Faculty Opinions recommendation of TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo.

Author(s):  
David Serreze
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Vol 179 (1) ◽  
pp. 211-220 ◽  
Author(s):  
Marsha S. Russell ◽  
Monica Iskandar ◽  
Oksana L. Mykytczuk ◽  
John H. E. Nash ◽  
Lakshmi Krishnan ◽  
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Key PointsCLEC-1 is restricted to CD16− myeloid DCs in human blood and acts as an inhibitory receptor to restrain downstream Th17 activation. CLEC-1–deficient rats highlight an in vivo function for CLEC-1 in preventing excessive T-cell priming and effector Th responses.


Cell Reports ◽  
2015 ◽  
Vol 13 (2) ◽  
pp. 399-411 ◽  
Author(s):  
Jan Dudeck ◽  
Shanawaz Mohammed Ghouse ◽  
Christian H.K. Lehmann ◽  
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...  

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