RATIO OF TOTAL SLOW AND SUPER SLOW CEREBRAL BIOELECTRICAL ACTIVITY IN CHILDREN WITH HYPOXIA

Author(s):  
A.B. Ivanov ◽  
I.Kh. Borukaeva ◽  
A.A. Molov ◽  
Z.Kh. Abazova ◽  
K.Yu. Shkhagumov

The aim of the study is to identify changes in the total slow and super slow bioelectric activity of the cerebral hemispheres in 8–11-year-old children under reduced oxygen partial pressure in the inhaled air and in norm. Materials and Methods. The authors examined 82 8–11-year-old children. EEG registration was carried out on a complex Russian device "Telepat-103" with computer processing of the results. Slow potentials were recorded using a special computer complex for studying constant potential level (CPL) and cerebral energy consumption "Neuroenergon". Hypoxia was created by a special medical device "Hypoxicator" (Trade Medical). The choice of the oxygen content in the test hypoxic mixture (14 % O2) was based on the results of a three-stage hypoxic test carried out before the complex examination. Results. Hypoxia increases the index and amplitude of delta oscillations and decreases the number of alpha waves in 8–11-year-old children. The results obtained indicate that it is more important to provide the brain with a sufficient amount of oxygen corresponding to its needs than simply to increase the brain blood supply during hypoxia. The study also indicates the contribution of the body's sensitivity to hypoxic response. Under hypoxia, an increase in the constant potential level in the studied brain areas is observed in 8–11-year-old children. An increase in electrical activity during normobaric hypoxia is noted at low baseline values of constant potential level. An increase in the slow electrical brain activity occurs due to the change of brain energy supply according to the biochemical indicators of energy metabolism. Short-term hypoxia is accompanied by a simultaneous increase in slow-wave activity due to delta activity and CPL in 8–11-year-old children. Conclusion. Thus, we can say that a picture of functional brain activity with simultaneous inhibitory phenomena in the cortex is formed. It may reflect the development of a special state of the central nervous system. Key words: constant potential level, electroencephalography, hypoxia, adaptation to hypoxia. Цель работы – выявление изменений суммарной медленной и сверхмедленной биоэлектрической активности полушарий головного мозга у детей в возрасте от 8 до 11 лет в условиях нормального и сниженного парциального давления кислорода во вдыхаемом воздухе. Материалы и методы. Обследовано 82 ребенка 8–11-летнего возраста. Регистрация ЭЭГ осуществлялась на комплексной отечественной установке «Телепат-103» с компьютерной обработкой результатов. Медленные потенциалы фиксировались с помощью специального компьютерного комплекса для исследования уровня постоянных потенциалов (УПП) и энергозатрат головного мозга «Нейроэнергон». Гипоксические условия создавались аппаратом «Гипоксикатор» фирмы Trade Medical. Выбор содержания кислорода в тестирующей гипоксической смеси (14 % О2) основывался на результатах проведенного до комплексного обследования трехступенчатого гипоксического теста. Результаты. У детей от 8 до 11 лет действие гипоксии на головной мозг приводит к возрастанию индекса и амплитуды дельта-колебаний и убыванию числа альфа-волн. Полученные результаты говорят о том, что большое значение имеет не столько усиление кровоснабжения головного мозга при гипоксии, сколько обеспечение мозга достаточным, соответствующим его потребностям, количеством кислорода, а также о роли чувствительности организма к гипоксии. При воздействии гипоксии у детей этого возраста наблюдается возрастание уровня постоянных потенциалов в исследуемых областях головного мозга. При низких фоновых значениях уровня постоянных потенциалов отмечается возрастание электрической активности при нормобарической гипоксии. Возрастание медленной электрической активности головного мозга происходит из-за того, что изменяется энергообеспечение головного мозга по биохимическим показателям энергетического обмена. Действие кратковременной гипоксии сопровождается одновременным возрастанием медленноволновой активности за счет дельта-активности и УПП у детей от 8 до 11 лет. Выводы. Таким образом, можно говорить о том, что формируется своеобразная картина функциональной активности с одновременными тормозными явлениями в коре, что может являться отражением развития особого состояния центральной нервной системы. Ключевые слова: уровень постоянных потенциалов, электроэнцефалография, гипоксия, адаптация к гипоксии.

Author(s):  
V. A. Maksimenko ◽  
A. A. Harchenko ◽  
A. Lüttjohann

Introduction: Now the great interest in studying the brain activity based on detection of oscillatory patterns on the recorded data of electrical neuronal activity (electroencephalograms) is associated with the possibility of developing brain-computer interfaces. Braincomputer interfaces are based on the real-time detection of characteristic patterns on electroencephalograms and their transformation  into commands for controlling external devices. One of the important areas of the brain-computer interfaces application is the control of the pathological activity of the brain. This is in demand for epilepsy patients, who do not respond to drug treatment.Purpose: A technique for detecting the characteristic patterns of neural activity preceding the occurrence of epileptic seizures.Results:Using multi-channel electroencephalograms, we consider the dynamics of thalamo-cortical brain network, preceded the occurrence of an epileptic seizure. We have developed technique which allows to predict the occurrence of an epileptic seizure. The technique has been implemented in a brain-computer interface, which has been tested in-vivo on the animal model of absence epilepsy.Practical relevance:The results of our study demonstrate the possibility of epileptic seizures prediction based on multichannel electroencephalograms. The obtained results can be used in the development of neurointerfaces for the prediction and prevention of seizures of various types of epilepsy in humans. 


2021 ◽  
Vol 11 (11) ◽  
pp. 249-265
Author(s):  
B. Lobasyuk ◽  
L. Bartsevich ◽  
A. Zamkovaya

Justification. Mental retardation is a persistent decrease in human cognitive activity against the background of organic damage to the central nervous system. Neurophysiological diagnostics, in particular electroencephalography (EEG), most adequately reflects the morpho-functional state of the central nervous system, which is the basis of the mechanisms of mental activity, and the originality of the bioelectrical activity of the brain can be considered as the main indicator that determines a decrease in the level of intellectual development and, thereby, characterizes this state. This provision actualizes the search for highly informative indicators of the originality of the bioelectrical activity of the brain in children with intellectual disabilities. Purspose. With the use of periodometric analysis investigate EEG’s indicators and interhemispheric asymmetry of rhythms amplitudes in MR patients. Materials and methods. The EEG was recorded in a state of calm wakefulness with closed eyes with Neuron-Spectrum-2 electroencephalograph. Differences in indicators were tracked using the calculation of the coefficient of compliance (CC), EEG functional asymmetry coefficients in amplitude were determined, too. Results. It was revealed that in MR patients the amplitudes of the rhythms were greater than in healthy subjects. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. Duration indices in the delta, theta and alpha ranges of the EEG in mental retardation compared with the control group were increased, and the indices of the duration of beta rhythms - decreased. When analyzing FMPA in MR persons it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices. Conclusions 1. With mental retardation, the amplitudes of the rhythms were greater than in healthy people. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. 2. The indices of duration in the delta, theta and alpha ranges of the EEG of MR subjects were increased, and the indices of the duration of beta rhythms – decreased. 3. When analyzing FMPA in MR persons, it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices.


2021 ◽  
pp. 102-106
Author(s):  
Claudia Menzel ◽  
Gyula Kovács ◽  
Gregor U. Hayn-Leichsenring ◽  
Christoph Redies

Most artists who create abstract paintings place the pictorial elements not at random, but arrange them intentionally in a specific artistic composition. This arrangement results in a pattern of image properties that differs from image versions in which the same pictorial elements are randomly shuffled. In the article under discussion, the original abstract paintings of the author’s image set were rated as more ordered and harmonious but less interesting than their shuffled counterparts. The authors tested whether the human brain distinguishes between these original and shuffled images by recording electrical brain activity in a particular paradigm that evokes a so-called visual mismatch negativity. The results revealed that the brain detects the differences between the two types of images fast and automatically. These findings are in line with models that postulate a significant role of early (low-level) perceptual processing of formal image properties in aesthetic evaluations.


1976 ◽  
Vol 4 (4) ◽  
pp. 211-222 ◽  
Author(s):  
U J Jovanović

Changes in the electro-encephalogram, and in the electro-oculogram electromyogram, ECG, blood supply, blood pressure, electrical skin activity and neurological/psychiatric findings, were investigated in 100 patients given single administrations of 200 mg of pentoxifylline (BL 191). It is concluded from the changes in the EEG wave patterns that pentoxifylline produces a beneficial effect on the cerebral processes contributing to bio-electrical brain activity. Pentoxifylline can be classed as a substance with microcirculatory/metabolic effects on the brain, which lead to stimulation of psychomotor behaviour.


1984 ◽  
Vol 110 (1) ◽  
pp. 1-15
Author(s):  
W. J. Davis ◽  
M. P. Kovac ◽  
R. P. Croll ◽  
E. M. Matera

Tonic (d.c.) intracellular depolarization of the previously identified phasic paracerebral feeding command interneurones (PCps) in the brain of the carnivorous gastropod Pleurobranchaea causes oscillatory neural activity in the brain, both before and after transecting the cerebrobuccal connectives. Therefore, cycle-by-cycle ascending input from the buccal ganglion is not essential to cyclic brain activity. Instead the brain contains an independent neural oscillator(s), in addition to the oscillator(s) demonstrated previously in the buccal ganglion (Davis et al. 1973). Transection of the cerebrobuccal connectives immediately reduces the previously demonstrated (Kovac, Davis, Matera & Croll, 1983) long-latency polysynaptic excitation of the PCps by the polysynaptic excitors (PSEs) of the PCps. Therefore polysynaptic excitation of the PCps by the PSEs is mediated by an ascending neurone(s) from the buccal ganglion. The capacity of feeding command interneurones to induce neural oscillation in the isolated brain declines to near zero within 1 h after transection of the cerebrobuccal connectives, suggesting that this capacity is normally maintained by ascending information from the buccal ganglion. The results show that this motor system conforms to a widely applicable general model of the neural control of rhythmic behaviour, by which independent neural oscillators distributed widely in the central nervous system are coupled together to produce coordinated movement.


Author(s):  
Jéssyca de Alcantara Galvão

Neuropsychology is a field of psychology and neurosciences that studies the relationships between the central nervous system, cognitive functioning and behavior. Since the beginning, researchers in the field have sought understanding scans of the anatomy of the brain and its correlation with cognitive abilities. Neuropsychology is constantly advancing and transforming, and thus, the findings of this science offer increasingly theoretical and methodological support for professionals and enable interventions and treatments more appropriate to patients. Despite advances in research on cognitive abilities, there are currently difficulties regarding the recognition of individuals with High Skills/Gifted. In addition, in many times, HS/G is confused with disorders. For this reason, this bibliographic study presents the main contributions of Neuropsychology to the identification and development of people with HS/G, denoting the historical aspects, the main advances and the current scenario. The analysis of the data collected in articles, theses, books, laws and public policies in force showed that there is still no precise classification for the understanding of HS/G. What is currently known is that intelligence is one of the factors for identification, but other skills are also considered as artistic, motivational aspects and leadership skills. There is also the association of the results of psychological tests with neuroimaging tests. In continuity of the investigation, the neuropsychological mechanisms of people identified with HS/G were investigated. The results of the researches examined indicate a relationship between the intellectual quotient and brain activity as well as indicative of differences in the functioning and anatomy of the brain of these people when compared with subjects of average intellectual quotient. The last topic addresses the Brazilian reality of children and adolescents with HS/G from the school perspective, the difficulties regarding the identification process and the adequate care for these individuals.


2020 ◽  
Vol 6 (5) ◽  
pp. 128-136
Author(s):  
A. Matkeeva ◽  
E. Kondratieva

The article studies the mechanisms of various types of formation of somatic diseases that underwent perinatal lesions of the central nervous system. And also, the study included 30 children with attention deficit disorder with hyperreactivity in combination with various somatic diseases aged 6 to 8 years and a control group of 30 children (children’s health). The study concluded that the severity of disorders depends on the level of neuropsychic development. Children showed high morbidity, delayed maturation of bioelectrical activity of the brain, impaired autoregulation of cerebral circulation, tension and overstrain of autonomic regulation, imbalance of the immune system, reflecting immaturity of the central, autonomic nervous, immune system.


2009 ◽  
Vol 21 (10) ◽  
pp. 1869-1881 ◽  
Author(s):  
Aviva I. Goller ◽  
Leun J. Otten ◽  
Jamie Ward

In auditory–visual synesthesia, sounds automatically elicit conscious and reliable visual experiences. It is presently unknown whether this reflects early or late processes in the brain. It is also unknown whether adult audiovisual synesthesia resembles auditory-induced visual illusions that can sometimes occur in the general population or whether it resembles the electrophysiological deflection over occipital sites that has been noted in infancy and has been likened to synesthesia. Electrical brain activity was recorded from adult synesthetes and control participants who were played brief tones and required to monitor for an infrequent auditory target. The synesthetes were instructed to attend either to the auditory or to the visual (i.e., synesthetic) dimension of the tone, whereas the controls attended to the auditory dimension alone. There were clear differences between synesthetes and controls that emerged early (100 msec after tone onset). These differences tended to lie in deflections of the auditory-evoked potential (e.g., the auditory N1, P2, and N2) rather than the presence of an additional posterior deflection. The differences occurred irrespective of what the synesthetes attended to (although attention had a late effect). The results suggest that differences between synesthetes and others occur early in time, and that synesthesia is qualitatively different from similar effects found in infants and certain auditory-induced visual illusions in adults. In addition, we report two novel cases of synesthesia in which colors elicit sounds, and vice versa.


2021 ◽  
Vol 6 (1) ◽  
pp. 94-100
Author(s):  
O. I. Shevchenko ◽  
O. L. Lakhman

The aim of the study was to identify the peculiarities of neuropsychological indices disorders depending on changes in the level of constant potential in patients with occupational diseases as a result of physical factors.Materials and methods. The study involved 60 patients with vibration disease caused by local vibration (group I), 106 patients with vibration disease caused by combined exposure to local and general vibration (group II), 101 civil aviation pilots with an established diagnosis of professional sensorineural hearing loss (group III), and 50 healthy men (group IV, comparison group) who were not exposed to vibration and noise due to the specifics of their professional activities. Methods of neuro-energy mapping and neuropsychological testing were used.Results. In groups I–II, compared with group IV, an increase in local levels of constant potential (DC-potential level) in the central, right temporal, and central frontal parts of the brain (2.3 (6.5–3.8) mV; –0.3 (–2.1–2.1); 2.1 (–3.4–6.8) and –0.3 (–3.1–4.3); –2.24 (–6.4–3.8); 0.9 (–3.1–8.5) mV at p = 0.005, 0.007 and 0.004 respectively). Differences in the values of DC-potential level gradients in individuals of group III when compared with group IV reached the level of significance in the central, temporal, occipital leads relative to the central frontal (–5.0 (–13.1–3.8); –4.1 (–9.4–5.1); –2.1 (–10.9–6.6); –6.3 (–15.3–1.8) and 2.9 (–3.0–10.6); 2.2 (–4.5–13.8); 5.6 (–7.6–14.1); –1.4 (–7.5–3.9) mV at p = 0.008; 0.009; 0.009, and 0.007 respectively). Cognitive disorders in patients of groups I–III when compared with group IV correspond to a mild disorder of dynamic, constructive praxis and expressive speech (1.40 (0–1,6); 1.43 (0–1,7); 1.2 (0–1,5) and 0.3 (0–1); 0.2 (0–1); 0.06 (0–1) points at p = 0.008, 0.008 and 0.009 respectively).Conclusions. A common neurofunctional sign of a mild impairment of the cognitive sphere in occupational diseases caused by physical factors is an increase in direct current potential level in the frontal-central and parieto-occipital regions, predominantly of the left hemisphere of the brain.


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