scholarly journals STUDY OF PREVALENCE OF NEPHROPATHY IN NEWLY DIAGNOSED TYPE 2 DIABETES MELLITUS PATIENTS

2020 ◽  
pp. 1-2
Author(s):  
Abhijeet Kuma ◽  
Pankaj Hans ◽  
Ram Raj Ravi

INTRODUCTION: Diabetes Mellitus is one of the commonest diseases of the world.The dangerous fact about diabetes is that it is ''Silent Killer''.By the time patient is diagnosed to have diabetes,he/she is already affected with complications like diabetic nephropathy, retinopathy and neuropathy. It is specially worse in India, where various factors delay the diagnosis of diabetes compared to developed nations. Diabetic nephropathy and microalbuminuria are also strong predictors of cardiovascular and overall mortality in patients of diabetes,and hence are vital indicators in the patients. AIM: To find out prevalence of nephropathy in newly diagnosed Type 2 diabetes mellitus patients and other complications. METHODS:.In this cross-sectional study first 100 pts from PMCH Medicine OPD and IPD of age>20yrs of type2 diabetes mellitus during study period were taken and evaluated for HbA1c, urea, creatinine, Microalbuminuria, LVH, & blood sugar levels. RESULT: .It was found that 34 % of patients of type 2 diabetes mellitus have developed nephropathy at the time of detection.Among these 34 patients 18 have developed LVH and 13 out of 66 diabetic patients developed LVH.Result is significant with p<0.001.92% of newly diagnosed diabetic patients have HbA1c>7.5% (p=0.01 significant) CONCLUSION:. diabetic nephropathy is much larger than imagined in freshly diagnosed/new onset cases of DM type 2,especially compared to more developed nations.Microalbuminuria in patients with diabetes is a potential risk factor not only for kidney function impairment but also a marker for high risk of cardiovascular complications.

2017 ◽  
Vol 70 (2) ◽  
pp. 265-270 ◽  
Author(s):  
José Cláudio Garcia Lira Neto ◽  
Mayra de Almeida Xavier ◽  
José Wicto Pereira Borges ◽  
Márcio Flávio Moura de Araújo ◽  
Marta Maria Coelho Damasceno ◽  
...  

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.


Author(s):  
SARASWATI PRADIPTA ◽  
HERI WIBOWO ◽  
DANTE SAKSONO HARBUWONO ◽  
EKOWATI RAHAJENG ◽  
RAHMA AYU LARASATI ◽  
...  

Objective: Type 2 diabetes mellitus (T2DM) patients tend to have abnormal lipid profiles, explaining the association between elevated cholesterol andtriglyceride levels in diabetic patients and coronary heart disease. This study aims to evaluate how the common risk factors for dyslipidemia affectthe lipid profile of diabetic patients and to determine which factors can be used as predictors for the occurrence of dyslipidemia in T2DM patients.Methods: A total of 238 diabetic patients (63 male and 175 female; age: 31–70 years) were enrolled in this cross-sectional study. All of them hadundergone regular examinations in cohort studies on risk factors for non-communicable diseases conducted by the Ministry of Health in Bogorbetween December 2017 and January 2018.Results: The result found that age differences did not affect lipid profile levels, and the females had higher mean values of body mass index (p<0.001),total cholesterol (TC) (p<0.05), and high-density lipoprotein (HDL) (p<0.001) than the males. The most common occurrences of dyslipidemia werehigh TC level (57.1%), followed by high low-density lipoprotein (LDL) level (47.1%), high triglyceride level (37.4%), and low HDL level (16.4%). Beingoverweight was found to be the best predictor of dyslipidemia.Conclusion: The results of this study suggest that in T2DM patients, sex affects TC and HDL levels, whereas age does not exert a significant effect onthe lipid profiles. In addition, poor glycemic control, hypertension, and obesity may serve as predictors of dyslipidemia in T2DM patients.


2021 ◽  
Vol 10 (1) ◽  
pp. 29-32
Author(s):  
Sanjay Shrestha ◽  
Rajesh Kumar Mandal ◽  
Kijan Maharjan

Background and Aims: Microalbuminuria is an early marker of diabetic nephropathy, which accounts for a significant reduction in life expectancy of diabetic patients. Timely detection of microalbuminuria facilitates appropriate preventive and therapeutic approaches to minimize risks. The aim of this study is to determine the prevalence and association of microalbuminuria with clinical profile and complications of type 2 diabetes mellitus. Methods: This study was a descriptive, cross sectional study involving 100 diabetic subjects between July 2018 to January 2019 at Bir Hospital. Microalbuminuria (mg/dl) was defined as spot urine albumin to creatinine ratio of 30-300 mg/g (Kidney Disease Improving Global Outcomes guidelines) in a single spot urine sample. Statistical analysis was done using Statistical package for the social sciences version 20. Results: Microalbuminuria was found in 35% of the sample and the rate was significantly higher among males (P =0.027). Microalbuminuria was significantly related to Body mass index (P = 0.018), duration of diabetes (P =0.000), retinopathy (P = 0.000) and stroke (P = 0.043). No statistically significant relation was found between microalbuminuria and age (P = 0.366), hypertension (P = 0.208), HbA1c (P = 0.098), dyslipidemia (P = 0.171) and ischemic heart disease (P = 0.651). Conclusions: This study shows high prevalence of microalbuminuria in Nepalese Type 2 diabetes mellitus. Screening for microalbuminuria should be done for all the type 2 diabetes mellitus patients for early detection and management of complications of diabetes mellitus.  


2020 ◽  
Vol 7 (3) ◽  
pp. 497
Author(s):  
Aishhwarrya Umeshchandara G. ◽  
Ravi K.

Background: Anemia is more frequent and severe in diabetics compared to non-diabetic patients. Chronic anemia results in tissue hypoxia, which is known to play a key role in diabetes-associated organ damage. Hence it is important to diagnose and correct anemia in diabetic patients. This study was done to elucidate the effect of glycemic control on haemoglobin levels in patients with type 2 Diabetes mellitus.Methods: The present study is an observational, cross sectional study conducted between November 2017 to May 2019 carried out in hospitals attached to Bangalore Medical college and Research Institute. A sample of 60 patients with Diabetes mellitus were included, out of which 28 were female and 32 were male patients.Results: Study was conducted on 60 patients, the age distribution was between 29yrs to 88yrs with mean age was 56±11yrs. Out of 60 patients 23 patients had anemia. There was slight positive correlation between haemoglobin percentage and HbA1c. But this was not statistically significant.Conclusions: The study concludes that Glycemic control was not found to influence the Haemoglobin levels in patients with Type 2 diabetes mellitus in a significant manner. In subjects with anemia, multiple other issues need to be addressed for improvement in haematocrit value and prevention of complications of diabetes apart from glycemic control.


2015 ◽  
Vol 10 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Fayeza Karim ◽  
Qazi Shamima Akter ◽  
Shamima Jahan ◽  
Afruza Khanom ◽  
Samira Haque ◽  
...  

Background: Complication of diabetes mellitus (DM) includes coagulation impairment. Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular disease (CVD).Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in type 2 diabetes mellitus for observing their coagubility status.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred age, BMI matched healthy subjects were included as control in this study. Patients were selected from BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated by auto analyzer. For statistical analysis unpaired student’t test was used.Results: In this study PT and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation impairment.Bangladesh Soc Physiol. 2015, June; 10(1): 26-29


2020 ◽  
Vol 11 (4) ◽  
pp. 7271-7274
Author(s):  
Krithik Jain N ◽  
XavierJayseelan C

The aim of the study is to find the incidence of refractive errors in diabetic individuals. Diabetes mellitus is highly prevalent in the current world in both developing and developed countries due to the lifestyle modifications. Refractive errors of eye are a very common group of disorder associated with diabetic people leading to the impairment of vision. Hence the study of incidence of refractive errors in patients with type 2 Diabetes mellitus was conducted. It was a cross-sectional study conducted at a tertiary health care centre and following was the methodology. One hundred eyes of fifty individuals were taken into consideration from Jan 2020 to March 2020, who were affected with type 2 Diabetes mellitus. These fifty individuals underwent subjective refraction of both the eyes. The results obtained were only 17 eyes (17%) being emmetropic, remaining 83 eyes (83%) were found to be ametropic. In the 83 ametropic eyes 22 eyes (22%) were myopic, 39 eyes (39%) were hypermetropic and 22 eyes (22%) had astigmatism. In the current Cross-sectional study refractive errors were noted in 83% of individual and hypermetropia being the most common error with a prevalence of 39%.


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