High-rate OVPE-GaN growth by the suppression of polycrystal formation with additional H2O vapor in a high-temperature condition

Background: Orthosiphon stamineus is a traditional medicinal plant in Southeast Asia countries with various well-known pharmacological activities such as antidiabetic, diuretics and antitumor activities. Transketolase is one of the proteins identified in the leaves of the plant and transketolase is believed able to lower blood sugar level in human through non-pancreatic mechanism. In order to understand the protein behavioral properties, 3D model of transketolase and analysis of protein structure are of obvious interest. Methods: In the present study, 3D model of transketolase was constructed and its atomic characteristics revealed. Besides, molecular dynamic simulation of the protein at 310 K and 368 K deciphered transketolase may be a thermophilic protein as the structure does not distort even at elevated temperature. This study also used the protein at 310 K and 368 K resimulated back at 310 K environment. Results: The results revealed that the protein is stable at all condition which suggest that it has high capacity to adapt at different environment not only at high temperature but also from high temperature condition to low temperature where the structure remains unchanged while retaining protein function. Conclusion: The thermostability properties of transketolase is beneficial for pharmaceutical industries as most of the drug making processes are at high temperature condition.

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Investigation Into Thermal Stress Characteristics of Pipe-in-Pipe Under High Temperature Condition

Volume 3A: Design and Analysis ◽

10.1115/pvp2018-84578 ◽

2018 ◽

Author(s):

Si-Hwa Jeong ◽

Min-Gu Won ◽

Nam-Su Huh ◽

Yun-Jae Kim ◽

Young-Jin Oh ◽

...

Keyword(s):

Heat Transfer ◽

Thermal Stress ◽

High Temperature ◽

Temperature Distribution ◽

Heat Transfer Analysis ◽

Piping System ◽

Curved Pipe ◽

High Temperature Condition ◽

Single Pipe ◽

Radiation Conditions

In this paper, the thermal stress characteristics of the pipe-in-pipe (PIP) system under high temperature condition are analyzed. The PIP is a type of pipe applied in sodium-cooled faster reactor (SFR) and has a different geometry from a single pipe. In particular, under the high temperature condition of the SFR, the high thermal stress is generated due to the temperature gradient occurring between the inner pipe and outer pipe. To investigate the thermal stress characteristics, three cases are considered according to geometry of the support. The fully constrained support and intermediate support are considered for case 1 and 2, respectively. For case 3, both supports are applied to the actual curved pipe. The finite element (FE) analyses are performed in two steps for each case. Firstly, the heat transfer analysis is carried out considering the thermal conduction, convection and radiation conditions. From the heat transfer analysis, the temperature distribution results in the piping system are obtained. Secondly, the structural analysis is performed considering the temperature distribution results and boundary conditions. Finally, the effects of the geometric characteristics on the thermal stress in the PIP system are analyzed.

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