Improvement in the Long-Term Stability of an Amperometric Glucose Sensor System by Introducing a Cellulose Membrane of Bacterial Origin

1995 ◽  
Vol 67 (2) ◽  
pp. 466-471 ◽  
Author(s):  
H. P. T. Ammon ◽  
W. Ege ◽  
M. Oppermann ◽  
W. Goepel ◽  
S. Eisele
Nanoscale ◽  
2021 ◽  
Author(s):  
Soyeon Yoo ◽  
Kiyoon Min ◽  
Giyoong Tae ◽  
Min Su Han

A paper-type sensor system was devised using an enzyme-loaded, artificial peroxidase-conjugated nanocarrier to maintain long-term stability with smartphone readout.


Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1203 ◽  
Author(s):  
Nannan Shen ◽  
Haijun Xu ◽  
Weichen Zhao ◽  
Yongmei Zhao ◽  
Xin Zhang

Glucose concentration is an important physiological index, therefore methods for sensitive detection of glucose are important. In this study, Au foam was prepared by electrodeposition with a dynamic gas template on an Au nanoparticle/Si substrate. The Au foam showed ultrasensitivity, high selectivity, and long-term stability in the quantitative detection of glucose. The foam was used as an electrode, and the amperometric response indicated excellent catalytic activity in glucose oxidation, with a linear response across the concentration range 0.5 μM to 12 mM, and a limit of detection of 0.14 μM. High selectivity for interfering molecules at six times the normal level and long-term stability for 30 days were obtained. The results for electrochemical detection with Au foam of glucose in human serum were consistent with those obtained with a sensor based on surface-enhanced Raman spectroscopy and a commercial sensor. This proves that this method can be used with real samples. These results show that Au foam has great potential for use as a non-enzymatic glucose sensor.


2003 ◽  
Vol 17 (08n09) ◽  
pp. 1217-1222 ◽  
Author(s):  
Mikito Yasuzawa ◽  
Shigeru Inoue ◽  
Shinji Imai

New glucose oxidase (GOD) immobilized glucose sensors were prepared by the electropolymerization of 1-(6-D-gluconamidohexyl) pyrrole (GHP) on the platinum wire electrode precoated with the mixture solution of pyrrole derivative GHP, polydimethylsiloxane (PDS) and Nafion. The addition of Nafion into the precoating mixture solution was essential to obtain suitable sensor sensitivity. However, the sensitivity was about the half of that of the electrode without PDS precoating. Although, the introduction of Nafion was effective to improve the long-term stability of the enzyme-immobilized electrode, the electrode prepared using Nafion, PDS and GHP performed excellent long-term stability even at the measurement and storage temperatures of 40°C. Relatively constant response current was obtained over 30 days under the condition of 40°C and over 9 months measured at 25°C. Moreover, the GOD-immobilized GHP polymer film prepared on the electrode precoated with GHP, PDS and Nafion solution, was found to have excellent hemocompatibility from the result of platelet rich plasma contacting test.


2013 ◽  
Vol 669 ◽  
pp. 325-330
Author(s):  
Yaoen Yang ◽  
Xing Cheng Sun ◽  
Qing Min Wang

The conventional sensor in bridge structure vibration monitoring field has such disadvantages as high price and poor long-term stability. According to this insufficient, a kind of novel MEMS sensor micro system, which can be used to real-time monitor the structure vibration of large span bridge, is developed. For such system, the sensing element structure of 3D-MEMS is designed. The theoretical model of sensing test is established. And the three level packages, which are chip level, device level and micro-system level, is completed. The data acquisition system based on this sensor is developed. And this kind of sensor system has been applied to the structure health monitoring of the Yellow River bridge of Zhengzhou and the Yangtze River bridge of Wuhan to measure the horizontal, vertical vibration and acceleration signals. The measuring results show that this sensor micro-system has such advantages as good long-term stability, strong anti-interference ability, and high test sensitivity up to 2V/g. As it is simple, this test system can greatly reduce the testing cost.


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