scholarly journals Solvent-Free Synthesis of 2,5Bis((dimethylamino)methylene)cyclopentanone

2019 ◽  
Vol 2 (3) ◽  
pp. 69
Author(s):  
Martins ◽  
Coelho
Keyword(s):  
Dimethyl Acetal ◽  
Solvent Free ◽  
High Yield ◽  
Condensation Products ◽  
Ketocyanine Dyes ◽  
Solvent Free Synthesis ◽  
Reaction Profile

Available protocols for the synthesis of ketocyanine dyes precursor 2,5bis((dimethylamino)methylene)cyclopentanone are not straightforward and the reported yields are low to moderate. The important feature in the synthesis of this product through organocatalyzed condensation of cyclopentanone and N,N-Dimethylformamide dimethyl acetal is the removal of methanol produced during the reaction. By studying the reaction profile, in particular the selectivity for the formation of mono- and bis-condensation products, a high yield of the desired product can be obtained through an operationally simple and solvent-free protocol.

scholarly journals A Brief Review on Solvent-Free Synthesis of Zeolites

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 788
Author(s):  
Jinlin Mei ◽  
Aijun Duan ◽  
Xilong Wang
Keyword(s):  
High Efficiency ◽  
Raw Materials ◽  
Solvent Free ◽  
High Yield ◽  
Control Synthesis ◽  
Mechanical Mixing ◽  
Synthesis Mechanism ◽  
Wastewater Pollution ◽  
Low Efficiency ◽  
Solvent Free Synthesis

The traditional hydrothermal method to prepare zeolite will inevitably use a large amount of water as a solvent, which will lead to higher autogenous pressure, low efficiency, and wastewater pollution. The solvent-free method can be used to synthesize various types of zeolites by mechanical mixing, grinding, and heating of solid raw materials, which exhibits the apparent advantages of high yield, low pollution, and high efficiency. This review mainly introduces the development process of solvent-free synthesis, preparation of hierarchical zeolite, morphology control, synthesis mechanism and applications of solvent-free methods. It can be believed that solvent-free methods will become a research focus and have enormous industrial application potential.

scholarly journals A Facile Solvent Free Synthesis of 3-arylidenechroman-4-ones Using Grinding Technique

2012 ◽  
Vol 9 (3) ◽  
pp. 1251-1256 ◽  
Author(s):  
Suresh Kumar ◽  
Jagdish K. Makrandi
Keyword(s):  
Polyphosphoric Acid ◽  
Cold Water ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Environmentally Benign ◽  
High Yield ◽  
Solvent Free Conditions ◽  
Microwave Irradiations ◽  
Grinding Technique ◽  
Solvent Free Synthesis

An efficient method for the synthesis of 3-arylidenechroman-4-ones has been developed under solvent free conditions using grinding technique. Grinding of variously substituted chroman-4-ones with aromatic aldehydes in presence of anhydrous barium hydroxide at room temperature give 3-arylidenechroman-4-ones in high yield (75-92%). Products are obtained by just acidification of the reaction mixture in ice cold water. Reaction in solid state, with enhanced rate, high selectivity and manipulative simplicity are the attractive features of this environmentally benign protocol. The chroman-4-one derivatives required for the reaction have been obtained by polyphosphoric acid (PPA) catalysed cyclisation of phenoxypropanoic acids under microwave irradiations.

Solvent-free synthesis and reactivity of nickel(ii) borohydride and nickel(ii) hydride

2019 ◽  
Vol 21 (10) ◽  
pp. 2752-2758 ◽  
Author(s):  
Sakthi Raje ◽  
Raja Angamuthu
Keyword(s):  
Transition Metal ◽  
Metal Hydrides ◽  
High Reactivity ◽  
Solvent Free ◽  
High Yield ◽  
Organic Transformations ◽  
Transition Metal Hydrides ◽  
Solvent Free Synthesis

Transition metal-hydrides are highly useful in organic transformations of industrial importance yet synthesizing them or their precursor metal-borohydrides in high yield is cumbersome due to their high reactivity and sensitivity towards air and many common solvents.

Solvent-free synthesis of monodisperse Cu nanoparticles by thermal decomposition of an oleylamine-coordinated Cu oxalate complex

2018 ◽  
Vol 47 (15) ◽  
pp. 5342-5347 ◽  
Author(s):  
Takanari Togashi ◽  
Masato Nakayama ◽  
Atsuki Hashimoto ◽  
Manabu Ishizaki ◽  
Katsuhiko Kanaizuka ◽  
...  
Keyword(s):  
Thermal Decomposition ◽  
Solvent Free ◽  
High Yield ◽  
Cu Nanoparticles ◽  
Oxalate Complex ◽  
Solvent Free Synthesis

Monodisperse Cu nanoparticles are synthesized via the thermal decomposition of an oleylamine-coordinated Cu oxalate complex in high yield (∼90%).

scholarly journals Solvent Free Synthesis of Chalcones and their Antibacterial Activities

2005 ◽  
Vol 2 (4) ◽  
pp. 224-227 ◽  
Author(s):  
K. Rajendra K. Saini ◽  
S. Amit Choudhary ◽  
Yogesh. C. Joshi ◽  
P. Joshi
Keyword(s):  
Addition Product ◽  
Antibacterial Activities ◽  
Solvent Free ◽  
High Yield ◽  
Gram Negative Bacteria ◽  
High Melting ◽  
Melting Points ◽  
Gram Negative ◽  
High Yields ◽  
Solvent Free Synthesis

The solvent free synthesis of six chalcones was carried out by grinding the piperanal and the acetophenone (unsubstituted, 4-methyl, 4-methoxy, 4-bromo, 4-nitro, 3-chloro) in the presence of solid sodium hydroxide with a mortar and pestle. In general, the chalcones were obtained in high yield and high purity. Minor quantities of Ketol and Michael addition product were easily removed by recrystallization. The result indicates a correlation between the success of the solvent-free synthesis and melting point of the chalcone. Chalcone with relatively high melting points (higher than 80°C) were obtained in high yields. The two chalcones that could not be produced in good yields were having relatively low melting points. They have been screened for their antibacterial activity against Gram positive and Gram negative bacteria.

scholarly journals NaHSO4-SiO2-Promoted Solvent-Free Synthesis of Benzoxazoles, Benzimidazoles, and Benzothiazole Derivatives

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
K. Ravi Kumar ◽  
P. V. V. Satyanarayana ◽  
B. Srinivasa Reddy
Keyword(s):  
Catalytic Amount ◽  
Solvent Free ◽  
High Yield ◽  
Acyl Chlorides ◽  
Benzothiazole Derivatives ◽  
Sodium Hydrogen ◽  
Solvent Free Conditions ◽  
Hydrogen Sulphate ◽  
Solvent Free Synthesis

An efficient protocol has been developed for the preparation of a library of benzoxazole, benzimidazole, and benzothiazole derivatives from reactions of acyl chlorides witho-substituted aminoaromatics in the presence of catalytic amount of silica-supported sodium hydrogen sulphate under solvent-free conditions. Simple workup procedure, high yield, easy availability, reusability, and use of ecofriendly catalyst are some of the striking features of the present protocol.

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