scholarly journals Comparative Study of the Biochemical Response Behavior of Some Highly Toxic Minerals on Selenosis in Rats

2021 ◽  
Vol 72 (2) ◽  
pp. 9-18
Author(s):  
Loai Aljerf ◽  
Mike Williams ◽  
Atem Bethel Ajong ◽  
Ukaogo Prince Onydinma ◽  
Farouk Dehmchi ◽  
...  
Keyword(s):  
Scintillation Counter ◽  
Water Soluble ◽  
New Drugs ◽  
Response Behavior ◽  
Chronic Effect ◽  
Water Soluble Vitamin ◽  
Liver And Kidney ◽  
Toxic Minerals ◽  
Tissue Specimens ◽  
Potential Use

Many researchers have studied the metabolism of toxics including selenium (Se) in biological medium in rats and defined some correlations between selenium and other minerals as arsenic (As), cadmium (Cd), mercury (Hg), and thallium (Tl). An investigation of the potential influences of As, Hg, Tl and Pb on Se metabolism, which can suggest new drugs to cope the poisonousness of Se. The current study also has looked into the potential use of As(III)/As(V) toxic in the treatment of essential mineral Se in the animals (as rats) based on sequestration of these toxic elements into biologically inert complexes, reflecting the enormous interest in this subject. The acute studies have been initially achieved by shaping the pulmonary and biliary excretions of the volatile Se in neonatal masculine Holtzman rats which were injected with selenite subcutaneously in the hind flank, then the volatile Se was trapped in 8N HNO3 and the radioselenate detected in a scintillation counter. The chronic cases were carried out with the nursing of rats with a purified diet of water-soluble vitamin mix, fat-soluble vitamin mix, saccharides, oil, and salts. One week after the basic diet, the rats taken Se have received diets containing 10 ppm of the element as sodium selenite (Na2SeO3) or selenate (Na2SeO4) added in the salts. The calorimeter was used to analyze Se in the frozen tissue specimens. As, Hg, and Tl were repressed the volatized Se excreted from the lungs. As has assisted the biliary excretion of Se and inhibited the chronic selenosis. Tl has increased the retention of Se in the liver and kidney, but, had no chronic effect on the amount of Se deposited in all the studied tissues. Similarly, Hg has increased the retention of Se but in the spleen and carcass of rats indicating to the high Se concentration in blood. Hg and Tl have inhibited the Se in urine. No effects of the doses rich in As, Hg, and Tl on the Se excretion in fecal. Even though, we suggest As as a possible medication to chronic selenosis.

scholarly journals Comparative Study of the Biochemical Behavior of some Highly Toxic Minerals on Selenosis in Rats

2020 ◽  
Author(s):  
Mike Williams
Keyword(s):  
Comparative Study ◽  
Biliary Excretion ◽  
Sodium Selenite ◽  
Water Soluble ◽  
New Drugs ◽  
Chronic Effect ◽  
Basic Diet ◽  
Water Soluble Vitamin ◽  
Liver And Kidney ◽  
Toxic Minerals

Abstract Objective: An investigation of the potential influences of As, Hg, Tl and Pb on Se metabolism, which can suggest new drugs to cope the poisonousness of Se. Methods: Chronic cases were carried out with the nursing of rats with a purified diet of water-soluble vitamin mix, fat-soluble vitamin mix, saccharides, oil, and salts. One week after the basic diet, the rats taken Se have received diets containing 10 ppm of the element as sodium selenite or selenate added in the salts. Result: As, Hg, and Tl were repressed the volatized Se excreted from the lungs. As has assisted the biliary excretion of Se and inhibited the chronic selenosis. Tl has increased the retention of Se in the liver and kidney, but, had no chronic effect on the amount of Se deposited in all the studied tissues. Similarly, Hg has increased the retention of Se but in the spleen and carcass of rats indicating to the high Se concentration in blood. Hg and Tl have inhibited the Se in urine. Conclusion: No effects of the doses rich in As, Hg, and Tl on the Se excretion in fecal. Even though, we suggest As as a possible medication to chronic selenosis.

scholarly journals Water-Soluble Vitamin Levels and Supplementation in Chronic Online Hemodiafiltration Patients

2020 ◽  
Vol 5 (12) ◽  
pp. 2160-2167 ◽  
Author(s):  
Nora Schwotzer ◽  
Michiko Kanemitsu ◽  
Sebastien Kissling ◽  
Roger Darioli ◽  
Mohammed Benghezal ◽  
...  
Keyword(s):  
Water Soluble ◽  
Water Soluble Vitamin

scholarly journals Insights on Molecular Characteristics of Hydrochars by 13C-NMR and Off-Line TMAH-GC/MS and Assessment of Their Potential Use as Plant Growth Promoters

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1026 ◽  
Author(s):  
Laís G. Fregolente ◽  
João Vitor dos Santos ◽  
Giovanni Vinci ◽  
Alessandro Piccolo ◽  
Altair B. Moreira ◽  
...  
Keyword(s):  
Plant Growth ◽  
Phosphoric Acid ◽  
13C Nmr ◽  
Chemical Properties ◽  
Water Soluble ◽  
Molecular Characteristics ◽  
Initial Growth ◽  
Growth Promoters ◽  
Molecular Features ◽  
Potential Use

Hydrochar is a carbon-based material that can be used as soil amendment. Since the physical-chemical properties of hydrochar are mainly assigned to process parameters, we aimed at evaluating the organic fraction of different hydrochars through 13C-NMR and off-line TMAH-GC/MS. Four hydrochars produced with sugarcane bagasse, vinasse and sulfuric or phosphoric acids were analyzed to elucidate the main molecular features. Germination and initial growth of maize seedlings were assessed using hydrochar water-soluble fraction to evaluate their potential use as growth promoters. The hydrochars prepared with phosphoric acid showed larger amounts of bioavailable lignin-derived structures. Although no differences were shown about the percentage of maize seeds germination, the hydrochar produced with phosphoric acid promoted a better seedling growth. For this sample, the greatest relative percentage of benzene derivatives and phenolic compounds were associated to hormone-like effects, responsible for stimulating shoot and root elongation. The reactions parameters proved to be determinant for the organic composition of hydrochar, exerting a strict influence on molecular features and plant growth response.

scholarly journals Perspective: Practical Approach to Preventing Subclinical B12 Deficiency in Elderly Population

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1913
Author(s):  
Alessandra Vincenti ◽  
Laura Bertuzzo ◽  
Antonio Limitone ◽  
Giuseppe D’Antona ◽  
Hellas Cena
Keyword(s):  
Vitamin B12 ◽  
Elderly Population ◽  
Vitamin B12 Deficiency ◽  
Water Soluble ◽  
Health Issues ◽  
Animal Products ◽  
Water Soluble Vitamin ◽  
Age Dependent ◽  
B12 Deficiency ◽  
Inadequate Dietary Intake

Vitamin B12 (also known as cobalamin) is an essential water-soluble vitamin that plays a pivotal role for several physiologic functions during one’s lifespan. Only certain microorganisms are able to synthetize B12, thus humans obtain cobalamin exclusively from their diet, specifically from animal-derived foods. Specific sub-group populations are at risk of vitamin B12 subclinical deficiency due to different factors including poor intake of animal source foods and age-dependent decrease in the capacity of intestinal B12 uptake. Consumption of animal products produces some negative health issues and negatively impacts sustainability while a plant-based diet increases the risk of B12 deficiency. Taking a cue from the aforementioned considerations, this narrative review aims to summarize facts about B12 deficiency and the burden of inadequate dietary intake in elderly population, as well as to discuss sustainable approaches to vitamin B12 deficiency in aging population.

Photoactive Water-Soluble Vitamin K: A Novel Amphiphilic Photoinduced Antibacterial Agent

2021 ◽  
Author(s):  
Zheng Zhang ◽  
Nicharee Wisuthiphaet ◽  
Nitin Nitin ◽  
Luxin Wang ◽  
Ryan Kawakita ◽  
...  
Keyword(s):  
Vitamin K ◽  
Antibacterial Agent ◽  
Water Soluble ◽  
Water Soluble Vitamin
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