scholarly journals Anti Obesity Action of Omega-3 Supplementation in Wistar Rats

2021 ◽  
Vol 03 (01) ◽  
pp. 68-77
Author(s):  
Silvana Macedo de Araújo ◽  
Ramon Silva Raposo ◽  
Renato Azevedo Moreira ◽  
Dinalva Brito Queiroz ◽  
Fausto Pierdoná Guzen
Keyword(s):  
Wistar Rats ◽  
Omega 3

Omega-3 fatty acids moderate oxidative and proinflammatory events in experimental hepatotoxicity in Wistar rats: comparison with livolin

Synergy ◽  
2018 ◽  
Vol 7 ◽  
pp. 17-24 ◽  
Author(s):  
Luqman Aribidesi Olayaki ◽  
Wale Johnson Adeyemi ◽  
Joseph Sunday Yinusa ◽  
Grace Amarachi Adedayo
Keyword(s):  
Fatty Acids ◽  
Wistar Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Evaluation of liver regeneration diet supplemented with omega-3 fatty acids: experimental study in rats

2015 ◽  
Vol 42 (6) ◽  
pp. 393-397 ◽  
Author(s):  
Rosilda Mendes da Silva ◽  
Osvaldo Malafaia ◽  
Orlando Jorge Martins Torres ◽  
Nicolau Gregori Czeczko ◽  
Carlos Hespanha Marinho Junior ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Liver Regeneration ◽  
Wistar Rats ◽  
Statistical Difference ◽  
Histological Study ◽  
Liver Weight ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Serum Aspartate Aminotransferase ◽  
Significant Interference

Objective: to evaluate liver regeneration in rats after partial hepatectomy of 60% with and without action diet supplemented with fatty acids through the study of the regenerated liver weight, laboratory parameters of liver function and histological study. Methods: thirty-six Wistar rats, males, adults were used, weighing between 195 and 330 g assigned to control and groups. The supplementation group received the diet by gavage and were killed after 24h, 72h and seven days. Evaluation of regeneration occurred through analysis of weight gain liver, serum aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltranspeptidase, and mitosis of the liver stained with H&E. Results: the diet supplemented group showed no statistical difference (p>0.05) on the evolution of weights. Administration of fatty acids post-hepatectomy had significant reduction in gamma glutamyltransferase levels and may reflect liver regeneration. Referring to mitotic index, it did not differ between period of times among the groups. Conclusion: supplementation with fatty acids in rats undergoing 60% hepatic resection showed no significant interference related to liver regeneration.

scholarly journals Omega 3 fatty acid and vitamin a ameliorate carrageenan-induced joint inflammation in wistar rats

2020 ◽  
Vol 58 (3) ◽  
pp. 321
Author(s):  
Ramatu Idris ◽  
Maryam Akor-dewu ◽  
Abdulrahman Abdulsamad ◽  
Fatima Ciroma ◽  
Shehu-tijani Shittu
Keyword(s):  
Fatty Acid ◽  
Vitamin A ◽  
Wistar Rats ◽  
Joint Inflammation ◽  
Omega 3 ◽  
Omega 3 Fatty Acid

scholarly journals Metabolic changes induced by pre-administration of L-alanyl-glutamine and Omega-3 in Wistar rats subjected to sepsis

2010 ◽  
Vol 25 (6) ◽  
pp. 529-534 ◽  
Author(s):  
José Ivamberg Nobre de Sena ◽  
Sérgio Botelho Guimarães ◽  
Paulo Roberto Leitão de Vasconcelos
Keyword(s):  
Energy Supply ◽  
Wistar Rats ◽  
Striated Muscle ◽  
Ketone Bodies ◽  
Saline Group ◽  
Metabolic Changes ◽  
Control Group ◽  
Omega 3 ◽  
Peripheral Tissues ◽  
Male Wistar Rats

PURPOSE: To evaluate the metabolic changes induced by pre-administration of L-alanyl-glutamine (L-Ala-Gln) and omega-3 (ω-3) in rats subjected to sepsis. METHODS: Eighteen male Wistar rats were randomized into three groups (n=6) and treated with saline (group Control-G-1), L-Ala-Gln (0.75 mg /kg , G-2) or ω-3 (0.2 g /kg, G-3 ) administered intravenously 3, 2 and 1 day and 30 minutes before induction of sepsis. Samples (blood, striated muscle and liver) were collected 48 hours after induction of sepsis, to measure the concentrations of metabolites (pyruvate, lactate, glucose and ketone bodies. RESULTS: There was a significant increase in muscle glycolysis and gluconeogenesis in the liver in rats treated with L-Ala-Gln and ω-3, compared to the control group, 48 hours after induction of sepsis. CONCLUSION: Pre-administration of L-Ala-Gln or ω-3 to rats subjected to sepsis resulted in similar metabolic changes, by rising glycolysis in peripheral tissues and stimulating hepatic gluconeogenesis and ketogenesis, resulting in increased energy supply to septic rats.

Omega-3 polyunsaturated fatty acids inhibit the accumulation of PAS-positive material in the myocardium of STZ-diabetic wistar rats

2003 ◽  
Vol 88 (2-3) ◽  
pp. 183-190 ◽  
Author(s):  
C.Lawrance Christopher ◽  
L.N Mathuram ◽  
G Genitta ◽  
I Cyrus ◽  
S Jaya Sundar
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Wistar Rats ◽  
Omega 3 ◽  
Positive Material

scholarly journals Omega-3 effects on electrocorticographic patterns of adult Wistar rats exposed to ionizing radiation

2021 ◽  
Vol 26 ◽  
pp. 100992
Author(s):  
H.G.I.F. Lima ◽  
I.M.S.S. Lopes ◽  
A.P.B. Oliveira ◽  
E.V.L. Costa ◽  
L.A.A. Aguiar ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Wistar Rats ◽  
Omega 3

scholarly journals A Study of 4G Radiofrequency Radiation effects on Juvenile Wistar Rats Cerebellum and Potential Attenuative Properties of Fish Oil Omega-3 Fat

2021 ◽  
pp. 6-19
Author(s):  
Fabiyi Oluwaseyi Sunday ◽  
Ogunbiyi Olubunmi ◽  
C. Odusote Ifeoluwa ◽  
Adelakin Lola ◽  
Olanrewaju John Afees ◽  
...  
Keyword(s):  
Fish Oil ◽  
Radiation Effects ◽  
Wistar Rats ◽  
Pubertal Development ◽  
Spatial Arrangement ◽  
Barnes Maze ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Radiofrequency Radiation ◽  
Living Organisms

Introduction: Technological devices have become a very important part of our everyday life. These electronic devices create an artificial electromagnetic field (EMF) and emit radiofrequency radiations (RFR) which have been reported to have deleterious effects on various tissues in living organisms. Fish oil is a rich source of the n-3 (also known as omega-3) fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The cerebellum plays an important role in motor control and the coordination, precision and timing of movements, as well as in motor learning. This study investigated the effect of radiofrequency radiation on the structures of the cerebellum of adolescent Wistar rats, its effect on pre-pubertal development and the potential attenuative properties of fish oil omega-3 fat. Materials and Methods: Forty (n=40) adolescent Wistar rats of approximately 35 days old were divided into five groups labelled A-E. A 4G RFR-emitting WI-FI device served as the RFR source. The 4G radiofrequency transmitter was installed at a distance of 0.5 meters from the base of the cage housing the experimental animals in each group. The fish oil was administered orally to the animals. Rats were sacrificed after 28 days of treatment and their brains harvested. The cerebellar tissues were excised and processed for histological, immunohistochemical and biochemical observations. Neurobehavioural studies including Barnes Maze and beam walk were carried out before sacrifice. Results: 4G radiofrequency radiation caused distortions in the morphology and spatial arrangement of Purkinje cells in the cerebellar tissues. It also induced neuroinflammation as marked by enhanced astrocyte reactions. Also, behavioural aberrations including negative changes in key memory parameters such as increased latency and error poke in Barnes maze assays, and increased movement parameter errors were attributable to FRR effects. Also, aberrations in neurotransmitters activities levels and vital neurochemistry enzymes were observed. The administered Omega-3 fat had an attenuative effect on the affected cortical structures, neurochemistry and selected neurobehavioural parameters.

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