scholarly journals Automatic Early Detection of Alzheimer‟s Disease based on 2D-VMD and Deep Convolutional Neural Network

2019 ◽  
Vol 9 (1) ◽  
pp. 6964-6969
Keyword(s):  
Neural Network ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Convolutional Neural Network ◽  
Classification Accuracy ◽  
Early Stage ◽  
Deep Convolutional Neural Network ◽  
Intrinsic Mode Functions ◽  
Automatic Feature Extraction ◽  
Band Limited

In this paper, the classification of normal controls (NC), very mild cognitive impairment and the early stage of Alzheimer’s disease (AD) known as mild cognitive impairment (MCI) from magnetic resonance imaging (MRI) is proposed, based on the two dimensional variational mode decomposition (2D-VMD) and deep convolutional neural network (DCNN). The 2D-VMD is applied to decompose the MRI scans into a discrete number of band limited intrinsic mode functions (BLIMFs). The automatic feature extraction, selection and optimization are performed using the proposed DCNN. The classification accuracy and learning speed of the 2D-VMD-DCNN method are compared with DCNN by taking the MRI data as input. The superior classification accuracy of the proposed 2D-VMD-DCNN method over DCNN method as well as other recently introduced prevalent methods is the major advantage for analyzing the biomedical images in the field of health care

scholarly journals Automatic Zebrafish Egg Phenotype Recognition from Bright-Field Microscopic Images Using Deep Convolutional Neural Network

2019 ◽  
Vol 9 (16) ◽  
pp. 3362 ◽  
Author(s):  
Shang Shang ◽  
Ling Long ◽  
Sijie Lin ◽  
Fengyu Cong
Keyword(s):  
Neural Network ◽  
Image Analysis ◽  
Convolutional Neural Network ◽  
Classification Accuracy ◽  
Deep Convolutional Neural Network ◽  
Microscopic Image ◽  
Bright Field ◽  
Microscopic Images ◽  
Phenotype Classification ◽  
Microscopic Image Analysis

Zebrafish eggs are widely used in biological experiments to study the environmental and genetic influence on embryo development. Due to the high throughput of microscopic imaging, automated analysis of zebrafish egg microscopic images is highly demanded. However, machine learning algorithms for zebrafish egg image analysis suffer from the problems of small imbalanced training dataset and subtle inter-class differences. In this study, we developed an automated zebrafish egg microscopic image analysis algorithm based on deep convolutional neural network (CNN). To tackle the problem of insufficient training data, the strategies of transfer learning and data augmentation were used. We also adopted the global averaged pooling technique to overcome the subtle phenotype differences between the fertilized and unfertilized eggs. Experimental results of a five-fold cross-validation test showed that the proposed method yielded a mean classification accuracy of 95.0% and a maximum accuracy of 98.8%. The network also demonstrated higher classification accuracy and better convergence performance than conventional CNN methods. This study extends the deep learning technique to zebrafish egg phenotype classification and paves the way for automatic bright-field microscopic image analysis.

Identification of Tomato Leaf Disease Detection using Pretrained Deep Convolutional Neural Network Models

2020 ◽  
Vol 21 (4) ◽  
pp. 625-635
Author(s):  
Anandhakrishnan T ◽  
Jaisakthi S.M Murugaiyan
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Early Stage ◽  
Computing Time ◽  
Network Models ◽  
Deep Convolutional Neural Network ◽  
Neural Network Models ◽  
Leaf Disease ◽  
Proposed Model ◽  
Deep Cnn

In this paper, we proposed a plant leaf disease identification model based on a Pretrained deep convolutional neural network (Deep CNN). The Deep CNN model is trained using an open dataset with 10 different classes of tomato leaves We observed that overall architectures which can increase the best performance of the model. The proposed model was trained using different training epochs, batch sizes and dropouts. The Xception has attained maximum accuracy compare with all other approaches. After an extensive simulation, the proposed model achieves classification accuracy better. This accuracy of the proposed work is greater than the accuracy of all other Pretrained approaches. The proposed model is also tested with respect to its consistency and reliability. The set of data used for this work was collected from the plant village dataset, including sick and healthy images. Models for detection of plant disease should predict the disease quickly and accurately in the early stage itself so that a proper precautionary measures can be applied to avoid further spread of the diseases. So, to reduce the main issue about the leaf diseases, we can analyze distinct kinds of deep neural network architectures in this research. From the outcomes, Xception has a constantly improving more to enhance the accuracy by increasing the number of epochs, without any indications of overfitting and decreasein quality. And Xception also generated a fine 99.45% precision in less computing time.

scholarly journals Transfer Learning for Predicting Conversion from Mild Cognitive Impairment to Dementia of Alzheimer’s Type based on 3D-Convolutional Neural Network

2019 ◽  
Author(s):  
Jinhyeong Bae ◽  
Jane Stocks ◽  
Ashley Heywood ◽  
Youngmoon Jung ◽  
Lisanne Jenkins ◽  
...  
Keyword(s):  
Neural Network ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Convolutional Neural Network ◽  
Transfer Learning ◽  
Brain Regions ◽  
Pharmacological Intervention ◽  
Dementia Of Alzheimer’S Type ◽  
3D Cnn

AbstractDementia of Alzheimer’s Type (DAT) is associated with a devastating and irreversible cognitive decline. As a pharmacological intervention has not yet been developed to reverse disease progression, preventive medicine will play a crucial role for patient care and treatment planning. However, predicting which patients will progress to DAT is difficult as patients with Mild Cognitive Impairment (MCI) could either convert to DAT (MCI-C) or not (MCI-NC). In this paper, we develop a deep learning model to address the heterogeneous nature of DAT development. Structural magnetic resonance imaging was utilized as a single biomarker, and a three-dimensional convolutional neural network (3D-CNN) was developed. The 3D-CNN was trained using transfer learning from the classification of Normal Control and DAT scans at the source task. This was applied to the target task of classifying MCI-C and MCI-NC scans. The model results in 82.4% classification accuracy, which outperforms current models in the field. Furthermore, by implementing an occlusion map approach, we visualize key brain regions that significantly contribute to the prediction of MCI-C and MCI-NC. Results show the hippocampus, amygdala, cerebellum, and pons regions as significant to prediction, which are consistent with current understanding of disease. Finally, the model’s prediction value is significantly correlated with rates of change in clinical assessment scores, indicating the model is able to predict an individual patient’s future cognitive decline. This information, in conjunction with the identified anatomical features, will aid in building a personalized therapeutic strategy for individuals with MCI. This model could also be useful for selection of participants for clinical trials.

scholarly journals Skin Lesion Classification With Deep Convolutional Neural Network: Process Development and Validation

10.2196/18438 ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. e18438
Author(s):  
Arnab Ray ◽  
Aman Gupta ◽  
Amutha Al
Keyword(s):  
Neural Network ◽  
Skin Cancer ◽  
Skin Lesion ◽  
Convolutional Neural Network ◽  
Process Development ◽  
Early Stage ◽  
Deep Convolutional Neural Network ◽  
Fine Tuning ◽  
Network Process ◽  
Lesion Classification

Background Skin cancer is the most common cancer and is often ignored by people at an early stage. There are 5.4 million new cases of skin cancer worldwide every year. Deaths due to skin cancer could be prevented by early detection of the mole. Objective We propose a skin lesion classification system that has the ability to detect such moles at an early stage and is able to easily differentiate between a cancerous and noncancerous mole. Using this system, we would be able to save time and resources for both patients and practitioners. Methods We created a deep convolutional neural network using an Inceptionv3 and DenseNet-201 pretrained model. Results We found that using the concepts of fine-tuning and the ensemble learning model yielded superior results. Furthermore, fine-tuning the whole model helped models converge faster compared to fine-tuning only the top layers, giving better accuracy overall. Conclusions Based on our research, we conclude that deep learning algorithms are highly suitable for classifying skin cancer images.

scholarly journals Diagnosis of Alzheimer’s Disease with Ensemble Learning Classifier and 3D Convolutional Neural Network

Sensors ◽  
2021 ◽  
Vol 21 (22) ◽  
pp. 7634
Author(s):  
Peng Zhang ◽  
Shukuan Lin ◽  
Jianzhong Qiao ◽  
Yue Tu
Keyword(s):  
Neural Network ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Convolutional Neural Network ◽  
Ensemble Learning ◽  
Memory Loss ◽  
Main Tool ◽  
Disease Diagnosis

Alzheimer’s disease (AD), the most common type of dementia, is a progressive disease beginning with mild memory loss, possibly leading to loss of the ability to carry on a conversation and respond to environments. It can seriously affect a person’s ability to carry out daily activities. Therefore, early diagnosis of AD is conducive to better treatment and avoiding further deterioration of the disease. Magnetic resonance imaging (MRI) has become the main tool for humans to study brain tissues. It can clearly reflect the internal structure of a brain and plays an important role in the diagnosis of Alzheimer’s disease. MRI data is widely used for disease diagnosis. In this paper, based on MRI data, a method combining a 3D convolutional neural network and ensemble learning is proposed to improve the diagnosis accuracy. Then, a data denoising module is proposed to reduce boundary noise. The experimental results on ADNI dataset demonstrate that the model proposed in this paper improves the training speed of the neural network and achieves 95.2% accuracy in AD vs. NC (normal control) task and 77.8% accuracy in sMCI (stable mild cognitive impairment) vs. pMCI (progressive mild cognitive impairment) task in the diagnosis of Alzheimer’s disease.

scholarly journals Classification of plant seedlings using deep convolutional neural network architectures

2022 ◽  
Vol 2161 (1) ◽  
pp. 012006
Author(s):  
Namratha Makanapura ◽  
C Sujatha ◽  
Prakash R Patil ◽  
Padmashree Desai
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Weed Management ◽  
Early Stage ◽  
Vital Role ◽  
Deep Convolutional Neural Network ◽  
Network Architectures ◽  
Weed Species ◽  
Neural Network Architectures ◽  
Plant Seedlings

Abstract Weed management has a vital role in applications of agriculture domain. One of the key tasks is to identify the weeds after few days of plant germination which helps the farmers to perform early-stage weed management to reduce the contrary impacts on crop growth. Thus, we aim to classify the seedlings of crop and weed species. In this work, we propose a plant seedlings classification using the benchmark plant seedlings dataset. The dataset contains the images of 12 different species where three belongs to plant species and the other nine belongs to weed species. We implement the classification framework using three different deep convolutional neural network architectures, namely ResNet50V2, MobileNetV2 and EfficientNetB0. We train the models using transfer learning and compare the performance of each model on a test dataset of 833 images. We compare the three models and demonstrate that the EfficientNetB0 performs better with an average F1-Score of 96.26% and an accuracy of 96.52%.

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