Contribution Regarding the Use of Immunohistochimical Examination in Hemangiosarcoma

2020 ◽  
Vol 71 (8) ◽  
pp. 323-326
Author(s):  
Adrian Stancu ◽  
Romeo Teodor Cristina ◽  
Alina Ghise ◽  
Marius Pentea ◽  
Sorin Pasca ◽  
...  

A post-mortem examination of a 5-year-old female Labrador sex female was performed to find out the cause of death. The macroscopic examination revealed a large amount of blood in the abdominal cavity (hemoperitoneum) and pericardial (hemopericard) and also the rupture of the right atrium. The spleen was taken for histopathological examination.

2016 ◽  
Vol 12 (2) ◽  
pp. 9-14
Author(s):  
Mushtaq Ahmad ◽  
Md Fashiur Rahman ◽  
Farial Naima Rahman ◽  
Md Afzalur Rahman

Introduction: Post mortem examination is a process which is required to establish the exact cause of death in sudden, suspicious or unnatural cases. It determines the mode, manner and time passed since death. Objective: To explore the knowledge and attitude of 3rd year medical students regarding post mortem examination at the very beginning of their para clinical course study. Materials and Methods: This descriptive cross sectional study was performed at Armed Forces Medical College, Dhaka during the period of July to September 2016. One hundred fifteen 3rd year students were selected by purposive and convenient method and asked to respond anonymously to a 18 item selfadministered, predesigned, pretested multiple choice questionnaire which dealt with their views on autopsy practice, the knowledge procedure, attitude and perception towards post mortem examination. Ethical permission of authority concerned and verbal consent was obtained from every respondent students. Results: In this study, 108(93.91 %) students gave positive answer about the requirement of autopsy in unnatural death cases. A large number of students 57(49.56%) did not know about the types of autopsy, but more than half 67(58.26%) knew about virtual autopsy. Seventy two (62.61%) answered that heart is the organ sent for histopathological examination and majority 71(61.74%) could identify the viscera sent for chemical analysis. But most of them 65(56.52%) had wrong idea about the laboratory for chemical analysis. Also 70(60.87%) thought that formalin is used for preservation of viscera. Majority students 88(76.52%) answered that autopsy is performed to detect the cause of death. Greater part of respondent 98(85.22%) also said postmortem examination is neither harassment to victim’s relatives and nor disrespect to a dead body. Most of the students 113(98.26%) answered that observation of post mortem examination should be part of MBBS course curriculum and all 115(100%) gave positive response about utility of this chapter in their course studies. Forty one (35.65%) came to know about autopsy from medical books, followed by 35(30.44%) from newspaper/ story books. Almost all 113(98.26%) did not watch any autopsy before their admission to medical college. A greater part of students 74(64.35%) did not know whether autopsy cause any disfigurement of dead bodies. In present study 102(88.69%) students showed positive attitude to have post mortem examination of relatives if required. Majority of samples thought post mortem is not required in putrefied body and 93(80.87%) answered that body can be preserved at mortuary cooler after post mortem when required. Conclusion: Post mortem is an integral part of Forensic Medicine course curriculum. Teaching professionals should give more emphasis to make this chapter more interesting to the medical students. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 9-14


1991 ◽  
Vol 1 (2) ◽  
pp. 155-157 ◽  
Author(s):  
James P. Gnanapragasam ◽  
Allan B. Houston ◽  
Robert H. Anderson

SummaryWe describe an unusual heart in which double outlet from the left atrium resulted in atrioventricular connections to a dominant left ventricle and to a left-sided rudimentary right ventricle, while the right atrium also connected to the left ventricle. This produced, in effect, double inlet left ventricle in association with discordant atrioventricular connections. The diagnosis was made by echocardiography and confirmed at post mortem examination.


1925 ◽  
Vol 71 (295) ◽  
pp. 729-729
Author(s):  
Wm. Leonard Forsyth

Post-mortem examination of brain.—The dura and leptomeninges are normal and there is no excess of fluid. The right hemi-cranium is health. Section of the left shows a large area of rather recent hæmorrage into the substance of the white matter of the left occipital lobe. This area is confined to the white matter of the lobe, and does not communicate with either the posterior horn or the descending horn of the lateral ventricle, or the exterior.


2017 ◽  
Vol 54 (3) ◽  
pp. 546-548
Author(s):  
Adrian Stancu ◽  
Liliana Carpinisan ◽  
Alina Ghise ◽  
Marius Pentea ◽  
Delia Mira Berceanu Vaduva ◽  
...  

A post-mortem examination of an 1,5 years old Shar- Peis, dog was performed in order to find out the death cause. The macroscopically examination revealed a large amount of blood in the abdominal (hemoperitoneum) The liver was sampled for histopathological examination. Hematoxylin-eosin-methylene blue staining wasperformed in order to prepare the samples for microscopical examination. Based on the specific histopathological changes and taking into account all the pathological data, the diagnosis was liver amiloidosis.


2020 ◽  
Vol 13 (3) ◽  
pp. e233341
Author(s):  
Gillian A Corbett ◽  
Catherine O'Gorman ◽  
Waseem Kamran

Intravenous leiomyomatosis is extremely rare. This case describes a 42-year-old woman who presented with abdominal distension, cyclical bloating and urinary retention. Preoperative imaging showed a multilobulated uterine mass. Following multidisciplinary team discussion, a complete staging surgery consisting of midline laparotomy, total hysterectomy and bilateral salpingo-oophrectomy was performed. Intraoperatively, a large multilobulated uterine mass was noted with engorgement of the infundibulopelvic ligaments due to intravascular extension of tumour. On removal of the uterus, the patient desaturated and became hypotensive. Intraoperative transoesophageal echocardiography revealed mass extending from the inferior vena cava (IVC) into the right atrium (RA). The cardiothoracic surgical team retrieved a worm-like mass extending from the IVC into the RA. Histopathological examination diagnosed a large uterine leiomyoma with intravenous leiomyomatosis. The mass from the RA was a bland spindle cell tumour which matched the uterine mass histopathologically. Intravenous leiomyomatosis is a rare variant of uterine leiomyoma. Although intracardiac extension has been described, this is the first case of intraoperative embolisation of pelvic tumour to the RA at hysterectomy.


1969 ◽  
Vol 43 (1-2) ◽  
pp. 167-172
Author(s):  
Alan W. Pike

This redescription is based on specimens taken from the leg of a moorhen, Gallinula chloropus (L.), that was found alive, but paralysed, in Adwick-le-Street, Doncaster, Yorkshire. The heel joints of both legs were distended and found to be infected with nematodes. The paralysis may have been caused by debility due to blood loss as a result of injury, rather than a direct effect of the parasite because a post-mortem examination also revealed “severe bruising of the right ribs and the liver had ruptured to produce an internal haemorrhage.”


Author(s):  
Dhruba Das ◽  
Kalyan Sarma ◽  
Parimal Roychoudhury ◽  
G.E. Chethan ◽  
R. Ravindran ◽  
...  

Background: Bovine anaplasmosis is a haemolytic disease of cattle caused by an obligate intra-erythrocytic bacterium Anaplasma marginale and is characterized by high fever, dyspnoea, anaemia, icterus, decreased milk production and death. The present study was undertaken to study the gross and histopathological changes caused by naturally occurring A. marginale infection in cattle. Methods: History and clinical examination of animals revealed inappetance/anorexia, presence of tick infestation, high fever, pale or icteric mucous membranes, tachycardia, dyspnoea and lymphadenomegaly. The diagnosis of A. marginale infection was done by blood smear examination and further confirmed by polymerase chain reaction and sequencing analysis. During the present study, two animals did not respond to treatment and were succumbed to A. marginale infection. A systematic post-mortem examination was performed on the animals and gross lesions were recorded. The tissue samples from various vital organs such as heart, lungs, liver, spleen and kidneys were collected in 10% neutral buffered formalin and processed for histopathological examination. Result: The post-mortem examination revealed emaciated carcass with yellowish discoloration of serosal surfaces of the abdominal organs, haemorrhagic heart, congestion of lungs, hepatomegaly, distension of the gallbladder and splenomegaly. The major histopathological changes noticed included myocardial degeneration and necrosis, interstitial pneumonic changes, degenerative changes in hepatocytes and renal tubular epithelial cells, enlargement of red pulp area of spleen with histiocytic proliferation and hemosiderosis. Histopathology also revealed inflammatory process characterized by infiltration of mononuclear cells in various organs. Very few reports are available on the pathological aspects of A. marginale infection and thus the outcome of the present study can yield valuable information to aid in the diagnosis of bovine anaplasmosis under field conditions.


2016 ◽  
Vol 19 (6) ◽  
pp. 269 ◽  
Author(s):  
Xiaodong Li ◽  
Liping Chen ◽  
Xiumei Duan ◽  
Xiaocong Wang

Pedicled mobile thrombus in the right atrium is an extremely rare condition. Here, we described a case of a 42-year-old male hospitalized with complaints of chest pain and hemoptysis. Computed tomographic angiography of the pulmonary artery showed signs of embolism, and thoracic echocardiography indicated a pedicled mobile cloudy echo in the right atrium, which was initially suspected to be a myxoma. However, it was confirmed to be a thrombus by histopathological examination. Postoperatively, the patient was treated with anticoagulant therapy comprising of low molecular heparin and warfarin, and the patient recovered well. Thoracic echocardiography performed 3 months after surgery ruled out any recurrence of right atrial thrombus.


2019 ◽  
Vol 49 (8) ◽  
Author(s):  
Renata Dalcol Mazaro ◽  
Rafael Almeida Fighera ◽  
Flávia Serena da Luz ◽  
Alana Pivoto Herbichi

ABSTRACT: A 10-year-old male large mixed breed dog was presented with skin ulcers and fracture on the right hind limb caused by vehicle collision. Given required limb amputation, and as being a shelter senior dog, euthanasia was requested by the owner and a complete post-mortem examination was conducted immediately after death. Gross changes were consistent with marked bilateral nephromegaly. Histopathological examination of the kidneys revealed round cells filling blood vessels. Immunohistochemically, the round cells were positive for CD3 antibody. Based on these findings, in absence of involvement of the bone marrow and peripheral blood, and inexistence of primary extravascular masses, the tumor was classified as T-cell intravascular lymphoma. To the author’s knowledge, this is the first report describing intravascular lymphoma involving the kidneys alone in a dog.


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