Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration
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We present fluorescent Janus hydrogel microbeads for continuous glucose sensing with pH calibration. The Janus hydrogel microbeads, that consist of fluorescent glucose and pH sensors, were fabricated with a UV-assisted centrifugal microfluidic device. The microbead can calibrate the pH values of its surroundings and enables accurate measurements of glucose within various pH conditions. As a proof of concept, we succeeded in obtaining the accurate value of glucose concentration in a body-fluid-like sample solution. We believe that our fluorescent microbeads, with pH calibration capability, could be applied to fully implantable sensors for continuous glucose monitoring.
2021 ◽
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2003 ◽
Vol 5
(2)
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pp. 159-166
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2018 ◽
Vol 15
(3)
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pp. 175-184
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1992 ◽
Vol 55
(11)
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pp. 893-898
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