METASTATIC CHORIOCARCINOMA PRESENTING AS RENAL COLIC AND SKIN LESION – CASE REPORT

2021 ◽  
Vol 74 (7) ◽  
pp. 1763-1766
Author(s):  
Michał Pietrus ◽  
Adrian Czekaj ◽  
Dominik Dziadkowiak ◽  
Krzysztof Ratajczyk ◽  
Maciej Trzciniecki ◽  
...  

Choriocarcinoma is a rare malignant disease that is usually associated with a gestational event. Kidney metastasis might be misdiagnosed as renal cell carcinoma or kidney abscess. To the best of our knowledge, only 13 cases of cutaneous metastasis of choriocarcinoma have been reported in the literature so far. We report a case of choriocarcinoma that manifested with multiple metastases to the lung, skin, kidney and brain. Case report: We reported a case of a 37-year-old woman with a history of hydatiform mole, with symptoms of renal colic and abnormal findings on the skin. Chest X-ray revealed visible focal change 80 mm in diameter, located in the left lung area. The CT exposed in both kidneys multiple hypodense foci, 32 mm in size, suggesting multifocal abscesses with disruptions and perforation to paranephric area. Due to the presence of and temporary loss of vision in the right eye head CT was performed revealing metastatic changes in the brain. The diferential diagnosis between renal cancer, lung carcinoma and choriocarcinoma was achieved only after surgical removal skin lesion. This was the first time in our experience with choriocarcinoma. Immunohistochemically, the analysis was positive for beta hCG, cytokeratin AE1/AE, CK 8/18, CD10, EMA, alfa 1-inhibin and negative for protein 63, CD30 and CD117. Serum hCG level was 394590,0 mIU/mL. Conclusions: Choriocarcinoma should be taken into consideration when associated symptoms and significantly elevated blood levels of β-hCG were identified.

2021 ◽  
Vol 9 (11) ◽  
pp. 1102-1104
Author(s):  
Abderrazak Benazzouz ◽  
◽  
Yassine Karmouch ◽  
Fouad Hajji ◽  
Rachid Zaini ◽  
...  

The ovarian Vein Syndrome was first reported in 1964, yet its existence as a true pathophysiological entity remains controversial. It may present as an acute ora chronic disease, typically affecting young, multiparous women. We present in this article a 32-year-old patient with chronic renal colic, ultrasound and CT urography showing an extrinsic compression of the right lumbar ureter by the ovarian vein, a ligation, anda resection of the ovarian vein were performed by transperitoneal laparoscopy.


2015 ◽  
Vol 04 (02) ◽  
pp. 105-106
Author(s):  
S. Supadevi ◽  
Ramesh Kumar Subramanian ◽  
D. Kesavi

AbstractThe right lung has two fissures which separate the lung into three lobes. They are the oblique fissure and the horizontal fissure and the lobes are superior, middle and the inferior lobes respectively arranged from the apex of the lung to the base. In the present case, during routine dissection the right lung was observed to have complete absence of both oblique fissure and horizontal fissure and there was no lobar pattern. The lung pleural membrane was continuous from the apex to the base. Hilum structures were arranged normally. Left lung was completely normal with no variation. Variation of anatomy of lung fissures is important in case of diagnosis of lung pathologies and in the modality of treatment for segmental resection of lung.


Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1104 ◽  
Author(s):  
Lisa-Maria Kulmer ◽  
Maria Sophia Unterköfler ◽  
Hans-Peter Fuehrer ◽  
Varvara Janovska ◽  
Matus Pagac ◽  
...  

This case report is about a seven-year-old male neutered European Shorthair cat infected by Dirofilaria immitis as the first reported autochthonous Dirofilaria immitis infection in Austria. There was no history of periods abroad. Echocardiography showed suspected D. immitis in the right cardiac chamber with increased pulmonary pressure and ascites. Surgical removal of the heartworms was performed. Twenty adult heartworms were removed by transvenous jugular approach under general anesthesia and stored in 4% formalin. Five out of 20 specimens were examined via light and stereomicroscopy and feline heartworm infection was confirmed. Amplification of a 203 bp or 724 bp fragment of the cytochrome c oxidase subunit I gene was unsuccessful. After surgery the cat developed acute renal failure but recovered quickly. One year later, the cat underwent a control examination including echocardiography and blood work. There were no more D. immitis detectable at echocardiography. Lung pressure was mildly increased. Complete blood count and creatinine were unremarkable. The Knott’s test and Dirofilaria-Antigen-test produced negative results. The cat did not show any clinical signs during the follow-up period. The aim of this case report is to highlight the growing risk of acquiring infection with D. immitis not only for Austrian dogs, but also for cats. This case report represents the first report of autochthonous D. immitis infection in Austria. Moreover, even if the prognosis in cats with caval syndrome due to feline heartworm disease is guarded to poor, surgical removal of the filariae can be a successful treatment option.


2021 ◽  
Vol 100 (7) ◽  

Introduction: Primary retroperitoneal mucinous cystadenoma (PRMC) and its malignant variant – cystadenocarcinoma are extremely rare tumors known only from case studies and reviews. PRMC is a cystic tumor of the retroperitoneum, which remains asymptomatic for a long time and can reach significant proportions. It occurs mainly in women. Case report: We present the case of a 38-year-old healthy woman with diagnosed resistance in the right mesogastrium during a c-section. The delivery was terminated without a surgical intervention. The above mentioned resistance was examined further by ultrasound, computed tomography and magnetic resonance imaging. All imaging examinations showed a solid – cystic bilocular expansion, which looked like a mesenteric cyst in the right paracolic area. The patient was asymptomatic at all times, with only a palpable resistance of the abdominal wall. In November 2020, the patient underwent an elective surgery – extirpation of the cystic tumor and prophylactic appendectomy. The operation was performed classically, via midline laparotomy without perioperative perforation of the cystic tumor and without complications in the postoperative period. The histopathological examination showed a malignant variant of PRMC. So far, the patient remains free of any problems and is followed at the department of oncology. Conclusion: The goal of treatment is to achieve complete surgical removal of the tumor without its perioperative perforation. Due to the rare occurrence of the disease, there are no guidelines for the diagnosis and treatment of PRMC. Precisely because PRMC is a rare tumor, it should be part of the differential diagnosis of cystic tumors of the retroperitoneum, especially when young women are concerned.


Sarcoma ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-5
Author(s):  
Akihito Nagano ◽  
Takatoshi Ohno ◽  
Yutaka Nishimoto ◽  
Kazunari Yamada ◽  
Katsuji Shimizu

We report a case of extraskeletal osteosarcoma (ESOS) and autopsy findings. A 35-year-old man presented with an ossified tumor in the right thigh and lung metastasis. The lung tumors continued to develop despite multiagent chemotherapy and caused death within 8 months. Autopsy revealed many secondary lesions in the lungs, especially in the left lung. Histopathologically, the primary tumor and one of the secondary tumors showed proliferation of spindle-shaped tumor cells focally forming lace-like osteoid material. Therefore, we made a definite diagnosis of ESOS.


2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Zain Douba ◽  
Judy A Sinno ◽  
Haya Jawish ◽  
Nour Hakim ◽  
Abdullah Mouselli ◽  
...  

Abstract Hydatid disease (HD) is an infection with the metacestode stage of the tapeworm Echinococcus. It is commonly seen in South America, The Middle East, Eastern Mediterranean, Africa and China. Hydatid cysts usually affect the liver followed by the lungs. Involvement in other organs has been reported. However, in the majority of the cases, cysts are localized in one organ or one region. We report a rare case of a 36-year-old woman who presented to the hospital in Syria with long-standing history of non-specific abdominal pain. Computerized tomography showed several hydatid cysts in the liver, spleen, left lung, mediastinum (adjacent to the aortic arch), both breasts and above the right gluteal muscles.


2020 ◽  
Author(s):  
Lin Liu ◽  
Yini Zhang ◽  
Wei Zhang ◽  
Zhi Zhao ◽  
Zhengwei Li

Abstract Background: Choriocarcinoma is a rare and highly malignant tumor. It is characterized by the production of large amounts of human chorionic gonadotropin (HCG). The lumbar vertebrae and epidural space metastases of choriocarcinoma are extremely rare. This is a rare case report of a middle-aged woman with metastatic choriocarcinoma in the lumbar vertebrae, epidural space.Case presentation: The present case report describes a 42-year-old Chinese female patient who was admitted to the spine surgery department of The Second Afflicted Hospital of Dalian Medical University with signs of low back pain for ten days, weakness in both lower limbs and dysuria for four days in 2019. Magnetic resonance imaging revealed an inhomogeneous nodular lesion in the anterior epidural space from L3 to L4 and an abnormal signal in the L4 vertebral body. The patient underwent emergency surgery on the first day of admission for quick onset of paraplegia and dysuria. But the operation was stopped because of heavy bleeding. Five days later, she underwent endovascular embolization of the left and the right L4 lumbar segmental arteries, and after that, the hypervascular mass was subtotally removed. The histopathological diagnosis was choriocarcinoma. Then the patient received chemotherapy. But there was no apparent improvement in the neurological statement after chemotherapy. The patient’s outcome is death.Conclusions: This case suggests that choriocarcinoma should be borne in mind when observing a spinal extraosseous extension lesion with elevated β-HCG in a woman of child-bearing age.


Author(s):  
Deepankar Shukla ◽  
Nitin Bhola

Pleomorphic adenomas are benign tumour of the salivary glands that mostly affect the parotid gland. The tumor's "pleomorphic" form can be explained by its epithelial and connective tissue origins. Females between the ages of 30 and 50 are more likely to get the tumour. The tumour usually presents as asymptomatic swelling that progresses slowly. The majority of treatment is surgical removal of the tumour mass, with special attention paid to preserving the facial nerve. This is a case report of a 42-year-old female patient who had a pleomorphic adenoma of the submandibular gland. On the right side of the face, the patient had a slowly growing asymptomatic swelling. Pleomorphic adenoma is the commonest salivary gland tumor characterized by  diverse  histomorphological  features.  Early diagnosis and treatment plan entails thorough history taking, clinical examination, coupled with radiographic and histopathological findings.


2017 ◽  
Vol 9 (2) ◽  
pp. 63-65
Author(s):  
Andrija Jović ◽  
Nataša Vidović ◽  
Danijela Popović ◽  
Zorana Zlatanović ◽  
Slađana Cekić ◽  
...  

Abstract Combined nevi are melanocytic lesions composed of two or more distinct types of melanocytic populations within the same lesion. Different types of combined nevi may form bizarrely shaped, multicolored skin lesions, making them one of the greatest melanoma mimickers. We report a 48-year-old female patient with suspicious skin lesion in the left lumbar region. Clinically, there was an oval, slightly asymmetrical lesion measuring 6 x 4 mm, showing multiple colors and shades of brown and black. A dermoscopic examination revealed a brown-bluish coloration in the right part of the lesion, while a fine pigment network with perifollicular halo was found in the left part of the lesion, suggesting the diagnosis of a combined nevus. Histological examination showed a poorly circumscribed proliferation of dendritic melanocytes in the superficial and deep dermis and proliferation of melanocytes in the dermoepidermal junction. A surgical excision of the tumor was performed, in order to confirm the dermoscopic findings. In conclusion, dermoscopy is useful in differentiating combined nevi from other melanocytic lesions.


1994 ◽  
Vol 15 (1) ◽  
pp. 44-47 ◽  
Author(s):  
Masahito Hatori ◽  
Atsushi Kita ◽  
Yoshinori Hashimoto ◽  
Nikichi Watanabe ◽  
Minoru Sakurai

Ossification of the Achilles tendon is a rare condition. We recently treated a patient with ossification of bilateral Achilles tendons. The patient was a 50 year old male whose chief complaint was discomfort around the Achilles tendon. He had a previous history of treatment of bilateral club feet On the roentgenograms, the length of the bony mass in the Achilles tendon was 5.5 cm on the right side and 1.5 cm on the left side. The left side was treated by surgical removal of a bony mass and suture of the tendon. Microscopic examination of the extirpated specimen revealed bone formation through enchondral and intramembranous ossification in the Achilles tendon.


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