scholarly journals Osteomyelitis: A Literature Review

2019 ◽  
Vol 11 (2) ◽  
pp. 69
Author(s):  
Rangga Rawung ◽  
Chita Moningkey
Keyword(s):  
Literature Review ◽  
Antibiotic Therapy ◽  
Basic Principle ◽  
Treatment Strategy ◽  
Operative Techniques ◽  
Successful Management ◽  
Anatomy And Physiology ◽  
Joint Infections ◽  
Basic Understanding

Abstrak: Infeksi pada tulang dan sendi masih merupakan kasus yang menantang. Kondisi ini memberikan banyak penyulit baik kepada dokter maupun pasien. Meski terapi antibiotika dilaporkan memberikan hasil yang memuaskan pada banyak kasus infeksi, tidak demikian pada kasus infeksi tulang dan sendi. Hal ini berhubungan dengan struktur anatomi dan fisiologi dari tulang. Diperlukan sebuah strategi tata laksana yang baik untuk mencapai hasil yang optimal. Prinsip dasar yang utama dalam mencapai pengobatan yang optimal ialah penegakan diagnosis awal yang tepat, termasuk di dalamnya proses investigasi pemeriksaan mikrobiologi dan patologi. Diperlukan pengertian dasar serta pengenalan kembali anatomi, fisiologi, patofisiologi, dan tata laksana terkini tentang osteomielitis untuk mencapai tatalaksana yang optimal.Kata kunci: diagnosis dan tata laksana osteomielitisAbstract: Infection in bone and joint is still a challenging case. It gives a lot of problems and frustration to the physician and patient. The successful antibiotic therapy in most infectious diseases is abortive to achieve in bone and joint infections because the different characteristic in anatomy and physiology of these structures. Therefore, treatment strategy, including non operative and operative techniques is required to deal with such conditions. The basic principle to achieve a successful management of osteomyelitis in general is correct initial diagnosis including investigation for microbiological and pathological examinations to allow the proper and long term lasting therapy of antibiotic. For that reason, it is required to have the basic understanding in dealing with this issue, obvious and updated. It is commited to review the pathophysiology, the diagnosis, and the management of osteomyelitis in order to presents basic facilities in dealing with osteomyelitis.Keywords: osteomyelitis diagnosis and management

scholarly journals Treatment strategy for atypical ulnar fracture due to severely suppressed bone turnover caused by long-term bisphosphonate therapy: a case report and literature review

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kensaku Abe ◽  
Hiroaki Kimura ◽  
Norio Yamamoto ◽  
Shingo Shimozaki ◽  
Takashi Higuchi ◽  
...  
Keyword(s):  
Literature Review ◽  
Bone Turnover ◽  
Bone Graft ◽  
Treatment Strategy ◽  
Bisphosphonate Therapy ◽  
Bone Union ◽  
Atypical Fracture ◽  
Dual Plate ◽  
Severely Suppressed Bone Turnover

Abstract Background Atypical fractures may occur due to the combined effect of severely suppressed bone turnover (SSBT) caused by long-term bisphosphonate treatment and chronic repetitive bone microdamage. Atypical fracture of the ulna due to SSBT is a rare entity; there is no standardized treatment strategy for this condition. We successfully treated a patient with atypical fracture of the ulna. Herein, we present this patient, review the relevant literature, and discuss the treatment strategy. Case presentation An 84-year-old woman presented with atypical fracture of the left ulnar shaft due to SSBT. She had a history of bisphosphonate therapy (ibandronate and alendronate) since more than 10 years; her bone turnover was severely suppressed. We performed open reduction and internal fixation (ORIF) using dual plate with some additional treatments. These included drilling and decortication, use of autogenous bone graft, low-intensity pulsed ultrasound (LIPUS) treatment, and administration of teriparatide. Finally, bone union was observed at 11 months after surgery. Conclusions Based on the literature review and our experience with this case, ORIF alone may not be adequate to achieve bone union; drilling, decortication, and use of cancellus bone graft is important to achieve favorable outcomes. Administration of teriparatide and LIPUS may facilitate early bone union, although further studies are required to provide more definitive evidence. Furthermore, ORIF using dual plate may help avoid implant failure owing to the long time required for bone union.

scholarly journals Correction to: Treatment strategy for atypical ulnar fracture due to severely suppressed bone turnover caused by long-term bisphosphonate therapy: a case report and literature review

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kensaku Abe ◽  
Hiroaki Kimura ◽  
Norio Yamamoto ◽  
Shingo Shimozaki ◽  
Takashi Higuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Bone Turnover ◽  
Treatment Strategy ◽  
Bisphosphonate Therapy ◽  
Ulnar Fracture ◽  
Severely Suppressed Bone Turnover

An amendment to this paper has been published and can be accessed via the original article.

Extended sternoclavicular joint infections – long term results

2017 ◽  
Author(s):  
DI Trufa ◽  
W Schreiner ◽  
RE Horch ◽  
H Sirbu
Keyword(s):  
Sternoclavicular Joint ◽  
Long Term Results ◽  
Joint Infections

Generalized mycobacteriosis with secondary lesions of the spine in HIV positive patients

MedAlliance ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 54-60
Keyword(s):  
Antibiotic Therapy ◽  
Granulomatous Inflammation ◽  
Hiv Positive ◽  
Hiv Patients ◽  
Histological Picture ◽  
Clinical Observations ◽  
Spinal Lesion ◽  
Secondary Lesion

2 clinical observations of generalized forms of mycobacteriosis in HIV (+) patients complicated by secondary spinal lesion are described. Anamnestic data on the presence of mycobacteriosis of the lungs allowed to suspect a secondary lesion of the spine. Verification of the diagnosis is possible only with bacteriological confirmation, since the histological picture is nonspecific and resembles tuberculous granulomatous inflammation. Treatment of spondylitis caused by non-tuberculous mycobacteria is complex and includes both surgical rehabilitation of the focus and long-term (at least 1 year) antibiotic therapy.

scholarly journals Brain Abscess Caused by Nocardia: Case Report and Literature Review

2020 ◽  
Author(s):  
Guilherme Finger ◽  
Maria Eduarda Conte Gripa ◽  
Tiago Paczko Bozko Cecchini ◽  
Tobias Ludwig do Nascimento
Keyword(s):  
Case Report ◽  
Antibiotic Therapy ◽  
Brain Abscess ◽  
Clinical Signs ◽  
Occipital Lobe ◽  
High Morbidity ◽  
Rare Clinical Entity ◽  
Brain Abscesses

AbstractNocardia brain abscess is a rare clinical entity, accounting for 2% of all brain abscesses, associated with high morbidity and a mortality rate 3 times higher than brain abscesses caused by other bacteria. Proper investigation and treatment, characterized by a long-term antibiotic therapy, play an important role on the outcome of the patient. The authors describe a case of a patient without neurological comorbidities who developed clinical signs of right occipital lobe impairment and seizures, whose investigation demonstrated brain abscess caused by Nocardia spp. The patient was treated surgically followed by antibiotic therapy with a great outcome after 1 year of follow-up.

Persistent Multispecies Actinomyces Mastitis Treated With Repeated Aspiration and Long-Term Oral Antibiotics

2021 ◽  
pp. 000313482110257
Author(s):  
Colin Jenkins ◽  
Anand Ganapathy ◽  
Crystal Fancher ◽  
Kazuhide Matsushima
Keyword(s):  
Antibiotic Therapy ◽  
Rare Condition ◽  
Breast Abscess ◽  
Amoxicillin Clavulanic Acid ◽  
Recurrent Breast ◽  
Causative Bacterium ◽  
Repeated Aspiration ◽  
Prolonged Antibiotic Therapy

Actinomycosis is an infection characterized by abscess formation, draining sinuses, and tissue fibrosis. The causative bacterium is a Gram-positive facultative anaerobe from the genus Actinomyces. Infections classically affect the cervicofacial, thoracic, or pelvic region and often require prolonged antibiotic therapy. Actinomycosis of the breast is a rare condition that may present as a recurrent breast abscess. We present a 33-year-old female with a recurrent breast abscess which grew A. radingae and A. israeli on aspirated fluid cultures. Treatment with surgical aspiration and a 6-week course of oral amoxicillin/clavulanic acid 875 mg twice daily resulted in clinical improvement. Our case demonstrates how recurrent breast abscesses caused by Actinomyces can be difficult to manage. Long-term antibiotic therapy with surgical aspiration and regular follow-up offer the best chance of clinical resolution.

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