scholarly journals Intervenção nutricional com ênfase na suplementação de vitamina d, proteína do soro do leite e aminoácidos essenciais na melhora da saúde muscular em idosos sarcopênicos: uma revisão de literatura / Nutritional intervention with emphasis on the supplementation of vitamin d, milk serum protein and essensential amino acids in improving muscular health in sarcopenic elderly people: a literature review

2021 ◽  
Vol 4 (3) ◽  
pp. 11926-11937
Author(s):  
Guilherme Faustino Da Silva ◽  
Laíse Villarim Oliveira ◽  
Ana Clara Pereira Rolim ◽  
Natália Ramos Dos Santos ◽  
Larissa Cordeiro De Araújo ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Philip Newsholme

AbstractVarious nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.


Author(s):  
Philip Newsholme

AbstractVarious nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.


Author(s):  
André Oliveira Ferro ◽  
Mariana Soares de Araújo ◽  
Érika Ruanna Alencar da Silva ◽  
Flávia Thalia Guedes Farias ◽  
Ana Julya César Rodrigues ◽  
...  

Analisar a efetividade da terapia com vitamina D em idosos com depressão, em comparação ao uso de placebos. Revisão sistemática de literatura. Para seu desenvolvimento, efetuou-se pesquisa em bases de dados para a saúde, seguida da aplicação dos critérios de elegibilidade, considerando textos completos em inglês, português e Ensaios Clínicos Randomizados publicados entre 2008-2020. Em sequência, mediante leitura dos títulos e resumos aos pares, seis publicações compuseram a amostragem final. Os achados indicaram, majoritariamente, inexistir diferenças significativas entre os sintomas depressivos em idosos suplementados com a vitamina D em comparação ao uso do placebo. Os achados não mostraram evidências significativas, atestando que a suplementação da vitamina D não refletiu melhores resultados para a depressão em idosos. Contudo, importante mencionar que uma publicação registrou melhorias em pacientes dialíticos com depressão vascular, melhorando o funcionamento cardiovascular desses pacientes após a suplementação.Descritores: Vitamina D, Depressão, Idosos. Effectiveness of vitamin d therapy in elderly people with depressionAbstract: To analyze the effectiveness of vitamin D therapy in elderly people with depression, compared to the use of placebos. Systematic literature review. For the development of the study, a search was performed in the health’s databases, followed by the application of the eligibility criteria, considering the complete texts in English and Portuguese; Randomized Clinical Trials published between the 2008-2020. In sequence, through the reading of the titles and abstracts in pairs, six publications made up the final sample. The selected articles stated that there were no significant differences between depressive symptoms in the elderly related to vitamin D supplementation compared to the use of placebo. The findings showed no significant evidence, attesting that vitamin D supplementation did not reflect better results for depression in the elderly. However, it is important to mention that one publication recorded improvements in dialysis patients with vascular depression, improving the cardiovascular functioning of these patients after supplementation.Descriptors: Vitamin D, Depression, Seniors. Efectividad de la terapia con vitamina d en ancianos con depresiónResumen: Analizar la efectividad de la terapia con vitamina D en ancianos con depresión, en comparación con el uso de placebos. Revisión sistemática de la literatura. Para el desarrollo del estudio se realizó una búsqueda en las bases de datos de salud, seguida de la aplicación de los criterios de elegibilidad, considerando los textos completos en inglés y portugués; ensayos clínicos aleatorizados publicados entre 2008-2020. En secuencia, mediante la lectura de títulos y resúmenes por parejas, seis publicaciones conformaron la muestra final. Los artículos seleccionados indicaron que no hubo diferencias significativas entre los síntomas depresivos en los ancianos relacionados con la suplementación con vitamina D en comparación con el uso de placebo. Los hallazgos no mostraron evidencia significativa, lo que atestigua que la suplementación con vitamina D no reflejaba mejores resultados para la depresión en los ancianos. Sin embargo, es importante mencionar que una publicación registró mejoras en pacientes de diálisis con depresión vascular, mejorando el funcionamiento cardiovascular de estos pacientes después de la suplementación.Descriptores: Vitamina D, Depresión, Mayores.


2020 ◽  
Vol 16 (7) ◽  
pp. 1015-1027
Author(s):  
Mohammad Bagherniya ◽  
Zahra Khorasanchi ◽  
Mina S. Bidokhti ◽  
Gordon A. Ferns ◽  
Mitra Rezaei ◽  
...  

Background: Vitamin D deficiency is a common medical condition worldwide. In Iran, it has been reported that between 30-90% of people have vitamin D deficiency. However, its distribution in different parts of the country and among different age and regional groups is unclear. Therefore, the aim of this study was to review the recent literature on vitamin D deficiency in Iran. Methods: The literature review was performed using Web of Science, PubMed-Medline, Scopus and Scientific Information Database (SID) with a cut-off date of November 2016 to identify articles on vitamin D status in Iran published in the last 10 years. Studies in English and Persian that reported vitamin D levels in male and female subjects of all age groups and in healthy populations were included. Results: From 325 studies that were initially retrieved, 82 articles met the inclusion criteria. A high prevalence of vitamin D deficiency was reported, and in some regions, this was reported as >90% and was found in all age groups and in all regions of Iran. Conclusion: This review highlights the very high prevalence of vitamin D deficiency in Iran. It will be important to recognize the importance of vitamin D deficiency as a major public health problem in Iran.


2000 ◽  
Vol 70 (2) ◽  
pp. 181-195 ◽  
Author(s):  
P.I. Hynd

AbstractThe rôle of various classes of nutrients (energy substrates, vitamins, minerals, amino acids) in the production of wool and hair from follicles, is considered for a variety of animal species. The wool and hair follicle have evolved a number of interesting features of carbohydrate metabolism including glutaminolysis, aerobic glycolysis, significant activity of the pentose phosphate pathway, and storage and mobilisation of glycogen. Presumably the necessity to continue to produce fibre despite fluctuations in the supply of oxygen and nutrients has resulted in some of these unique features, while others reflect the high level of DNA and protein synthesis occurring in the follicle. While it is considered that energy does not normally limit fibre growth, the relative contributions of aerobic and anerobic metabolism will greatly influence the amount of ATP available for follicle activity, such that energy availability may at times alter fibre growth. Alopecia and deficient fibre growth are consistent outcomes of deficiencies of biotin, riboflavin, pyridoxine, folate and pantothenic acid, but the precise rôles of these vitamins in follicle function await elucidation. Folate, in particular appears to play an important rôle in wool production, presumably reflecting its involvement in methionine metabolism. Cholecalciferol (vitamin D) significantly alters fibre growth in cultured follicles; vitamin D receptors are located in the outer root sheath, bulb, and dermal papilla of the follicle; and alopecia occurs in humans with defects in the vitamin D receptor. Retinol (vitamin A), too, appears to influence follicle function by altering keratinocyte proliferation and differentiation, with direct effects on the expression of keratin genes. The receptors for the retinoids are present in the keratogenous zone, the outer root sheath, the bulb, and the sebaceous glands. Vitamin A may also act indirectly on follicle function by influencing the activity of the insulin-like and epidermal growth factors and by altering vitamin D activity. At present there is little evidence implicating alpha-tocopherol (vitamin E) or phytylmenaquinone (vitamin K) in follicular events. Of the minerals, only copper and zinc have been shown to have direct effects on follicle function, independent of effects on food intake. Copper has direct effects on the activity of an unidentified enzyme on oxidation of thiol groups to form disulphide linkages. Wool produced by copper-deficient sheep lacks crimp, is weak and lustrous. Copper is also necessary for the activity of tyrosinase and the tyrosinase-related proteins involved in melanin synthesis. Zinc, like copper, is required for the normal keratinization of fibres but again, the precise rôle has yet to be elucidated. While the importance of amino acid supply for wool growth has long been established, there are still some unaswered questions such as; what are the effects of amino acids on fibre growth in animals other than sheep; what are the characteristics of the amino acid transport genes and proteins operating in the wool and hair follicle; and what are the specific rôles for amino acids in follicle function.


1989 ◽  
Vol 18 (6) ◽  
pp. 392-397 ◽  
Author(s):  
J. M. QUESADA ◽  
I. JANS ◽  
P. BENITO ◽  
J. A. JIMENEZ ◽  
R. BOUILLON

1967 ◽  
Vol 1 (3) ◽  
pp. 219-219
Author(s):  
John Grose ◽  
Charles Scriver ◽  
John Fawcett

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