ANALYSIS AND CORELATION OF A PANEL OF SERUM BIOMARKERS WITH TREATMENT OUTCOME OF ISCHEMIC HEART DISEASE IN A TERTIARY CARE HOSPITAL OF WEST BENGAL

2021 ◽  
pp. 56-60
Author(s):  
Sudeshna Baral ◽  
Srabani Biswas ◽  
Sharmistha Choudhuri ◽  
Biswajit Majumdar
Keyword(s):  
Heart Disease ◽  
Treatment Outcome ◽  
Ischemic Heart Disease ◽  
Homocysteine Level ◽  
Strong Association ◽  
Tertiary Care ◽  
Serum Lipoprotein ◽  
Ischemic Heart ◽  
Care Hospital ◽  
Diagnostic Potential

Background :In India Ischemic heart disease (IHD ) is the of most common causes of mortality and morbidity . Several studies have pointed out a strong association of serum Lipoprotein (a) , Homocysteine and highly sensitive – C reactive protein [hs-CRP],with IHD , but these markers have been studied in isolation . Aim: The aim of the study was to assess diagnostic potential of the above biomarkers as well as their ability to reect treatment outcome. Results : The results of statistical analysis showed that levels of serum Lp (a) and serum homocysteine were signicantly raised in patients in of IHD compared to their apparently age and sex matched controls whereas the level of serum hsCRP level did not showed any signicant difference in between cases and controls. We also found signicant lower value of serum level Lp (a), homocysteine and hsCRP in 3 months and 6 months post treated cases compared to untreated cases of IHD. But failed to show any signicant correlation in between serum levels of Lp(a) , hsCRP and Homocysteine level with disease severity( LVEF%) of IHD. Conclusion :So the serum Lp(a) , hsCRP and Homocysteine level is associated with increase risk factor of IHD and would be a better upcoming diagnostic and marker for diagnosis of IHD patients .

scholarly journals Coronary angiographic profile of patients of ischemic heart disease admitted in a tertiary care hospital

2015 ◽  
Vol 67 ◽  
pp. S37
Author(s):  
Rammohan Roy ◽  
Hema Malathi ◽  
Imran Ahmed ◽  
Bhabani Prasad Chatterjee ◽  
Santanu Guha
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
Care Hospital

scholarly journals An audit of indoor morbidity and mortality in a medical ward at a Tertiary Care Hospital

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Abeer Qadir ◽  
Muhammad Arif Nadeem ◽  
Atif Munir ◽  
Zafar Ullah Khan
Keyword(s):  
Heart Disease ◽  
Liver Disease ◽  
Ischemic Heart Disease ◽  
Chronic Liver Disease ◽  
Tertiary Care ◽  
Chronic Liver ◽  
Ischemic Heart ◽  
Care Hospital ◽  
Cerebrovascular Accidents ◽  
Number Of Patients

There is a great geographical variation in disease burden around the world, which is due primarily to environmental, genetic, social and economic factors. Similar variations exist in worldwide mortality figures from a particular disease that can be attributed almost entirely to the access and efficacy of healthcare facilities. We did this audit to identify the major causes of morbidity and mortality in patients admitted in a medical unit of a tertiary care hospital and to highlight the importance of primary prevention. The audit was carried out in West Medical Ward Mayo Hospital Lahore, Pakistan from 1st January 2004 to 31st December 2004. All patients admitted with medical problems from the Outpatient and Emergency Departments were included. During the year 2004, a total of 2045 patients were admitted, out of which maximum number of patients admitted in the ward were suffering from chronic liver disease (17%) followed by ischemic heart disease (14.4%) cerebrovascular accidents (10.4%) and renal diseases. Total number of deaths were 321 with male mortality was 167 (14.40%) and female mortality 154 (17.40%). Chronic liver disease also had the highest mortality (16.8%) followed by cerebrovascular accidents (14%), renal disease (11.5%) and ischemic heart disease (7.8%). Even the mortality due to chronic liver disease was significantly higher (p <0.01) than ischernic heart disease. The number of patients having the four common diseases having age 45 years or more (770) was significantly greater (p <0.0001) then the number of patients (279) in the age range of 15 to 44 years. It was observed that significantly greater number of male patients (595) had morbidity than females (462), (p <0.0001), while mortality has no difference. Chronic liver disease, ischemic heart disease and cerebrovascular accidents are the diseases putting maximum burden on our health resources and disabling our productive population. This audit highlights the fact that all these three groups of diseases can be prevented and thus obviates the need of primary prevention of these major killers.

Psychosocial and Behavioral Risk Factors of Early Onset of Ischemic Heart Disease among the Patients Presenting at a Tertiary Care Hospital

2021 ◽  
Vol 12 (09) ◽  
pp. 703-705
Author(s):  
Shaheen Nazakat ◽  
Dr Muhammad Sajid
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Early Onset ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
Behavioral Risk ◽  
Care Hospital ◽  
Control Research ◽  
Lahore City

This study investigate the psychological, behavioral, anthropometric, and social factors that may cause a possible early onset of Ischemic Heart Disease (IHD) at a tertiary care hospital. Case-control research design was used in the present study. The present study was conducted in a tertiary care hospital in Lahore city, Punjab, Pakistan. Patients in the cardiology ward of a tertiary care hospital in Lahore City aged between 35-55 years were included in the study.

scholarly journals Association of Diabetes and Hypertension as risk factors with Ischemic Heart Disease among patients visiting a Public Sector Tertiary Care Hospital of Karachi, Pakistan

2021 ◽  
Vol 10 (4) ◽  
pp. 215-219
Author(s):  
Zulfiqar Ali Shaikh ◽  
Javeria Shamim ◽  
Akmal Khurshid Bhatti ◽  
Sahar Soomro ◽  
Zareen Kiran ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Family History ◽  
Public Sector ◽  
Ischemic Heart Disease ◽  
Sedentary Lifestyle ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
P Value ◽  
Care Hospital

Background: Ischemic Heart Disease (IHD) is a leading cause of morbidity and mortality worldwide. IHD results from myocardial ischemia, and occurs whenever perfusion outgrows the demand. Though lethal, but can be prevented by modification of predisposing conditions, most important are diabetes and hypertension. Almost fifty percent of IHD patients are found hypertensive with or without being diabetic. The objective of the study was to determine association of diabetes and hypertension as risk factors for IHD patients Methods: This was a hospital-based cross-sectional study that included 199 IHD patients of 35-70 years age, visiting Civil Hospital Karachi, a tertiary care public sector hospital, from September 2017 to January 2018 by using non-probability convenient sampling technique. The patients were approached in the hospital and briefed about the purpose of the study. A pre-tested, structured close ended questionnaire was used to collect the data. Data entry and analysis were done by using SPSS version 20.0. A p-value of <0.05 was considered as statistically significant. Results: Out of 199 participants, 156 (78%) were males while 43 (22%) were females; 119 60%) were 56-65 years of age. Family history of ischemic heart diseases was unremarkable in 126 (63%) patients. In total, 122 (61%) were diabetic; among them, 24 were of less than 40years and 98 of more than 40years of age. The older age of the diabetics had a direct association with the risk of IHD (p-value <0.05). About 83% had a non-significant family history for diabetes; and 83% of the total study participants were having a sedentary lifestyle. Out of 199, 166 (83%) had never checked their blood pressures earlier. The lifestyle, diet, addiction, and duration of hypertension had a strong association with IHD (p-value <0.05). Conclusion: IHD occurs more frequently in males of 56-65 years age, with insignificant family history for IHD and diabetes. The IHD is associated with hypertension and diabetes along with sedentary lifestyle, unhealthy diet and smoking/tobacco addiction.

scholarly journals DIABETICS IN A LOW SOCIOECONOMIC COHORT;

2017 ◽  
Vol 24 (03) ◽  
pp. 403-408
Author(s):  
Ayesha Nageen ◽  
Saera Suhail Kidwai ◽  
Farhat BashIr ◽  
Jamal Ara ◽  
Syed Muhammad Munir
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Ischemic Heart Disease ◽  
Strong Association ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
Socioeconomic Group ◽  
Cross Sectional ◽  
Low Socioeconomic

Objectives: To study the latest trend of cardiometabolic risk factors in diabeticsin a low socioeconomic group. Design: Cross sectional observational. Place and duration:Three tertiary care hospitals of Karachi. June 2013 – Dec 2014. Methods: 824 type II adultdiabetic patients of both genders were included. History was taken regarding diabetes, ischemicheart disease, hypertension, and cerebrovascular accidents. Blood pressure and BMI wasrecorded. Investigations were done for dyslipidemia. SPSS 16 was used for means, frequenciesand proportions. Results: There were 276 males (33%) and 548 females (67%) with a meanage of 52 years (±9.67). Mean duration of diabetes was 9.36 years (± 6.39). Hypertension waspresent in 375 (45%) diabetics of which males were 124(33%) and females were 251(66.6%).Frequency of hypertension in total diabetic males is 45% (125) and in females 45.6 %( 140).Ischemic heart disease was present in 105 patients (12.7%) in which males were 45(42.8%) andfemales were 60(57.1%). The male percentage of ischemic heart disease was 16.3% (45) of thetotal males and females 11 %( 40). Stroke was found in 19 patients (2.3%) equally distributed inboth genders. Mean Body mass Index was 28.02 (+/- 5.31) with 135 (16.3%) being overweightand 529 (64.2%) obese. Dyslipidemia was present in 250 (42.3%) out of 591 patients. Smokinghistory taken in 614 patients showed that 73 (11.8%) were smokers and/or chewed tobacco.Out of a total of 595 patients, 372 (62.5%) patients had metabolic syndrome. Conclusion:There is a strong association and high prevalence of cardiovascular risk factors in diabetics ina low socioeconomic group. Factors such as hypertension, dyslipidemia, obesity, and smokingfurther multiply the cardiovascular risk ratio in diabetics.

scholarly journals Epidemiological study of ischemic heart disease in patients admitted in intensive care unit in the tertiary care hospital

2017 ◽  
Vol 4 (6) ◽  
pp. 1892
Author(s):  
Poonam Vijay Sancheti ◽  
Suresh Konappa Mangulikar
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Care Hospital ◽  
Epidemiological Factors

Background: The aim of the study was to assess the epidemiological factors of ischemic heart disease in patients admitted in intensive care unit in the tertiary care hospital. Socio demographic profile of ischemic heart disease patients along with behavioral risk factors, stress factors, dietary habits and associated comorbidities were studied.Methods: Present study was carried out in patients of IHD admitted in ICU of tertiary care hospital. History about epidemiological factors was obtained from patients or relatives by separate proformas.Results: Occurrence of disease had decreasing trend with the increase in literacy status of patients, which was statistically significant at p <0.0001. Maximum patients in the study were from socioeconomic class V i.e. 144 (36.64%). Study showed that household stress was more commonly associated with occurrence of disease which was significant statistically at p <0.001. Most common behavioral risk factor seen in patients was smokeless tobacco consumption. The occurrence of ischemic heart disease was seen more in the group of patients consuming mixed diet and consuming palm oil. Most common comorbidity in patients admitted for ischemic heart disease was hypertension, which was statistically significant at p <0.001.Conclusions: Age, literacy, socioeconomic status of the patient, history of behavioral risk factors in the patient, stress and comorbidities are related to the occurrence of ischemic heart disease. 

scholarly journals Study of clinical profile of ischemic heart disease patients admitted in tertiary care hospital

2017 ◽  
Vol 4 (9) ◽  
pp. 3191 ◽  
Author(s):  
Poonam Vijay Sancheti ◽  
Suresh Konappa Mangulikar
Keyword(s):  
Heart Disease ◽  
Chest Pain ◽  
Ischemic Heart Disease ◽  
Cardiac Failure ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Ischemic Heart ◽  
Care Hospital ◽  
Tertiary Care Centre

Background: Cardiovascular diseases have assumed epidemic proportions in India. The study was undertaken to know the clinical presentation of ischemic heart disease. It also included time lapsed between symptoms and admission which is important outcome indicator. The aim and objective was to study the clinical profile of ischemic heart disease patients admitted in tertiary care hospital.Methods: The study was done in IHD patients admitted in ICU of tertiary care hospital. The study period was June 2014 to June 2015. Detailed clinical data like symptoms, signs, associated illnesses, general and systemic examination was included. Results: 33.59% patients were brought to tertiary care centre within 3-6 hours of onset of symptoms. Out of total, 63.61% presented with chest pain not relieved in ten minutes followed by 21.89% patients who had chest pain which relieved in ten minutes. 68.95% patients had associated sweating, 35.62% had associated breathless-ness and 16.03% had associated swelling over feet. Associated symptoms with chest pain were not exclusive of each other. 62.85% patients were of STEMI, 21.37% patients were classified as NSTMI and 15.78% were patients of unstable angina. Cardiac failure was seen in 69.52% patients. Conclusions: Most of the patients were of STEMI with most common complain of chest pain and most common clinical complication was cardiac failure in the patients. 

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