scholarly journals Prevalence of Metabolic Syndrome in individuals with Type 2 Diabetes Mellitus

2017 ◽  
Vol 70 (2) ◽  
pp. 265-270 ◽  
Author(s):  
José Cláudio Garcia Lira Neto ◽  
Mayra de Almeida Xavier ◽  
José Wicto Pereira Borges ◽  
Márcio Flávio Moura de Araújo ◽  
Marta Maria Coelho Damasceno ◽  
...  

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.

Author(s):  
SARASWATI PRADIPTA ◽  
HERI WIBOWO ◽  
DANTE SAKSONO HARBUWONO ◽  
EKOWATI RAHAJENG ◽  
RAHMA AYU LARASATI ◽  
...  

Objective: Type 2 diabetes mellitus (T2DM) patients tend to have abnormal lipid profiles, explaining the association between elevated cholesterol andtriglyceride levels in diabetic patients and coronary heart disease. This study aims to evaluate how the common risk factors for dyslipidemia affectthe lipid profile of diabetic patients and to determine which factors can be used as predictors for the occurrence of dyslipidemia in T2DM patients.Methods: A total of 238 diabetic patients (63 male and 175 female; age: 31–70 years) were enrolled in this cross-sectional study. All of them hadundergone regular examinations in cohort studies on risk factors for non-communicable diseases conducted by the Ministry of Health in Bogorbetween December 2017 and January 2018.Results: The result found that age differences did not affect lipid profile levels, and the females had higher mean values of body mass index (p<0.001),total cholesterol (TC) (p<0.05), and high-density lipoprotein (HDL) (p<0.001) than the males. The most common occurrences of dyslipidemia werehigh TC level (57.1%), followed by high low-density lipoprotein (LDL) level (47.1%), high triglyceride level (37.4%), and low HDL level (16.4%). Beingoverweight was found to be the best predictor of dyslipidemia.Conclusion: The results of this study suggest that in T2DM patients, sex affects TC and HDL levels, whereas age does not exert a significant effect onthe lipid profiles. In addition, poor glycemic control, hypertension, and obesity may serve as predictors of dyslipidemia in T2DM patients.


2021 ◽  
Vol 10 (1) ◽  
pp. 29-32
Author(s):  
Sanjay Shrestha ◽  
Rajesh Kumar Mandal ◽  
Kijan Maharjan

Background and Aims: Microalbuminuria is an early marker of diabetic nephropathy, which accounts for a significant reduction in life expectancy of diabetic patients. Timely detection of microalbuminuria facilitates appropriate preventive and therapeutic approaches to minimize risks. The aim of this study is to determine the prevalence and association of microalbuminuria with clinical profile and complications of type 2 diabetes mellitus. Methods: This study was a descriptive, cross sectional study involving 100 diabetic subjects between July 2018 to January 2019 at Bir Hospital. Microalbuminuria (mg/dl) was defined as spot urine albumin to creatinine ratio of 30-300 mg/g (Kidney Disease Improving Global Outcomes guidelines) in a single spot urine sample. Statistical analysis was done using Statistical package for the social sciences version 20. Results: Microalbuminuria was found in 35% of the sample and the rate was significantly higher among males (P =0.027). Microalbuminuria was significantly related to Body mass index (P = 0.018), duration of diabetes (P =0.000), retinopathy (P = 0.000) and stroke (P = 0.043). No statistically significant relation was found between microalbuminuria and age (P = 0.366), hypertension (P = 0.208), HbA1c (P = 0.098), dyslipidemia (P = 0.171) and ischemic heart disease (P = 0.651). Conclusions: This study shows high prevalence of microalbuminuria in Nepalese Type 2 diabetes mellitus. Screening for microalbuminuria should be done for all the type 2 diabetes mellitus patients for early detection and management of complications of diabetes mellitus.  


2019 ◽  
Vol 9 (2) ◽  
pp. 24-29
Author(s):  
Santosh Timalsina ◽  
Pratima Pandit

Introduction: The metabolic syndrome (MetS) is a cluster of risk fac­tors that is responsible for most of the excess cardiovascular morbidity amongst patients with Type 2 Diabetes Mellitus (T2DM). Presence of MetS in T2DM markedly increases the risk for coronary heart disease, stroke and premature deaths. This study was undertaken to find the prevalence of MetS and its individual components among patients with T2DM visiting Chitwan Medical College and Teaching Hospital, Bharat­pur, Nepal. Methods: A laboratory-based descriptive cross sectional study carried out at CMC-TH between January and August, 2017. Data obtained in­cluded anthropometric indices, blood pressure and fasting serum lipid profile. National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria were used for diagnosis of MetS. Data was ana­lyzed using SPSS version 20. Results: The overall prevalence of MetS among 150 T2DM patients (Mean age= 53.70±10.83 years, Male:Female=84:66) was 60%. The prev­alence was higher in females compared to males (75.75% vs.47.62%, P<0.001). High blood pressure was the commonest MetS component. Following that, decreased HDL-c was the predominant component in females whereas raised triglyceride in the males. SBP/DBP, BMI and waist circumference were significantly associated with MetS. Conclusion: The prevalence of MetS is high in diabetic patients, particu­larly in females and middle age group adults, with high blood pressure and hypertriglyceridemia as the commonest abnormalities. As MetS adds to the cardiovascular risk to the already at-risk diabetic popula­tion, timely identification and appropriate intervention is of utmost im­portance in reduction of disease burden in T2DM patients.


2020 ◽  
Vol 7 (3) ◽  
pp. 497
Author(s):  
Aishhwarrya Umeshchandara G. ◽  
Ravi K.

Background: Anemia is more frequent and severe in diabetics compared to non-diabetic patients. Chronic anemia results in tissue hypoxia, which is known to play a key role in diabetes-associated organ damage. Hence it is important to diagnose and correct anemia in diabetic patients. This study was done to elucidate the effect of glycemic control on haemoglobin levels in patients with type 2 Diabetes mellitus.Methods: The present study is an observational, cross sectional study conducted between November 2017 to May 2019 carried out in hospitals attached to Bangalore Medical college and Research Institute. A sample of 60 patients with Diabetes mellitus were included, out of which 28 were female and 32 were male patients.Results: Study was conducted on 60 patients, the age distribution was between 29yrs to 88yrs with mean age was 56±11yrs. Out of 60 patients 23 patients had anemia. There was slight positive correlation between haemoglobin percentage and HbA1c. But this was not statistically significant.Conclusions: The study concludes that Glycemic control was not found to influence the Haemoglobin levels in patients with Type 2 diabetes mellitus in a significant manner. In subjects with anemia, multiple other issues need to be addressed for improvement in haematocrit value and prevention of complications of diabetes apart from glycemic control.


2015 ◽  
Vol 10 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Fayeza Karim ◽  
Qazi Shamima Akter ◽  
Shamima Jahan ◽  
Afruza Khanom ◽  
Samira Haque ◽  
...  

Background: Complication of diabetes mellitus (DM) includes coagulation impairment. Hypercoagulable state in patient with DM may accelerate thromboembolic risk for cardiovascular disease (CVD).Objective: To assess Prothrombin Time and Activated Partial Thromboplastin Time in type 2 diabetes mellitus for observing their coagubility status.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2013 to June 2014. One hundred male patients with type 2 diabetes mellitus aged 40-60 years and one hundred age, BMI matched healthy subjects were included as control in this study. Patients were selected from BIRDEM, Dhaka. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) were estimated by auto analyzer. For statistical analysis unpaired student’t test was used.Results: In this study PT and APTT were significantly (P<0.001) lower in diabetes mellitus than those of control group.Conclusion: From this study, it may be concluded that diabetic patients are prone to develop coagulation impairment.Bangladesh Soc Physiol. 2015, June; 10(1): 26-29


2019 ◽  
Vol 18 (2) ◽  
pp. 36-41
Author(s):  
Dipesh Shakya ◽  
Vijay KC

Introduction: Diabetes mellitus is associated with various metabolic disorders, which leads to the progression of the disease and its complications. The aim of the study is to find out prevalence of metabolic syndrome and its association with the components and demographic variables. Methods: This cross-sectional study was conducted among diabetes mellitus patients at a Tertiary level teaching hospital over a period of one year (April 2015 to March 2016). The study involved the use of a questionnaire to obtain information on diabetes by performing anthropometric measurements and corroborating it with respective blood samples collected for the measurement of biochemical parameters, fasting blood glucose and lipid profile. Metabolic syndrome was defined according to the current guidelines, revised in 2005 by the National Heart, Lung and Blood Institute and the American Heart Association. Statistical Package for the Social Sciences Version 20 was used as a tool for statistical analysis. Results: This cross-sectional study involved 200 type 2 diabetes mellitus patients. The prevalence of metabolic syndrome was 71% in the studied Nepalese population. Central obesity (77.5%) and hypertension (76.8%) were the commonest risk factors. It was followed by dyslipidemia among which 65.5% had high triglyceride level and 50.7% had low level of high density lipoprotein cholesterol. Higher prevalence of metabolic syndrome was seen in male patients with type 2 diabetes which accounted for 84 (73.3%). Three components of metabolic syndrome were seen among 70 (35%) and five components among 29 (14.5%) patients. Among the patients who were studied, the age group 45 to 54, 55 to 64 and 65 to 74 years had 14 (20%), 20 (28.6%) and 19 (27.1%) of more than three components of metabolic syndrome respectively. Conclusions: The prevalence of metabolic syndrome was 71% among the patients with type 2 diabetes, where high prevalence was seen among males. In our study central obesity and hypertension along with increasing age were the most common component causing metabolic syndrome.  


Author(s):  
Poornima M. P. ◽  
Padmaja R. Walvekar

Background: The burden of diabetes mellitus is expected to increase by 58%, from 51 million people in 2010 to 87 million in 2030. In rural India the prevalence rate has increased from 1% to 4-10% over last 20 years. Objective of the study is to know the prevalence of type 2 diabetes mellitus among adults aged between 30 to 60 years residing in rural area.Methods: This community based cross-sectional study was carried out Agasga, the rural field practice area of Dept. of Community Medicine, among 855 adults aged between 30-60 years by using a predesigned & pretested schedule. Statistical analysis was done using percentages and Chi square test.Results: In this study, 67.24% participants were in age group 30-49 years, 32.74% between 50 to 60 years. 48.53% were male and 51.54% were female participants. 79% of the participants were heavy workers, 17.5% were moderate workers and rest 3.5% were sedentary type of workers. 10.9% were illiterate, and rest 91.1% was literates. 69.3% are BPL card holders. The prevalence of diabetes was 9.5%; 10.8% were at risk of getting Diabetes Mellitus. This gender wise difference in diabetes mellitus was not found to be statistically significant (p=0.986).Conclusions: With high degree of heritability, life style factor diabetes could become a major health hazard in India and this underscores the fact that prevention of diabetes must be one of the important health targets for the nation in this century. Early identification of risks will help in prevention and burden of disease. 


2020 ◽  
Vol 11 (4) ◽  
pp. 7271-7274
Author(s):  
Krithik Jain N ◽  
XavierJayseelan C

The aim of the study is to find the incidence of refractive errors in diabetic individuals. Diabetes mellitus is highly prevalent in the current world in both developing and developed countries due to the lifestyle modifications. Refractive errors of eye are a very common group of disorder associated with diabetic people leading to the impairment of vision. Hence the study of incidence of refractive errors in patients with type 2 Diabetes mellitus was conducted. It was a cross-sectional study conducted at a tertiary health care centre and following was the methodology. One hundred eyes of fifty individuals were taken into consideration from Jan 2020 to March 2020, who were affected with type 2 Diabetes mellitus. These fifty individuals underwent subjective refraction of both the eyes. The results obtained were only 17 eyes (17%) being emmetropic, remaining 83 eyes (83%) were found to be ametropic. In the 83 ametropic eyes 22 eyes (22%) were myopic, 39 eyes (39%) were hypermetropic and 22 eyes (22%) had astigmatism. In the current Cross-sectional study refractive errors were noted in 83% of individual and hypermetropia being the most common error with a prevalence of 39%.


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