scholarly journals A Green-emitting Fluorescent Probe Based on a Benzothiazole Derivative for Imaging Biothiols in Living Cells

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 411 ◽  
Author(s):  
Xiaohua Ma ◽  
Yuanqiang Hao ◽  
Jiaxiang Liu ◽  
Guoguang Wu ◽  
Lin Liu
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
A549 Cells ◽  
Living Cells ◽  
Fluorescence Signal ◽  
Sulfonate Group ◽  
Turn On ◽  
Highly Sensitive ◽  
Confocal Fluorescence ◽  
Confocal Fluorescence Imaging

A new green-emitting fluorescent probe 1 was developed for biothiol detection. The sensing mechanism was considered to be biothiol-induced cleavage of the 2,4-dinitrobenzene- sulfonate group in probe 1 and resulting inhibition of the probe’s photoinduced electron transfer (PET) process. Probe 1 exhibited favorable properties such as excellent selectivity, highly sensitive (0.12 µM), large Stokes shift (117 nm) and a remarkable turn-on fluorescence signal (148-fold). Furthermore, confocal fluorescence imaging indicated that probe 1 was membrane-permeable and suitable for visualization of biothiols in living A549 cells.

scholarly journals A fast-responsive two-photon fluorescent probe for in vivo imaging superoxide radical anion with a large stokes shift

RSC Advances ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 4125-4129 ◽  
Author(s):  
Yunpeng Xuan ◽  
Jianbo Qu
Keyword(s):  
Fluorescent Probe ◽  
Radical Anion ◽  
Superoxide Radical ◽  
Stokes Shift ◽  
Living Cells ◽  
Fluorescence Signal ◽  
Superoxide Radical Anion ◽  
Two Photon ◽  
Turn On

A novel and simple two-photon fluorescent probe NS-O for the detection of superoxide radical anion (O2˙−) with a large turn-on fluorescence signal is constructed to monitor endogenous superoxide radical anions in living cells, tissues and zebrafish.

A nitroreductase and acidity detecting dual functional ratiometric fluorescent probe for selectively imaging tumor cells

2018 ◽  
Vol 16 (17) ◽  
pp. 3266-3272 ◽  
Author(s):  
Zhaoshuai He ◽  
Yajie Chou ◽  
Hanxin Zhou ◽  
Han Zhang ◽  
Tanyu Cheng ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Fluorescent Probe ◽  
Fluorescence Imaging ◽  
A549 Cells ◽  
Living Cells ◽  
Acidic Environment ◽  
Dual Functional ◽  
Confocal Fluorescence ◽  
Confocal Fluorescence Imaging ◽  
Ratiometric Fluorescent Probe

A dual functional ratiometric fluorescent probe can obviously distinguish acidity, nitroreductase, and nitroreductase in an acidic environment. Confocal fluorescence imaging of A549 cells indicates the probe can detect acidity and expressed nitroreductase in living cells.

A phenanthrene[9,10-d]imidazole-phenol-based fluorescent probe combined ESIPT and AIE for “turn-on” detection of Cu2+ with a green-emitting and improved stokes shift and its application

2021 ◽  
Author(s):  
Jiahui Du ◽  
Bing Zhao ◽  
Wei Kan ◽  
Haochun Yin ◽  
Tianshu Song ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Fluorescent Sensors ◽  
Turn On ◽  
Highly Sensitive

Development of highly sensitive and selective fluorescent sensors toward Cu2+ has gained considerable attention in view of its application of environmental and biological fields. However, the strategy of sensing by...

A highly sensitive turn-on fluorescent probe for real-time detecting hypochlorite and its application in living cells

Talanta ◽  
2020 ◽  
Vol 209 ◽  
pp. 120548 ◽  
Author(s):  
Yilin Zhu ◽  
Kangnan Wang ◽  
Xiangwen Wu ◽  
Yanan Sun ◽  
Xiangshuo Gong ◽  
...  
Keyword(s):  
Real Time ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Turn On ◽  
Highly Sensitive

A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

2014 ◽  
Vol 38 (12) ◽  
pp. 6198-6204 ◽  
Author(s):  
Jiun-Ting Yeh ◽  
Parthiban Venkatesan ◽  
Shu-Pao Wu
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Green Fluorescence ◽  
Turn On ◽  
Highly Sensitive

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

A novel “turn-on” fluorescent probe with a large stokes shift for homocysteine and cysteine: Performance in living cells and zebrafish

2018 ◽  
Vol 259 ◽  
pp. 233-240 ◽  
Author(s):  
Haohan Song ◽  
Junli Zhang ◽  
Xiao Wang ◽  
Yanmei Zhou ◽  
Chenggong Xu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Living Cells ◽  
Large Stokes Shift ◽  
Turn On

A novel colorimetric/fluorescence dual-channel sensor based on NBD for the rapid and highly sensitive detection of cysteine and homocysteine in living cells

2016 ◽  
Vol 8 (11) ◽  
pp. 2420-2426 ◽  
Author(s):  
Youming Shen ◽  
Xiangyang Zhang ◽  
Youyu Zhang ◽  
Chunxiang Zhang ◽  
Junling Jin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Optical Sensing ◽  
Living Cells ◽  
Sensitive Detection ◽  
Turn On ◽  
Dual Channel ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A novel and simple turn-on fluorescent probe bearing NBD and benzaldehyde fragments for the rapid optical sensing of biothiols has been designed and synthesized.

A highly selective ESIPT-based fluorescent probe with a large Stokes shift for the turn-on detection of cysteine and its application in living cells

2019 ◽  
Vol 160 ◽  
pp. 48-57 ◽  
Author(s):  
Huace Sheng ◽  
Yonghong Hu ◽  
Yi Zhou ◽  
Shimin Fan ◽  
Yang Cao ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Living Cells ◽  
Large Stokes Shift ◽  
Turn On

A novel near-infrared and naked-eyes turn on fluorescent probe for detection of biothiols with a large Stokes shift and its application in living cells

2018 ◽  
Vol 10 (32) ◽  
pp. 3991-3999 ◽  
Author(s):  
Wang Zhang ◽  
Gu Weijing ◽  
Tian Cheng ◽  
Bingxiang Wang ◽  
Yuliang Jiang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Stokes Shift ◽  
Living Cells ◽  
Selective Detection ◽  
Large Stokes Shift ◽  
Turn On

A novel turn-on fluorescent probe (DDND) for highly selective detection of biothiols over other amino acids was synthesized and investigated in this work, which used the 2,4-dinitrobenzenesulfonyl group as a fluorescent quencher.

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