Ganglion cyst arising from the composite occipito-atlanto-axial joint cavity in a cat

2014 ◽  
Vol 27 (04) ◽  
pp. 319-323
Author(s):  
S. Sadahiro ◽  
M. Nishimura ◽  
Y. Miyazaki ◽  
M. Shibata ◽  
T. Aikawa
Keyword(s):  
Ganglion Cyst ◽  
Clinical Signs ◽  
Cord Compression ◽  
Histological Evaluation ◽  
Dorsal Spinal Cord ◽  
Joint Cavity ◽  
Initial Inability ◽  
History Of ◽  
Atlanto Axial Joint

SummaryA four-year-old, female spayed Domestic Longhaired cat was referred for evaluation with a two month history of initial inability to jump progressing to ambulatory tetraparesis. Magnetic resonance imaging studies demonstrated a cystic lesion arising from the composite occipito-atlanto-axial joint cavity and extending to the region of the occipital bone and the axis. The lesion surrounded the spinal canal, causing moderate dorsal spinal cord compression at the atlanto-occipital joint. A dynamic myelographic study demonstrated attenuation of the dorsal contrast column at the atlanto-occipital joint when the cervical spine was positioned in extension. Partial excision of the cyst capsule by a ventral approach resulted in long-term (64 months) resolution of clinical signs. Histological evaluation was consistent with a ganglion cyst. An intra-spinal ganglion cyst arising from the composite occipito-atlanto-axial joint cavity may be considered as an uncommon differential diagnosis for cats with cervical myelopathy.

scholarly journals Cervical C7 ganglion cyst causing compressive myelopathy: A rare case report

2019 ◽  
Vol 10 ◽  
pp. 61
Author(s):  
Charandeep Singh Gandhoke ◽  
Siu Kei David Mak ◽  
Nishal Kishinchand Primalani ◽  
Eng Tah Goh ◽  
Hwei Yee Lee ◽  
...  
Keyword(s):  
Ganglion Cyst ◽  
Cord Compression ◽  
Sensory Level ◽  
Facet Joints ◽  
Complete Excision ◽  
Lower Extremity Weakness ◽  
Ganglion Cysts ◽  
Rare Case Report ◽  
History Of ◽  
Compressive Myelopathy

Background: Juxtafacet cysts, synovial and ganglion cysts, emanate from the facet joints. Patients with these cysts are typically asymptomatic but may rarely present with radiculopathy and/or myelopathy. Case Description: A 72-year-old female presented with a 1-month history of progressive lower extremity weakness (left more than right), numbness, and urinary incontinence. Notably, she also had a C7 sensory level to pin appreciation of 1-month duration. The magnetic resonance imaging showed an extradural C7 cystic lesion whose capsule enhanced with gadolinium, causing severe cord compression. The patient underwent a left C7 hemilaminectomy for complete excision of the cyst; postoperatively in 2-weeks duration, she regained full neurological function. The final histopathology was consistent with a ganglion cyst. Conclusion: Cervical juxtafacet cysts rarely cause compressive myelopathy. They may be readily diagnosed and resected with excellent postoperative outcomes.

Hydropulsion as Palliative, Long-Term, Last-Resort Treatment of Nasal Carcinoma in a Dog and a Cat

2019 ◽  
Vol 55 (5) ◽  
Author(s):  
Tom Bienes ◽  
Elisabeth Robin ◽  
Kevin Le Boedec
Keyword(s):  
Clinical Signs ◽  
Clinical Relapse ◽  
Cuff Inflation ◽  
Endotracheal Tube Cuff ◽  
Term Survival ◽  
Sterile Saline ◽  
Nasal Tumors ◽  
History Of ◽  
Nasal Carcinoma

ABSTRACT An 8 yr old spayed female domestic shorthair and an 8 yr old neutered male Polish Lowland sheepdog were evaluated for a 3 wk history of sneezing and a 5 day history of left epistaxis, respectively. In both cases, computed tomography revealed a voluminous nasal mass, which was later histologically identified as carcinoma, without cribriform plate involvement. Nasal hydropulsion was performed in both animals in sternal recumbency under general anesthesia. A Poole suction tip was inserted into the orad esophageal opening and adequacy of the endotracheal tube cuff inflation was checked. Sterile saline was forcefully infused into the obstructed nasal cavity to dislodge the tumor. Both patients had temporary resolution of clinical signs. Nasal hydropulsion was repeated as a palliative last-resort treatment at each clinical relapse (four times in both animals over ≥1 yr), allowing long-term survival. Minor complications included a self-limiting retrobulbar and oropharyngeal swelling in the cat and self-limiting epistaxis in both animals. Although this technique is not intended to represent an equivalent alternative to radiation or surgical therapies, nasal hydropulsion may represent an appropriate palliative, last-resort treatment in case of obstructive nasal tumors in dogs and cats, when radiation therapy or surgery is not affordable, available, or desired.

scholarly journals Isolation of the anaerobic intestinal spirochaete Brachyspira pilosicoli from long-term residents and Indonesian visitors to Perth, Western Australia

2009 ◽  
Vol 58 (2) ◽  
pp. 248-252 ◽  
Author(s):  
K. Rini Margawani ◽  
Ian D. Robertson ◽  
David J. Hampson
Keyword(s):  
Western Australia ◽  
Gastrointestinal Disease ◽  
Clinical Signs ◽  
Pathogenic Potential ◽  
Brachyspira Pilosicoli ◽  
Faecal Samples ◽  
History Of ◽  
The City ◽  
Culture Positive

Brachyspira pilosicoli is an anaerobic spirochaete that colonizes the large intestine of humans and various species of animals and birds. The spirochaete is an important enteric pathogen of pigs and poultry, but its pathogenic potential in humans is less clear. In the current study, the occurrence of B. pilosicoli in faecal samples from 766 individuals in two different population groups in Perth, Western Australia, was investigated by selective anaerobic culture. Of 586 individuals who were long-term residents of Perth, including children, elderly patients in care and in hospital and individuals with gastrointestinal disease, only one was culture positive. This person had a history of diverticulitis. In comparison, faeces from 17 of 180 (9.4 %) Indonesians who were short- or medium-term visitors to Perth were positive for B. pilosicoli. The culture-positive individuals had been in the city for between 10 days and 4.5 years (median 5 months). Resampling of subsets of the Indonesians indicated that all negative people remained negative and that some positive individuals remained positive after 5 months. Two individuals had pairs of isolates recovered after 4 and 5 months that had the same PFGE types, whilst another individual had isolates with two different PFGE types that were identified 2 months apart. Individuals who were culture-positive were likely to have been either colonized in Indonesia before arriving in Perth or infected in Perth following contact with other culture-positive Indonesians with whom they socialized. Colonization with B. pilosicoli was not significantly associated with clinical signs at the time the individuals were tested, although faeces with wet-clay consistency were 1.5 times more likely (confidence interval 0.55–4.6) than normal faeces to contain B. pilosicoli.

scholarly journals Successful Long-Term Use of Itraconazole for the Treatment ofAspergillusDiskospondylitis in a Dog

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Emiko Van Wie ◽  
Annie V. Chen ◽  
Stephanie A. Thomovsky ◽  
Russell L. Tucker
Keyword(s):  
Thoracolumbar Spine ◽  
Clinical Signs ◽  
Positive Culture ◽  
Spinal Pain ◽  
Intervertebral Disk ◽  
Resonance Imaging ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
History Of

A 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness. Neurologic examination revealed mild paraparesis with multifocal spinal pain. Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the thoracolumbar spine. Biopsy of the intervertebral disk at L6-7 revealed a positive culture forAspergillusspecies, and the dog was placed on itraconazole indefinitely. Clinical signs were significantly improved after two weeks of itraconazole. The dog was reevaluated 8 years later for unrelated reasons. No spinal pain was detected. Spinal radiographs revealed a fused L6-7 disk space and collapsed and sclerotic disk spaces at multiple sites. Itraconazole was tolerated by the dog with normal yearly liver enzyme values. To our knowledge, this is the first reported case of successful long-term use of itraconazole for the treatment ofAspergillusdiskospondylitis in a dog.

Surgical Treatment of Suspected Meningioangiomatosis in the Thoracolumbar Spinal Cord

2020 ◽  
Vol 56 (4) ◽  
Author(s):  
Marie C. Dantio ◽  
Amanda J. Dennis ◽  
Robert L. Bergman
Keyword(s):  
Computed Tomography ◽  
Hind Limb ◽  
Clinical Signs ◽  
Initial Examination ◽  
Limb Ataxia ◽  
Vascular Proliferation ◽  
History Of ◽  
Pelvic Limb ◽  
Long Term Prognosis

ABSTRACT A 5 yr old male neutered Labrador retriever was evaluated for an 8 wk history of a slowly progressive abnormal hind limb gait that did not respond to treatment with nonsteroidal anti-inflammatories. Initial examination findings were mild pelvic limb ataxia and moderate right pelvic limb lameness. A computed tomography with a myelogram was performed and showed a suspected intramedullary spinal mass. MRI was conducted and supported the computed tomography with myelogram findings of a possible intradural spinal mass at L1. A left-sided hemilaminectomy followed by a durotomy at L1 was performed and a firm, tan mass was removed. The histopathologic findings indicated a vascular proliferation most suggestive of a rare proliferative disorder of leptomeningeal blood vessels termed meningioangiomatosis. Although the dog’s signs initially worsened after surgery and he was nonambulatory with marked paraparesis, he regained ambulation within 3–4 wk after the operation. Eighteen months after surgery, he was ambulatory with mild hind limb ataxia with no progression of signs. This case suggests that surgical resection of lesions of suspected meningioangiomatosis can result in improvement of clinical signs with a good long-term prognosis.

The relationship between relapse, impairment and disability in multiple sclerosis

2011 ◽  
Vol 17 (10) ◽  
pp. 1218-1224 ◽  
Author(s):  
L Bennetto ◽  
J Burrow ◽  
H Sakai ◽  
J Cobby ◽  
NP Robertson ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Signs ◽  
Spatial Relationship ◽  
Afferent Pathways ◽  
Motor Pathways ◽  
Disability Status ◽  
Natural History Studies ◽  
History Of ◽  
The Relationship

Objective: To describe the spatial relationship between relapse and disability in multiple sclerosis (MS). Methods: 141 relapse onset MS patients were studied. For each patient an examination was performed and a relapse history obtained. Multivariate logistic regression examined whether there was an association between localizing clinical signs and a history of relevant relapse in order to explore the spatial relationship between relapse and subsequent disability. Results: The presence of impaired vision or sensation was independently associated with a history of one or more anatomically related relapses. The presence of weakness or cerebellar ataxia in a limb was not associated with a single relevant relapse but was associated with multiple relevant relapses. A history of multiple episodes of weakness or ataxia in the same limb was uncommon. Conclusions: Our data suggest that motor pathways are relatively resistant to chronic impairment from acute relapse, whereas afferent pathways are more susceptible. This, in combination with prominent usage of the Expanded Disability Status Scale, which is dependent on mobility and motor function at higher scores, may explain the paradox between natural history studies that suggest relapses are irrelevant to long-term disability and shorter studies at lower disability levels suggesting relapses are responsible for disability accumulation.

scholarly journals Evidence of SARS-CoV-2 transcriptional activity in cardiomyocytes of COVID-19 patients without clinical signs of cardiac involvement

2020 ◽  
Author(s):  
Gaetano Pietro Bulfamante ◽  
Gianluca Lorenzo Perrucci ◽  
Monica Falleni ◽  
Elena Sommariva ◽  
Delfina Tosi ◽  
...  
Keyword(s):  
Cardiac Involvement ◽  
Clinical Signs ◽  
Inflammatory Cells ◽  
Digital Pcr ◽  
Heart Tissue ◽  
Cardiac Phenotype ◽  
Transmission Electron ◽  
History Of ◽  
Novel Coronavirus

Background - Cardiovascular complication in patients affected by novel Coronavirus respiratory disease (COVID-19) are increasingly recognized. However, although a cardiac tropism of SARS-CoV-2 for inflammatory cells in autopsy heart samples of COVID-19 patients has been reported, the presence of the virus in cardiomyocytes has not been documented yet. Methods - We investigated for SARS-CoV-2 presence in heart tissue autopsies of 6 consecutive COVID-19 patients deceased for respiratory failure showing no signs of cardiac involvement and with no history of heart disease. Cardiac autopsy samples were analysed by digital PCR, Western blot, immunohistochemistry, immunofluorescence, RNAScope, and transmission electron microscopy assays. Results - The presence of SARS-CoV-2 into cardiomyocytes was invariably detected. A variable pattern of cardiomyocytes injury was observed, spanning from the absence of cell death and subcellular alterations hallmarks to the intracellular oedema and sarcomere ruptures. In addition, we found active viral transcription in cardiomyocytes, by detecting both sense and antisense SARS-CoV-2 spike RNA. Conclusions - In this analysis of autopsy cases, the presence of SARS-CoV-2 into cardiomyocytes, determining variable patterns of intracellular involvement, has been documented. All these findings suggest the need of a cardiologic surveillance even in survived COVID-19 patients not displaying a cardiac phenotype, in order to monitor potential long-term cardiac sequelae.

Cauda equina syndrome treated by lumbosacral stabilisation in a cat

2008 ◽  
Vol 21 (05) ◽  
pp. 462-466 ◽  
Author(s):  
M. P. Cariou ◽  
A. F. Petite ◽  
R. M. Rayward ◽  
C. K. Störk
Keyword(s):  
Cauda Equina Syndrome ◽  
Cauda Equina ◽  
Clinical Signs ◽  
Original Method ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Radiographic Findings ◽  
History Of ◽  
Pelvic Limb

SummaryIn this case report, a case of cauda equina syndrome arising from lumbosacral disease in an eight-year-old Burmese cat is described. The cat had a history of chronic right pelvic limb lameness. Neurological evaluation was consistent with a lesion involving the cauda equina. Radiographic findings were consistent with a diagnosis of lumbosacral disease. Due to perceived dorsoventral lumbosacral instability, dorsal decompression and stabilisation of the lumbosacral junction was performed. An original method of spinal stabilisation for this indication is described. The cat had a successful long-term outcome with complete resolution of its presenting clinical signs.

MRI findings and surgical treatment of a carpal synovial cyst in a dog

2020 ◽  
Vol 8 (2) ◽  
pp. e001059
Author(s):  
Caitlin Tzounos ◽  
Olivier Taeymans ◽  
Rob Quinn ◽  
Georg Haimel
Keyword(s):  
Clinical Signs ◽  
Surgical Excision ◽  
Synovial Cyst ◽  
Joint Space ◽  
Mri Findings ◽  
Thoracic Limb ◽  
History Of ◽  
Mri Characteristics

A male neutered pug aged 3 years and 3 months presented with a 4-month history of persistent left thoracic limb lameness, which was associated with a firm swelling on the palmerolateral aspect of the carpus. MRI confirmed a fluid-filled structure, which appeared to be associated with the joint space. The structure was surgically excised. Histopathology confirmed a true synovial cyst. Follow-up by telephone and email with the owner 18 months after surgery confirmed the patient was clinically well, with complete resolution of the lameness and no recurrence of swelling. This report discusses the MRI characteristics and successful treatment of a carpal synovial cyst causing lameness in the absence of osteoarthritis. There was long-term resolution of clinical signs with surgical excision of the cyst.

scholarly journals Thoracic spine metastasis presenting 18 years after complete resection of a phaeochromocytoma

2019 ◽  
Vol 12 (8) ◽  
pp. e229621
Author(s):  
Lúcia Fadiga ◽  
Joana Saraiva ◽  
Isabel Paiva ◽  
Francisco Carrilho
Keyword(s):  
Neuroendocrine Tumours ◽  
External Beam Radiotherapy ◽  
Primary Tumour ◽  
Hypertensive Crisis ◽  
Cord Compression ◽  
Ct Guided ◽  
Ct Guided Biopsy ◽  
History Of ◽  
Iodine 131

Phaeochromocytomas are rare neuroendocrine tumours (NET) with malignant behaviour in about 10% of cases. The median time from the diagnosis of primary tumour and bone metastasis is 3.4 years. We report a case of a 66-year-old woman presenting with a hypertensive crisis and back pain. She has a history of a phaeochromocytoma completely resected 18 years before. MRI showed a neoplastic mass on the 10th thoracic vertebra (T10), with fracture and spinal cord compression. The CT-guided biopsy was consistent with metastasis of a NET. Therefore, she was treated with phenoxybenzamine and external beam radiotherapy. However, clinical (dorsal pain) and biochemical (ie, elevated chromogranin A) signs suggested persistent disease and the patient was treated with iodine-131 metaiodobenzylguanidine and T10 kyphoplasty. After 8 years, she remains clinically stable. This case demonstrates that phaeochromocytomas may reveal malignant behaviour several years after diagnosis, and therefore patients should be maintained under long term surveillance.

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