Statistical analysis of predictors of the effectiveness of complex therapy in patients with skin scarring

2021 ◽  
pp. 7-12
Author(s):  
K. V. Kazantseva. ◽  
V. K. Frolkov ◽  
S. N. Nagornev ◽  
E. V. Gusakova ◽  
M. S. Nagorneva

The variation of indicators that characterize skin scarring increases in patients with metabolic syndrome, which may affect the effectiveness of therapeutic measures. It has been found that pathological processes in the skin scar in the initial state correlate to the greatest extent with the index of insulin resistance, the atherogenic coefficient and the coefficient of antioxidant protection. It is proved that the effectiveness of complex physiotherapy with the addition of the internal intake of medium-mineralized water «Essentuki №17» directly correlates with an increase in tissue sensitivity to insulin and the activation of antioxidant enzymes, as well as with a decrease in dyslipidemia. Linear regression equations are presented to determine significant predictors of treatment effectiveness, which can lead to the creation of individualized therapeutic programs using preformed and natural physical factors.

1985 ◽  
Vol 66 (4) ◽  
pp. 318-318
Author(s):  
L. V. Chernetsova ◽  
A. G. Ibragimova

The comparative analysis of treatment of 76 patients with rheumatoid arthritis using electromagnetic waves of the decimeter range and lithium electrophoresis, depending on the activity of the process and the type of drug therapy.


10.12737/6037 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-7
Author(s):  
Купеев ◽  
R. Kupeev

The article describes the history, effects and application areas of combined laseropforesis and elec-tromyostimulation methods. The inclusion of physical factors into complex therapeutic measures is quite important in a view of complications of isolated drug therapy. Laseropforesis and electromyostimulation are used in treatment of many pathologies in different areas of medicine. Therapeutic effect is realized by the injected drugs and by laser radiation itself. Application of methods does not only eliminate the major symptoms, but also improves microcirculation in the affected area, and throughout the body. This leads to general improvement of the functional systems of the body and contributes to the formation of different adaptation mechanisms.


2021 ◽  
Vol 74 (9) ◽  
pp. 2087-2093
Author(s):  
Igor P. Vakaliuk ◽  
Nataliia V. Savchuk ◽  
Roksolana V. Nesterak ◽  
Haliia B. Kulynych ◽  
Ruslana S. Hryhoryshyn

The aim: To increase the treatment effectiveness of CHF patients after MI with stenting by using magnesium and potassium salts of gluconic acid, eplerenone, and rivaroxaban in complex therapy. Materials and methods: The research was performed at the premises of Ivano-Frankivsk Regional Clinical Cardiology Centre, Ukraine. 84 patients with CHF after past MI were examined. Results and conclusions: A more pronounced anti-ischemic effect has been linked to the use of combination therapy with rivaroxaban on the background of basic therapy (BT) in patients with CHF after MI, compared with the use of magnesium and potassium salts of gluconic acid or eplerenone. The use of eplerenone in the complex treatment of these patients on the background of BT has been proven to provide a pronounced reverse remodeling of the left myocardium in the postinfarction period.


2018 ◽  
Vol 18 (3) ◽  
pp. 23-31
Author(s):  
I A Veres

This study aimed to investigate the effectiveness of the complex therapy of postpartum endometritis (PE) using percutaneous electrophoresis of metronidazole in the main group of puerperas (n = 43, mean age 27.6 ± 5.2 years). Patients from the comparison group (n = 42, mean age 26.3 ± 4.1 years) received only basic treatment according to the protocol. This study determined the severity of the main symptoms of PE in puerperas before and after the treatment using the clinical scale. The effectiveness of the treatment was evaluated quantitatively. Electrophoretic percutaneous administration of metronidazole combined with basic drug therapy exerted a pronounced anti-inflammatory effect at the local and systemic levels and reduced the risk of infection in endometritis. Compared with the basic therapy of PE, the high therapeutic effectiveness of electrophoresis with metronidazole was established.


1985 ◽  
Vol 66 (4) ◽  
pp. 266-269
Author(s):  
L. V. Chernetsova ◽  
A. G. Ibragimova

Despite some success achieved in the treatment of rheumatoid arthritis (RA), the search for more effective methods of therapy for this disease continues to be relevant.


2017 ◽  
pp. 37-40
Author(s):  
S.A. Levenets ◽  
◽  
T.A. Nachotova ◽  
O.H. Verkhoshanova ◽  
N.A. Udovikova ◽  
...  

The objective: to determine near and distant effectiveness of the non-hormonal conventional stimulation therapy in girls with oligomenorrhea and secondary amenorrhea (hypomenstrual syndrome-HMS). Patients and methods. 86 girls aged 13-18 years with HMS were examined in our study. The study involved immunoenzymatic (LH, FSH, PRL, E2, testosterone-T, and insulin-In) and photometric methods (blood serum vitamin E) and pelvic ultrasonography. Therapeutic measures included biostimulants, adaptogens, vitamin and mineral complexes, as well as biguanides and cyproheptadine according to the treatment indications. Results. The immediate treatment efficiency deteriorates significantly in the presence of uterus hypoplasia (36.7% vs. 60.8% without hypoplasia), in cases with blood FSH and LH increase, hypoestrogenemia and in girls with uterine hypoplasia together with a rise in the testosterone level. The remote efficiency of the treatment (1-3 years after the beginning) depends on the duration of the disease (HMS), deteriorating during its existence without treatment for 2 years or more (43.3% vs. 55.9% when duration of the disease is shorter). Hormonal findings demonstrate a negative effect of the initial hypoestrogenemia on the treatment remote efficiency, which has been recorded in 80% of girls with uterine hypoplasia and two times less frequent in cases with good results. Initial hypoestrogenemia has been observed in 11.1% of patients with positive effect and uterine volume appropriate to the age. Three times more frequent this disorder has been recorded in patients with negative results. Conclusion. Further improvement of non-hormonal methods with extensive involvement of non-medicamentous means and verification of the indications for the hormonal drugs prescription is essential to improve the treatment effectiveness of adolescent girls with HMS. Key words: аdolescent girls, oligomenorrhea, secondary amenorrhea, the effectiveness of non-hormonal treatment.


Author(s):  
Malkan Abdrashitova Amhadova ◽  
S. N Garazha ◽  
Z. S.-S Hubaev ◽  
E. N Grishilova ◽  
S. S Hachaturov ◽  
...  

Treatment of inflammatory periodontal diseases occupies one of the leading places at the present stage of development of dentistry. Analysis of clinical, functional and radiographic results of examination of patients with chronic generalized periodontitis of moderate extent before and after treatment showed that the inclusion in the complex of therapeutic measures as local antimicrobial therapy immobilized on polysorb of Doritricin for a short time gives a pronounced therapeutic effect.


2020 ◽  
pp. 22-29
Author(s):  
Z. V. Edilbiev ◽  
A. A. Fedorov

The purpose of the study is to optimize restorative treatment of elderly and senile patients with chronic generalized periodontitis (CGP) by inclusion in the treatment complex of therapeutic physical factors (TPF) and rational pharmacotherapy. Material and methods. The study included 120 elderly and senile patients (at the age from 60 to 75 years old) with CGP. There have been formed 3 groups by simple randomization. In the main group (MG) there were — 4 3patients тhey received standard treatment for CGP and additionally: antihypoxant Hypoxen, vitamin-mineral complex Alphabet50+, mud treatment (ultraphonophoresis of peloid oil solution in the area of upper and lower jaws and mud applications according to the segmentary-reflex method on the projection of cervical-collar zone). In the group of comparison (GC) there were 41 patients they received Hypoxen and Alphabet50+. Against the background of standard therapy — 36 patients of the control group (CG) had only standard therapy for CGP. Dental indices, laser Doppler flowmetry (LDF), and geriarthric index were used to control treatment effectiveness. Results. A comparative analysis of the effectiveness of therapeutic measures showed that, in the MG, on average, the level of periodontal indices immediately decreased by 1,92 (p<0,01) times after the treatment, the level of transcapillary blood flow improved by 1,58 (p<0,01) times. Maintaining the achieved positive results in 6 and 12 months was most noted with the patients of the MG: after 6 months, on average, the level of periodontal indices remained below the initial values — by 1,47 (p<0,01), after 12 months — by 1,20 (p<0,05), the level of transcapillary blood flow, respectively, by 1,44 (p<0,01) and 1,30 (p<0,01) times. Confirmation of correctness of the chosen therapeutic tactics was a significant improvement of mouth cavity — the level of the geriatric index increased by 1,48 (р<0,05) times, remaining statistically above reference values in 6 and 12months — respectively by 1,36 (р<0,01) and 1,27 (р<0,05) times. In the GC the dynamics of these indicators was 10–12% lower, in the CG — statistically lower. Conclusion. The inclusion of TPF and rational pharmacotherapy in the complex of restorative treatment of elderly and senile patients provides a significant increase in the effectiveness of therapeutic measures.


2019 ◽  
Vol 5 (5) ◽  
pp. 96-104
Author(s):  
E. Suerkulov ◽  
I. Yuldashev ◽  
A. Mamyraliev ◽  
N. Zhumashova ◽  
G. Yuldasheva

The article presents the results of the parameters of the lipid peroxidation system and antioxidant protection against the background of complex therapy in children with oral mucosa inflammatory diseases using Laser irradiation of blood and Lizak. Studies have shown that the treatment leads to a decrease in the toxic action of peroxide radicals.


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