scholarly journals Role of Hydrogen Peroxide Vapor (HPV) for the Disinfection of Hospital Surfaces Contaminated by Multiresistant Bacteria

Pathogens ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 408
Author(s):  
Michele Totaro ◽  
Beatrice Casini ◽  
Sara Profeti ◽  
Benedetta Tuvo ◽  
Gaetano Privitera ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Preventive Measures ◽  
Critical Role ◽  
Bacterial Strains ◽  
Clinical Practices ◽  
Environmental Cleaning ◽  
Control Techniques ◽  
Multiresistant Bacteria ◽  
Hydrogen Peroxide Vapor

The emergence of multiresistant bacterial strains as agents of healthcare-related infection in hospitals has prompted a review of the control techniques, with an added emphasis on preventive measures, namely good clinical practices, antimicrobial stewardship, and appropriate environmental cleaning. The latter item is about the choice of an appropriate disinfectant as a critical role due to the difficulties often encountered in obtaining a complete eradication of environmental contaminations and reservoirs of pathogens. The present review is focused on the effectiveness of hydrogen peroxide vapor, among the new environmental disinfectants that have been adopted. The method is based on a critical review of the available literature on this topic

scholarly journals How to Be Savvy About Gender Disparities in Academic Stroke Medicine

Stroke ◽  
2020 ◽  
Vol 51 (9) ◽  
Author(s):  
Aleksandra Pikula ◽  
Luciana Catanese ◽  
Cheryl D. Bushnell ◽  
Valeria Caso ◽  
Julie K. Silver
Keyword(s):  
Clinical Care ◽  
Critical Role ◽  
Women's Leadership ◽  
Gender Disparities ◽  
Early Career ◽  
Diagnostic Tools ◽  
Career Stage ◽  
Clinical Practices ◽  
New Treatments

In the past decade, stroke medicine has evolved from discovery of innovative diagnostic tools to implementation of new treatments. These advances are projected to increase the demand for stroke neurologists in academic and clinical practices, but hopefully with equitable opportunities for everyone across the gender spectrum. Academic medicine provides opportunities to participate in clinical care, teaching, research, and administration. The early career stage is short-focused on finding an academic niche and developing new skills that will help you navigate the academic environment. A recent InterSECT article emphasized the critical role of women’s leadership in stroke medicine. In this article, we reflect on workforce gender disparities and provide 5 practical strategies that may help women overcome barriers and advance their work mission.

The Critical Role of Hepes in SIN-1 Cytotoxicity, Peroxynitrite Versus Hydrogen Peroxide

1998 ◽  
Vol 24 (4) ◽  
pp. 522-528 ◽  
Author(s):  
Elena E Lomonosova ◽  
Michael Kirsch ◽  
Ursula Rauen ◽  
Herbert de Groot
Keyword(s):  
Hydrogen Peroxide ◽  
Critical Role

scholarly journals Role of Information Technology in COVID19 Vaccination Drive: An Analysis of the COVID-19 Global Beliefs, Behaviors, and Norms Survey

2021 ◽  
Author(s):  
Debjyoti Talukdar ◽  
Kire Stojkovski ◽  
Daniel Suarez
Keyword(s):  
Information Technology ◽  
Social Norms ◽  
Essential Role ◽  
Preventive Measures ◽  
Critical Role ◽  
Vaccine Acceptance ◽  
Factors Associated ◽  
Diverse Communities ◽  
Role Of Information

With the onset of the COVID19 pandemic, information technology has played a critical role in healthcare. A broad spectrum of information technology tools and applications played an essential role to create awareness of the COVID19 vaccination drive and its health benefits. We use the COVID-19 Global Beliefs, Behaviors, and Norms Survey for analysis of prevalence and factors associated with vaccination drives among men and women aged 20-80 years in 60 countries worldwide. Our analysis of the global survey offers a unique perspective about the role of information technology associated with vaccination drives involving social norms and human behavior among 437,236 respondents. The international survey was organized using a pre-registered randomized experiment demonstrating the role of technology in reaching out to people based in diverse communities and evaluating their beliefs, behavior, and social norms. The study shows that vaccine acceptance can vary due to descriptive norms. Our analysis shows 65.06% of people all over the globe are willing to get vaccinated and a large proportion of the population thinks that the COVID19 pandemic is a viable threat to the community and preventive measures need to be taken including vaccination drives.

scholarly journals Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis

2020 ◽  
Vol 5 (53) ◽  
pp. eabc7191
Author(s):  
Anne-Katrin Pröbstel ◽  
Xiaoyuan Zhou ◽  
Ryan Baumann ◽  
Sven Wischnewski ◽  
Michael Kutza ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
B Cells ◽  
Gut Microbiota ◽  
Critical Role ◽  
Immunoglobulin A ◽  
Therapeutic Interventions ◽  
Bacterial Strains ◽  
Gut Microbiota Composition ◽  
Active Multiple Sclerosis

Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a central nervous system (CNS) autoimmune disease. Immunoglobulin A (IgA) is a key regulator at the mucosal interface. However, whether gut microbiota shape IgA responses and what role IgA+ cells have in neuroinflammation are unknown. Here, we identify IgA-bound taxa in MS and show that IgA-producing cells specific for MS-associated taxa traffic to the inflamed CNS, resulting in a strong, compartmentalized IgA enrichment in active MS and other neuroinflammatory diseases. Unlike previously characterized polyreactive anti-commensal IgA responses, CNS IgA cross-reacts with surface structures on specific bacterial strains but not with brain tissue. These findings establish gut microbiota–specific IgA+ cells as a systemic mediator in MS and suggest a critical role of mucosal B cells during active neuroinflammation with broad implications for IgA as an informative biomarker and IgA-producing cells as an immune subset to harness for therapeutic interventions.

scholarly journals Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: critical role of hemeoxygenase-1 and NQO1 expression

2011 ◽  
Vol 119 (5) ◽  
pp. 909-919 ◽  
Author(s):  
Jin-Sun Park ◽  
Ji-Sun Jung ◽  
Yeon-Hui Jeong ◽  
Jin-Won Hyun ◽  
Thi Kim Van Le ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Critical Role ◽  
Antioxidant Mechanism ◽  
Primary Astrocytes

scholarly journals Critical Role of Endothelial Hydrogen Peroxide in Post-Ischemic Neovascularization

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e57618 ◽  
Author(s):  
Norifumi Urao ◽  
Varadarajan Sudhahar ◽  
Seok-Jo Kim ◽  
Gin-Fu Chen ◽  
Ronald D. McKinney ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Critical Role

Critical role of hydrogen peroxide signaling in the sequential activation of p38 MAPK and eNOS in laminar shear stress

2012 ◽  
Vol 52 (6) ◽  
pp. 1093-1100 ◽  
Author(s):  
Rosa Bretón-Romero ◽  
Cecilia González de Orduña ◽  
Natalia Romero ◽  
Francisco J. Sánchez-Gómez ◽  
Cristina de Álvaro ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Shear Stress ◽  
P38 Mapk ◽  
Critical Role ◽  
Laminar Shear Stress ◽  
Sequential Activation ◽  
Laminar Shear

scholarly journals A Critical Role of TRPM2 in Neuronal Cell Death by Hydrogen Peroxide

2006 ◽  
Vol 101 (1) ◽  
pp. 66-76 ◽  
Author(s):  
Shuji Kaneko ◽  
Seiko Kawakami ◽  
Yuji Hara ◽  
Minoru Wakamori ◽  
Etsuko Itoh ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Cell Death ◽  
Critical Role ◽  
Neuronal Cell Death ◽  
Neuronal Cell

Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis

2008 ◽  
Vol 75 (2) ◽  
pp. 552-561 ◽  
Author(s):  
Saeko Tada-Oikawa ◽  
Takuma Kato ◽  
Kagemasa Kuribayashi ◽  
Kohsuke Nishino ◽  
Mariko Murata ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Critical Role ◽  
Differential Susceptibility ◽  
Th2 Cells ◽  
Induced Apoptosis ◽  
Th1 And Th2
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