scholarly journals Ocular Presentations in Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) Patients undergoing highly- active antiretroviral therapy (HAART) Therapy in Jeddah, Kingdom of Saudi Arabia.

2020 ◽  
Vol 35 (3) ◽  
Author(s):  
Muhammad Abdul Rehman Akram

Purpose: To detect the Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) related ocular manifestations in Jeddah, Saudi Arabia. Study Design: Retrospective study Place and duration of study: A one-year retrospective study was conducted in Ophthalmology Clinic of East Jeddah Hospital in the western region of the Kingdom of Saudi Arabia, during 2016-2017 Material and methods A one-year retrospective study was conducted in the Ophthalmology Clinic of East Jeddah Hospital in the western region of the Kingdom of Saudi Arabia, during 2016-2017. 47 referrals of HIV-positive patient data were collected from the Infectious Diseases Department by taking history, clinical examinations and, laboratory investigations. The ophthalmological examination included adnexal examination, bestcorrected visual acuity, intraocular pressure (IOP), anterior and posterior segment examination, B-scan and, MRI. Results Out of 47 referred patients from the In and Out-patient Departments in East Jeddah Hospital, patients presented as follows: Single patient cases of retinal necrosis, anterior uveitis and neovascular glaucoma, with pterygium,sixth nerve palsy, bacterial conjunctivitis and, adenoviral conjunctivitis. Two cases presented with HIV microangiopathy, blepharitis, cortical blindness after brain abscess, herpes infection, Kaposi sarcoma and, cytomegalovirus (CMV) retinitis. Three patients presented with tuberculosis meningitis, and six with dry eyes. Eight patients presented with cataracts, and ten with refractive errors. Conclusions Ocular manifestations of HIV infection are relatively infrequent.HAART treatment is responsible for decreasing the HIV-related complications in ophthalmology. The CD4 T-lymphocyte result can be used to predict the beginning of certain eye infections in HIV-positive patients. Hidden indicators of complications of AIDS in patients confirm the strong rationale for alternating visits with those to an ophthalmologist and professionals discussing the best treatment accordingly. Keywords: Ocular, HIV, AIDS, HAART

2021 ◽  
Vol 15 (1) ◽  
pp. 25-33
Author(s):  
Mohammed G. Alsaedi ◽  
Bader S. AlQahtani ◽  
Anhar Khalid Zahrani ◽  
Shaima E. Alshareef ◽  
Khlood A. Alzubaidy ◽  
...  

Introduction: Ocular manifestations, such as conjunctivitis, redness, and tearing, were reported in patients with Coronavirus Disease 2019 (COVID-19). Objective: To investigate the level of knowledge, attitude, and practice about the ocular manifestations of COVID-19 and protective eye measures among the general population in the western region of Saudi Arabia. Methods: A cross-sectional study was conducted over two months with 800 participants from the general population and a 39-item online structured validated questionnaire using Google Forms. The collected data were analyzed using the SPSS program version 20 and a P-value <0.05 was considered statistically significant. Results and Discussion: Among the participants (n = 800), 71.9% were females, 50% were highly educated, and 61.8% had moderate incomes. The overall mean total knowledge score was 25.185 ± 3.774, with significant differences regarding age group, gender, and income. Most of the Saudi residents with high monthly incomes, especially females, were knowledgeable regarding the ocular manifestations of COVID-19 (25.0957 ± 3.4311). The average total knowledge, attitude, and practice score was 42.1419 ± 4.833, which was average (medium level), with significant differences regarding age group, gender, and income; a high mean was obtained from the age group >50–60, females, and high-income class. Conclusion: Detailed information about the epidemiology of COVID-19 and an understanding of emerging related health issues, such as ocular manifestations, should be empowered to the public while considering the least knowledgeable groups.


2020 ◽  
Vol 31 (2) ◽  
pp. 115-119
Author(s):  
Amro Al-Hebshi ◽  
Adel Hegaze ◽  
Hesham N. Mustafa ◽  
Bayan Tash ◽  
Dana Sawan ◽  
...  

2002 ◽  
Vol 08 (06) ◽  
pp. 749-753
Author(s):  
A. A. Alrajhi ◽  
A. Nematallah ◽  
S. Abdulwahab ◽  
Z. Bukhary

Our study determined the rate of screening tuberculosis patients for HIV co-infection and the HIV seroprevalence among them. We retrospectively reviewed medical charts of 437 patients diagnosed with tuberculosis from 1995-2000 in Riyadh, Saudi Arabia. Screening was done for 178 [41%] patients: 2 [1.1%] of these were found to be HIV positive. Prior to screening, 4 patients were already known to be HIV positive. Males were screened more often than females [45% and 36% respectively]. All HIV positive patients were males. Screening was not affected by origin of the patient, history of prior tuberculosis or treatment, type of tuberculosis involvement or resistance to first line anti-tuberculosis agents. In Saudi Arabia, screening for HIV in tuberculosis patients remains underutilized. Among screened patients, seropositivity was low.


2013 ◽  
Vol 19 (6) ◽  
pp. 687-688
Author(s):  
Muna M. Baslaim ◽  
Iman H. Baroum ◽  
Noha A. Dashash ◽  
Saad A. Al-Awwad ◽  
Mohammad S. Siddiqui

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Vanessa Christinet ◽  
Eric Comte ◽  
Laura Ciaffi ◽  
Peter Odermatt ◽  
Micaela Serafini ◽  
...  

Abstract Background.  Buruli ulcer is the third most common mycobacterial disease after tuberculosis and leprosy and is particularly frequent in rural West and Central Africa. However, the impact of HIV infection on BU severity and prevalence remains unclear. Methods.  This was a retrospective study of data collected at the Akonolinga District Hospital, Cameroon, from January 1, 2002 to March 27, 2013. Human immunodeficiency virus prevalence among BU patients was compared with regional HIV prevalence. Baseline characteristics of BU patients were compared between HIV-negative and HIV-positive patients and according to CD4 cell count strata in the latter group. Buruli ulcer time-to-healing was assessed in different CD4 count strata, and factors associated with BU main lesion size at baseline were ide.jpegied. Results.  Human immunodeficiency virus prevalence among BU patients was significantly higher than the regional estimated prevalence in each group (children, 4.00% vs 0.68% [P &lt; .001]; men, 17.0% vs 4.7% [P &lt; .001]; women, 36.0% vs 8.0% [P &lt; .001]). Individuals who were HIV positive had a more severe form of BU, with an increased severity in those with a higher level of immunosuppression. Low CD4 cell count was significantly associated with a larger main lesion size (β-coefficient, −0.50; P = .015; 95% confidence interval [CI], −0.91–0.10). Buruli ulcer time-to-healing was more than double in patients with a CD4 cell count below 500 cell/mm3 (hazard ratio, 2.39; P = .001; 95% CI, 1.44–3.98). Conclusion.  Patients who are HIV positive are at higher risk for BU. Human immunodeficiency virus-induced immunosuppression seems to have an impact on BU clinical presentation and disease evolution.


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