scholarly journals APPLICATION OF “PROXELAN” SUPPOSITORY IN TREATMENT OF SYMPTOMS OF LOWER URINARY WAYS ASSOCIATED WITH CHRONIC PROSTATITE AND BENIGN HYPERPLASIA OF THE PROSTATE GLAND

Author(s):  
Юрий Заседа

Relevance. Symptoms of the lower urinary tract take a central role in outpatient urology, primarily due to the high prevalence in the general population.Objective: To analyze the eff ectiveness of suppositories “Proxelan” in the treatment of symptoms of the lower urinary tract associated with chronic prostatitis and benign prostatic hyperplasia of the mild degree.Design. The study was conducted in a prospective design on a contingent of 100 male patients who underwent outpatient treatment at the “Men’s Health Clinic” LLC. Patients were divided into 2 groups, depending on the presence in the treatment regimen of rectal suppositories “Proxelan”.Results of the study. The fi ndings on the diff erences in the intensity of symptom manifestations in the structure of lower urinary tract symptoms, according to the I-PSS scale, indicate that there is a signifi cant clinical eff ect on the symptoms in general for both treatment groups. Diff erences between the eff ect in the study groups range from moderate to minor.Conclusions. It has been established that the inclusion in the treatment regimen of rectal suppositories “Proxelan” allows to increase the clinical eff ect with respect to some indicators, namely: frequent urination and weakening of the urine stream. In addition, signifi cantly improve the quality of life of patients with symptoms of the lower urinary tract.

2020 ◽  
Vol 10 (4) ◽  
pp. 317-323
Author(s):  
Adel S. Al-Shukri ◽  
Stanislav V. Kostyukov

The results of the use of the phytopreparation Tadimax in the treatment of 60 men with mild and moderate lower urinary tract symptoms (LUTS) developed as a result of benign enlargement of the prostate gland are presented. The average age of the patients was 66.5 3.8 years. Tadimax was prescribed 2 tablets 3 times a day, in courses of 7 days with 7 day breaks for 3 months (a total of 6 courses). The data obtained indicate high efficacy and good tolerability of treatment. A decrease in the severity of LUTS was noted in 59 (96.6%) patients, which was accompanied by significant changes in objective clinical indicators: a decrease in residual urine volume and an increase in urine flow rate. Tadimax is a combined preparation, which includes extracts of several medicinal plants, and the main component is Crinum latifolium. The therapeutic effect of Tadimax is based on anti-inflammatory, antiproliferative and immunotropic action.


2016 ◽  
Vol 22 (11) ◽  
pp. 1490-1494 ◽  
Author(s):  
Jeroen R Scheepe ◽  
Yu Yi M Wong ◽  
E Daniëlle van Pelt ◽  
Immy A Ketelslegers ◽  
Coriene E Catsman-Berrevoets ◽  
...  

Neurogenic lower urinary tract dysfunction (LUTD) in multiple sclerosis (MS) is highly prevalent in adults, but has not previously been described in paediatric MS. A total of 24 consecutive children with newly diagnosed MS were prospectively assessed for bladder and bowel problems early after diagnosis. Five of 24 children (21%) showed LUTD during assessment. One of these patients did not report voiding complaints. This high prevalence of LUTD indicates that all recently diagnosed patients with paediatric MS should be evaluated early in their disease and treated for urinary problems in order to prevent potential damage to the upper urinary tract.


2013 ◽  
Vol 7 (9-10) ◽  
pp. 181 ◽  
Author(s):  
Jacques Corcos

Patients with multiple sclerosis (MS) have a very high prevalence of lower urinary tract symptoms—as many as 90% of patients with MS experience some form of voiding dysfunction and/or incontinence.1 This summary provides a brief overview of MS epidemiology, pathophysiology, the impact of the disease on patient quality of life, and the particular kinds of urinary tract abnormalities and symptoms that can present among patients with MS. Strategies to help diminish the impact of these symptoms are also discussed.


2019 ◽  
Vol 32 (04) ◽  
pp. 235-250
Author(s):  
Ruchira Sharma ◽  
Abhishek Kumar Sharma ◽  
Shishir Mathur

Abstract Background Patients with lower urinary tract infection report with unknown aetiology as a frequently encountered clinical problem. Aims To treat the patients suffering from acute symptoms of lower urinary tract infection as an add-on to standard urological care. Materials and Methods After exclusion of morphologic abnormalities, all patients with acute lower urinary tract infection who filled urinary tract infection questionnaire were offered additional homoeopathic care as an add-on to standard urological care. Standard urological care included in this study were to have adequate fluid intake to ensure the passage of 1.5 to 2 L of urine per day and maintain hygiene, especially in case of women. Symptoms were fever, incontinence, increased spasticity, decreased bladder capacity or pain, or decreased general health combined with significant bacteriuria. Seven patients were enrolled who fulfilled all the above inclusion criteria. The potencies were used according to disease grading and patient susceptibility. Descriptive statistics was used for analysis and repertory of the urinary organs and prostate gland including condylomata compiled by A.R. Morgan used for homoeopathic medicine selection. Result Seven patients were followed up for a period of 2 years. Six patients were free of urinary tract infection (UTI), whereas UTI symptoms were reduced in one patient. Conclusion Our initial experience with curing of UTI with homoeopathy according to repertory of the urinary organs and prostate gland including condylomata compiled by A.R. Morgan as add on to standard urologic care was encouraging. For an evidence-based evaluation of this concept, prospective studies are required.


2019 ◽  
pp. 184-191
Author(s):  
L. A. Sinyakova ◽  
I. V. Kosova ◽  
Y. I. Nezovibatko

Lower urinary tract infections are currently an actual clinical and social problem due to the high prevalence, the need for an interdisciplinary approach to diagnosis and treatment, the severity of the combination of disorders of urination and dyspareunia, which leads to the rejection of sexual life, violations of childbearing function. Timely and adequate diagnosis of urinary disorders in women with the identification of risk factors, concomitant diseases, pathogens allow to select a rational, primarily necessary antibacterial therapy that contributes not only to the patient’s getting rid of symptoms of the disease, but also prevents the transition of the disease into a chronic form.


Urology ◽  
2021 ◽  
Vol 25 (2) ◽  
Author(s):  
E.A. Kvyatkovsky ◽  
T.O. Kvyatkovska ◽  
E.V. Pilin

Uroflowmetry is an effective, non-invasive method for detecting lower urinary tract obstruction. However, by the nature of the uroflowgram, it is impossible to distinguish between the anatomical and functional obstruction of the urethra. The aim of the study was to develop a screening non-invasive method for the diagnosis of anatomical urethral obstruction using uroflowmetry with a pharmacourodynamic test with selective alpha-1-blocker silodosin. The study involved 235 patients aged 66.2±1.8 years (from 30 to 76 years) with symptoms of the lower urinary tract (LUTS). Uroflowmetry was performed using a “Flow-K” uroflowmeter. Ultrasound examinations of the kidneys, prostate and bladder with determination of residual urine were performed using a HONDA HS-2000 ultrasound machine. All patients underwent a pharmacourodynamic test: repeated uroflowmetry 2.5-3 hours after a single dose of 8 mg of silodosin, taking into account the pharmacodynamics of the drug. During the pharmacourodynamic test, 15 patients with obstructive or obstructive-interrupted uroflowgram had no reaction to silodosin, which was considered a positive test for anatomical (mechanical) urethral obstruction. Аn increase the maximum and average volumetric flow rate of urine during urination by 25-30%, respectively from 9.02±0.24 ml/s up to 11.69±0.32 ml/s and from 5.64±0.21 ml/s to 7.03±0.25 ml/s, were noted in 220 patients with obstructive, obstructive-interrupted obstructive-intermittent or intermittent type of uroflowgram when conducting a pharmacaurodynamic test. Such results were considered negative for anatomical (mechanical) urethral obstruction. They testified to functional obstruction of the urethra, which was subsequently successfully corrected with prescribing selective alpha-1-blockers. Patients with a positive pharmacourodynamic test were prescribed further examination using such methods as ureteroscopy, urethrocystoscopy, retrograde urethrography, to confirm the violation of the patency of the urethra or bladder neck. Urethral stricture was diagnosed in 10 patients, a calculus of the posterior urethra in 2 patients, a median lobe of the prostate gland in 3 patients with BPH. In the presence of obstructive or obstructive-interrupted uroflowgram in patients with LUTS, the pharmacourodynamic test with silodosin can be used as a screening non-invasive test to detect anatomical obstruction of the lower urinary tract.


2021 ◽  
Vol 24 (4) ◽  
pp. 62-68
Author(s):  
G. E. Roitberg ◽  
V. V. Astashov ◽  
K. G. Mkrtchyan ◽  
A. A. Lomshakov

Benign prostatic hyperplasia – one of the most common diseases in older men. The treatment strategy for benign prostatic hyperplasia consists in its drug therapy, or active surgical tactics. The indication for planned surgical treatment of benign prostatic hyperplasia is the progression of symptoms of the lower urinary tract, which are not amenable to drug correction. Men with a large prostate volume of more than 80 m3, with severe symptoms of the lower urinary tract, with a history of acute urinary retention episodes, represent a difficult group of patients in terms of choosing the tactics of surgical treatment. This article discusses the most common operations that are used in the treatment of benign prostatic hyperplasia (especially of large sizes): open adenectomy, transurethral resection of the prostate gland, enucleation of benign prostatic hyperplasia using a holmium laser, embolization of an artery of the prostate gland. Surgical treatment of benign prostatic hyperplasia requires an individual approach to the patient, taking into account his age, concomitant pathology and clinical symptoms.


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