scholarly journals DEVELOPMENT OF A BIODEGRADABLE MATERIAL FOR BONE REGENERATION BASED ON SILICON COMPOUNDS

2021 ◽  
Vol 11 (2) ◽  
pp. 98-100
Author(s):  
Dmitry Kompantsev ◽  
Anna Chahirova ◽  
Ruslan Yusupov ◽  
Ilya Zaharchanko ◽  
Natalia Shabanova
Keyword(s):  
Bone Tissue ◽  
Cortical Plate ◽  
Biodegradable Material ◽  
Laboratory Sample ◽  
Artificial Defect ◽  
Bone Material ◽  
Silicon Compounds ◽  
Defect Zone ◽  
Complete Restoration ◽  
High Degree

In the course of this study we established that the laboratory sample in granulated form developed by us has a stimulating effect on the growth and proliferation of osteoblasts. Analysis of the data (CT, MRI) of the biological material obtained from the animals withdrawn from the experiment showed a statistically significant replacement of the artificial defect with bone tissue with signs of restoration of the cortical plate. The analysis of the CT results indicates that this method is sufficiently informative in assessing the regeneration of the trabecular structure of bone tissue. The study (MRI) of the bone material obtained from the animals participating in the experiment showed that when the osteoinductive material was integrated, the defect zone was replaced by 90%. In the projection of the defect, the newly formed tissue of a homogeneous structure was determined, corresponding in density to bone tissue with a high degree of mineralization. There was a complete restoration of bone tissue in the projection of the defect.

scholarly journals MODERN METHODS OF DIAGNOSIS OF POST PROSTHETIC COMPLICATIONS DURING DENTAL IMPLANTATION

2020 ◽  
Vol 74 (2) ◽  
pp. 72-76
Author(s):  
D.V. Mikhalchenko ◽  
◽  
Yu.A. Makedonova ◽  
Kh.Yu. Salyamov ◽  
◽  
...  
Keyword(s):  
Early Detection ◽  
Bone Tissue ◽  
Early Period ◽  
Cortical Plate ◽  
Frequency Of Occurrence ◽  
Timely Manner ◽  
Diagnostic Measures ◽  
Dental Implantation ◽  
Modern Methods ◽  
Prosthetic Complications

The number of dental implants performed at the dental reception is steadily increasing. Along with this increased and the frequency of occurrence postprostatectomy complications in dental implantation. One of the main tasks of a dentist is early detection of the initial signs of inflammation of the parotid tissue, leading to mucositis. If you do not act on the site of inflammation in a timely manner, the destruction of bone tissue around the implant will begin with the development of peri-implantitis. In this work, we conducted a retrospective analysis of the frequency of occurrence of mucositis and periimplantitis. An algorithm for diagnostic measures has been developed. The patients were determined by the hygienic index, the iodine number of Svrakov, the degree of bleeding, and the depth of probing of the dental sulcus. The implant stabilization was determined using amplitude-frequency analysis. A detailed periodontal screening was performed to assess the condition of the gums and identify pathological processes occurring in the tissue surrounding the implants. The condition of the cortical plate and parotid bone tissue was evaluated radiologically. The developed algorithm for diagnostic examination of patients with postprotetic complications during dental implantation helps to detect inflammation in an early period, which in turn allows to preserve the integrity of the tooth.

EXPERIMENTAL STUDY ON THE EFFECT OF DRILL QUALITY ON BONE TEMPERATURE IN DRILLING

2018 ◽  
Vol 30 (02) ◽  
pp. 1850018 ◽  
Author(s):  
Khurshid Alam ◽  
Syed Husain Imran ◽  
Abdullah Al-Shabibi ◽  
Mojtaba Ghodsi ◽  
Vadim Silberschmidth
Keyword(s):  
Experimental Study ◽  
Bone Tissue ◽  
Femoral Shaft ◽  
Tissue Temperature ◽  
Bone Drilling ◽  
Thermal Necrosis ◽  
Bone Material ◽  
Rate Of Penetration ◽  
Lower Temperature ◽  
Drilling Conditions

Bone drilling is widely performed in orthopedics for fixation and reconstruction of bone. In bone drilling, a hard metallic drill penetrates into the bone tissue which may cause trauma. Shear deformation of the bone material and friction between the drill and bone may induce elevated temperature in bone tissue. Temperature above a certain level may seriously harm the tissue, leading to several postoperative complications. The purpose of the current study is to measure and compare temperature in bone drilling using sharp and worn drill. Drilling tests were performed on cortical bone obtained from femoral shaft of a cow. A parametric study was conducted to quantify bone temperature using a range of drilling speeds and feed rates using drills having sharp and worn cutting edges with and without cooling environment. The temperature was measured using thermocouples, and wear of the cutting edges of the drill was measured using a scanning profilometer. Experimental results demonstrated lower temperature in bone using a sharp drill compared with a worn drill for similar drilling conditions. The bone temperature was found to rise with drill rotational speed, rate of penetration and size of the drill with and without cooling. Blunt drills were found more crucial for inducing thermal necrosis in bone.

scholarly journals Studies on bone enzymes. The activation and release of latent acid hydrolases and catalase in bone-tissue homogenates

1965 ◽  
Vol 97 (2) ◽  
pp. 393-402 ◽  
Author(s):  
G Vaes
Keyword(s):  
Osmotic Pressure ◽  
Bone Tissue ◽  
Total Activity ◽  
Acid Hydrolases ◽  
Freezing And Thawing ◽  
Physical Heterogeneity ◽  
Tissue Homogenates ◽  
Triton X ◽  
High Degree ◽  
Parallel Fashion

1. Eight distinct acid-hydrolase activities present in cytoplasmic extracts from bone tissue occur in latent form to the extent of 50-70% of their total activity, depending on the enzyme. 2. This latency can be decreased or suppressed by exposure to Triton X-100 or to media of low osmotic pressure, by treatment in the Waring Blendor, and by freezing and thawing, but not by increasing the substrate concentration in the assay medium up to 10-fold the Michaelis constant of the enzymes. 3. Latency is the property of the particle-bound enzymes, and treatments that suppress latency simultaneously cause solubilization of the enzymes. Most enzymes show an excess of free over soluble activity; the magnitude of this excess seems to depend largely on the nature of the enzyme, and sometimes also on the kind of treatment suffered by the preparations; it is attributed mainly to adsorption artifacts. 4. In preparations subjected to graded activating treatments, seven of the eight acid hydrolases studied are released in closely parallel fashion, suggesting that they are associated with particles possessing similar properties. Acid phenylphosphatase is released less readily than the other enzymes by Triton X-100 and by exposure to media of low osmotic pressure. 5. It is concluded from these and previous published fractionation experiments that, with the possible exception of part of the acid-phenylphosphatase activity, the eight acid hydrolases studied belong to lysosome-like particles. Bone lysosomes exhibit a relatively high degree of biochemical and physical heterogeneity. Their possible functions are discussed. Part of the acid-phenylphosphatase activity could be linked to another group of particles. 6. Catalase is also partly (30%) latent in cytoplasmic extracts of bone. Latent catalase can be released by some of the treatments that suppress the latency of the lysosomal enzymes, but differs from the latter by a greater resistance to Triton X-100, and, especially, by a complete insensitivity to exposure to media of low osmotic pressure. It is concluded from these results that the catalase-containing particles are probably different from lysosomes, as they are in liver. 7. Cytochrome oxidase, which is presumably associated with the mitochondria, and alkaline phenylphosphatase, an enzyme occurring predominantly in the microsomal fraction, exhibited no latency under the conditions of the present experiments.

scholarly journals Анализ распределения антропологических материалов (костей посткраниального скелета) по курганным группам

2020 ◽  
Vol 15 (3) ◽  
pp. 10-25
Author(s):  
Lyubov’ A. Bembeeva ◽  
Keyword(s):  
Bone Tissue ◽  
Field Studies ◽  
Soil Characteristics ◽  
Postcranial Skeleton ◽  
Scientific Center ◽  
Bone Material ◽  
The Republic

The article deals with the results of the distribution of the anthropological materials, namely bones of postcranial skeleton. Due to the great amount of material, the cranial part of the collection will be analyzed separately. In the process of cataloging of the bone material kept at the depository of the Kalmyk Scientific Center of the RAS, there is the need for paying a special attention to the distribution of the existing anthropological materials into different mound groups, which were located in different landscape-geographical zones of the Republic of Kalmykia. The special attention was given to the representation of the anthropological unit (which exactly skeleton bones) and also the integrity of the bone tissue. This criterion is important for the evaluation of the influence of soil characteristics on the integrity of the mineral and organic parts of the bones. The cultural-chronological belonging of the anthropological material in question is given in a general way on the basis of field studies reports.

Is Retrieval of Bone Material From Multiorgan Donors Effective Enough to Cover Demand for Biostatic Bone Tissue Grafts in Poland?

2006 ◽  
Vol 38 (1) ◽  
pp. 297-300 ◽  
Author(s):  
A. Bohatyrewicz ◽  
R. Bohatyrewicz ◽  
K. Dobiecki ◽  
D. Kotrych ◽  
A. Kamiński ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Bone Material ◽  
Tissue Grafts

scholarly journals The use of numerical models as a modern tool in fire investigation

2020 ◽  
Vol 305 ◽  
pp. 00084
Author(s):  
Marius Cornel Şuvar ◽  
Laurenţiu Munteanu ◽  
Aurelian Nicola
Keyword(s):  
Computer Simulations ◽  
Current Practice ◽  
Numerical Models ◽  
Fire Investigation ◽  
Laboratory Sample ◽  
In Fire ◽  
High Degree ◽  
Modern Tool ◽  
Complex Activities

Investigating the fire type events is characterized by a high degree of complexity, due to the fact that it has to find answers to aspects coming from multidisciplinary fields: technical-scientific, legal, organizational, psychological, etc. The management of the findings, the analyzed samples, and the resulting data implies a series of complex activities, based on the use of advanced procedures and techniques. Fire investigation aims to determine the source of ignition and all the components that contribute to define the cause of the fire, to assess the motivations of the involved persons and to decipher the mechanism of heat transfer or burning processes that describes the propagation and development of a fire. Often, in order to understand the mechanism of the pyrogenic phenomenon, the following approaches are used in the current practice: technical-scientific expertises, reconstruction of the event on the field or in the laboratory, sample analysis, and, last but not least, computer simulations. This paper aims to highlight the role of the numerical models used in the field of fire safety, respectively in the elaboration of the post-event, technical-scientific expertises, by presenting some results obtained from the computer simulations, used to substantiate the fire mechanism and to formulate the conclusions.

scholarly journals EXPERIMENTAL STUDY OF INTEGRATION FEATURES OF POROUS PERMEABLE AND MESH TITANIUM NICKELIDE IN VIVO

2020 ◽  
pp. 434-439
Author(s):  
M.SH. MIRZOEV ◽  
◽  
M.N. SHAKIROV ◽  
E.D. POROKHOVA ◽  
R.N. DZHONIBEKOVA ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Titanium Nickelide ◽  
Digital Camera ◽  
Optimal Growth ◽  
Artificial Defect ◽  
Combined Use ◽  
Bone Structures ◽  
Keywords Bone Defect ◽  
Defective Bone

Objective: Morphological assessment of the integration features of the combined use of porous permeable and textile mesh titanium nickelide with bone structures of the recipient zone. Methods: The study was carried out on 20 Chinchilla rabbits of both sexes at the age of 1-1.5 years with a bodyweight of 2500-4000 g. In animals, the artificial defect was created in one of the areas of the lower jaw, where a porous permeable titanium nickelide was installed, wrapped in a textile mesh version of it was installed. Animals were removed from the experiment for 30, 90, 180, and 360 days of research via intraperitoneal injection of mortal dose 1% solution thiopental sodium. The material for histological research was fixed in 10% buffered formalin during 12 hours after then washed with water and decalcified. The prepared sections were stained with hematoxylin-eosin. Microscopic examination of the stained preparations and photography were carried out using a light microscope Axioscope 40 (Zeiss, Germany) via a digital camera (Canon, Japan). Results: Studies have shown that with the combined use of porous permeable and textile mesh titanium nickelide, the artificially created defects of the mandibula between both contacting surfaces are formed directly, which leads to stable fixing. The porous structure of the material, its hysteresis behavior with organism tissues, provides widespread regeneration of cells and formed a homogeneous mature bone tissue bone tissue, both in the pores and around the structure. Conclusions: These and other facts indicate the high integration properties of the material that is investigated, which ensures optimal growth and population of osteogenic cells in the vicinity of defective bone areas in a growing organism. Keywords: Bone defect, osteointegration, regeneration, titanium nickelide, porous permeable implant.

scholarly journals COMPARATIVE EPR SPECTROSCOPY OF MEAT AND FISH RAW MATERIALS

2018 ◽  
pp. 75-82
Author(s):  
R. T. Timakova
Keyword(s):  
Bone Tissue ◽  
Epr Spectroscopy ◽  
Raw Materials ◽  
Fish Skin ◽  
Irradiated Food ◽  
Epr Signal ◽  
Irradiated Meat ◽  
High Degree

The spread of radiation technologies requires the control of irradiated food raw materials.The possibility of identification of irradiated meat and fish raw materials by bone and pulp tissues, for fish raw materials also by skin with scales has been Experimentally established. The area of the EPR signal of samples of bone tissue in meat raw materials and samples of scales from the fish skin the raw materials most sensitive to amplitude variations with a high degree of correlation (up to 0.99).

scholarly journals Features of the approach to orthodontic treatment of patients taking into account the periodontal biotype

2020 ◽  
pp. 10-13
Author(s):  
Y. P. Bolovina ◽  
V. M. Vologina ◽  
F. Ibrahem
Keyword(s):  
Bone Tissue ◽  
Orthodontic Treatment ◽  
Selective Extraction ◽  
Cortical Plate ◽  
Alveolar Ridge ◽  
Treatment Methods ◽  
Periodontal Tissues ◽  
Periodontal Biotype

A feature of periodontal anatomy, in which the proximity of the roots of the teeth to the cortical plates or the sections of the roots of the teeth is determined and that are not included in the bone tissue, contributes to the onset of gum recession or its progression during or after orthodontic treatment. When teeth move towards the cortical plate, it can be destroyed. At the same time, teeth moving towards the center of alveolar ridge often causes the formation of bone tissue from the vestibular side that contributes to the improvement of fixing ability of the periodontium. In case when oral vestibular size of the roots of the teeth exceeds the volume of periodontal tissues, orthodontists use treatment methods that contribute to creating space within the dentition without changing its size: grinding of approximate surfaces and selective extraction of teeth. Knowing and considering periodontal biotypes, clinicians can predict the course of treatment, apply appropriate methods of orthodontic benefits to minimize alveolar resorption and ensure favorable results.

scholarly journals Magnetomechanical stimulation of bone tissue regeneration

2021 ◽  
pp. 90-93
Author(s):  
G.S. Zamay ◽  
◽  
O.S. Kolovskaya ◽  
D.S. Grek ◽  
V.A. Babkin ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Low Frequency ◽  
Rgd Peptide ◽  
Superparamagnetic Nanoparticles ◽  
Bone Tissue Regeneration ◽  
Complete Restoration ◽  
Transverse Osteotomy ◽  
Tissue Recovery ◽  
Magnetic Fi Eld

The aim of the research. To assess the ability of superparamagnetic nanoparticles functionalized with the RGD peptide to accelerate bone tissue recovery aft er transverse osteotomy under the infl uence of a low-frequency alternating magnetic fi eld. Material and methods. We used superparamagnetic nanoparticles ferroarabinogalactans (FeAG) functionalized with the RGD peptide for targeted binding to integrins. Th e model for assessing the ability of FeAG-RGD to accelerate bone regeneration was the transverse osteotomy of the radius of the ICR mice. To induce the process of bone tissue regeneration aft er the injection of FeAG-RGD particles, mice were placed in an alternating magnetic fi eld (50 Hz 100 Oe) for 60 min. Th e therapy was performed daily for 5 days. Results. Th e paper tested the hypothesis about the acceleration of bone tissue regeneration by the method of magnetomechanical therapy using superparamagnetic FeAG-RGD nanoparticles. It has been established that FeAG-RGD under conditions of an alternating magnetic fi eld (50 Hz 100 Oe) are able to change their orientation in space and, thus, cause mechanical stress in the proteins of the cell membrane – integrins, which trigger the process of osteogenic diff erentiation. Th e research results showed that 5 procedures of magnetomechanical therapy lead to complete restoration of bone tissue at the site of the transverse osteotomy, while in the group of control animals no fusion of bones is observed. Conclusion. Th e use of the method of magnetomechanical therapy using ferroarabinogalactans functionalized with the targeting ligand RGD for binding to integrins of osteogenic cells is a promising technology for bone tissue regeneration

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