Faculty Opinions recommendation of One-year mortality outcomes and hospital readmissions of patients admitted with acute heart failure: Data from the Trivandrum Heart Failure Registry in Kerala, India.

AbstractFrailty is a common comorbidity associated with adverse events in patients with heart failure, and early recognition is key to improving its management. We hypothesized that the AST to ALT ratio (AAR) could be a marker of frailty in patients with heart failure. Data from the FRAGILE-HF study were analyzed. A total of 1327 patients aged ≥ 65 years hospitalized with heart failure were categorized into three groups based on their AAR at discharge: low AAR (AAR < 1.16, n = 434); middle AAR (1.16 ≤ AAR < 1.70, n = 487); high AAR (AAR ≥ 1.70, n = 406). The primary endpoint was one-year mortality. The association between AAR and physical function was also assessed. High AAR was associated with lower short physical performance battery and shorter 6-min walk distance, and these associations were independent of age and sex. Logistic regression analysis revealed that high AAR was an independent marker of physical frailty after adjustment for age, sex and body mass index. During follow-up, all-cause death occurred in 161 patients. After adjusting for confounding factors, high AAR was associated with all-cause death (low AAR vs. high AAR, hazard ratio: 1.57, 95% confidence interval, 1.02–2.42; P = 0.040). In conclusion, AAR is a marker of frailty and prognostic for all-cause mortality in older patients with heart failure.

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Vulnerable Phase of Acute Heart Failure and its Association with Hospital Readmissions Reduction Program

Current Problems in Cardiology ◽

10.1016/j.cpcardiol.2021.100904 ◽

2021 ◽

pp. 100904

Author(s):

Azka Latif ◽

Noman Lateef ◽

Scott Lundgren ◽

Vikas Kapoor ◽

Muhammad Junaid Ahsan ◽

...

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

Hospital Readmissions ◽

Reduction Program

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Prognostic value of biomarkers and co-morbidities in patients with acute heart failure: One-year follow-up study

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh160225030p ◽

2017 ◽

Vol 145 (3-4) ◽

pp. 118-123

Author(s):

Dejan Petrovic ◽

Marina Deljanin-Ilic ◽

Sanja Stojanovic

Keyword(s):

Heart Failure ◽

Renal Failure ◽

Chronic Renal Failure ◽

Acute Heart Failure ◽

Troponin I ◽

Prognostic Significance ◽

Systolic Pressure ◽

High Sensitivity ◽

Clinical Group ◽

One Year

Introduction/Objective. Clinical risk stratification of patients hospitalized due to acute heart failure (AHF) applying B-type natriuretic peptide (BNP), troponin I (TnI), and high-sensitivity C-reactive protein (hsCRP) biochemical markers can contribute to early diagnosis of AHF and lower mortality rates. The aim of this study was to investigate the prognostic significance of biomarkers (BNP, TnI, and hsCRP) and co-morbidities concerning one-year mortality in patients with AHF. Methods. Clinical group comprised 124 consecutive unselected patients, age 60?80 years, treated at the Coronary Care Unit of the Niska Banja Institute, Nis. The patients were monitored for one year after the discharge. During the first 24 hours after admission, BNP, TnI, and hsCRP were measured in fasting serum. Results. Total one-year mortality was 29.8%. The levels of serum BNP were significantly higher in the group of non-survivors compared to the group of survivors (1353.8 ?} 507.8 vs. 718.4 ?} 387.6 pg/mL, p < 0.001). We identified several clinical and biochemical prognostic risk factors by univariate and multivariate analysis. Independent predictors of one-year mortality were the following: BNP, TnI, depression, hypotension, chronic renal failure, ejection fraction, and right-ventricle systolic pressure. Conclusion. The presence of BNP and TnI biomarkers and several co-morbidities such as depression or chronic renal failure have significant influence on one-year mortality in patients with AHF.

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Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials)

The American Journal of Cardiology ◽

10.1016/j.amjcard.2016.09.038 ◽

2017 ◽

Vol 119 (2) ◽

pp. 290-296 ◽

Cited By ~ 26

Author(s):

Jasper Tromp ◽

Jozine M. ter Maaten ◽

Kevin Damman ◽

Christopher M. O'Connor ◽

Marco Metra ◽

...

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

Serum Potassium ◽

Failure Data

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Abstract 17352: Differences in Clinical Characteristics, Risk Factors, Rate of Recurrence and 1-year Outcome Between Acute Heart Failure Patients With Stroke or TIA and Those Without This Co-morbidity. Results From the Gulf aCute heArt failuRe rEgistry (gulf Care)

Circulation ◽

10.1161/circ.130.suppl_2.17352 ◽

2014 ◽

Vol 130 (suppl_2) ◽

Author(s):

Mohammed A Al Hashemi ◽

Kadhim Sulaiman ◽

Jassim Al-Suwaidi ◽

Khalid F AlHabib ◽

Husam AlFaleh ◽

...

Keyword(s):

Heart Failure ◽

Acute Heart Failure ◽

Clinical Characteristics ◽

De Novo ◽

Stroke Patients ◽

Lv Dysfunction ◽

Co Morbidity ◽

History Of ◽

One Year ◽

Ischemic Attack

Background: Chronic heart failure (CHF) is a known risk for stroke and morbidities and mortalities are known to be higher in CHF patients compared to stroke patients without CHF we here study the prevalence and the clinical significance in a group of patient with stroke or transient ischemic attack (TIA) who were admitted to hospital with acute heart failure (AHF) compared to those without stroke and are admitted with acute heart failure Methods: Data were derived from a prospective, multicenter, multinational study of 5005 patients hospitalized with AHF from February 2013 to November 2012. Data were analyzed according to the presence or absence of Stroke or bronchial TIA. Demographic, management, in-hospital and 1-year outcomes were compared Results: Stroke patients were likely to have a decompensation of chronic failure rather than De-Novo AHF when compared to those without Stroke/TIA (see table). Stroke patients were older; more likely to be female, have history of DM, HTN, dyslipidemia and CKD. Stroke patients were likely to have Atrial fibrillation, PVD, systolic LV dysfunction as well as CAD when compared to those without Stroke, they were also more likely receive NIV, IV inotropes and likely to have had cardiac PCI prior to this admission with AHF. Stroke patients had higher recurrence of stroke and one-year mortality rates. Conclusion: Patients who presented with AHF and history of stroke/TIA were having different clinical characteristics as well as comorbidities as compared to those without Stroke, with worse in-hospital and one-year outcome. The current study underlies the need to aggressively manage these high-risk patients.

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SEVERITY OF ACUTE KIDNEY INJURY DURING HOSPITALIZATION AS A PROGNOSTIC FACTOR IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE: DATA FROM THE KOREAN ACUTE HEART FAILURE (KORAHF) REGISTRY

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(16)31406-1 ◽

2016 ◽

Vol 67 (13) ◽

pp. 1405

Author(s):

Sung Woo Cho ◽

Ga Yeon Lee ◽

Eun-Seok Jeon ◽

Minsun Kim ◽

Haseong Chang ◽

...

Keyword(s):

Heart Failure ◽

Acute Kidney Injury ◽

Prognostic Factor ◽

Acute Heart Failure ◽

Acute Decompensated Heart Failure ◽

Kidney Injury ◽

Decompensated Heart Failure ◽

Failure Data

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P6361Prognostic value of discharge heart rate in acute heart failure patients: more relevant in atrial fibrillation?

European Heart Journal ◽

10.1093/eurheartj/ehz746.0957 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

R Vidal-Perez ◽

R Agra-Bermejo ◽

D Pascual-Figal ◽

F Gude Sampedro ◽

C Abou Jokh ◽

...

Keyword(s):

Heart Failure ◽

Atrial Fibrillation ◽

Heart Rate ◽

Sinus Rhythm ◽

Acute Heart Failure ◽

Left Ventricular Ejection ◽

Long Term Outcomes ◽

All Cause Mortality ◽

One Year

Abstract Background The prognostic impact of heart rate (HR) in acute heart failure (AHF) patients is not well known especially in atrial fibrillation (AF) patients. Purpose The aim of the study was to evaluate the impact of admission HR, discharge HR, HR difference (HRD) (admission- discharge) in AHF patients with sinus rhythm (SR) or AF on long- term outcomes. Methods We included 1398 patients consecutively admitted with AHF between October 2013 and December 2014 from a national multicentric, prospective registry. Logistic regression models were used to estimate the association between admission HR, discharge HR and HR difference and one- year all-cause mortality and HF readmission. Results The mean age of the study population was 72±12 years. Of these, 594 (42.4%) were female, 655 (77.8%) were hypertensive and 655 (46.8%) had diabetes. Among all included patients, 745 (53.2%) had sinus rhythm and 653 (46.7%) had atrial fibrillation. Only discharge HR was associated with one-year all-cause mortality (Relative risk (RR)= 1.182, confidence interval (CI) 95% 1.024–1.366, p=0.022) in SR. In AF patients discharge HR was associated with one-year all-cause mortality (RR= 1.276, CI 95% 1.115–1.459, p≤0.001). We did not observe a prognostic effect of admission HR or HRD on long-term outcomes in both groups. This relationship is not dependent on left ventricular ejection fraction (Figure 1) Effect of post-discharge heart rate Conclusions In AHF patients lower discharge HR, neither the admission nor the difference, is associated with better long-term outcomes especially in AF patients Acknowledgement/Funding Heart Failure Program of the Red de Investigaciόn Cardiovascular del Instituto de Salud Carlos III, Madrid, Spain (RD12/0042) and the Fondo Europeo de

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