Faculty Opinions recommendation of Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development.

Author(s):  
Harukazu Nakamura
Neuron ◽  
2003 ◽  
Vol 40 (6) ◽  
pp. 1147-1160 ◽  
Author(s):  
Todd McLaughlin ◽  
Christine L. Torborg ◽  
Marla B. Feller ◽  
Dennis D.M. O'Leary

2006 ◽  
Vol 58 (4) ◽  
pp. 525-529 ◽  
Author(s):  
G. Piccione ◽  
A. Costa ◽  
F. Fazio ◽  
F. Grasso ◽  
G. Caola

The maturation of nitrogen metabolism was studied in six Thoroughbred and six Arabian foals. Rectal temperature, heart and respiratory rates and serum concentration of several hematochemical parameters (total protein, urea, uric acid, creatinine, and albumine) were monitored from birth to 5 months of age. In both breeds, all the parameters except albumine showed significant differences over time (P<0.05). The two breeds did not differ from each other at any time point. Statistically significant decreases in urea and creatinine concentrations were related to the growth needs of foals during this critical period of development.


1972 ◽  
Vol 66 (9) ◽  
pp. 297-302
Author(s):  
John J. Knight

□ In summary: (1) Mannerisms are behaviors that the blind child uses to cope with tensions created by situations of frustration, fear, excitement, stimulation deficit, physical activity deprivation, insecurity, etc. (2) The blind child resorts to mannerisms, which are non-instrumental gross motor behaviors learned during early infancy, when he does not have a set of strong instrumental coping behaviors. (3) The blind child's lack of vision impedes the development of essential instrumental behaviors that are learned during infancy, such as reaching and crawling. (4) The blind infant must be given assistance which will enable him to develop each of his instrumental behaviors more completely, especially during the critical period of development for each behavior.


2013 ◽  
Vol 61 ◽  
pp. 233-239 ◽  
Author(s):  
Eduard Ujhazy ◽  
Michal Dubovicky ◽  
Jana Navarova ◽  
Natalia Sedlackova ◽  
Ludovit Danihel ◽  
...  

2015 ◽  
Vol 75 (6) ◽  
pp. 621-640 ◽  
Author(s):  
Hong-Ping Xu ◽  
Timothy J. Burbridge ◽  
Ming-Gang Chen ◽  
Xinxin Ge ◽  
Yueyi Zhang ◽  
...  

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Juliana M Rosa ◽  
Rémi Bos ◽  
Georgeann S Sack ◽  
Cécile Fortuny ◽  
Amit Agarwal ◽  
...  

Neuron-glia interactions play a critical role in the maturation of neural circuits; however, little is known about the pathways that mediate their communication in the developing CNS. We investigated neuron-glia signaling in the developing retina, where we demonstrate that retinal waves reliably induce calcium transients in Müller glial cells (MCs). During cholinergic waves, MC calcium transients were blocked by muscarinic acetylcholine receptor antagonists, whereas during glutamatergic waves, MC calcium transients were inhibited by ionotropic glutamate receptor antagonists, indicating that the responsiveness of MCs changes to match the neurotransmitter used to support retinal waves. Using an optical glutamate sensor we show that the decline in MC calcium transients is caused by a reduction in the amount of glutamate reaching MCs. Together, these studies indicate that neurons and MCs exhibit correlated activity during a critical period of retinal maturation that is enabled by neurotransmitter spillover from retinal synapses.


2016 ◽  
Author(s):  
John H. Duffus ◽  
Monica Nordberg ◽  
Douglas M. Templeton

2007 ◽  
Vol 10 (3) ◽  
pp. 2156759X0701000
Author(s):  
Christopher A. Sink ◽  
Cher N. Edwards ◽  
Sarah J. Weir

This article documents the challenges that young children face as they move from kindergarten to first grade and the important role that elementary school counselors can play in working with students, parents/caregivers, and teachers during this critical period of development. Research- and practitioner-based recommendations for effective interventions are discussed.


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