Through a survey in Kakatpur block, Odisha, twenty-one numbers of anestrous cattle were selected and equally divided in to three groups (T0, T1 and T2, n=7) for the experiment. T0 was kept as control (farmer’s practice), while T1 and T2 were provided with area specific mineral mixture (Ca, P, Mn, Cu, Zn) at 50g/day/animal and bypass fat at 100 g/day/animal, respectively for 60days. Average daily gain was significantly higher in T1 and T2 as compared to that of T0. Significant improvement in blood glucose, cholesterol, triglyceride and SGPT status was observed after various treatments. Due to mineral supplementation, all blood mineral status was improved. T1 and T2 groups exhibited better ovarian status and conception rate after treatment. Although, highest conception rate was observed in T2 group. Therefore, it can be concluded that supplementation of mineral mixture and bypass fat improved reproductive efficiency of anestrous animals along higher daily gain.