scholarly journals Highly Responsive and Ultrasensitive Non-Enzymatic Electrochemical Glucose Sensor Based on Au Foam

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1203 ◽  
Author(s):  
Nannan Shen ◽  
Haijun Xu ◽  
Weichen Zhao ◽  
Yongmei Zhao ◽  
Xin Zhang
Keyword(s):  
High Selectivity ◽  
Glucose Sensor ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Au Nanoparticle ◽  
Quantitative Detection ◽  
Term Stability ◽  
Long Term Stability ◽  
Surface Enhanced Raman

Glucose concentration is an important physiological index, therefore methods for sensitive detection of glucose are important. In this study, Au foam was prepared by electrodeposition with a dynamic gas template on an Au nanoparticle/Si substrate. The Au foam showed ultrasensitivity, high selectivity, and long-term stability in the quantitative detection of glucose. The foam was used as an electrode, and the amperometric response indicated excellent catalytic activity in glucose oxidation, with a linear response across the concentration range 0.5 μM to 12 mM, and a limit of detection of 0.14 μM. High selectivity for interfering molecules at six times the normal level and long-term stability for 30 days were obtained. The results for electrochemical detection with Au foam of glucose in human serum were consistent with those obtained with a sensor based on surface-enhanced Raman spectroscopy and a commercial sensor. This proves that this method can be used with real samples. These results show that Au foam has great potential for use as a non-enzymatic glucose sensor.

scholarly journals Designing organic solvent separation membranes: Polymers, porous structures, 2D materials, and their combinations

2021 ◽  
Author(s):  
Ameya Manoj Tandel ◽  
Wenji Guo ◽  
Kelly Bye ◽  
Liang Huang ◽  
Michele Galizia ◽  
...  
Keyword(s):  
Organic Solvent ◽  
High Selectivity ◽  
2D Materials ◽  
Porous Structures ◽  
Membrane Materials ◽  
Term Stability ◽  
Long Term Stability ◽  
Separation Membranes ◽  
Tremendous Progress

As interest for membrane-based organic solvent separation increases, membrane materials exhibiting high permeance, high selectivity, and long-term stability against solvents are sought. Membrane technology has experienced tremendous progress by integrating...

A long-term stable paper-based glucose sensor using a glucose oxidase-loaded, Mn2BPMP-conjugated nanocarrier with a smartphone readout

Nanoscale ◽  
2021 ◽  
Author(s):  
Soyeon Yoo ◽  
Kiyoon Min ◽  
Giyoong Tae ◽  
Min Su Han
Keyword(s):  
Glucose Oxidase ◽  
Glucose Sensor ◽  
Sensor System ◽  
Term Stability ◽  
Long Term Stability

A paper-type sensor system was devised using an enzyme-loaded, artificial peroxidase-conjugated nanocarrier to maintain long-term stability with smartphone readout.

Stability and Surface Uniformity of Selected Thiol-Coated SERS Surfaces

1997 ◽  
Vol 51 (9) ◽  
pp. 1355-1359 ◽  
Author(s):  
Timothy O. Deschaines ◽  
Keith T. Carron
Keyword(s):  
Spatial Heterogeneity ◽  
Sodium Dodecylsulfate ◽  
Surface Wetting ◽  
Thiol Compounds ◽  
Analytical Technique ◽  
Term Stability ◽  
Long Term Stability ◽  
Surface Enhanced Raman ◽  
Coated Surfaces

The use of surface-enhanced Raman scattering (SERS) as an analytical technique continues to grow, but questions about its viability remain. This paper addresses the concern about the long-term stability of the surfaces used with the SERS technique. We have studied the long-term stability of Ag surfaces coated with three different thiol compounds. For this study, we have used 1-propanethiol, 1-do-decanethiol, and p-cresolthiol to coat the Ag surfaces. These surfaces showed long-term stabilities of over a month with minimal surface degradation. In order to mimic a realistic application of SERS, we stored the coated surfaces in a solution of water. Sodium dodecylsulfate (SDS) was added to maintain consistent surface wetting conditions so that reproducible results were obtainable on a day-to-day basis. Spatial heterogeneity of the surfaces and coating was analyzed with a fiber-optic Raman system. The spatial heterogeneity of the surfaces explains the day-to-day variations observed in the detection when the same portion of the surface used for analysis varies from day to day.

scholarly journals A Miniaturised, Fully Integrated NDIR CO2 Sensor On-Chip

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5347
Author(s):  
Xiaoning Jia ◽  
Joris Roels ◽  
Roel Baets ◽  
Gunther Roelkens
Keyword(s):  
Water Vapor ◽  
Limit Of Detection ◽  
Wafer Level ◽  
Water Vapor Absorption ◽  
Optical Source ◽  
Fully Integrated ◽  
Term Stability ◽  
Long Term Stability ◽  
Co2 Sensor

In this paper, we present a fully integrated Non-dispersive Infrared (NDIR) CO2 sensor implemented on a silicon chip. The sensor is based on an integrating cylinder with access waveguides. A mid-IR LED is used as the optical source, and two mid-IR photodiodes are used as detectors. The fully integrated sensor is formed by wafer bonding of two silicon substrates. The fabricated sensor was evaluated by performing a CO2 concentration measurement, showing a limit of detection of ∼750 ppm. The cross-sensitivity of the sensor to water vapor was studied both experimentally and numerically. No notable water interference was observed in the experimental characterizations. Numerical simulations showed that the transmission change induced by water vapor absorption is much smaller than the detection limit of the sensor. A qualitative analysis on the long term stability of the sensor revealed that the long term stability of the sensor is subject to the temperature fluctuations in the laboratory. The use of relatively cheap LED and photodiodes bare chips, together with the wafer-level fabrication process of the sensor provides the potential for a low cost, highly miniaturized NDIR CO2 sensor.

Preparation of Glucose Sensor Using Polydimethylsiloxane / Polypyrrole Complex

2003 ◽  
Vol 17 (08n09) ◽  
pp. 1217-1222 ◽  
Author(s):  
Mikito Yasuzawa ◽  
Shigeru Inoue ◽  
Shinji Imai
Keyword(s):  
Glucose Sensor ◽  
Platelet Rich Plasma ◽  
Glucose Sensors ◽  
Wire Electrode ◽  
Term Stability ◽  
Long Term Stability ◽  
Response Current ◽  
And Storage ◽  
Storage Temperatures

New glucose oxidase (GOD) immobilized glucose sensors were prepared by the electropolymerization of 1-(6-D-gluconamidohexyl) pyrrole (GHP) on the platinum wire electrode precoated with the mixture solution of pyrrole derivative GHP, polydimethylsiloxane (PDS) and Nafion. The addition of Nafion into the precoating mixture solution was essential to obtain suitable sensor sensitivity. However, the sensitivity was about the half of that of the electrode without PDS precoating. Although, the introduction of Nafion was effective to improve the long-term stability of the enzyme-immobilized electrode, the electrode prepared using Nafion, PDS and GHP performed excellent long-term stability even at the measurement and storage temperatures of 40°C. Relatively constant response current was obtained over 30 days under the condition of 40°C and over 9 months measured at 25°C. Moreover, the GOD-immobilized GHP polymer film prepared on the electrode precoated with GHP, PDS and Nafion solution, was found to have excellent hemocompatibility from the result of platelet rich plasma contacting test.

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