scholarly journals Bispectral Index Monitoring and Observer Rating Scale Correlate with Dreaming during Propofol Anesthesia for Gastrointestinal Endoscopies

Medicina ◽  
2021 ◽  
Vol 58 (1) ◽  
pp. 62
Author(s):  
Helena Matus ◽  
Slavica Kvolik ◽  
Andreja Rakipovic ◽  
Vladimir Borzan
Keyword(s):  
Blood Pressure ◽  
Facial Expression ◽  
Bispectral Index ◽  
Gastrointestinal Endoscopy ◽  
Rating Scale ◽  
Point Scale ◽  
Observer Rating ◽  
Registration Number ◽  
Observer Ratings ◽  
The Mean

Background and objectives: Dreaming is a commonly reported side effect of propofol anesthesia. Materials and Methods: We investigated the inci-dence and character of dreams in patients undergoing intravenous propofol anesthesia and cor-related it with an observer rating scale of facial expression on the seven-point scale from pain to smile. A total of 124 patients undergoing gastrointestinal endoscopy were recruited in the pro-spective observational study. Bispectral index (BIS), blood pressure (BP), and pulse were moni-tored. Upon emergence from anesthesia, the patient’s facial expression was rated numerically. Thereafter, patients were asked whether they had dreams and to rate their dreams as pleasant or unpleasant. The mean age of participants was 53; body mass index, 26.17; duration of procedure, 20 min; and average propofol dose, 265 mg. Results: Dreaming was reported by 43% of patients. Dreams were pleasant in all but one patient. There was a significant correlation of the observer’s rating of facial expression with dreaming (r = 0.260; p = 0.004). Dreamers had higher scores of observer rating of facial expression (1 (0–2) vs. 0.5 (0–1), p = 0.006). Conclusions: BIS values were lower in the dreamers vs. non-dreamers 2 min after the endoscopy started (48 (43–62) vs. 59 (45–71), p = 0.038). Both BIS and observer ratings correlate with dreaming in patients undergoing gastrointestinal endos-copy. Trial registration number: NCT04235894.

Adolescent Males' Ratings of Being Understood by Fathers, Best Friends and Significant others

1977 ◽  
Vol 40 (3_suppl) ◽  
pp. 1079-1082 ◽  
Author(s):  
Leverett Millen ◽  
Samuel Roll
Keyword(s):  
Rating Scale ◽  
Significant Others ◽  
Adolescent Males ◽  
Point Scale ◽  
Complete Understanding ◽  
Best Friends ◽  
Male College ◽  
Male Friend ◽  
The Mean ◽  
Favorite Teacher

An adolescent male's relationship with his father and his best friend is investigated. 413 male college students filled out a rating scale in which each reported how much he felt understood by his father, mother, by best male friend, best female friend, by favorite teacher, and by any additional person he wished to designate. The ratings were on a 7-point scale, ranging from “virtually a total stranger” to “complete understanding.” The mean ratings for a son's feeling of being understood by significant others was analyzed by a procedure for the multiple comparison of means described by Games (1971). The sons felt relatively more understood by their best friends than they did by their fathers. Implications of the findings for a theory of friendship and for psychotherapy with adolescent males are discussed.

Reliability of single office blood pressure measurements

Heart ◽  
2018 ◽  
Vol 104 (14) ◽  
pp. 1173-1179 ◽  
Author(s):  
Thilo Burkard ◽  
Michael Mayr ◽  
Clemens Winterhalder ◽  
Licia Leonardi ◽  
Jens Eckstein ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Measurement ◽  
Office Blood Pressure ◽  
White Coat Hypertension ◽  
Masked Hypertension ◽  
Short Term ◽  
Cross Sectional ◽  
Registration Number ◽  
The Mean ◽  
The Difference

ObjectivesStandard operating procedures for office blood pressure measurement (OBPM) vary greatly between guidelines and studies. We aimed to compare the difference between a single OBPM and the mean of the three following measurements. Further, we studied how many patients with possible hypertension may be missed due to short-term masked hypertension (STMH) and how many might be overdiagnosed due to short-term white coat hypertension (STWCH).Design and settingIn this cross-sectional, single-centre trial, 1000 adult subjects were enrolled. After 5 min of rest, four sequential standard OBPMs were performed at 2 min intervals in a quiet room in sitting position. We compared the first (fBPM) to the mean of the second to fourth measurement (mBPM). STMH was defined as fBPM <140 mm Hg systolic and <90 mm Hg diastolic and mBPM systolic ≥140 mm Hg or diastolic ≥90 mm Hg. STWCH was defined as fBPM systolic ≥140 mm Hg or diastolic ≥90 mm Hg and mBPM <140 mm Hg systolic and <90 mm Hg diastolic.ResultsComplete measurements were available in 802 subjects. Between fBPM and mBPM, 662 (82.5%), 441 (55%) and 208 (25.9%) subjects showed a difference in systolic and 531 (66.2%), 247 (30.8%) and 51 (6.4%) in diastolic blood pressure (BP) values of >2 mm Hg, >5 mm Hg and >10 mm Hg, respectively. In 3.4% of initially normotensives STMH and in 34.3% of initially hypertensives, STWCH was apparent.ConclusionsThere are significant differences between a single OBPM and the mean of consecutive BP measurements. Our study provides evidence that a single OBPM should not be the preferred method and should be discouraged in future guidelines.Trial registration numberNCT02552030;Results.

scholarly journals Twelve-month analgesia and rescue, by cooled radiofrequency ablation treatment of osteoarthritic knee pain: results from a prospective, multicenter, randomized, cross-over trial

2019 ◽  
Vol 44 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Tim Davis ◽  
Eric Loudermilk ◽  
Michael DePalma ◽  
Corey Hunter ◽  
David A Lindley ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Knee Pain ◽  
Rating Scale ◽  
Numeric Rating Scale ◽  
Clinical Trial Registration ◽  
Provide Pain Relief ◽  
Registration Number ◽  
The Mean ◽  
Numeric Rating

Background and objectivesAs a follow-up to the 6-month report,12 this study investigated the analgesic effect of cooled radiofrequency ablation (CRFA) in patients with knee osteoarthritis (OA) 12 months postintervention and its ability to provide pain relief in patients who experienced unsatisfactory effects of intra-articular steroid injection (IAS).MethodsSeventy-eight per cent (52/67) of patients originally treated with CRFA were evaluated at 12 months, while at 6 months post-IAS, 82% (58/71) of those patients crossed over to CRFA and assessed 6 months later.ResultsAt 12 months, 65% of the original CRFA group had pain reduction ≥50%, and the mean overall drop was 4.3 points (p<0.0001) on the numeric rating scale. Seventy-five per cent reported ‘improved’ effects. The cross-over group demonstrated improvements in pain and functional capacity (p<0.0001). No unanticipated adverse events occurred.ConclusionsThis study demonstrates that analgesia following CRFA for OA knee pain could last for at least 12 months and could rescue patients who continue to experience intolerable discomfort following IAS.Clinical trial registrationThe ClinicalTrials.gov registration number for this study is NCT02343003.

scholarly journals The effect of Bispectral index monitoring during induction of anesthesia on the amount of propofol consumtion in patients candidates for surgery

2021 ◽  
Vol 7 (4) ◽  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
General Anesthesia ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Bispectral Index ◽  
Time Points ◽  
Arterial Blood ◽  
Significant Difference ◽  
The Mean

Objectives: This study investigated the effect of Bispectral index (BIS) during induction of anesthesia on the amount of propofol consumed in patient candidates for surgery. Methods: This double-blind clinical trial study was performed on patients undergoing elective surgery under general anesthesia in a hospital. Patients were divided into case and control groups. After being transferred to the operating room, patients were monitored including ECG 3 or 5 leads, non-invasive barometer, and pulse oximetry. Mean arterial blood pressure and heart rate were measured before and after induction, immediately, and 5 minutes after intubation. The dose of propofol was then measured. Data analysis was performed by SPSS software version 20. Results: In the present study, no significant difference was found between the mean age and gender (P> 0.05). The amount of propofol consumed in the case group was significantly lower than the control group (P = 0.039) and the amount of propofol consumed in men and women was not statistically significant (P <0.05). Mean arterial blood pressure before induction was not statistically significant between the two groups (P = 0.83). However, a statistically significant difference was found in the mean arterial blood pressure of the patients during the 4-time points (P = 0.001). There was no statistically significant difference in heart rate between patients before induction (P = 0.48). Statistical analysis of data by ANOVA test did not show a significant interaction between time and group (P = 0.418 and P = 0.74). However, a statistically significant difference was found in patients' heart rate during the 4-time points (F = 7.59 and P = 0.001). Moreover, a significant increase was observed in heart rate after intubation in both groups (P = 0.001). Conclusion: The use of BIS can be effective in reducing the amount of propofol consumed and its side effects. The condition of patients under general anesthesia can be improved by BIS, resulting in the improvement of their subsequent condition.

scholarly journals Real-world evidence on the strategy of olmesartan-based triple single-pill combination in Korean hypertensive patients: a prospective, multicenter, observational study (RESOLVE-PRO)

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Il Suk Sohn ◽  
Sang-Hyun Ihm ◽  
Gee Hee Kim ◽  
Sang Min Park ◽  
Bum-Kee Hong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Observational Study ◽  
Rating Scale ◽  
Medication Possession Ratio ◽  
Hypertensive Patients ◽  
Multicenter Observational Study ◽  
Single Pill ◽  
The Mean ◽  
Observation Period

Abstract Background In this prospective, multicenter, non-comparative observational study, the effectiveness and safety of the triple single-pill combination (SPC) of olmesartan/amlodipine/hydrochlorothiazide (OM/AML/HCTZ) were evaluated in a real clinical practice setting in Korean patients with essential hypertension. Methods A total of 3752 patients were enrolled and followed for 12 months after administration of OM/AML/HCTZ. Primary endpoint was change from baseline to month 6 in the mean systolic blood pressure (SBP). Secondary endpoints included changes from baseline in the mean SBP at month 3, 9, 12 and the mean diastolic blood pressure (DBP) at month 3, 6, 9, 12; changes in the mean SBP/DBP according to age and underlying risk factors; and blood pressure control rate (%) at different time points. Adherence to and satisfaction with OM/AML/HCTZ treatment among patients and physicians were assessed by medication possession ratio (MPR) and numeric rating scale, respectively, as exploratory endpoints. Safety was evaluated by the incidence and severity of adverse events (AEs) as well as the discontinuation rate due to AEs. Results OM/AML/HCTZ administration led to significant reductions in the mean SBP/DBP by 11.5/6.6, 12.3/7.0, 12.3/7.2, and 12.8/7.4 mmHg from baseline to month 3, 6, 9 and 12, respectively (P < 0.0001). The BP reductions were maintained throughout the 1-year observation period in all patients with different age groups and risk factors (diabetes mellitus, cardiovascular disease, and renal disease). The BP control rate (%) of < 140/90 mmHg was 65.9, 67.9, 68.9, and 70.6% at month 3, 6, 9, and 12, respectively. The mean MPR during the observation period was 0.96. The safety results were consistent with the previously reported safety profile of OM/AML/HCTZ. Conclusions Treatment with the triple SPC of OM/AML/HCTZ demonstrated significant effectiveness in reducing SBP/DBP and achieving target BP control with high adherence over the 1-year observation period in Korean hypertensive patients and was well-tolerated. Trial registration CRIS, KCT0002196, Registered 3 May 2016.

Testing the Significance of the Agreement Among Observers

1968 ◽  
Vol 11 (1) ◽  
pp. 5-17 ◽  
Author(s):  
Martin A. Young ◽  
Tom D. Downs
Keyword(s):  
Rating Scale ◽  
Intraclass Correlation ◽  
Speech Disorder ◽  
Interquartile Range ◽  
Speech Pathology ◽  
Observer Ratings

Ratings by observers are often used in speech pathology to measure complex speech dimensions; this seems reasonable since a speech “disorder” represents the product of an observer’s evaluation and a speaker’s performance. An index of the validity of these evaluations may be estimated by the amount of agreement among the observers. In this paper, the semi-interquartile range and the intraclass correlation are discussed as possible indices of agreement, and another index is suggested, based on the range of observer ratings. Under the assumption that the distribution of ratings is uniform when ratings are randomly assigned, that is, the observers show no agreement, tables were constructed to indicate the probability of any range for selected numbers of observers and rating scale categories. Some applications for this index concern the training of observers, estimating the number of observers needed, and the construction of master scales.

RELATIONSHIP BETWEEN CARDIOVASCULAR DISEASES AND ANATOMOSIS OF ARTERIOVENOUS FISTULAR IN PATIENTS WITH REGULARLY HEMODIALYSIS

2017 ◽  
pp. 88-92
Author(s):  
Van Hien Pham ◽  
Huu Vu Quang Nguyen ◽  
Tam Vo
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Cardiovascular Diseases ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Negative Correlation ◽  
Mean Value ◽  
The Mean

Background: Cardiovascular diseases are the leading cause of death in patients with chronic renal failure. When a patient undergoes dialysis, making AVF or AVG causes cardiovascular events. Understanding the relationship between complications: hypertension, heart failure, AVF or AVG (formation time, position, diameter) helps us monitor, detect, prevent and treatment of complications to limit the risk of death in patients with dialysis. Objective: Relationship between cardiovascular diseases and anatomosis of arteriovenous fistular in patients with regularly hemodialysis at Cho Ray Hospital. Methods: A cross-sectional study was conducted at Cho Ray Hospital from 2015 to 2016. The survey some cardiovascular diseases are done by clinical examination, tests for diagnostic imaging such as X-ray, electrocardiogram and echocardiogram: heart and diameter of anastomosis AVF, AVG. Results: The study population included 303 patients with chronic renal failure who were dialysis. Of which, patients aged 25-45 accounted for the highest proportion (43.9%). The proportion of male and female patients was similar (48.5% and 51.5% respectively). The mean value of systolic blood pressure on patients made AVF, AVG less than 12 months is higher than patients made AVF, AVG over 12 months, and there is negative correlation (r = -0.43) between AVF, AVG and systolic blood pressure (p <0.05). The mean value of diastolic blood pressure on patients made AVF, AVG less than 12 months is lower than patients made AVF, AVG over 12 months, and and there is positive correlation (r = -0.43) between AVF, AVG and diastolic blood pressure (p <0.05) (p <0.05). The prevalence of patients with heart failure made AVF, AVG over 12 months is higher than that of the under 12 months group, there is a negative correlation (r = - 0.43) between AVF, AVG diameter and EF index (p <0.05). Conclusion: It is important to note the diameter of anastomosis AVF, AVG in patients with chronic renal failure dialysis to limit cardiovascular complications, especially heart failure. Key words: Chronic kidney disease, hemodialysis.

Effect of the Interaction Between Hypertension and Cerebral White Matter Changes on the Progression of Alzheimer Disease

2018 ◽  
Vol 15 (14) ◽  
pp. 1354-1360 ◽  
Author(s):  
Ping-Song Chou ◽  
Yi-Hui Kao ◽  
Meng-Ni Wu ◽  
Mei-Chuan Chou ◽  
Chun-Hung Chen ◽  
...  
Keyword(s):  
White Matter ◽  
Alzheimer Disease ◽  
Rating Scale ◽  
Vital Role ◽  
Independent Effect ◽  
Cerebral White Matter ◽  
Clinical Dementia Rating ◽  
White Matter Changes ◽  
Age Related ◽  
The Mean

Background: Cerebrovascular pathologies and hypertension could play a vital role in Alzheimer disease (AD) progression. However, whether cerebrovascular pathologies and hypertension accelerate the AD progression through an independent or interaction effect is unknown. Objective: To investigate the effect of the interactions of cerebrovascular pathologies and hypertension on AD progression. Method: A retrospective longitudinal study was conducted to compare AD courses in patients with different severities of cerebral White Matter Changes (WMCs) in relation to hypertension. Annual comprehensive psychometrics were performed. WMCs were rated using a rating scale for Age-related WMCs (ARWMC). Results: In total, 278 patients with sporadic AD were enrolled in this study. The mean age of the patients was 76.6 ± 7.4 years, and 166 patients had hypertension. Among AD patients with hypertension, those with deterioration in clinical dementia rating-sum of box (CDR-SB) and CDR had significantly severe baseline ARWMC scales in total (CDR-SB: 5.8 vs. 3.6, adjusted P = 0.04; CDR: 6.4 vs. 4.4, adjusted P = 0.04) and frontal area (CDR-SB: 2.4 vs. 1.2, adjusted P = 0.01; CDR: 2.4 vs. 1.7, adjusted P < 0.01) compared with those with no deterioration in psychometrics after adjustment for confounders. By contrast, among AD patients without hypertension, no significant differences in ARWMC scales were observed between patients with and without deterioration. Conclusion: The effect of cerebrovascular pathologies on AD progression between those with and without hypertension might differ. An interaction but not independent effect of hypertension and WMCs on the progression of AD is possible.

Sign in / Sign up

Export Citation Format

Share Document