scholarly journals A Rare Case of Fatal Endobronchial Mucormycosis Masquerading as Endobronchial Tuberculosis

Medicina ◽  
2020 ◽  
Vol 56 (2) ◽  
pp. 64
Author(s):  
Minjeong Kim ◽  
Jun Hyeok Lim ◽  
Mihwa Park ◽  
Hyung Keun Cha ◽  
Lucia Kim ◽  
...  

Pulmonary mucormycosis is a relatively rare but often fatal opportunistic fungal infection that occurs mostly in immunocompromised patients. Endobronchial mucormycosis, a distinct clinical form of pulmonary mucormycosis, is very rare, and only a few cases have been reported. The most common bronchoscopic findings in patients with endobronchial mucormycosis are stenosis, erythematous mucosa and airway obstruction. Here, we present a case of fatal endobronchial mucormycosis mimicking actively caseating endobronchial tuberculosis in a young diabetic patient living in a country with an intermediate tuberculosis burden.

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Mohammed Muqeetadnan ◽  
Ambreen Rahman ◽  
Syed Amer ◽  
Salman Nusrat ◽  
Syed Hassan ◽  
...  

Mucormycosis is a rare, but emerging, life-threatening, rapidly progressive, angioinvasive fungal infection that usually occurs in immunocompromised patients. We present a case of pulmonary mucormycosis in a diabetic patient who was on chronic steroid therapy for ulcerative colitis. Early recognition of this diagnosis, along with aggressive management, is critical to effective therapy and patient survival. The delay in diagnosis of this rapidly progressive infection can result in mortality.


2013 ◽  
Vol 57 (7) ◽  
pp. 3340-3347 ◽  
Author(s):  
Guanpingsheng Luo ◽  
Teclegiorgis Gebremariam ◽  
Hongkyu Lee ◽  
Samuel W. French ◽  
Nathan P. Wiederhold ◽  
...  

ABSTRACTMucormycosis is a life-threatening fungal infection almost uniformly affecting diabetics in ketoacidosis or other forms of acidosis and/or immunocompromised patients. Inhalation ofMucoralesspores provides the most common natural route of entry into the host. In this study, we developed an intratracheal instillation model of pulmonary mucormycosis that hematogenously disseminates into other organs using diabetic ketoacidotic (DKA) or cyclophosphamide-cortisone acetate-treated mice. Various degrees of lethality were achieved for the DKA or cyclophosphamide-cortisone acetate-treated mice when infected with different clinical isolates ofMucorales. In both DKA and cyclophosphamide-cortisone acetate models, liposomal amphotericin B (LAmB) or posaconazole (POS) treatments were effective in improving survival, reducing lungs and brain fungal burdens, and histologically resolving the infection compared with placebo. These models can be used to study mechanisms of infection, develop immunotherapeutic strategies, and evaluate drug efficacies against life-threateningMucoralesinfections.


2022 ◽  
Author(s):  
xiaopo wang ◽  
Shiqi Ling ◽  
Guanzhao Liang ◽  
Jianfang Sun

Abstract Diabetes mellitus considered to represent an immunodeficient state significantly predisposes patients to all types of opportunistic invasive fungal infection. However, very few cases of cutaneous alternariosis associated with diabetes have been reported previously. Herein, we describe a rare case of cutaneous alternariosis in an elderly diabetic patient with antecedent local trauma.


Author(s):  
Bouthaina Hammami ◽  
Imen Achour ◽  
Omar Walha ◽  
Ghada Yousfi ◽  
Malek Mnejja ◽  
...  

Mucormycosis is a serious and relatively rare invasive fungal infection. The rhino-orbito-cerebral localization is the most frequent. Mucormycosis of external ear with facial palsy is extremely rare. We describe a case of mucormycosis of the external ear complicated by parotid abscess and facial palsy in a diabetic patient.


Infection ◽  
2020 ◽  
Author(s):  
Daniela Pasero ◽  
Silvana Sanna ◽  
Corrado Liperi ◽  
Davide Piredda ◽  
Gian Pietro Branca ◽  
...  

AbstractSevere acute respiratory syndrome coronavirus 2 infection might induce a significant and sustained lymphopenia, increasing the risk of developing opportunistic infections. Mucormycosis is a rare but severe invasive fungal infection, mainly described in immunocompromised patients. The first case of a patient diagnosed with coronavirus disease (COVID-19) who developed a pulmonary mucormycosis with extensive cavitary lesions is here reported. This case highlights how this new coronavirus might impair the immune response, exposing patients to higher risk of developing opportunistic infections and leading to worse outcomes.


2018 ◽  
Vol 2 (2) ◽  
pp. 33-34
Author(s):  
Shikha Jain ◽  
Bharat Sharma

Mucormycosis is an uncommon but life threatening fungal infection that generally occurs mostly in immunocompromised patients. Patients do not respond to the antibiotics and so the condition may prove to be fatal if not timely detected. In this report, we summarize a case of pulmonary mucormycosis in a patient with diabetes mellitus who was cured using Amphotericin B.


2011 ◽  
Vol 3 (6) ◽  
pp. 405-406
Author(s):  
Dr. Nale Swati S Dr. Nale Swati S ◽  
◽  
Dr.Ghadage Dnyaneshwari P ◽  
Bhore Arvind V

2016 ◽  
Vol 1 (2) ◽  
pp. 33
Author(s):  
Nurul Yaqeen Mohd Esa ◽  
Mohammad Hanafiah ◽  
Marymol Koshy ◽  
Hilmi Abdullah ◽  
Ahmad Izuanuddin Ismail ◽  
...  

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.


2021 ◽  
pp. 014556132110141
Author(s):  
Marios Stavrakas ◽  
Ioannis Koskinas ◽  
Jannis Constantinidis ◽  
Petros D Karkos

Mucormycosis is a type of fungal infection more prevalent among immunosuppressed patients, requires prompt identification and surgical treatment, as it can is associated with local and distant spread. This case is aiming to highlight the importance of early identification of subtle symptoms in immunocompromised patients. The clinician should be aware of fungal sinusitis, consider it in the differential diagnosis, and seek for an ear, nose, and throat opinion.


2021 ◽  
Vol 16 (9) ◽  
pp. 2668-2671
Author(s):  
Sachin Pathare ◽  
Kevin Varghese ◽  
Kajal Limbad
Keyword(s):  

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