scholarly journals Assessment of Bone Mineral Density in Patients Undergoing Hemodialysis; An Iranian Population-Based Study

2021 ◽  
Vol 24 (8) ◽  
pp. 599-606
Author(s):  
Saeid Amirkhanlou ◽  
Gholamreza Roshandel ◽  
Mehrdad Aghaei ◽  
Hossein Mohebi ◽  
Sahab-Sadat Tabatabei ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Density ◽  
Bone Mineral ◽  
Mass Density ◽  
Population Based ◽  
Cross Sectional Study ◽  
Bone Mass Density ◽  
Mineral Density ◽  
Cross Sectional ◽  
Low Bone Density

Background: End-stage renal disease (ESRD) is a condition in which bone turnover and metabolism is impaired; thus, osteoporosis and low bone density are subsequently inevitable. We aimed to determine bone mineral density (BMD) and biochemical markers, and associated factors in hemodialysis (HD) patients. Methods: Patients aged 30-70 years undergoing HD between 2015 to 2019 were enrolled in this cross-sectional study. BMD measured by dual energy x-ray absorptiometry (DEXA) and biochemical laboratory tests were assessed in 200 patients undergoing HD. Statistical analysis was based on t test, Pearson, regression and Mann-Whitney tests using SPSS 16. Results: Two hundred patients were investigated. Sixty percent of the patients were female. Mean ± SD of participants’ age was 58.6 (±11.63) years and mean ± SD for duration of HD was 45.69 (± 43.76) months. Osteoporosis was found in 48% (n=96) and low bone density in 36% (n=76) of our patients. General osteoporosis was more frequent in those undergoing HD for more than 3 years, although not significantly (P=0.093, odds ratio [OR]=0.37). However, regional osteoporosis in hip and femoral neck, but not spine vertebrae, were significantly higher after three years of HD (P=0.036, OR=0.27; P=0.042, OR=0.27; and P=0.344, OR=0.56, respectively). Increased body mass index (BMI) correlated negatively with osteoporosis (P=0.050). Conclusion: With increasing age and duration of HD, BMD decreases. Higher BMI was associated with higher bone mass density. Bone density assessment seems to be necessary in patients undergoing HD.

scholarly journals Densitas Massa Tulang pada Pasien HIV/AIDS

2017 ◽  
Vol 3 (4) ◽  
pp. 200
Author(s):  
Nadia Ayu Mulansari ◽  
Nanang Sukmana ◽  
Bambang Setyohadi ◽  
Siti Setiati
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Mass Density ◽  
Bone Mass Density ◽  
Mineral Density ◽  
Cross Sectional ◽  
Keywords Hiv ◽  
Hiv Seropositive ◽  
Hiv Aids

Pendahuluan. Tingginya angka kejadian HIV/AIDS pada usia muda yang mencapai 50% dari total kasus HIV/AIDS di Indonesia menjadi permasalahan yang serius, khususnya terkait kualitas hidup pasien. Selain infeksi oportunistik, keadaan osteopenia dan juga osteoporosis sering ditemukan pada pasien dengan HIV/AIDS. Namun demikian, penelitian mengenai gambaran massa tulang pada pasien HIV/AIDS di Indonesia sampai saat ini belum didapatkan.Metode. Studi potong lintang dilakukan pada pasien dewasa dengan infeksi HIV naif antiretroviral di Rumah Sakit dr. Cipto Mangunkusumo (RSCM) Jakarta pada Februari-Mei 2008. Pemeriksaan bone mineral density (BMD) dilakukan dengan menggunakan DXA scanning. Hasil. Berdasarkan pemeriksaan BMD didapatkan sebanyak 29,3% subjek ostopenia, 1,3% osteoporosis dan sisanya normal. Osteopenia/osteoporosis didapatkan lebih besar pada subjek yang mengonsumsi alkohol, merokok, hitung limfosit CD4+ <200 sel/mm3 dan IMT<18,5 dengan proporsi masing-masing secara berturut-turut yaitu 53,6%; 36,9%; 35,5%; dan 37,6%. Lama infeksi HIV pada penelitian ini tidak menunjukkan hasil yang berbeda.Simpulan. Didapatkan keadaan osteopenia dan osteoporosis pada pasien dengan HIV/AIDS. Pada pasien HIV/AIDS dengan riwayat merokok, konsumsi alkohol, hitung limfosit CD4+ <200 sel/mm3 dam IMT rendah, didapatkan angka osteopenia/osteoporosis yang lebih tinggi.Kata kunci: HIV, naif antiretroviral, osteopenia/osteoporosis Bone Mass Density in HIV/AIDS PatientsIntroduction. Indonesia has a high incidence of young HIV-positive population which is 20-29 years of age is in the highest group (50%). For this reason, it is important to make a better quality of life for them. Unfortunately, beside all the opportunistic infection, it was proved that osteopenia/osteoporosis has become a new emerging metabolic condition for HIV-infected patients. There is still no study about the description of bone mass density in HIV/AIDS patients in Indonesia. Methods. A cross sectional study was conducted in a total of 75 HIV-seropositive antiretroviral-naïve patients. Bone mineral density (BMD) was determined by dual energy X-ray absorptiometry in lumbar spine. Results. Seventy-five subjects had been recruited. Low BMD was found in 29.3% HIV-seropositive patients with osteopenia and 1,3% with osteoporosis. There was a higher number of osteopenia/osteoporosis in subjects who consume alcohol, smoking, lymphocyte CD4 <200 cells/mm3 and low body mass index (BMI). Duration of infection did not show any differences in both HIV with osteopenia/osteoporosis and subjects with normal bone condition. Conclusions. Osteopenia and osteoporosis were found in patients with HIV/AIDS in RSCM with lower bone density in subjects who consumed alcohol, smoke, lymphocyte CD4 <200 cells/mm3 and low BMI. Keywords: HIV, antiretroviral naïve, osteopenia/osteoporosis 

Association between reproductive factors and postmenopausal osteoporosis

2011 ◽  
Vol 20 (03) ◽  
pp. 248-251
Author(s):  
H. R. Meybodi ◽  
N. Khalili ◽  
P. Khashayar ◽  
R. Heshmat ◽  
A. Hossein-nezhad ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Reproductive Factors ◽  
Population Based ◽  
Age At Menarche ◽  
Mineral Density ◽  
Cross Sectional ◽  
Number Of Children ◽  
Menstrual History ◽  
Duration Of Breastfeeding

SummaryThe present cross-sectional research was designed to study possible correlations between clinical reproductive factors and bone mineral density (BMD) values.Using the data gathered by the population-based Iranian Multicenter Osteoporosis Study (IMOS), we investigated the correlation found between reproductive factors and osteoporosis. Subjects were recruited from five major cities of Iran. Bone mineral density was measured using Dual-Energy X-ray Absorptiometry and the results were analyzed against the age at menarche and at menopause, number of pregnancies, children and abortions, and the history (and duration) of breastfeeding.Data was available for 2528 women. Gravidity and number of children were reversely correlated with BMD. Younger age at menarche was associated with higher BMD values, whereas there was no significant correlation between age at menopause and menstrual history and BMD.Our study suggests that clinical reproductive factors, particularly number of children and breastfeeding, could be incorporated as predictors of BMD levels in women. Given the controversial results obtained in different studies, longitudinal studies should be carried out to enlighten the importance of these factors and the rationale of their use to predict BMD values in different settings.

scholarly journals Somatic maturation and the relationship between bone mineral variables and types of sports among adolescents: cross-sectional study

2017 ◽  
Vol 135 (3) ◽  
pp. 253-259 ◽  
Author(s):  
Ricardo Ribeiro Agostinete ◽  
Igor Hideki Ito ◽  
Han Kemper ◽  
Carlos Marcelo Pastre ◽  
Mário Antônio Rodrigues-Júnior ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Peak Height ◽  
Cross Sectional Study ◽  
Height Velocity ◽  
Whole Body ◽  
Sectional Study ◽  
Peak Height Velocity ◽  
Mineral Density ◽  
Cross Sectional

ABSTRACT CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS: The study was composed of 93 adolescents (12 to 16.5 years old), divided into three groups: no-sport group (n = 42), soccer/basketball group (n = 26) and swimming group (n = 25). Bone mineral density and content were measured using dual-energy x-ray absorptiometry and somatic maturation was estimated through using peak height velocity. Data on training load were provided by the coaches. RESULTS: Adolescents whose PHV occurred at an older age presented higher bone mineral density in their upper limbs (P = 0.018). After adjustments for confounders, such as somatic maturation, the swimmers presented lower values for bone mineral density in their lower limbs, spine and whole body. Only the bone mineral density in the upper limbs was similar between the groups. There was a negative relationship between whole-body bone mineral content and the weekly training hours (β: -1563.967; 95% confidence interval, CI: -2916.484 to -211.450). CONCLUSION: The differences in bone variables attributed to sport practice occurred independently of maturation, while high training load in situations of hypogravity seemed to be related to lower bone mass in swimmers.

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