Effect of Acacia catechu Extract on 3T3-L1 Preadipocyte Differentiation

2016 ◽  
Vol 45 (8) ◽  
pp. 1107-1113
Author(s):  
Dong-Gyu Kim ◽  
Min Jung Kang ◽  
Hwa Jin Suh ◽  
Oh Oun Kwon ◽  
Jung Hye Shin
Keyword(s):  
Preadipocyte Differentiation ◽  
Acacia Catechu

scholarly journals Clinoptilolite Microparticles as Carriers of Catechin-Rich Acacia Catechu Extracts: Microencapsulation and In Vitro Release Study

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1655
Author(s):  
Zvezdelina Yaneva ◽  
Donika Ivanova ◽  
Nikolay Popov
Keyword(s):  
Composite System ◽  
Release Kinetics ◽  
Spectral Characteristics ◽  
In Vitro Release ◽  
Medium Ph ◽  
Release Capacity ◽  
Bioactive Substance ◽  
Acacia Catechu ◽  
Vitro Release

The main goal of the present study was to investigate the microencapsulation, in vitro release capacity and efficiency of catechin-rich Acacia catechu extract by Clinosorbent-5 (CLS-5) microparticles by in-depth detailed analyses and mathematical modelling of the encapsulation and in vitro release kinetics behaviour of the polyphenol-mineral composite system. The bioflavanol encapsulation and release efficiency on/from the mineral matrix were assessed by sorption experiments and interpretative modelling of the experimental data. The surface and spectral characteristics of the natural bioactive substance and the inorganic microcarrier were determined by Fourier Transform Infrared Spectroscopy (FTIR) and Ultraviolet/Visible (UV/Vis) spectrophotometric analyses. The maximum extent of catechin microencapsulation in acidic medium was 32%. The in vitro release kinetics study in simulated enzyme-free gastric medium (pH = 1.2) approved 88% maximum release efficiency achieved after 24 h. The in vitro release profile displayed that the developed bioflavanol/clinoptilolite microcarrier system provided sustained catechin in vitro release behaviour without an initial burst effect. Thus, the results from the present study are essential for the design and development of innovative catechin-CLS-5 microcarrier systems for application in human and veterinary medicine.

scholarly journals Dexamethasone reverses TGF-β-mediated inhibition of primary rat preadipocyte differentiation

FEBS Letters ◽  
2003 ◽  
Vol 543 (1-3) ◽  
pp. 25-30 ◽  
Author(s):  
Sun Mi Shin ◽  
Kun-yong Kim ◽  
Jae Kwang Kim ◽  
Suk Ran Yoon ◽  
Inpyo Choi ◽  
...  
Keyword(s):  
Preadipocyte Differentiation

A perceptive study on carbon sequestration potential of Acacia catechu in the Mukundara National Park Rajasthan-India

2021 ◽  
Vol 1 (3) ◽  
Author(s):  
Dr. Nidhi Chaturvedi, ◽  
Keyword(s):  
Climate Change ◽  
Carbon Sequestration ◽  
Power Law ◽  
Aboveground Biomass ◽  
National Park ◽  
Carbon Sequestration Potential ◽  
Acacia Species ◽  
Significant Function ◽  
Sequestration Potential ◽  
Acacia Catechu

The carbon sequestration potential of an unmanaged and previously unstudied Acacia catechu in the Mukundara National Park Rajasthan, by estimating the total aboveground biomass contained in the forest. It turned into observed that the biomass, above ground comprising of stems, branches, and foliage, holds a total of 200 tons per hectare, foremost to a valued 100 tons of carbon being deposited per hectare aboveground. Acacia species consequently has the potential to play a significant function within the mitigation of climate change. The relation among the biomass, M, of each component (stems, branches, and foliage) and the diameter d, of the plant become also studied, by means of fitting allometric equations of the form M = αdβ. It was observed that all components fit this power law relation very well (R2 > 0.7), chiefly the stems (R2 > 0.8) and branches (R2 > 0.9) for which the relation is found to be almost linear.

scholarly journals Irrational use of Eucalyptus oil in dentistry: a case report

1970 ◽  
Vol 10 (2) ◽  
pp. 121-124
Author(s):  
RS Shishir ◽  
C Renita ◽  
AR Kumuda ◽  
BG Subhas
Keyword(s):  
Case Report ◽  
Medical Science ◽  
Herbal Medicines ◽  
Dental Pain ◽  
Rural India ◽  
Herbal Drug ◽  
Self Medication ◽  
Eucalyptus Oil ◽  
Acacia Catechu

Use of herbal medicaments for dental pain is a practice still followed in some parts of rural India. Most often these herbal medicines are readily available to the rural without the prescription from an authorized practitioner. Eucalyptus oil is one such herbal drug which is widely used for a number of ailments. An unusual and a rare case of chemical injury secondary to the use of eucalyptus oil has been presented here. We have also described the management of the injury with herbal medication. This case report tends to highlights the dangers of self medication and also stresses on the role of herbal medications in dentistry. Keywords: Eucalyptus oil; chemical ulcers; acacia catechu; dentistry. DOI: http://dx.doi.org/10.3329/bjms.v10i2.7807 Bangladesh Journal of Medical Science Vol.10 No.2 Apr’11 pp.121-124

scholarly journals Study on Phytochemical, Antibacterial, Antioxidant and Toxicity Profile of Viscum album Linn Associated with Acacia catechu

2015 ◽  
Vol 3 (1) ◽  
pp. 60-65
Author(s):  
Meena Kusi ◽  
Kanti Shrestha ◽  
Rajani Malla
Keyword(s):  
Brine Shrimp ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Viscum Album ◽  
Biologically Active ◽  
Frap Assay ◽  
Antioxidant Power ◽  
Percolation Method ◽  
Brine Shrimp Toxicity ◽  
Acacia Catechu

This study focuses on antibacterial, antioxidant and toxic potentials of Viscum album Linn, commonly known as European mistletoe associated with Acacia catechu (Khayer in Nepali). Methanol extract of the aerial parts of the Mistletoe was prepared by cold percolation method. The resulting extract was simultaneously subjected to phytochemical screening; anti-microbial activity; anti-oxidant potential and Brine shrimp toxicity test. The major biologically active phyto-constituents observed were alkaloids, glycosides, saponins, polyphenols, flavonoids, tannins, terpenoids and cardiac glycosides. Upon antibacterial activity screening, the plant extract was found to be highly effective against Pseudomonas aeruginosa with the zone of inhibition 16±1mm compared to 17±1mm of chloramphenicol (50 mcg). The antioxidant activity as EC50 value by DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging activity was found to be 1.58 mg/ml while the ferric reducing capacity was measured to be 282.83±19.55 mg FeSO4.7H2O eqvt/g dry wt. of the extract during Ferric Ion Reducing Antioxidant Power (FRAP) Assay. The LC50 value for Brine Shrimp Toxicity Assay was found to be 31.62 ppm. This study shows the medicinal value of the mistletoe associated with Acacia catechu. Further meticulous analysis of this plant might lead to identification of active biomolecules effective as drugs for various ailmentsNepal Journal of Biotechnology. Dec. 2015 Vol. 3, No. 1: 60-65

Xanthigen Suppresses Preadipocyte Differentiation and Adipogenesis through Down-regulation of PPARγ and C/EBPs and Modulation of SIRT-1, AMPK, and FoxO Pathways

2012 ◽  
Vol 60 (4) ◽  
pp. 1094-1101 ◽  
Author(s):  
Ching-Shu Lai ◽  
Mei-Ling Tsai ◽  
Vladimir Badmaev ◽  
Miguel Jimenez ◽  
Chi-Tang Ho ◽  
...  
Keyword(s):  
Preadipocyte Differentiation ◽  
Down Regulation

MAT2B promotes adipogenesis by modulating SAMe levels and activating AKT/ERK pathway during porcine intramuscular preadipocyte differentiation

2016 ◽  
Vol 344 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Cunzhen Zhao ◽  
Xiaochang Chen ◽  
Wenjing Wu ◽  
Wusu Wang ◽  
Weijun Pang ◽  
...  
Keyword(s):  
Erk Pathway ◽  
Preadipocyte Differentiation

scholarly journals Cartilage Protection and Analgesic Activity of a Botanical Composition Comprised ofMorus alba,Scutellaria baicalensis, andAcacia catechu

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Mesfin Yimam ◽  
Teresa Horm ◽  
Laura Wright ◽  
Ping Jiao ◽  
Mei Hong ◽  
...  
Keyword(s):  
Analgesic Activity ◽  
Pain Sensitivity ◽  
Structural Integrity ◽  
Disease Model ◽  
Morus Alba ◽  
Scutellaria Baicalensis ◽  
Botanical Composition ◽  
Model Study ◽  
Associated Symptoms ◽  
Acacia Catechu

Although there have been augmented advances in drug discovery, current OA management is inadequate due to the lack of successful therapies proven to be effective in modifying disease progression. For some, the risk outweighs the benefit. As a result, there is a desperate need for safe and efficacious natural alternatives. Here we evaluated a composition fromMorus alba,Scutellaria baicalensis, andAcacia catechuin maintaining joint structural integrity and alleviating OA associated symptoms in monoiodoacetate- (MIA-) induced rat OA disease model. Study lasted for 6 weeks. 59.6%, 64.6%, 70.7%, 69.9%, and 70.3% reductions in pain sensitivity were observed for rats treated with the composition from week 1 to week 5, respectively. Statistically significant improvements in articular cartilage matrix integrity (maintained at 57.1% versus MIA + vehicle treated rats) were shown from the modified total Mankin score for animals treated with the composition. The composition showed a statistically significant reduction in uCTX-II level (54.1% reductions). The merit of combining these botanicals was also demonstrated in their synergistic analgesic activity. Therefore, the standardized blend ofMorus alba,Scutellaria baicalensis, andAcacia catechucould potentially be considered as an alternative remedy from natural sources for the management of OA and/or its associated symptoms.

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