± 0.22ng/ml respectively. Mean SF 36 score in our study was 55.37+/-12.22, in males 54.82+/-12.81 and in females 55.93+/-11.70. The prevalence depression was 53% (50% in males and 56% in females) in our study. There was no significant correlation between SF 36 scores and Beck depression inventory (BDI) scores with LH, FSH in both the genders. In males there was positive correlation between SF 36 scores and testosterone level (r= 0.366), and in females positive correlation between SF 36 score and progesterone level in women HD patients (r= 0.549) was seen. There was a negative correlation between BDI score and progesterone level in women (r=0. -510) and negative correlation between BDI score and testosterone in men (r= -0.371). Conclusion QOL as assessed by SF 36 in patients on HD is low. There was positive correlation between SF 36 scores and testosterone level in males and between SF 36 score and progesterone in females.


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