Faculty Opinions recommendation of Comparison of the clinical outcome of different beta-blockers in heart failure patients: a retrospective nationwide cohort study.

2014 ◽  
Author(s):  
Marrick Kukin ◽  
Saurav Chatterjee ◽  
Manpreet Singh Sabharwal
Keyword(s):  
Heart Failure ◽  
Cohort Study ◽  
Clinical Outcome ◽  
Beta Blockers ◽  
Heart Failure Patients

Comparison of the clinical outcome of different beta-blockers in heart failure patients: a retrospective nationwide cohort study

2014 ◽  
Vol 16 (6) ◽  
pp. 678-684 ◽  
Author(s):  
Rasmus Bølling ◽  
Nikolai Madrid Scheller ◽  
Lars Køber ◽  
Henrik Enghusen Poulsen ◽  
Gunnar H. Gislason ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cohort Study ◽  
Clinical Outcome ◽  
Beta Blockers ◽  
Heart Failure Patients

Differences in clinical outcome of first time admitted heart failure patients compared to patients treated in a specialised heart failure unit

2008 ◽  
Vol 7 ◽  
pp. 7-7
Author(s):  
M ELHENICKY ◽  
M RESL ◽  
D STELZENEDER ◽  
A HAMMER ◽  
G GOUYA ◽  
...  
Keyword(s):  
Heart Failure ◽  
Clinical Outcome ◽  
Heart Failure Patients ◽  
Heart Failure Unit ◽  
First Time

scholarly journals Relationship of anemia and clinical outcome in heart failure patients with preserved versus reduced ejection fraction in a rural area of Thailand

2020 ◽  
Vol 30 ◽  
pp. 100597
Author(s):  
Kittayaporn Chairat ◽  
Wipharak Rattanavipanon ◽  
Krittika Tanyasaensook ◽  
Busba Chindavijak ◽  
Suvatna Chulavatnatol ◽  
...  
Keyword(s):  
Heart Failure ◽  
Clinical Outcome ◽  
Ejection Fraction ◽  
Rural Area ◽  
Reduced Ejection Fraction ◽  
Heart Failure Patients ◽  
Relationship Of

Discharge heart rate and clinical outcomes in hospitalized heart failure patients with coexisted atrial fibrillation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
F Xing ◽  
X Bai ◽  
J Li
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Heart Rate ◽  
Clinical Outcome ◽  
Confidence Interval ◽  
Clinical Outcomes ◽  
Beta Blockers ◽  
Funding Source ◽  
Proportional Hazard ◽  
Cox Proportional Hazard

Abstract Background Whether discharge heart rate for hospitalized heart failure (HF) patients with coexisted atrial fibrillation (AF) is associated with long-term clinical outcomes and whether this association differs between patients with and without beta-blockers have not been well studied. Purpose We investigated the associations between discharge heart rate and clinical outcomes in hospitalized HF patients with coexisted AF, while stratified to beta-blockers at discharge. Methods The study cohort included 1631 HF patients hospitalized primarily with AF, which was from the China PEACE Prospective Heart Failure Study. Clinical outcome was 1-year combined all-cause mortality and HF hospitalization after discharge. We analyzed association between outcome and heart rate at discharge with restricted cubic spline and Cox proportional hazard ratios (HR). Results The median age was 68 (IQR: 60- 77) years, 41.9% were women, discharge heart rate was (median (IQR)) 75 (69- 84) beats per minute (bpm), and 60.2% received beta-blockers at discharge. According to the result of restricted cubic spline plot, the relationship between discharge heart rate and clinical outcome may be nonlinear (P<0.01). Based on above result, these patients were divided into 3 groups: lowest <65 bpm, middle 65–86 bpm and highest ≥87 bpm, clinical outcomes occurred in 128 (64.32%), 624 (53.42%) and 156 (59.32%) patients in the lowest, middle, and highest groups respectively. In the Cox proportional hazard analysis, the lowest and highest groups were associated with increased risks of clinical outcome compared with the middle group (HR: 1.289, 95% confidence interval (CI): 1.056 - 1.573, p=0.013; HR: 1.276, 95% CI: 1.06 - 1.537, p=0.01, respectively). And a significant interaction between discharge heart rate and beta-blocker use was observed (P<0.001 for interaction). Stratified analysis showed the lowest group was associated with increased risks of clinical outcomes in patients with beta-blockers (HR: 1.584, 95% confidence interval (CI): 1.215–2.066, p=0.001). Conclusion There may be a U-curve relationship between discharge heart rate and clinical outcomes in hospitalized HF patients with coexisted AF. They may have the best clinical outcomes with heart rates of 65 - 86 bpm. And strict heart rate control (<65 bpm) may be avoided for patients who discharge with beta-blockers. Figure 1 Funding Acknowledgement Type of funding source: Other. Main funding source(s): This work was supported by the National Key Research and Development Program (2017YFC1310803) from the Ministry of Science and Technology of China; the CAMS Innovation Fund for Medical Science (2017-I2M-B&R-02); the 111 Project from the Ministry of Education of China (B16005).

Improvement in Exercise Capacity by Exercise Training is associated with Favorable Clinical Outcome in Advanced Chronic Heart Failure Patients

2014 ◽  
Vol 20 (10) ◽  
pp. S184
Author(s):  
Michio Nakanishi ◽  
Reon Kumasaka ◽  
Tetsuo Arakawa ◽  
Teruo Noguchi ◽  
Takahiro Ohara ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Exercise Training ◽  
Clinical Outcome ◽  
Exercise Capacity ◽  
Heart Failure Patients ◽  
Favorable Clinical Outcome

scholarly journals The Impact of Treatment with Beta-Blockers upon Mortality in Chronic Heart Failure Patients

2016 ◽  
Vol 4 (1) ◽  
pp. 94-97 ◽  
Author(s):  
Borjanka Taneva ◽  
Daniela Caparoska
Keyword(s):  
Heart Failure ◽  
Relative Risk ◽  
Chronic Heart Failure ◽  
Beta Blocker ◽  
Cardiovascular Mortality ◽  
Conventional Therapy ◽  
Therapy Group ◽  
Beta Blockers ◽  
Control Group ◽  
Heart Failure Patients

BACKGROUND: Besides the conventional therapy for heart failure, the diuretics, cardiac glycosides and ACE-inhibitors, current pharmacotherapy includes beta-blockers, mainly because of their pathophysiological mechanisms upon heart remodeling.AIM: The study objective was to assess the cardiovascular mortality in the beta-blocker therapy group and to correlate it with the mortality in the control group as well as to correlate the combined outcome of death and/or hospitalization for cardiovascular reason between the two groups.               MATERIALS AND METHODS: The study included 113 chronic heart failure patients followed up for a period of 18 months. The therapy group received conventional therapy plus the target dose of beta blockers, and the control group received the conventional therapy only. The therapy group was divided in three separate subgroups in terms of the type of beta-blocker (Metoprolol subgroup, Bisoprolol and Carvedilol subgroup). To compare the mortality and the combined outcome, the RRR (relative risk reduction) and NNT (number needed to treat) were used, as well as the survival analysis by Kaplan-Meier.RESULTS: The results showed the following: in regards of the cardiovascular mortality, the relative risk for death in the therapy group was 34%, which, though statistically not significant, is of great clinical significance. In regards of the combined outcome (death and/or number of hospitalizations) the results showed a RRR of 40% in the therapy group compared to the control group, which is statistically highly significant.CONCLUSION: The study confirmed that patients with stable chronic heart failure, treated with optimal doses of beta-blockers, show a significant reduction of the risk from death as well as combined outcome (death and/or number of hospitalizations).

Clinical Outcome and Quality of Life with an Ambulatory Counterpulsation Pump (iVAS) in Advanced Heart Failure Patients

2018 ◽  
Vol 24 (11) ◽  
pp. 810
Author(s):  
V. JEEVANANDAM ◽  
D. ONSAGER ◽  
T. SONG ◽  
T. OTA ◽  
C. JURICEK ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Clinical Outcome ◽  
Advanced Heart Failure ◽  
Heart Failure Patients
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