scholarly journals Bioanalytical HPLC Applications of In-Tube Solid Phase Microextraction: A Two-Decade Overview

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2096 ◽  
Author(s):  
Natalia Manousi ◽  
Paraskevas D. Tzanavaras ◽  
Constantinos K. Zacharis
Keyword(s):  
Solid Phase Microextraction ◽  
Considerable Increase ◽  
Solid Phase ◽  
Time Frame ◽  
Review Article ◽  
Treatment Technique ◽  
Sample Treatment ◽  
Research Groups ◽  
The Past ◽  
Bioanalytical Applications

In-tube solid phase microextraction is a cutting-edge sample treatment technique offering significant advantages in terms of miniaturization, green character, automation, and preconcentration prior to analysis. During the past years, there has been a considerable increase in the reported publications, as well as in the research groups focusing their activities on this technique. In the present review article, HPLC bioanalytical applications of in-tube SPME are discussed, covering a wide time frame of twenty years of research reports. Instrumental aspects towards the coupling of in-tube SPME and HPLC are also discussed, and detailed information on materials/coatings and applications in biological samples are provided.

scholarly journals Strategies and Efforts towards the Total Synthesis of Palhinine Alkaloids

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4211
Author(s):  
Yu-Yan Liang ◽  
Shi-Chao Lu ◽  
Ya-Ling Gong ◽  
Shu Xu
Keyword(s):  
Total Synthesis ◽  
Review Article ◽  
Research Groups ◽  
Asymmetric Total Synthesis ◽  
Carbon Cage ◽  
Total Syntheses ◽  
The Past ◽  
Lycopodium Alkaloids

The palhinine family of Lycopodium alkaloids were first reported in 2010, which feature an intriguing isotwistane carbon cage and a nine-membered azonane ring. It is noteworthy that the tetracyclic 5/6/6/9 skeleton was unprecedented in Lycopodium alkaloids before their seminal discovery. Over the past decade, extensive synthetic efforts stemming from seven research groups have resulted in two racemic total syntheses to date. This review article takes the opportunity to survey these efforts and achievements so as to promote further research towards the asymmetric total synthesis of palhinine alkaloids.

Bioanalytical Applications of Solid-Phase Microextraction

ChemInform ◽  
2007 ◽  
Vol 38 (18) ◽  
Author(s):  
Florin Marcel Musteata ◽  
Janusz Pawliszyn
Keyword(s):  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Bioanalytical Applications

scholarly journals Recent Advances in In Vivo SPME Sampling

Separations ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 6 ◽  
Author(s):  
Riboni ◽  
Fornari ◽  
Bianchi ◽  
Careri
Keyword(s):  
Solid Phase Microextraction ◽  
Biomarker Discovery ◽  
State Of The Art ◽  
Solid Phase ◽  
Review Article ◽  
Tissue Sampling ◽  
Mass Spectrometers ◽  
Endogenous Compounds ◽  
Living Organisms

In vivo solid-phase microextraction (SPME) has been recently proposed for the extraction, clean-up and preconcentration of analytes of biological and clinical concern. Bioanalysis can be performed by sampling exo- or endogenous compounds directly in living organisms with minimum invasiveness. In this context, innovative and miniaturized devices characterized by both commercial and lab-made coatings for in vivo SPME tissue sampling have been proposed, thus assessing the feasibility of this technique for biomarker discovery, metabolomics studies or for evaluating the environmental conditions to which organisms can be exposed. Finally, the possibility of directly interfacing SPME to mass spectrometers represents a valuable tool for the rapid quali- and quantitative analysis of complex matrices. This review article provides a survey of in vivo SPME applications focusing on the extraction of tissues, cells and simple organisms. This survey will attempt to cover the state-of- the-art from 2014 up to 2019.

scholarly journals New Insights on Volatile Components of Vanilla planifolia Cultivated in Taiwan

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3608
Author(s):  
Chih-Hsin Yeh ◽  
Kai-Yi Chen ◽  
Chia-Yi Chou ◽  
Hsin-Yi Liao ◽  
Hsin-Chun Chen
Keyword(s):  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Volatile Components ◽  
Processing Conditions ◽  
Vanilla Planifolia ◽  
Total Volatile ◽  
Dekkera Bruxellensis ◽  
The Past ◽  
Different Strains ◽  
Different Origins

Vanilla (Vanilla planifolia) is a precious natural flavoring that is commonly used throughout the world. In the past, all vanilla used in Taiwan was imported; however, recent breakthroughs in cultivation and processing technology have allowed Taiwan to produce its own supply of vanilla. In this study, headspace solid-phase microextraction (HS-SPME) combined with GC-FID and GC-MS was used to analyze the volatile components of vanilla from different origins produced in Taiwan under different cultivation and processing conditions. The results of our study revealed that when comparing different harvest maturities, the composition diversity and total volatile content were both higher when the pods were matured for more than 38 weeks. When comparing different killing conditions, we observed that the highest vanillin percentage was present after vanilla pods were killed three times in 65 °C treatments for 1 min each. From the experiment examining the addition of different strains, the PCA results revealed that the volatiles of vanilla that was processed with Dekkera bruxellensis and Bacillus subtilis was clearly distinguished from which obtained by processing with the other strains. Vanilla processed with B. subtilis contained 2-ethyl-1-hexanol, and this was not detected in other vanillas. Finally, when comparing the vanillin percentage from seven different regions in Taiwan, vanilla percentage from Taitung and Taoyuan Longtan were the highest.

scholarly journals Solid Phase Microextraction Devices Prepared on Plastic Support as Potential Single-Use Samplers for Bioanalytical Applications

2015 ◽  
Vol 87 (19) ◽  
pp. 9722-9730 ◽  
Author(s):  
Nathaly Reyes-Garcés ◽  
Barbara Bojko ◽  
Dietmar Hein ◽  
Janusz Pawliszyn
Keyword(s):  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Single Use ◽  
Bioanalytical Applications

scholarly journals Returning to Nature for the Design of Sorptive Phases in Solid-Phase Microextraction

Separations ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 2 ◽  
Author(s):  
Gabriela Mafra ◽  
María Teresa García-Valverde ◽  
Jaime Millán-Santiago ◽  
Eduardo Carasek ◽  
Rafael Lucena ◽  
...  
Keyword(s):  
Natural Products ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Negative Impact ◽  
Raw Materials ◽  
Sample Treatment ◽  
General Picture ◽  
Treatment Techniques ◽  
Microextraction Techniques ◽  
Key Terms

Green analytical chemistry principles aim to minimize the negative impact of analytical procedures in the environment, which can be considered both at close (to ensure the safety of the analysts) and global (to conserve our natural resources) levels. These principles suggest, among other guidelines, the reduction/minimization of the sample treatment and the use of renewable sources when possible. The first aspect is largely fulfilled by microextraction, which is considered to be among the greenest sample treatment techniques. The second consideration is attainable if natural products are used as raw materials for the preparation of new extraction phases. This strategy is in line with the change in our production system, which is being gradually moved from a linear model (take–make–dispose) to a circular one (including reusing and recycling as key terms). This article reviews the potential of natural products as sorbents in extraction and microextraction techniques from the synergic perspectives of two research groups working on the topic. The article covers the use of unmodified natural materials and the modified ones (although the latter has a less green character) to draw a general picture of the usefulness of the materials.

scholarly journals Miniaturized sample preparation based on carbon nanostructures

2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Soledad Cárdenas
Keyword(s):  
Analytical Chemistry ◽  
Carbon Nanoparticles ◽  
Carbon Nanostructures ◽  
Solid Phase ◽  
Present Situation ◽  
Review Article ◽  
Sample Treatment ◽  
Phase Extraction ◽  
Analytical Chemist ◽  
Potential Influence

AbstractThe evolution of analytical methodologies has been driven by the objective to reduce the complexity of sample treatment while increasing the efficiency of the overall analytical process. For this reason, the analytical chemist takes into consideration advances in other scientific areas and systematically evaluates the potential influence that such discoveries might have on its own discipline. This is the present situation with nanostructured materials, which have already been recognized as a revolution in many scientific and technological fields, including analytical chemistry. Carbon nanoparticles have been a cornerstone in the advance of miniaturization of analytical processes. This review article considers the contribution of four reference carbon nanoparticles: nanotubes, graphene, nanohorns/ cones and fullerenes, in the context of miniaturized sample treatment, where their outstanding sorbent properties are by far the most exploited in (micro) solid phase extraction.

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