Screening and Estimation of Secondary Metabolites in Leaf Extracts of Delonix elata (L.) Gamble and their Inhibitory Activities against Pathogens and Oxidative Stress

2020 ◽  
Vol 13 (3) ◽  
pp. 4918-4925
Author(s):  
M Mala ◽  
◽  
G Jeya Jothi
Keyword(s):  
Oxidative Stress ◽  
Secondary Metabolites ◽  
Leaf Extracts ◽  
Inhibitory Activities ◽  
And Oxidative Stress

scholarly journals Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress

2018 ◽  
Vol 26 (2) ◽  
pp. 778-787 ◽  
Author(s):  
Chiung-Huei Peng ◽  
Huei-Ting Lin ◽  
Dai-Jung Chung ◽  
Chien-Ning Huang ◽  
Chau-Jong Wang
Keyword(s):  
Oxidative Stress ◽  
Leaf Extracts ◽  
Mulberry Leaf ◽  
And Oxidative Stress

scholarly journals Effect of Butea monosperma leaf extracts on cyclophosphamide induced clastogenicity and oxidative stress in mice

2015 ◽  
Vol 7 (1) ◽  
pp. 85 ◽  
Author(s):  
Bimlesh Kumar ◽  
Amarjeet Singh ◽  
Mohanjit Kaur ◽  
Adarsh Choudhary
Keyword(s):  
Oxidative Stress ◽  
Leaf Extracts ◽  
Butea Monosperma ◽  
And Oxidative Stress

scholarly journals Phenolic Rich Extract fromClinacanthus nutansAttenuates Hyperlipidemia-Associated Oxidative Stress in Rats

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Nadarajan Sarega ◽  
Mustapha Umar Imam ◽  
Der-Jiun Ooi ◽  
Kim Wei Chan ◽  
Norhaizan Md Esa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Fat Diet ◽  
Protocatechuic Acid ◽  
Synergistic Effects ◽  
Leaf Extracts ◽  
Antioxidant Genes ◽  
Stress Markers ◽  
Antioxidant Capacities ◽  
Clinacanthus Nutans ◽  
And Oxidative Stress

Clinacanthus nutansis used as traditional medicine in Asia but there are limited scientific studies to support its use. In this study, the stem and leaf ofC. nutanswere extracted using solvents of differing polarities, and their antioxidant capacities were determined using multiple antioxidant assays. The water and aqueous methanolic leaf extracts were further fractionated and their antioxidant capacities and phenolic compositions were tested. Furthermore, the efficacies of the water and aqueous methanolic leaf extracts were tested against hyperlipidemia-induced oxidative stress in rats. Serum and hepatic antioxidant and oxidative stress markers were tested after feeding the rats with high fat diet together with the extracts or simvastatin for 7 weeks. The results indicated that both leaf extracts attenuated oxidative stress through increasing serum antioxidant enzymes activity and upregulating the expression of hepatic antioxidant genes. Multiple phenolic compounds were detected in the extracts and fractions ofC. nutans, although protocatechuic acid was one of the most abundant and may have contributed significantly towards the bioactivities of the extracts. However, synergistic effects of different phenolics may have contributed to the overall bioactivities.C. nutanscan be a good source of functional ingredients for the management of oxidative stress-related diseases.

Antioxidant, antihemolytic, and inhibitory activities of endemicPrimula heterochromaagainst Fe2+-induced lipid peroxidation and oxidative stress in rat brainin vitro

2012 ◽  
Vol 50 (11) ◽  
pp. 1391-1396 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahboobeh Zare ◽  
Seyed Fazel Nabavi ◽  
Alireza Naqinezhad ◽  
Seyed Mohammad Nabavi
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Inhibitory Activities ◽  
And Oxidative Stress

scholarly journals The Effect of Thaumatococcus danielli Leaf Extracts on Immunological and Oxidative Stress Markers in Rat

2021 ◽  
pp. 6-14
Author(s):  
O. B. Adu ◽  
G. A. Adeyemo ◽  
O. B. Falua ◽  
O. O. Fajana ◽  
O. O. Ogunrinola ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Cell ◽  
Petroleum Ether ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Leaf Extracts ◽  
Antioxidant Parameters ◽  
Plasma Antioxidant ◽  
And Oxidative Stress

This work demonstrated the immunological and antioxidant activities of Thaumatococcus daniellii leaf extracts and their potential as the pharmaceutical factor for the treatment of some pathological disorders such as cancer, leucopenia, cells inflammation, dietary, atherosclerosis, neurodegenerative disease and other immunological and oxidative stress disorders.36 albino rats of average weight 140 ± 5 g were randomly grouped into 6 with six rats per group. The rats in group A (positive control) received only 0.1% DMSO. The rats in the negative control (group B) received pyrogallol (immunosuppressor) + 0.1% DMSO for 7 days and challenged with 0.1ml Sheep Red Blood Cell (SRBC). The test groups (C to F) also received pyrogallol + 0.1% DMSO for 7 days and were also challenged with SRBC for a period of 72hours after which they were treated with High and Low doses of either petroleum ether or water extracts of Thaumatococcus danielii for 21days. The assessment of immunomodulatory activity was carried out using Carbon Clearance Test. Haematological/ immunological parameters, Spleen and Plasma antioxidant parameters like Catalase (CAT), Superoxide dismutase (SOD), Glutathione Peroxidase (GPX) Activities, Lipid Peroxidation (LPO) and Malonaldehyde (MDA) concentrations were also determined. Result unveiled a significant (p<0.05) increase in the phagocytic index of both high doses of water and petroleum ether extracts compared to the negative control group. There were no significant (p<0.05) changes in the Heamatological parameters and plasma catalase, but there was a significant change in the white blood cell (WBC) count and also an improvement in the spleen and plasma antioxidant parameters. Further study is required to understand the mechanism of action of both extracts in order to exploit it in immunomodulation.

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