scholarly journals Cubic-Phase Metasurface for Three-Dimensional Optical Manipulation

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1730
Author(s):  
Hsin Yu Kuo ◽  
Sunil Vyas ◽  
Cheng Hung Chu ◽  
Mu Ku Chen ◽  
Xu Shi ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Visible Region ◽  
Axial Direction ◽  
Spatial Light Modulators ◽  
Biological Research ◽  
Optical Manipulation ◽  
Cubic Phase ◽  
Self Healing ◽  
Airy Beam ◽  
3D Manipulation

The optical tweezer is one of the important techniques for contactless manipulation in biological research to control the motion of tiny objects. For three-dimensional (3D) optical manipulation, shaped light beams have been widely used. Typically, spatial light modulators are used for shaping light fields. However, they suffer from bulky size, narrow operational bandwidth, and limitations of incident polarization states. Here, a cubic-phase dielectric metasurface, composed of GaN circular nanopillars, is designed and fabricated to generate a polarization-independent vertically accelerated two-dimensional (2D) Airy beam in the visible region. The distinctive propagation characteristics of a vertically accelerated 2D Airy beam, including non-diffraction, self-acceleration, and self-healing, are experimentally demonstrated. An optical manipulation system equipped with a cubic-phase metasurface is designed to perform 3D manipulation of microscale particles. Due to the high-intensity gradients and the reciprocal propagation trajectory of Airy beams, particles can be laterally shifted and guided along the axial direction. In addition, the performance of optical trapping is quantitatively evaluated by experimentally measured trapping stiffness. Our metasurface has great potential to shape light for compact systems in the field of physics and biological applications.

Cubic Phase Metasurface for Three-Dimensional Optical Manipulation

2021 ◽  
Author(s):  
Hsin Yu Kuo ◽  
Hung-Chuan Hsu ◽  
Sunil Vyas ◽  
Cheng Hung Chu ◽  
Mu Ku Chen ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Optical Manipulation ◽  
Cubic Phase

scholarly journals Generation of One-Dimensional Terahertz Airy Beam by Three-Dimensional Printed Cubic-Phase Plate

2017 ◽  
Vol 9 (4) ◽  
pp. 1-7 ◽  
Author(s):  
Liting Niu ◽  
Changming Liu ◽  
Qiao Wu ◽  
Kejia Wang ◽  
Zhengang Yang ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Cubic Phase ◽  
Phase Plate ◽  
One Dimensional ◽  
Airy Beam

Airy beam for three-dimensional optical imaging

2017 ◽  
Author(s):  
◽  
Fengfei Wang
Keyword(s):  
Phase Space ◽  
Gaussian Beam ◽  
Phase Modulation ◽  
3D Imaging ◽  
Three Dimensional ◽  
Finite Energy ◽  
Main Lobe ◽  
Cubic Phase ◽  
Phase Pattern ◽  
Airy Beam

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Airy beam is a self-sustained light beam that propagates in free space along a parabolic trajectory with a constant lateral acceleration. It is a diffraction-free beam with an electric field pattern described by the Airy function containing a main lobe and side lobes. Unlike Gaussian beam that expands after the focus, a practical finite-energy Airy beam keeps its pattern without spreading over a relatively long distance during its propagation. This unique feature makes the Airy beam a great potential of designing optical systems for three-dimensional (3D) imaging. In this work, we develop a new optical 3D imaging methodology using Airy beam. The proposed imaging method has an advantage of increased depth of field (DOF) that is important in biological optical imaging. In the first step, we perform a fundamental research on specific parameters that can affect the properties of the Airy beams. The finite-energy Airy beams are generated by optical Fourier transform using a lens with the incoming plane wave that is truncated by an aperture. Our simulation and experiments showed that by changing the aperture size and the focal length of the lens, the Airy beam pattern is modified. In addition, the DOF, the beam size and the main lobe energy are changed. As a result, Airy beam can be designed for specific imaging applications. Next, we consider the phase in the cubic phase pattern for the phase modulation to generate the Airy beam. This problem is related to the wavelength dependent phase modulation since the phase in cubic phase pattern is designed for a specific wavelength whereas a broadband light source is normally used in optical coherence tomography (OCT). A liquid crystal display (LCD) panel from a projector is used as the SLM. The cubic phase patterns with different gray values displayed on the computer screen provide different phase modulations in the SLM. The experimental and simulated results show that the phase modulation affects the beam shape of the Airy beam. If the maximum phase modulation is larger than 1.7pi, the Airy beam can keep its pattern and the unmodulated Gaussian beam can be neglected. Further, we design a 3D imaging system using the phase-space method based on the Wigner distribution function (WDF). We theoretically build the WDF for the Airy beam and show that the WDF of the Airy beam is shifted in the phase-space as the transverse position of incoming Airy beam changes, and the WDF is tilted as changing the axial position (along the propagation direction). A larger truncating factor can reduce the energy contribution in WDF for the side lobes and modify the shape of the main lobe close to a straight line. In this case, the WDF of the Airy beam is similar to that of the Gaussian beam. However, the DOF of the Airy beam is greatly improved. We perform experimental measurements of WDF using the basic idea of measuring both the space and spatial frequency information in a 4-f system. Our experimental results match the simulation and validate the 3D imaging using Airy beam in the phase space.

Epithelial Organotypic Cultures: A Viable Model to Address Mechanisms of Carcinogenesis by Epitheliotropic Viruses

2018 ◽  
Vol 18 (4) ◽  
pp. 246-255 ◽  
Author(s):  
Lara Termini ◽  
Enrique Boccardo
Keyword(s):  
Three Dimensional ◽  
Cell Types ◽  
Experimental Models ◽  
Biological Research ◽  
Specific Gene ◽  
Specific Cell ◽  
Organotypic Cultures ◽  
Skin Physiology

In vitro culture of primary or established cell lines is one of the leading techniques in many areas of basic biological research. The use of pure or highly enriched cultures of specific cell types obtained from different tissues and genetics backgrounds has greatly contributed to our current understanding of normal and pathological cellular processes. Cells in culture are easily propagated generating an almost endless source of material for experimentation. Besides, they can be manipulated to achieve gene silencing, gene overexpression and genome editing turning possible the dissection of specific gene functions and signaling pathways. However, monolayer and suspension cultures of cells do not reproduce the cell type diversity, cell-cell contacts, cell-matrix interactions and differentiation pathways typical of the three-dimensional environment of tissues and organs from where they were originated. Therefore, different experimental animal models have been developed and applied to address these and other complex issues in vivo. However, these systems are costly and time consuming. Most importantly the use of animals in scientific research poses moral and ethical concerns facing a steadily increasing opposition from different sectors of the society. Therefore, there is an urgent need for the development of alternative in vitro experimental models that accurately reproduce the events observed in vivo to reduce the use of animals. Organotypic cultures combine the flexibility of traditional culture systems with the possibility of culturing different cell types in a 3D environment that reproduces both the structure and the physiology of the parental organ. Here we present a summarized description of the use of epithelial organotypic for the study of skin physiology, human papillomavirus biology and associated tumorigenesis.

scholarly journals Achromatic terahertz Airy beam generation with dielectric metasurfaces

Nanophotonics ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Qingqing Cheng ◽  
Juncheng Wang ◽  
Ling Ma ◽  
Zhixiong Shen ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Biomedical Imaging ◽  
Frequency Dispersion ◽  
Light Sheet ◽  
Photonic Devices ◽  
Self Healing ◽  
Beam Focusing ◽  
Light Sheet Microscopy ◽  
Airy Beam ◽  
Potential Applications ◽  
Airy Beams

AbstractAiry beams exhibit intriguing properties such as nonspreading, self-bending, and self-healing and have attracted considerable recent interest because of their many potential applications in photonics, such as to beam focusing, light-sheet microscopy, and biomedical imaging. However, previous approaches to generate Airy beams using photonic structures have suffered from severe chromatic problems arising from strong frequency dispersion of the scatterers. Here, we design and fabricate a metasurface composed of silicon posts for the frequency range 0.4–0.8 THz in transmission mode, and we experimentally demonstrate achromatic Airy beams exhibiting autofocusing properties. We further show numerically that a generated achromatic Airy-beam-based metalens exhibits self-healing properties that are immune to scattering by particles and that it also possesses a larger depth of focus than a traditional metalens. Our results pave the way to the realization of flat photonic devices for applications to noninvasive biomedical imaging and light-sheet microscopy, and we provide a numerical demonstration of a device protocol.

scholarly journals The first observation of 4D tomography measurement of plasma structures and fluctuations

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chanho Moon ◽  
Kotaro Yamasaki ◽  
Yoshihiko Nagashima ◽  
Shigeru Inagaki ◽  
Takeshi Ido ◽  
...  
Keyword(s):  
Steady State ◽  
Three Dimensional ◽  
Axial Direction ◽  
Axial Position ◽  
Entire Cross Section ◽  
Helicon Plasma ◽  
Emission Profile ◽  
Dimensional Measurement ◽  
Tomography System ◽  
Three Dimensional Measurement

AbstractA tomography system is installed as one of the diagnostics of new age to examine the three-dimensional characteristics of structure and dynamics including fluctuations of a linear magnetized helicon plasma. The system is composed of three sets of tomography components located at different axial positions. Each tomography component can measure the two-dimensional emission profile over the entire cross-section of plasma at different axial positions in a sufficient temporal scale to detect the fluctuations. The four-dimensional measurement including time and space successfully obtains the following three results that have never been found without three-dimensional measurement: (1) in the production phase, the plasma front propagates from the antenna toward the end plate with an ion acoustic velocity. (2) In the steady state, the plasma emission profile is inhomogeneous, and decreases along the axial direction in the presence of the azimuthal asymmetry. Furthermore, (3) in the steady state, the fluctuations should originate from a particular axial position located downward from the helicon antenna.

Revealing a metastable cubic phase in CoFe2O4–SrTiO3 three-dimensional network heteroepitaxial nanostructure

2020 ◽  
Vol 128 (22) ◽  
pp. 225303
Author(s):  
Haili Song ◽  
Chao Li ◽  
Chih-Kuo Wang ◽  
Jan-Chi Yang ◽  
Jianjun Lin ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Cubic Phase ◽  
Dimensional Network

A Self‐Healing Volume Variation Three‐Dimensional Continuous Bulk Porous Bismuth for Ultrafast Sodium Storage

2021 ◽  
pp. 2011264
Author(s):  
Xiaolong Cheng ◽  
Ruiwen Shao ◽  
Dongjun Li ◽  
Hai Yang ◽  
Ying Wu ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Self Healing ◽  
Volume Variation ◽  
Sodium Storage

Macromolecular Structure Visualization Tools at NCMI

2000 ◽  
Vol 6 (S2) ◽  
pp. 282-283
Author(s):  
Matthew Dougherty ◽  
Wah Chiu
Keyword(s):  
Human Factors ◽  
3D Visualization ◽  
Three Dimensional ◽  
Theoretical Models ◽  
Biological Research ◽  
Macromolecular Structure ◽  
X Ray ◽  
Visualization Tools ◽  
Types Of Information ◽  
3D Em

Sophisticated tools are needed to examine the results of cyro-microscopy. As the size and resolution of three dimensional macromolecular structures steadily improve, and the speed at with which they can be generated increases, researchers are finding they are inundated with larger datasets and at the same time are compelled to expediently evaluate these structures in unforeseen ways. Integration of EM data with other types of information is becoming necessary and routine; for example X-ray data, 3D EM reconstructions, and theoretical models, must be evaluated in concert to discount or propose hypothesis. To create such tools, the developer must take into account not only the empirical and theoretical possibilities, but also they must master the human factors and computational limits. During the last five years, the National Center for Macromolecular Imaging (NCMI) has progressed from a remedial 3D visualization capability to a collection of visualization tools allowing researchers to focus on the discovery phase of biological research.

Free Vibrations of Thick, Complete Conical Shells of Revolution From a Three-Dimensional Theory

2005 ◽  
Vol 72 (5) ◽  
pp. 797-800 ◽  
Author(s):  
Jae-Hoon Kang ◽  
Arthur W. Leissa
Keyword(s):  
Ritz Method ◽  
Three Dimensional ◽  
Axial Direction ◽  
Free Vibrations ◽  
Mode Shapes ◽  
Vibration Frequencies ◽  
Shells Of Revolution ◽  
Dimensional Theory ◽  
Conical Shells ◽  
Cylindrical Coordinate

A three-dimensional (3D) method of analysis is presented for determining the free vibration frequencies and mode shapes of thick, complete (not truncated) conical shells of revolution in which the bottom edges are normal to the midsurface of the shells based upon the circular cylindrical coordinate system using the Ritz method. Comparisons are made between the frequencies and the corresponding mode shapes of the conical shells from the authors' former analysis with bottom edges parallel to the axial direction and the present analysis with the edges normal to shell midsurfaces.

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