scholarly journals Bluetongue Virus in France: An Illustration of the European and Mediterranean Context since the 2000s

Viruses ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 672 ◽  
Author(s):  
Cindy Kundlacz ◽  
Grégory Caignard ◽  
Corinne Sailleau ◽  
Cyril Viarouge ◽  
Lydie Postic ◽  
...  

Bluetongue (BT) is a non-contagious animal disease transmitted by midges of the Culicoides genus. The etiological agent is the BT virus (BTV) that induces a variety of clinical signs in wild or domestic ruminants. BT is included in the notifiable diseases list of the World Organization for Animal Health (OIE) due to its health impact on domestic ruminants. A total of 27 BTV serotypes have been described and additional serotypes have recently been identified. Since the 2000s, the distribution of BTV has changed in Europe and in the Mediterranean Basin, with continuous BTV incursions involving various BTV serotypes and strains. These BTV strains, depending on their origin, have emerged and spread through various routes in the Mediterranean Basin and/or in Europe. Consequently, control measures have been put in place in France to eradicate the virus or circumscribe its spread. These measures mainly consist of assessing virus movements and the vaccination of domestic ruminants. Many vaccination campaigns were first carried out in Europe using attenuated vaccines and, in a second period, using exclusively inactivated vaccines. This review focuses on the history of the various BTV strain incursions in France since the 2000s, describing strain characteristics, their origins, and the different routes of spread in Europe and/or in the Mediterranean Basin. The control measures implemented to address this disease are also discussed. Finally, we explain the circumstances leading to the change in the BTV status of France from BTV-free in 2000 to an enzootic status since 2018.

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Jack Pilgrim ◽  
Stefanos Siozios ◽  
Matthew Baylis ◽  
Gert Venter ◽  
Claire Garros ◽  
...  

Abstract Background Culicoides imicola (Diptera: Ceratopogonidae) is an important Afrotropical and Palearctic vector of disease, transmitting viruses of animal health and economic significance including African horse sickness and bluetongue viruses. Maternally inherited symbiotic bacteria (endosymbionts) of arthropods can alter the frequency of COI (cytochrome c oxidase subunit I) mitochondrial haplotypes (mitotypes) in a population, masking the true patterns of host movement and gene flow. Thus, this study aimed to assess the mtDNA structure of C. imicola in relation to infection with Candidatus Cardinum hertigii (Bacteroides), a common endosymbiont of Culicoides spp. Methods Using haplotype network analysis, COI Sanger sequences from Cardinium-infected and -uninfected C. imicola individuals were first compared in a population from South Africa. The network was then extended to include mitotypes from a geographic range where Cardinium infection has previously been investigated. Results The mitotype network of the South African population demonstrated the presence of two broad mitotype groups. All Cardinium-infected specimens fell into one group (Fisher’s exact test, P = 0.00071) demonstrating a linkage disequilibrium between endosymbiont and mitochondria. Furthermore, by extending this haplotype network to include other C. imicola populations from the Mediterranean basin, we revealed mitotype variation between the Eastern and Western Mediterranean basins (EMB and WMB) mirrored Cardinium-infection heterogeneity. Conclusions These observations suggest that the linkage disequilibrium of Cardinium and mitochondria reflects endosymbiont gene flow within the Mediterranean basin but may not assist in elucidating host gene flow. Subsequently, we urge caution on the single usage of the COI marker to determine population structure and movement in C. imicola and instead suggest the complementary utilisation of additional molecular markers.


Water ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1437 ◽  
Author(s):  
Martín Hermoso ◽  
María García-Ruiz ◽  
Francisco Osorio

Pollution induced by surface runoff in urban areas constitutes a significant problem. The adoption of control measures aimed at improving the quality of recipient water bodies is a fundamental issue in the management of Mediterranean Basin sewer systems. Previous research in Mediterranean areas using small virtual basins has shown that rainfall regimes have a limited impact on the pollutant load and discharge flowing into a receiving body. The aim of our research was to identify a sizing methodology for stormwater tanks located in the Mediterranean Basin. To achieve this, a numerical model of a sewer system, located in the Southern Iberian Peninsula, was developed. Different patterns related to peak periods of rainfall were considered. Furthermore, efficiency indices were used to evaluate and compare the effects of having a stormwater tank in the system. In our study (which considered a real area), significantly varied values were obtained for the pollution load removal rate (η) and the receiver overflow rate (θ). We nevertheless observed that, in our catchment, at a specific volume of V = 60 m3/ha, η and θ reached constant values without experiencing any significant improvement (η = 0.673 and θ = 0.133). Based on our model, this volume was proposed for the stormwater tank. The ATV (German Association for Water Pollution Control) A 128 standard was applied in order to validate the results, and the specific volume obtained (V = 60 m3/ha) matched with the one proposed. Thus, our proposed methodology is simple and different, and it is very easy to apply by obtaining the values of the efficiency indices η and θ through the development of a Storm Water Management Model (SWMM).


2020 ◽  
Author(s):  
Jack Pilgrim ◽  
Stefanos Siozios ◽  
Matthew Baylis ◽  
Gert Venter ◽  
Claire Garros ◽  
...  

Abstract Background: Culicoides imicola (Diptera: Ceratopogonidae) is an important Afrotropical and Palearctic vector of disease, transmitting viruses of animal health and economic significance. The apparent incursions of C. imicola into mainland Europe via wind-movement events has made it important to trace this species to better predict new areas of arbovirus outbreaks. A widely used method for tracking dispersal patterns of C. imicola employs a phylogeographic approach anchored on the mtDNA marker COI (cytochrome c oxidase subunit I). However, a problem with this approach is that maternally-inherited symbiotic bacteria can alter the frequency of COI mitochondrial haplotypes (mitotypes), masking the true patterns of movement and gene flow.Methods: In this study, the mtDNA structure of C. imicola in relation to Cardinium infection status was investigated through haplotype network analysis. COI Sanger sequences from infected and uninfected individuals were first compared, before extending the haplotype network to include mitotypes from a geographic range where Cardinium infection has previously been investigated.Results: The mitotype network of a South African population, containing both Cardinium-infected and uninfected individuals, demonstrated the presence of two broad mitotype groups. All Cardinium-infected specimens fell into one group (Fisher’s exact test, P<0.001) demonstrating a linkage disequilibrium between symbiont and mitochondria. Furthermore, by extending this haplotype network to include other C. imicola populations from the Mediterranean basin, we revealed mitotype variation between the Eastern and Western Mediterranean basins (EMB and WMB) mirrored Cardinium-infection heterogeneity. Conclusions: These observations suggest that the linkage disequilibrium of Cardinium and mitochondria reflects symbiont gene flow within the Mediterranean basin but may not assist in elucidating host gene flow. Subsequently, we urge caution on the single usage of the COI marker to determine population structure and movement in C. imicola, and instead suggest the complementary utilisation of additional molecular markers.


Author(s):  
Joshua M. White

This book offers a comprehensive examination of the shape and impact of piracy in the eastern half of the Mediterranean and the Ottoman Empire’s administrative, legal, and diplomatic response. In the late sixteenth and seventeenth centuries, piracy had a tremendous effect on the formation of international law, the conduct of diplomacy, the articulation of Ottoman imperial and Islamic law, and their application in Ottoman courts. Piracy and Law draws on research in archives and libraries in Istanbul, Venice, Crete, London, and Paris to bring the Ottoman state and Ottoman victims into the story for the first time. It explains why piracy exploded after the 1570s and why the Ottoman state was largely unable to marshal an effective military solution even as it responded dynamically in the spheres of law and diplomacy. By focusing on the Ottoman victims, jurists, and officials who had to contend most with the consequences of piracy, Piracy and Law reveals a broader range of piratical practitioners than the Muslim and Catholic corsairs who have typically been the focus of study and considers their consequences for the Ottoman state and those who traveled through Ottoman waters. This book argues that what made the eastern half of the Mediterranean basin the Ottoman Mediterranean, more than sovereignty or naval supremacy—which was ephemeral—was that it was a legal space. The challenge of piracy helped to define its contours.


Author(s):  
Matthew D. C. Larsen

The concept of textual unfinishedness played a role in a wide variety of cultures and contexts across the Mediterranean basin in antiquity and late antiquity. Chapter 2 documents examples of Greek, Roman, and Jewish writers reflecting explicitly in their own words about unfinished texts. Many writers claimed to have written unfinished texts on purpose for specific cultural reasons, while others claimed to have written texts that slipped out of their hands somehow with their permission.


Author(s):  
Madadh Richey

The alphabet employed by the Phoenicians was the inheritor of a long tradition of alphabetic writing and was itself adapted for use throughout the Mediterranean basin by numerous populations speaking many languages. The present contribution traces the origins of the alphabet in Sinai and the Levant before discussing different alphabetic standardizations in Ugarit and Phoenician Tyre. The complex adaptation of the latter for representation of the Greek language is described in detail, then some brief attention is given to likely—Etruscan and other Italic alphabets—and possible (Iberian and Berber) descendants of the Phoenician alphabet. Finally, it is stressed that current research does not view the Phoenician and other alphabets as inherently simpler, more easily learned, or more democratic than other writing systems. The Phoenician alphabet remains, nevertheless, an impressive technological development worthy, especially by virtue of its generative power, of detailed study ranging from paleographic and orthographic specifications to social and political contextualization.


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