scholarly journals Influence of Fluid Properties on Intensity of Hydrodynamic Cavitation and Deactivation of Salmonella typhimurium

Processes ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 326 ◽  
Author(s):  
Moein Talebian Gevari ◽  
Ayhan Parlar ◽  
Milad Torabfam ◽  
Ali Koşar ◽  
Meral Yüce ◽  
...  

In this study, three microfluidic devices with different geometries are fabricated on silicon and are bonded to glass to withstand high-pressure fluid flows in order to observe bacteria deactivation effects of micro cavitating flows. The general geometry of the devices was a micro orifice with macroscopic wall roughness elements. The width of the microchannel and geometry of the roughness elements were varied in the devices. First, the thermophysical property effect (with deionized water and phosphate-buffered saline (PBS)) on flow behavior was revealed. The results showed a better performance of the device in terms of cavitation generation and intensity with PBS due to its higher density, higher saturation vapor pressure, and lower surface tension in comparison with water. Moreover, the second and third microfluidic devices were tested with water and Salmonella typhimurium bacteria suspension in PBS. Accordingly, the presence of the bacteria intensified cavitating flows. As a result, both devices performed better in terms of the intensity of cavitating flow with the presence of bacteria. Finally, the deactivation performance was assessed. A decrease in the bacteria colonies on the agar plate was detected upon the tenth cycle of cavitating flows, while a complete deactivation was achieved after the fifteenth cycle. Thus, the proposed devices can be considered as reliable hydrodynamic cavitation reactors for “water treatment on chip” applications.

Micromachines ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 49 ◽  
Author(s):  
Moein Talebian Gevari ◽  
Ali Hosseinpour Shafaghi ◽  
Luis Guillermo Villanueva ◽  
Morteza Ghorbani ◽  
Ali Koşar

Hydrodynamic cavitation is considered an effective tool to be used in different applications, such as surface cleaning, ones in the food industry, energy harvesting, water treatment, biomedical applications, and heat transfer enhancement. Thus, both characterization and intensification of cavitation phenomenon are of great importance. This study involves design and optimization of cavitation on chip devices by utilizing wall roughness elements and working fluid alteration. Seven different microfluidic devices were fabricated and tested. In order to harvest more energy from cavitating flows, different roughness elements were used to decrease the inlet pressure (input to the system), at which cavitation inception occurs. The implemented wall roughness elements were engineered structures in the shape of equilateral triangles embedded in the design of the microfluidic devices. The cavitation phenomena were also studied using ethanol as the working fluid, so that the fluid behavior differences in the tested cavitation on chip devices were explained and compared. The employment of the wall roughness elements was an effective approach to optimize the performances of the devices. The experimental results exhibited entirely different flow patterns for ethanol compared to water, which suggests the dominant effect of the surface tension on hydrodynamic cavitation in microfluidic channels.


2019 ◽  
Vol 28 (5) ◽  
pp. 890-899 ◽  
Author(s):  
Morteza Ghorbani ◽  
Gokberk Deprem ◽  
Ece Ozdemir ◽  
Ahmad Reza Motezakker ◽  
L. Guillermo Villanueva ◽  
...  

2016 ◽  
Vol 136 (6) ◽  
pp. 244-249
Author(s):  
Takahiro Watanabe ◽  
Fumihiro Sassa ◽  
Yoshitaka Yoshizumi ◽  
Hiroaki Suzuki

Author(s):  
Jing Ren ◽  
Sriram Sundararajan

Realistic random roughness of channel surfaces is known to affect the fluid flow behavior in microscale fluidic devices. This has relevance particularly for applications involving non-Newtonian fluids, such as biomedical lab-on-chip devices. In this study, a surface texturing process was developed and integrated into microfluidic channel fabrication. The process combines colloidal masking and Reactive Ion Etching (RIE) for generating random surfaces with desired roughness parameters on the micro/nanoscale. The surface texturing process was shown to be able to tailor the random surface roughness on quartz. A Large range of particle coverage (around 6% to 67%) was achieved using dip coating and drop casting methods using a polystyrene colloidal solution. A relation between the amplitude roughness, autocorrelation length, etch depth and particle coverage of the processed surface was built. Experimental results agreed reasonably well with model predictions. The processed substrate was further incorporated into microchannel fabrication. Final device with designed wall roughness was tested and proved a satisfying sealing performance.


Lab on a Chip ◽  
2021 ◽  
Author(s):  
Wei Zhang ◽  
Bin Song ◽  
Xue Bai ◽  
Lina Jia ◽  
Li Song ◽  
...  

Controllable on-chip multimodal manipulation of micro-objects in microfluidic devices is urgently required for enhancing the efficiency of potential biomedical applications. However, fixed design and driving models make it difficult to...


Author(s):  
Reinaldo Lucas dos Santos Rosa ◽  
Antonio Carlos Seabra

This chapter provides a guide for microfluidic devices development and optimization focused on chemical analysis applications, which includes medicine, biology, chemistry, and environmental monitoring, showing high-level performance associated with a specific functionality. Examples are chemical analysis, solid phase extraction, chromatography, immunoassay analysis, protein and DNA separation, cell sorting and manipulation, cellular biology, and mass spectrometry. In this chapter, most information is related to microfluidic devices design and fabrication used to perform several steps concerning chemical analysis, process preparation of reagents, samples reaction and detection, regarding water quality monitoring. These steps are especially relevant to lab-on-chip (LOC) and micro-total-analysis-systems (μTAS). μTAS devices are developed in order to simplify analytical chemist work, incorporating several analytical procedures into flow systems. In the case of miniaturized devices, the analysis time is reduced, and small volumes (nL) can be used.


Lab on a Chip ◽  
2018 ◽  
Vol 18 (1) ◽  
pp. 162-170 ◽  
Author(s):  
Kadi L. Saar ◽  
Yingbo Zhang ◽  
Thomas Müller ◽  
Challa P. Kumar ◽  
Sean Devenish ◽  
...  

Single-layer lithography microfluidic devices for applying high and stable electric fields on chip.


Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 85 ◽  
Author(s):  
Brigitte Bruijns ◽  
Andrea Veciana ◽  
Roald Tiggelaar ◽  
Han Gardeniers

Microfluidic devices offer important benefits for forensic applications, in particular for fast tests at a crime scene. A large portion of forensic applications require microfluidic chip material to show compatibility with biochemical reactions (such as amplification reactions), and to have high transparency in the visible region and high chemical resistance. Also, preferably, manufacturing should be simple. The characteristic properties of cyclic olefin copolymer (COC) fulfills these requirements and offers new opportunities for the development of new forensic tests. In this work, the versatility of COC as material for lab-on-a-chip (LOC) systems in forensic applications has been explored by realizing two proof-of-principle devices. Chemical resistance and optical transparency were investigated for the development of an on-chip presumptive color test to indicate the presence of an illicit substance through applying absorption spectroscopy. Furthermore, the compatibility of COC with a DNA amplification reaction was verified by performing an on-chip multiple displacement amplification (MDA) reaction.


2020 ◽  
Vol 30 (2) ◽  
pp. 025005
Author(s):  
Teng Shen ◽  
Zhanggen Zhu ◽  
Liu Huang ◽  
Jiaqing Chang

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