scholarly journals Soothing Properties of Glycerol in Cough Syrups for Acute Cough Due to Common Cold

Pharmacy ◽  
2017 ◽  
Vol 5 (4) ◽  
pp. 4 ◽  
Author(s):  
Ronald Eccles ◽  
Pascal Mallefet
Keyword(s):  
2011 ◽  
Vol 51 (2) ◽  
pp. 111
Author(s):  
Yenny Yenny ◽  
Roni Naning ◽  
Amalia Setyati

Background T h e prevalence of the common cold in children is high, v.ith 30% of cases exhibiting an acute cough, the most common complaint by parents. Erdosteine, a recently developed cough medicine, is available for children. Erdosteine has been reported to increase mucodliary clearance, act as an antioxidant and prevent bacterial adhesion.Objective To assess the clinical improvement in acute cough in children \\lith a common cold taking erdosteine vs. a placebo.Methods We conducted a double􀀾blind, randomized, controlled trial at the Public Health Center of Gedongtengen, Yogyakarta with 140 children selected by a consecutive sampling method. Research subjects were randomized by computer program into two treatment groups, those receiving erdosteine therapy and those receiving a placebo. Both groups were monitored for 6 days. A scoring system was used to assess the improvement of acute cough symptoms and analyzed by Chi-square test.Results No significant differences in basic characteristics, cough severity, or environment were found among the 140 children with common cold in the two groups. After 6 days of treatment, no significant difference in clinical improvement of acute cough was found between the erdosteine (65 subjects improved out of 70) and placebo groups (62/70),92.5% and 88.6%, respectively (P=0.382).Conclusion Erdosteine was not more effective than the placebo for treatment of acute cough in children with common cold.


Antibiotics ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 163 ◽  
Author(s):  
Li Shi ◽  
Jie Chang ◽  
Xiaoxi Liu ◽  
Panpan Zhai ◽  
Shuchen Hu ◽  
...  

The inappropriate use of antibiotics is a major health issue in China. We aimed to assess nonprescription antibiotic dispensing and assess pharmacy service practice at community pharmacies in Shenyang, northeastern China, and to compare these practices between pediatric and adult cases. A cross-sectional study was performed from March to May 2018 using the standardized client method. Two different simulated scenarios were presented at pharmacies, namely, pediatric and adult acute cough associated with a common cold. Of 150 pharmacy visits, 147 visits were completed (pediatric case: 73, adult case: 74). A total of 130 (88.4%) community pharmacies dispensed antibiotics without a prescription, with a significant difference between pediatric and adult cases (pediatric case, 79.5% versus adult case, 97.3%, p = 0.005). Symptoms were asked in most visits (pediatric case: 82.2%, adult case 82.4%). Patients’ previous treatment and history of allergies were both inquired more frequently in the pediatric cases than in the adult cases. Medication advice was provided more often in the adult cases than in pediatric cases. Antibiotics were easily obtained without a prescription in Shenyang, especially for adult patients. Adequate inquiries and counseling had not occurred in most pharmacies.


CHEST Journal ◽  
2017 ◽  
Vol 152 (5) ◽  
pp. 1021-1037 ◽  
Author(s):  
Mark A. Malesker ◽  
Priscilla Callahan-Lyon ◽  
Belinda Ireland ◽  
Richard S. Irwin ◽  
Todd M. Adams ◽  
...  

2021 ◽  
Author(s):  
Siyuan Hu ◽  
Qiuhan CAI ◽  
Xinmin LI ◽  
Chengliang ZHONG ◽  
Youpeng WANG ◽  
...  

Abstract Background: Cough is the most bothersome symptom, while more than two-thirds of children with common cold have to endure it for weeks. Susu xiao`er zhike granules (Susu) which used to be a clinical experienced herb formula for treating cough caused by common cold, is reproduced into a patent medicine for meeting market demands as a new drug. This protocol is designed with the aim of exploring the efficacy of Susu on shortening duration and reducing severity of cough, and observe the safety used in children. Methods/design: This is a protocol for a randomized, double-blind, dose exploration, multicenter clinical trial. A total of 240 children aged 6-14 years old (<14y) with acute cough caused by common cold will be randomly assigned to one of three groups, respectively take Susu of high dose (double-dose), medium dose (recommended dose) and very low dose (5% recommended dose) for 5 days. The primary outcome is clinical cure time of cough. Secondary outcomes will include clinical cure rate, onset time, AUC of cough severity VAS score-time, PAC-QoL, PGA, cure rate of symptoms and efficacy of traditional Chinese syndrome. For safety assessment, adverse events, laboratory tests and vital signs will be observed. Participants will complete the trial after 1-day follow up assessment. We collect the main data from subject diary. Discussion: The study is a phase II clinical trial that will evaluate the efficacy of a Chinese patent medicine in the treatment of cough in children.Trial registration: Chinese clinical trial registry, ChiCTR1900028377. Registered 20 December 2019, http://www.chictr.org.cn/showproj.aspx?proj=46643


2021 ◽  
Vol 1 ◽  
Author(s):  
Tobias Mueck

Two randomised, blind, controlled, multicentre studies investigated the therapeutic effect of a chemical and mechanical barrier in the upper airways produced by polysaccharide-resin-honey based cough syrup in children with acute cough associated with a common cold. The mucoprotection led to a significant alleviation of the paediatric cough compared with carbocysteine syrup or placebo. The beneficial effect was especially apparent in children with severe cough and/or episodes of nocturnal coughing.


Author(s):  
Ghotekar D S ◽  
Vishal N Kushare ◽  
Sagar V Ghotekar

Coronaviruses are a family of viruses that cause illness such as respiratory diseases or gastrointestinal diseases. Respiratory diseases can range from the common cold to more severe diseases. A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019. The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) a pandemic. A global coordinated effort is needed to stop the further spread of the virus. A novel coronavirus (nCoV) is a new strain that has not been identified in humans previously. Once scientists determine exactly what coronavirus it is, they give it a name (as in the case of COVID-19, the virus causing it is SARS-CoV-2).


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1026-1033
Author(s):  
Nivedha Valliammai Mahalingam ◽  
Abilasha R ◽  
Kavitha S

Enormous successes have been obtained against the control of major epidemic diseases, such as SARS, MERS, Ebola, Swine Flu in the past. Dynamic interplay of biological, socio-cultural and ecological factors, together with novel aspects of human-animal interphase, pose additional challenges with respect to the emergence of infectious diseases. The important challenges faced in the control and prevention of emerging and re-emerging infectious diseases range from understanding the impact of factors that are necessary for the emergence, to development of strengthened surveillance systems that can mitigate human suffering and death. The aim of the current study is to assess the awareness of symptomatic differences between viral diseases like COVID-19, SARS, Swine flu and common cold among dental students that support the prevention of emergence or re-emergence. Cross-sectional type of study conducted among the undergraduate students comprising 100 Subjects. A questionnaire comprising 15 questions in total were framed, and responses were collected in Google forms in SPSS Software statistical analysis. The study has concluded that dental students have an awareness of the symptomatic differences between infectious viral disease. The study concluded that the awareness of symptomatic differences between viral diseases like COVID-19, SARS, Swine flu, Common cold is good among the dental students who would pave the way for early diagnosis and avoid spreading of such diseases. A further awareness can be created by regular webinars, seminars and brainstorming sessions among these healthcare professionals.


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