scholarly journals Non Invasive Measurement of Hemoglobin using Optical Sensor

2019 ◽  
Vol 8 (2S11) ◽  
pp. 4068-4070 ◽  

Hemoglobin (hb) concentration is a basic parameter in the human blood, the absense of which causes anemia. The proposed work stays away from the superfluous wastage of blood while estimating hb concentration which could have serious impact on a anemic patient. There are fundamentally two classifications to be specific, invasive and non-invasive methods.In the invasive method blood sample is collected by hurtful needle stick. After that the collected blood sample is sent to a laboratory for examination. Then the results are announced back to the docter later which possibly leads to analysis and treatement delay. A non-invasive technique permits torment free online patient checking framework with least danger of infection. An optical non-invasive system is introduced for Hb focus. In this anew advanced system, retention of light by oxygenated and deoxygenated hemoglobin is estimated at two wavelengths 660nm and 940nm. The specific wavelength of light is acquired from red and IR LED. The absorption coefficient of blood differs at various wavelength this reality is utilized to compute concentration of the hemoglobin.

Sensors ◽  
2021 ◽  
Vol 21 (6) ◽  
pp. 2162
Author(s):  
Mohammad Mamouei ◽  
Subhasri Chatterjee ◽  
Meysam Razban ◽  
Meha Qassem ◽  
Panayiotis A. Kyriacou

Dermal water content is an important biophysical parameter in preserving skin integrity and preventing skin damage. Traditional electrical-based and open-chamber evaporimeters have several well-known limitations. In particular, such devices are costly, sizeable, and only provide arbitrary outputs. They also do not permit continuous and non-invasive monitoring of dermal water content, which can be beneficial for various consumer, clinical, and cosmetic purposes. We report here on the design and development of a digital multi-wavelength optical sensor that performs continuous and non-invasive measurement of dermal water content. In silico investigation on porcine skin was carried out using the Monte Carlo modeling strategy to evaluate the feasibility and characterize the sensor. Subsequently, an in vitro experiment was carried out to evaluate the performance of the sensor and benchmark its accuracy against a high-end, broad band spectrophotometer. Reference measurements were made against gravimetric analysis. The results demonstrate that the developed sensor can deliver accurate, continuous, and non-invasive measurement of skin hydration through measurement of dermal water content. Remarkably, the novel design of the sensor exceeded the performance of the high-end spectrophotometer due to the important denoising effects of temporal averaging. The authors believe, in addition to wellbeing and skin health monitoring, the designed sensor can particularly facilitate disease management in patients presenting diabetes mellitus, hypothyroidism, malnutrition, and atopic dermatitis.


2017 ◽  
Vol 38 (5) ◽  
pp. 780-792 ◽  
Author(s):  
Nobuyuki Kudomi ◽  
Yukito Maeda ◽  
Hiroyuki Yamamoto ◽  
Yuka Yamamoto ◽  
Tetsuhiro Hatakeyama ◽  
...  

CBF, OEF, and CMRO2 images can be quantitatively assessed using PET. Their image calculation requires arterial input functions, which require invasive procedure. The aim of the present study was to develop a non-invasive approach with image-derived input functions (IDIFs) using an image from an ultra-rapid O2 and C15O2 protocol. Our technique consists of using a formula to express the input using tissue curve with rate constants. For multiple tissue curves, the rate constants were estimated so as to minimize the differences of the inputs using the multiple tissue curves. The estimated rates were used to express the inputs and the mean of the estimated inputs was used as an IDIF. The method was tested in human subjects ( n = 24). The estimated IDIFs were well-reproduced against the measured ones. The difference in the calculated CBF, OEF, and CMRO2 values by the two methods was small (<10%) against the invasive method, and the values showed tight correlations ( r = 0.97). The simulation showed errors associated with the assumed parameters were less than ∼10%. Our results demonstrate that IDIFs can be reconstructed from tissue curves, suggesting the possibility of using a non-invasive technique to assess CBF, OEF, and CMRO2.


2019 ◽  
Vol 6 (2) ◽  
pp. 349 ◽  
Author(s):  
Rajendra Kumar ◽  
Nithin . ◽  
Sudha Rudrappa

Background: The aim of this study is to determine the success rate and safety of a non-invasive technique to obtain clean-catch midstream urine samples in newborns.Methods: Prospective bedside clinical study. After obtaining written informed consent,120 consecutive newborns admitted in NICU with no dehydration, poor feeding, need for immediate urine sample by invasive method  for whom urine collection was advised for various reasons who met the inclusion criteria were included in the study with consent being taken from the parents. After adequate milk intake supra pubic and lumbar para vertebral areas were stimulated in repeated cycles of 30 s until micturition began.Results: Success rate in obtaining a midstream urine sample within 5 min. The success rate was 90%. The mean time taken to collect urine was 64.24s, for males it was 62.55s and for females 65.93s.Conclusions: The technique has been demonstrated to be safe, quick and effective. The discomfort and time consumption usually associated with bag collection methods as well as invasive techniques can be avoided.


2016 ◽  
Vol 70 (3) ◽  
pp. 153-157
Author(s):  
Elena Dzikova ◽  
Goran Dimitrov ◽  
Olivera Stojceva-Taneva

Abstract Aims. The prenatal prediction of fetal maturity is very important, since neonatal respiratory distress syndrome (RDS) is one of the biggest causes of neonatal mortality. Our aim was to investigate a new non-invasive method for prediction of fetal maturity and to determine in which group according to gestational age of the fetus, the treatment works the best and in which cases it is necessary to be repeated. Methods. We examined 60 patients (30 with impending preterm delivery, divided in 3 groups: 28-30, 30-32, and 32-34 gestational weeks and 30 controls), at the University Clinic for Gynecology and Obstetrics, Medical Faculty, University “Ss. Cyril and Methodius”, Skopje, R. Macedonia. Fetal maturity was examined using ultrasound histogram from fetal lungs and liver, correlated with gestational age and postpartum RDS. Where possible, we performed amniocentesis for lamellar body count (LBC) to correlate our results with the current invasive method for prediction of fetal maturity. Results. Pre-therapy investigation showed a strong fetal immaturity in 28-32 weeks of gestation and less evident fetal immaturity in 32-34 weeks of gestation. Seventy-two hours post-treatment, fetal maturation was low in the first group, higher in the second and the highest in the third group. Amniocentesis for LBC showed correlation with the ultrasound results. Postpartum results were correlated with pre-delivery ultrasound and showed significance of p <0.05. Conclusion. The results obtained in our study were with high significance, and they were in correlation with other similar studies. However, more extensive investigations should be made to replace the current invasive technique.


IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 84178-84179
Author(s):  
MD. Rezwanul Haque ◽  
S. M. Taslim Uddin Raju ◽  
MD. Asaf-Uddowla Golap ◽  
M. M. A. Hashem

2007 ◽  
Vol 30 (3) ◽  
pp. 36
Author(s):  
Sara Croteau ◽  
Caroline Vallière ◽  
Julie Martin ◽  
Jean Bussières ◽  
Jean-Roch Boudreault ◽  
...  

Background: Obesity is associated with high blood pressure. Measurement of blood pressure (BP) in morbid obesity with a larger cuff bladder may be erroneous due to the anatomy of their upper limb and/or a nonsuitable cuff bladder. The objective of the study was to compare a non-invasive technique of BP measurement on the forearm with an appropriate standard blood cuff bladder to an invasive method (intra-arterial measurement in the radial artery) in two groups of subjects; non obese (NO) and morbidly obese (MO). Methods: Twenty-seven NO subjects with a mean body mass index (BMI) of 25,6 ± 2,7 kg/m2 were evaluated using two different techniques for blood pressure measurement. Measures were performed, in a supine position, at the forearm level with a standard cuff bladder (Welch Allyn, NY, USA) and on the opposite forearm using an intra-arterial access. The NO group was compared to 20 MO subjects with a mean BMI of 5,1 ± 8,7 kg/m2. The MO group was evaluated during a bariatric surgery procedure, with regular intervals (10 to 15 min) using the same two methods described above. Results: A difference was observed between the two techniques of blood pressure measurements (P < 0.05 and P < 0.01 intra-arterial vs. cuff bladder for the NO and the MO groups respectively) (see Table). Correlations between the two techniques were observed in the NO group (P < 0.001) for the systolic BP (r=0,823) and the diastolic BP (r=0,769). Similar correlations were also observed in the MO group for the systolic BP (r=0,792, P < 0,001) and the diastolic BP (r=0,830, P < 0,001; Table). *** Table in Full Text PDF. *** Conclusion: Although different, BP measurements at the forearm level in MO subjects seems to be clinically valid. This technique may be used in this specific population as an alternative for the measurement of BP.


Author(s):  
P. P. Loshytskyi ◽  
D. Yu. Mynzyak

<p class="1">Non-invasive method of determining human blood sugar is explained by measuring stochastic characteristics of the water. Measurements of blood glucose of patients by the proposed method is shown by results obtained with an accuracy of ±0,3 mmol/l coincide with the results obtained by a conventional method using a glucometer.</p>


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