scholarly journals Pleomorphic Adenoma of Neck: Case Report

2021 ◽  
pp. 54-58
Author(s):  
Deepankar Shukla ◽  
Nitin Bhola
Keyword(s):  
Case Report ◽  
Pleomorphic Adenoma ◽  
Treatment Plan ◽  
Salivary Gland Tumor ◽  
Surgical Removal ◽  
Tumour Mass ◽  
Gland Tumor ◽  
Pleomorphic Adenomas ◽  
The Face ◽  
The Right

Pleomorphic adenomas are benign tumour of the salivary glands that mostly affect the parotid gland. The tumor's "pleomorphic" form can be explained by its epithelial and connective tissue origins. Females between the ages of 30 and 50 are more likely to get the tumour. The tumour usually presents as asymptomatic swelling that progresses slowly. The majority of treatment is surgical removal of the tumour mass, with special attention paid to preserving the facial nerve. This is a case report of a 42-year-old female patient who had a pleomorphic adenoma of the submandibular gland. On the right side of the face, the patient had a slowly growing asymptomatic swelling. Pleomorphic adenoma is the commonest salivary gland tumor characterized by  diverse  histomorphological  features.  Early diagnosis and treatment plan entails thorough history taking, clinical examination, coupled with radiographic and histopathological findings.

scholarly journals Giant pleomorphic adenoma of submandibular salivary gland: a case report

2019 ◽  
Vol 7 (10) ◽  
pp. 3910
Author(s):  
Nazia T. Sheikh ◽  
Rahil Muzaffar ◽  
Sumat UL Khurshid
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Submandibular Salivary Gland ◽  
Airway Compromise ◽  
Gland Tumor ◽  
Facial Disfigurement ◽  
The Right

The most common benign salivary gland tumor is the pleomorphic adenoma (PA). They can attain grotesque proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead to airway compromise. Authors report a case of a large PA arising from the right submandibular salivary gland in a 48-year-old male. The lesion measured 9cmx8cmx5cm.

scholarly journals Pleomorphic Adenoma Presenting as an Atypical Nasal Mass in a 26-Year-Old Female

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Racheal Hapunda ◽  
Chibamba Mumba ◽  
Owen Ngalamika
Keyword(s):  
Nasal Cavity ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Rare Entity ◽  
Gland Tumor ◽  
Diagnostic Dilemma ◽  
Nasal Blockage ◽  
History Of ◽  
The Right ◽  
Radiological Image

Pleomorphic adenoma (PA) is a salivary gland tumor that may rarely occur in the nasal cavity. It can be a clinical diagnostic dilemma in many instances due to many possible differential diagnoses. We report the case of a 26-year-old female who presented with a 3-year history of a right nasal growth associated with ipsilateral nasal blockage, nasal pain, and rhinorrhea. Radiological image showed a mild enhancing lesion in the right nasal cavity. The patient underwent a lateral rhinotomy with wide excision of the mass. Histopathological exam was consistent with PA. Nasal PA is a rare entity and should be suspected as a diagnosis for intranasal tumors.

scholarly journals A Rare Case of Paediatric Pleomorphic Adenoma of the Parotid Gland

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Tantry D ◽  
◽  
Chitra G ◽  
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Interesting Case ◽  
Tumour Mass ◽  
Salivary Gland Tumours ◽  
Superficial Lobe ◽  
The Face ◽  
Utmost Care ◽  
The Right

Pleomorphic adenomas are benign salivary gland tumours, which predominantly affect the superficial lobe of the parotid gland. The “pleomorphic” nature of the tumour can be explained on the basis of its epithelial and connective tissue origin. The tumour has a female predilection between 30-50 years of age. Slowly progressing asymptomatic swelling is the usual presentation of the tumour. Surgical excision of the tumour mass forms the mainstay of treatment, with utmost care taken to preserve the facial nerve. This case report aims to throw light on an interesting case of pleomorphic adenoma of the parotid gland in a 10 years old female patient. The patient presented with a slowly progressing asymptomatic swelling on the right side of the face, which was diagnosed to be pleomorphic adenoma of right parotid gland. The aim of the study is to discuss how to proceed regarding the further management.

scholarly journals Etiology and familial inheritance of pleomorphic adenomas

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
White Male ◽  
Salivary Gland Tumor ◽  
Major Salivary Gland ◽  
Gland Tumor ◽  
Superficial Lobe ◽  
Increased Risk ◽  
Pleomorphic Adenomas

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.

scholarly journals An Unusual Variant of a Common Palatal Salivary Gland Tumor: Case Report of a Pleomorphic Adenoma with Significant Lipomatous Metaplasia

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Sonal S. Shah ◽  
Tamer Zayed Moustafa
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Soft Palate ◽  
Clinical Presentation ◽  
Salivary Gland Tumor ◽  
Surgical Excision ◽  
Gland Tumor ◽  
Complete Surgical Excision ◽  
Unusual Variant ◽  
The Right

Introduction. Salivary gland tumors are relatively common in the junction of the hard and soft palate area of the oral cavity. Pleomorphic adenoma is considered the most common benign salivary gland tumor in this location. Some of the rarer subtypes of this tumor may have a misleading clinical presentation. Recognition of these variants is important since long-standing pleomorphic adenomas have the potential to become malignant. Case Presentation. A healthy 24-year-old male was referred for a painless, large, slowly growing, exophytic swelling of the right hard and soft palate. Interestingly, the lesion was yellowish in color and soft to palpation, suggestive of an innocuous lipoma or cystic lesion. An incisional biopsy was performed and the diagnosis was consistent with pleomorphic adenoma with a significant adipose tissue component. The patient was referred to an oral surgeon and underwent a complete surgical excision. Upon two-year follow-up, the patient is doing well with no recurrences. Conclusion. This case highlights a rare microscopic variant of pleomorphic adenoma with altered clinical presentation that led to an erroneous clinical diagnosis. The importance of taking a biopsy for definitive diagnosis and appropriate management is reinforced.

scholarly journals Conservative technique for the removal of implants displaced into maxillary sinus

RSBO ◽  
2020 ◽  
Vol 17 (1) ◽  
pp. 69-75
Author(s):  
Andreia Moleta ◽  
Luise Machado Brasil ◽  
Edmar Rafael de Oliveira ◽  
Suyany Gabriely Weiss ◽  
Driele Gontarz ◽  
...  
Keyword(s):  
Case Report ◽  
General Anesthesia ◽  
Maxillary Sinus ◽  
Maxillary Sinusitis ◽  
Case Reports ◽  
Treatment Plan ◽  
Surgical Removal ◽  
Left Maxillary Sinus ◽  
The Right

Displaced dental implants into the maxillary sinus are relatively rare. Treatment consists of implant surgical removal. Objective: To present two case reports of the removal of implants displaced into maxillary sinus by a conservative technique. Case report: Report 1: A 44-year-old female sought for treatment complaining about headaches and recurrent sinusitis. In the anamnesis she reported she had been undergone placement of nine maxillary implants, fifteen years ago, with total loss of those elements. At the imaging exams it was possible to observe two displaced implants into the bilateral maxillary sinus, besides radiopaque image on the left maxillary sinus, compatible with maxillary sinusitis. Based on this data, the proposed treatment plan was the removal of the displaced implants through Caldwell Luc approach and sinusotomy in the left side, under general anesthesia. The patient has a follow-up of 6 months without complaints. Report 2: A 42-year-old male was referred to the Surgery and Maxillofacial Traumatology Department for implant removal from the right maxillary sinus. Patient underwent implant installation in the area around 9 months ago. In the computarized tomography it was possible to diagnose the implant migration into the right maxillary sinus. the proposed treatment plan was the removal of the displaced implant via Caldwell Luc Access by repositioning the bony window and sinusotomy. Results: Patient has been with no complaints at 30 days after surgery. Conclusion: The technique has been shown to be effective in treating the condition.

scholarly journals A Giant Pleomorphic Adenoma of the Submandibular Salivary Gland: A Case Report

2012 ◽  
Vol 5 (3) ◽  
pp. 185-188 ◽  
Author(s):  
Colin J. Perumal ◽  
Mark Meyer ◽  
Ashraf Mohamed
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumor ◽  
Black Female ◽  
Submandibular Salivary Gland ◽  
Airway Compromise ◽  
Gland Tumor ◽  
Facial Disfigurement

The most common benign salivary gland tumor is the pleomorphic adenoma (PA). They can attain grotesque proportions and weigh several kilograms. They can cause facial disfigurement and, if untreated, could lead to airway compromise. We report a case of a large PA arising from the left submandibular salivary gland in a 20-year-old black female. The lesion measured ∼16 × 15 ×12 cm.

First Insights into the Molecular Basis of Pleomorphic Adenomas of the Salivary Glands

2000 ◽  
Vol 14 (1) ◽  
pp. 81-83 ◽  
Author(s):  
M.L. Voz ◽  
W.J.M. Van de Ven ◽  
K. Kas
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Benign Tumor ◽  
Salivary Gland Tumor ◽  
Transitional Zone ◽  
Chromosome 8 ◽  
Gland Tumor ◽  
Histopathological Classification ◽  
Pleomorphic Adenomas ◽  
Chromosomal Changes

Pleomorphic adenoma, or mixed tumor of the salivary glands, is a benign tumor originating from the major and minor salivary glands. Eighty-five percent of these tumors are found in the parotid gland, 10% in the minor (sublingual) salivary glands, and 5% in the submandibular gland. It is the most common type of salivary gland tumor, accounting for almost 50% of all neoplasms in these organs. In fact, after the first observation of recurrent loss of chromosome 22 in meningioma, this was the second type of benign tumor for which non-random chromosomal changes were reported. The rate of malignant change with the potential to metastasize has been reported to be only 2 to 3%, and only a few cases of metastasizing pleomorphic salivary gland adenomas have been described to date. The fact that these tumors arise in organs located in an ontogenetic transitional zone, a region where endoderm and ectoderm meet, might be one of the reasons for the often-problematic histopathological classification. This type of benign tumor has been cytogenetically very well-characterized, with several hundreds of tumors karyotyped. In addition to the cytogenetic subgroup with an apparently normal diploid stemline (making up approximately 30% of the cases), three major cytogenetic subgroups can be distinguished. In addition to a subgroup showing non-recurrent clonal abnormalities, another subgroup is composed of tumors with various translocations involving 12ql5. By far the largest cytogenetic subgroup, however, consists of tumors with chromosome 8 abnormalities, mainly showing translocations involving region 8ql2. The most frequently encountered aberration in this group is a t(3;8)(p21;q12).

Myoepithelial Carcinoma ex Pleomorphic Adenoma: Rare Case Report with Clinicopathologic and Immunohistochemical Features

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S86-S87
Author(s):  
M Khazaeli ◽  
Z Kamaluddin ◽  
M Taherian
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Nasal Passage ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Sublingual Gland ◽  
Myoepithelial Carcinoma ◽  
Minor Salivary Glands ◽  
Myoepithelial Differentiation ◽  
The Right

Abstract Introduction/Objective Myoepithelial carcinoma is identified by nearly exclusive myoepithelial differentiation and evidence of malignancy. It may arise de novo or in preexisting benign tumors including pleomorphic adenoma and benign myoepithelioma. It occurs most commonly in the parotid gland followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Nasopharyngeal origin has been rarely reported. Methods/Case Report An afebrile 19-year-old female presented to the emergency department with persistent facial pressure, otalgia (right side greater than left side), rhinorrhea, and several episodes of epistaxis. One month before, she has been treated with Amoxicillin for three days with no relief, where Augmentin started for her for five days. About four days prior presentation, she was placed on Prednisone and Cefdinir. Over the next several days, she began having throat pain with difficulty swallowing. Routine blood work revealed a leukocytosis of 14.2 with normal differentiation. CT of the neck showed a large soft tissue mass centered at the right nasopharynx. Flexible nasal endoscopy performed bilaterally to reveal the nasopharynx is entirely obstructed with a lobulated mass filling the nasopharynx. On the right side, it extends into the posterior nasal passage filling the sphenoethmoid recess and the posterior floor of the nasal passage. Outpatient biopsy from nasopharynx mass is also performed. Results (if a Case Study enter NA) Mass biopsy reveals a mucinous and chondromyxoid background with mixed epithelial and myoepithelial differentiation. The is squamous metaplasia of myoepithelial cells and prominent mitotic activity and apoptotic activity. Immunohistochemistry was positive for CK5/6, calponin, BCL2, SMA, BerEp4, Sox10, and a proliferative index up to 40%. Based on this information Myoepithelial Carcinoma ex-pleomorphic adenoma of the nasopharynx is the diagnosis. Conclusion Carcinoma ex pleomorphic adenoma is usually a high-grade malignancy. It occurs most commonly in the parotid gland, followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Our case is one of the few cases of myoepithelial carcinoma arising in nasopharyngeal pleomorphic adenoma.

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