scholarly journals The atopic desease development in infants and preschool children in Lesnoy town of Sverdlovsk region

2015 ◽  
Vol 12 (2) ◽  
pp. 59-63
Author(s):  
N A Volkova ◽  
I A Tuzankina ◽  
V N Shershnev
Keyword(s):  
Preschool Children ◽  
Clinical Symptoms ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Atopic Diseases ◽  
Different Types ◽  
Specific Ige Antibodies ◽  
Airborne Allergens

The aim of study. To determine the structure of atopic diseases and characterization of different allergens in their progression in infants and preschool children in Lesnoy town. Material and methods. We studied a spectrum of allergen-specific IgE antibodies in children’s blood with different allergic diseases. Comparative analysis of the results was conducted with methods of mathematical statistics. Results. Our data demonstrate the different stages of formation of atopic diseases in children. We revealed that clinical symptoms of atopic diseases and relevance of allergens were changing gradually as children were getting older. Our results showed that the role of nutrition allergens is reduced while airborne allergens came to the fore. Conclusion. Formation and progression of atopic diseases are determined by various allergens. The temporary relevance of different types of allergens indicates a diversity of multivalent sensibilization during affection of the «shock» organ; the result of this phenomenon appears as atopic march. Detection the relevant causative allergens is important for prevention of progression of allergic diseases.

scholarly journals The Importance of Diet in Predicting the Remission of Urticaria—Determination of Allergen-Specific IgE

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 679
Author(s):  
Monica Iuliana Ungureanu ◽  
Liliana Sachelarie ◽  
Radu Ciorap ◽  
Bogdan Aurelian Stana ◽  
Irina Croitoru ◽  
...  
Keyword(s):  
Predictive Value ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Egg White ◽  
Food Allergens ◽  
Pediatric Hospital ◽  
Disease Remission ◽  
Specific Serum ◽  
Different Types

Background and Objectives: Different types of food introduced gradually in the diet will expose children to different food allergens, increasing the chance of developing allergic diseases. The aim of our study was to determine if allergen-specific IgE values can influence, depending on the diet, the prediction of remission of urticaria in children. Materials and Methods: This prospective study was conducted in 132 patients diagnosed over two years with urticaria, admitted to “Sf. Maria” Clinical Pediatric Hospital Iaşi. Total IgE assay was performed by ELISA, and determination of specific serum IgE by the CLA System Quanti Scan method (Innogenetics, Heiden, Germany). Data were gathered and statistical analysis was performed using statistical software SPSS, using descriptive and inferential statistics. Results: The determination of specific IgE to food allergens was performed on a total of 132 cases. The values of specific IgE were positive for one or more food allergens in 84 patients (63.64%). The most common allergens involved were: cow’s milk in 33.3% cases, egg white in 22.6% cases, and hazelnuts in 11.9% cases. The specific IgE values for the different types of food included in our study had a predictive value for disease remission. Conclusions: The determination of specific IgE confirms the presence of a particular food allergen and may have predictive value for the future development of an allergic manifestation.

Pain and Headache

2017 ◽  
Author(s):  
E. Lee Murray ◽  
Karl E. Misulis
Keyword(s):  
Pain Management ◽  
Effective Treatment ◽  
Different Types

Pain can be classified into different types that have anatomic, physiologic, and symptomatic distinctions. Localization and characterization of the pain are essential to diagnosis. The role of the hospital neurologist in pain management is usually twofold: identify the source of the pain and advise on effective treatment.

Role of staphylococcal superantigen-specific IgE antibodies in aspirin-intolerant asthma

2006 ◽  
Vol 27 (5) ◽  
pp. 341-346 ◽  
Author(s):  
Jae-Young Lee ◽  
Hyun-Mi Kim ◽  
Yong-Min Ye ◽  
Joon-Woo Bahn ◽  
Chang-Hee Suh ◽  
...  
Keyword(s):  
Specific Ige ◽  
Ige Antibodies ◽  
Specific Ige Antibodies

On the Role of Characterization in the Design of Interfaces in Nanoscale Materials Technology

2004 ◽  
Vol 10 (3) ◽  
pp. 324-335 ◽  
Author(s):  
S.P. Ringer ◽  
K.R. Ratinac
Keyword(s):  
Three Dimensional ◽  
Atom Probe ◽  
Turbine Rotor ◽  
Clay Nanocomposites ◽  
Multimodal Approach ◽  
Transmission Electron ◽  
Different Types ◽  
And Control

This work reviews recent research on the design and control of interfaces in engineering nanomaterials. Four case studies are presented that demonstrate the power of a multimodal approach to the characterization of different types of interfaces. We have used a combination of conventional, high resolution, and analytical transmission electron microscopy, microbeam electron diffraction, and three-dimensional atom probe to study polymer–clay nanocomposites, turbine rotor steels used for power generation, multicomponent aluminum alloys, and nanocrystalline magnetic materials.

scholarly journals (a-)Topics and animacy

2021 ◽  
Author(s):  
Adriana Belletti ◽  
Claudia Manetti
Keyword(s):  
Left Periphery ◽  
Null Subjects ◽  
Object A ◽  
Syntactic Movement ◽  
Relativized Minimality ◽  
Production Experiment ◽  
Different Types ◽  
Mismatch Condition

The aim of this paper is twofold: first, we intend to contribute to the debate on the identification of the features to which syntactic locality expressed in terms of the featural Relativized Minimality/fRM principle appears to be sensitive (Rizzi 2004; Friedmann, Belletti & Rizzi 2009); second, we aim at providing a better characterization of the distributional and interpretive properties of the process of a-marking in the Topic position of the Italian left periphery identified by syntactic cartography, in relation to (in)animacy (Belletti & Manetti 2018). To these aims, we examined the role of animacy in a production experiment eliciting left dislocated topics with 5-year-old children. To the extent that a-marking is related to a kind of affectedness of object topics (Belletti 2018a), we examined whether an inanimate left dislocated object could constitute a felicitous a-Topic. Furthermore, the question whether complexity effects are modulated in the computation of fRM in an animacy mismatch condition (between an inanimate left dislocated object and an intervening (animate) lexical subject) is also addressed within the context of ClLDs. Our results show that, in the tested animacy mismatch condition, children seldom a-marked the pre-posed object. Instead, they appeared to creatively explore other solutions to overcome the production of the hard intervention structure, mainly using null subjects. As children are not ready to compute the intervention configuration with a lexical preverbal subject, but could not naturally adjust it through a-marking of the inanimate topic, they ended up opting for different types of productions in which intervention was eliminated. If the animacy feature seems to be implicated in the process of a-marking to some extent, it is not a feature to which the fRM principle is sensitive in building the object A’-dependency in ClLD: we conclude, in line with previous work, that animacy is not among the features implicated in triggering syntactic movement (in Italian).

scholarly journals The Role of Allergens in Atopic Dermatitis

2020 ◽  
Author(s):  
Suna Asilsoy ◽  
Serdar Al
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Allergic Diseases ◽  
Skin Lesions ◽  
Atopic Diseases ◽  
Chronic Skin ◽  
Genetic And Environmental Factors ◽  
Inhalant Allergens ◽  
Chronic Skin Disease

Atopic dermatitis (AD) is a chronic skin disease caused by genetic and environmental factors. Often it begins in early childhood. It is located at the first step of the process we refer to as atopic march. This feature is a precursor of the development of other allergic diseases such as asthma and allergic rhinitis. Especially in patients with atopy of food and inhalant allergens, the occurrence of other atopic diseases is more common. Although the role of these sensitivities in AD is controversial, it has been determined that some patients may trigger eczematous skin lesions. In this report, the role of allergens in atopic dermatitis are reviewed in the light of current literature.

scholarly journals Clinical manifestations of atopy in children up to two years of age

2011 ◽  
Vol 68 (8) ◽  
pp. 690-695 ◽  
Author(s):  
Nevenka Ilic ◽  
Vesna Velickovic ◽  
Dragoljub Djokic ◽  
Nebojsa Rankovic ◽  
Gordana Kostic ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Clinical Manifestations ◽  
Allergic Diseases ◽  
Developed Countries ◽  
Specific Ige ◽  
Food Allergies ◽  
Atopic Diseases ◽  
Ige Antibodies ◽  
Total Ige

Background/Aim. Atopic diseases such as atopic dermatitis, allergic rhinitis and asthma have had increased prevalence during the past decade and nowadays occur in every third child in developed countries. The aim of the study was to determine frequency and type of atopic diseases at the age of two, as well as the importance the total IgE antibodies concentrations have in diagnosis and prognosis of the disease. Methods. The study involved 175 children up to two years of age. Allergy-like symptoms were found after surveying their parents and pediatric medical records. Using the fluorescence immunossay (FIA) method, total IgE antibodies concentrations and specific IgE antibodies (Phadiatop infant) were determined on an Immunocap 100 Dyagnostic System. Results. One or more allergy-like symptoms accounted for 57.7% of findings in children under the age of two, whilst in 19.4% the existence of IgE-related allergic diseases was found. Atopic diseases usually have clinical manifestations of atopic dermatitis (11.4%), IgE-bound wheezing/asthma (10.8%) and food allergies (7.4%), and to much lesser extent those of allergic rhinitis (3.4%) and urticaria (1.7%). The significantly higher total IgE antibodies concentrations were found in children with allergy-like symptoms (p < 0.0005) (cut-off 15.15 kU/L, sensitivity 76.5% specificity 71.6%). Conclusion. Almost 20% of two-year-old children have any of clinically manifested allergic diseases, with atopic dermatitis and IgE wheeze/asthma being predominant. The higher total IgE antibodies concentration is a good marker for sensitization in children with allergy-like symptoms.

scholarly journals Molecular Targets of Fatty Acid Ethanolamides in Asthma

Medicina ◽  
2019 ◽  
Vol 55 (4) ◽  
pp. 87 ◽  
Author(s):  
Oxana Kytikova ◽  
Tatyana Novgorodtseva ◽  
Marina Antonyuk ◽  
Yulia Denisenko ◽  
Tatyana Gvozdenko
Keyword(s):  
Nervous System ◽  
Fatty Acid ◽  
Clinical Symptoms ◽  
Allergic Airway Inflammation ◽  
Molecular Targets ◽  
Allergic Diseases ◽  
Allergic Reactions ◽  
Fatty Acid Ethanolamides ◽  
System Physiology

Asthma is a common allergic pathology of the respiratory tract that requires the study of mechanisms underlying it, due to severe forms of the disease, which are refractory to therapy. The review is devoted to the search for molecular targets of fatty acid ethanolamides in asthma, in particular palmitoylethanolamide (PEA), which has been successfully used in the treatment of chronic inflammatory and neurodegenerative diseases, in the pathogenesis of which the nervous and immune systems are involved. Recently, the potentially important role of neuro-immune interactions in the development of allergic reactions has been established. Many of the clinical symptoms accompanying allergic airway inflammation are the result of the activation of neurons in the airways, so the attention of researchers is currently focused on neuro-immune interactions, which can play an important role in asthma pathophysiology. A growing number of scientific works confirm that the key molecule in the implementation of these inter-systemic interactions is nerve growth factor (NGF). In addition to its classic role in nervous system physiology, NGF is considered as an important factor associated with the pathogenesis of allergic diseases, particularly asthma, by regulating of mast cell differentiation. In this regard, NGF can be one of the targets of PEA in asthma therapy. PEA has a biological effect on the nervous system, and affects the activation and the degranulation of mast cells.

scholarly journals The Role of Substrate Temperature and Magnetic Filtering for DLC by Cathodic Arc Evaporation

Coatings ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 345 ◽  
Author(s):  
Helge Lux ◽  
Matthias Edling ◽  
Massimiliano Lucci ◽  
Julia Kitzmann ◽  
Claus Villringer ◽  
...  
Keyword(s):  
Substrate Temperature ◽  
Plasma Source ◽  
Hard Carbon ◽  
Carbon Coatings ◽  
Different Types ◽  
Cathodic Arc Evaporation ◽  
Arc Evaporation ◽  
Cathodic Arc

Diamond-like carbon (DLC) films were deposited using two different types of high current arc evaporation. The first process used a magnetic particle filter to remove droplets from the plasma. For the second process, the samples were put into a metallic cage which was placed directly above the plasma source. For both processes, we varied the substrate temperature from 21 to 350 °C in order to investigate the temperature effect. The samples were characterized using SEM, AFM, XPS, Raman Spectroscopy, Ellipsometry, Photometry, and Nano Indentation in order to compare both methods of deposition and provide a careful characterization of such DLC films. We found that the sp3 content and the hardness can be precisely adjusted by changing the substrate temperature. Furthermore, in the case of unfiltered deposition, the optical constants can be shifted in the direction of higher absorbance in order to produce black and hard carbon coatings.

Recent Developments in Crosslinking of Elastomers

2005 ◽  
Vol 78 (3) ◽  
pp. 458-488 ◽  
Author(s):  
Abi Santhosh Aprem ◽  
Kuruvilla Joseph ◽  
Sabu Thomas
Keyword(s):  
Model Compound ◽  
Network Formation ◽  
Double Network ◽  
Different Types ◽  
Recent Developments ◽  
Crosslink Densities

Abstract The recent developments in the vulcanization of elastomers, major types of crosslinking, and mechanism of crosslinking have been reviewed. Attention has been made to sum up the accelerated vulcanization. Possible mechanisms by which the reaction is taking place are discussed. The role of accelerators, activators, and fillers has been described. The different types of crosslinks and importance of each type on the specific properties of the resulting vulcanizates, etc., are discussed. Various aspects of vulcanization like model compound vulcanization, nitrosamine generation, etc., are discussed. The importance of binary accelerators and possible mechanism of their action have been mentioned. The method of double network formation, which is useful for the improvement in properties, is also described. The different methods for characterization of networks and different methods for estimating crosslink densities are also explained.

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