Faculty Opinions recommendation of Republished: Which antibody and which cancer in which paraneoplastic syndromes?

Author(s):  
John Greenlee ◽  
Melissa Cortez
Medic ro ◽  
2020 ◽  
Vol 2 (134) ◽  
pp. 47
Author(s):  
Dorina Nastasia Petra ◽  
Anca Paula Şulea ◽  
Maria Andrada Jiga ◽  
Robert Adrian Dumbravă ◽  
Dragoş-Gabriel Iancu ◽  
...  

2019 ◽  
Vol 0 (6) ◽  
pp. 44-58
Author(s):  
N. B. Gubergrits ◽  
O. O. Dyadik ◽  
N. V. Bieliaieva ◽  
K. Yu. Lynevska

2021 ◽  
Vol 28 (3) ◽  
pp. 1744-1750
Author(s):  
Laura Burgess ◽  
Marissa Keenan ◽  
Alan Liang Zhou ◽  
Kiefer Lypka ◽  
Delvina Hasimja Saraqini ◽  
...  

Approximately 20% of renal cell carcinoma (RCC) is diagnosed because of paraneoplastic manifestations. RCC has been associated with a large variety of paraneoplastic syndromes (PNS), but it is rarely associated with PNS vasculitis. We present a case of a previously healthy male who presented with systemic vasculitis; bitemporal headaches, diplopia, polyarthritis, palpable purpura, tongue lesion, peri-orbital edema, scleritis, chondritis and constitutional symptoms. He was subsequently found to have oligometastatic RCC. Both his primary lesion and site of oligometastasis were treated with stereotactic radiotherapy (SBRT) and resulted in the resolution of his vasculitis, as well as sustained oncologic response. This is the first case to demonstrate that effective sustained treatment for PNS vasculitis due to oligometastatic RCC is possible with SBRT.


2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110040
Author(s):  
Weimin Tao ◽  
Qin Yan ◽  
Yao Zhou ◽  
Yanli Wang ◽  
Zhiqiang Liu ◽  
...  

Paraneoplastic syndromes are rarely seen in gynecological tumors especially in endometrial cancer. Early identification of paraneoplastic syndromes plays a significant role in the treatment and prognosis of cancer. Here, we reported a rare case with endometrial cancer with a 2.7 cm × 2.2 cm × 3.4 cm lesion in the posterior cervix presenting leukemoid reaction and hypercalcemia as paraneoplastic syndromes simultaneously. During the progress of the endometrial cancer, her leukocyte level rose up to 60.7 × 109/L after anti-infection treatment. Meanwhile, the patient represented a series of severe clinical situation including hypercalcemia, hypokalemia, metabolic alkalosis. and respiratory failure. Finally, the patient died of respiratory circulatory failure 2 weeks later. In addition to symptomatic treatment, possible treatment targeted on the primary tumor as early as possible might help to improve the clinical prognosis.


Blood ◽  
2021 ◽  
Author(s):  
Lakshmi Nayak ◽  
Tracy T Batchelor

Neurologic complications of lymphoid cancer can be challenging to recognize and treat. The nervous system can be affected directly by hematogenous or local spread of lymphoma. Indirect neurologic effects of lymphoma include paraneoplastic syndromes and vascular complications. Lymphoma treatments can also cause neurologic complications. Early identification and treatment are crucial to stabilize or reverse neurologic deficits, prevent further nervous system injury, and to optimize overall oncologic therapy. This article provides an overview of different neurologic complications of lymphoma and its treatments, in addition to presentation of case studies that emphasize commonly encountered clinical scenarios.


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