Chất lượng giấc ngủ và các yếu tố liên quan ở bệnh nhân ung thư tại Bệnh viện Trường Đại học Y Dược Huế

2021 ◽  
Author(s):  
Mai Nguyen Phuong
Keyword(s):  
Sleep Quality ◽  
Cancer Patients ◽  
Linear Regression Analysis ◽  
Anxiety And Depression ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Related Factors ◽  
Falling Asleep

TÓM TẮT Giới thiệu: Các rối loạn về giấc ngủ: khó khăn khi đi vào giấc ngủ, duy trì giấc ngủ, chất lượng giấc ngủ kém, dậy sớm và ngủ ban ngày quá nhiều mà bệnh nhân ung thư phải trải qua thường xuyên nhưng thường hay bị bỏ sót và chưa được chú ý đến. Mục tiêu: Đánh giá chất lượng giấc ngủ và tìm hiểu các yếu tố liên quan đến chất lượng giấc ngủ ở bệnh nhân ung thư đang được điều trị tại bệnh viện trường đại học Y dược Huế. Phương pháp nghiên cứu: Phương pháp nghiên cứu cắt ngang trên 104 bệnh nhân ung thư tại Khoa Ung Bướu, bệnh viện trường Đại học Y dược Huế. Sử dụng thang đo PSQI và PHQ-ADS để đánh giá chất lượng giấc ngủ, và tình trạng trầm cảm lo âu ở bệnh nhân ung thư. Phân tích hồi quy đa biến tuyến tính dùng để kiểm định mối tương quan giữa chất lượng giấc ngủ và các yếu tố liên quan. Kết quả: Đối tượng nghiên cứu có độ tuổi trung bình 59,6 ± 11,7. Điểm PSQI trung bình chất lượng giấc ngủ là 10,6 ± 5,2. Phần lớn bệnh nhân có chất lượng giấc ngủ kém (79,8%); trong đó, 50% bệnh nhân gặp trở ngại lớn để đi vào giấc ngủ, có đến 46,2% chỉ ngủ được 5 giờ trong một đêm. Có mối liên quan có ý nghĩa thống kê giữa chất lượng giấc ngủ với giới tính và tình trạng trầm cảm, lo âu (p < 0,05). Kết luận: Bệnh nhân ung thư thường có chất lượng giấc ngủ kém. Điều này cho thấy giấc ngủ của bệnh nhân cần được quan tâm đúng mức và không nên bỏ sót trong quá trình chẩn đoán và điều trị. Từ khóa: Chất lượng giấc ngủ, bệnh nhân ung thư, trầm cảm lo âu. ABSTRACT QUALITY OF SLEEP AND RELATED FACTORS AMONG CANCER PATIENTS IN HUE UNIVERSITY HOSPITAL Introduction: Sleep disorders such as difficulty in falling asleep, maintaining sleep, poor sleep efficiency, early awakening and excessive daytime sleepiness are among the adverse effects that are experienced frequently but they are widely underdiagnosed. Therefore, addressing problems related to sleep among cancer patients could carry out better implications to improve quality of sleep, enhancing treatment outcomes. Aim: To evaluate quality of sleep and to detect associated factors of sleep quality among cancer patients. Methods: The cross-sectional study was conducted among 104 cancer patients treated at the Oncology Department, Hue University of Medicine and Pharmacy hospital. Sleep quality (Pittsburgh Sleep Quality Index), severity of anxiety and depression (Patient Health Questionnaire - Anxiety and Depression Scale) were accessed in the present study. Linear regression analysis was used to investigate the association between sleep quality and its related factors. Results: The mean age of study population was 59.6 ± 11.7. The average PSQI score was 10.6 ± 5.2. 79.8% cancer patients had poor sleep quality (PSQI score > 5). 50% patients had difficulty falling asleep and 46.2% patients reported sleep of < 5 hours per day. There were statistically associations between quality of sleep and gender, depression/anxiety (p < 0.05). Conclusion: The majority of cancer patients had poor sleep quality. This study points out that sleep is of great importance among cancer patients, which should not be neglected during the diagnosis and treatment procedure. Keyword: Quality of sleep, cancer patient, depression, anxiety.

Chất lượng giấc ngủ và các yếu tố liên quan ở bệnh nhân ung thư tại Bệnh viện Trường Đại học Y Dược Huế

2021 ◽  
Author(s):  
Xuan Dung Ho
Keyword(s):  
Sleep Quality ◽  
Cancer Patients ◽  
Linear Regression Analysis ◽  
Anxiety And Depression ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Related Factors ◽  
Falling Asleep

TÓM TẮT Giới thiệu: Các rối loạn về giấc ngủ: khó khăn khi đi vào giấc ngủ, duy trì giấc ngủ, chất lượng giấc ngủ kém, dậy sớm và ngủ ban ngày quá nhiều mà bệnh nhân ung thư phải trải qua thường xuyên nhưng thường hay bị bỏ sót và chưa được chú ý đến. Mục tiêu: Đánh giá chất lượng giấc ngủ và tìm hiểu các yếu tố liên quan đến chất lượng giấc ngủ ở bệnh nhân ung thư đang được điều trị tại bệnh viện trường đại học Y dược Huế. Phương pháp nghiên cứu: Phương pháp nghiên cứu cắt ngang trên 104 bệnh nhân ung thư tại Khoa Ung Bướu, bệnh viện trường Đại học Y dược Huế. Sử dụng thang đo PSQI và PHQ-ADS để đánh giá chất lượng giấc ngủ, và tình trạng trầm cảm lo âu ở bệnh nhân ung thư. Phân tích hồi quy đa biến tuyến tính dùng để kiểm định mối tương quan giữa chất lượng giấc ngủ và các yếu tố liên quan. Kết quả: Đối tượng nghiên cứu có độ tuổi trung bình 59,6 ± 11,7. Điểm PSQI trung bình chất lượng giấc ngủ là 10,6 ± 5,2. Phần lớn bệnh nhân có chất lượng giấc ngủ kém (79,8%); trong đó, 50% bệnh nhân gặp trở ngại lớn để đi vào giấc ngủ, có đến 46,2% chỉ ngủ được 5 giờ trong một đêm. Có mối liên quan có ý nghĩa thống kê giữa chất lượng giấc ngủ với giới tính và tình trạng trầm cảm, lo âu (p < 0,05). Kết luận: Bệnh nhân ung thư thường có chất lượng giấc ngủ kém. Điều này cho thấy giấc ngủ của bệnh nhân cần được quan tâm đúng mức và không nên bỏ sót trong quá trình chẩn đoán và điều trị. Từ khóa: Chất lượng giấc ngủ, bệnh nhân ung thư, trầm cảm lo âu. ABSTRACT QUALITY OF SLEEP AND RELATED FACTORS AMONG CANCER PATIENTS IN HUE UNIVERSITY HOSPITAL Introduction: Sleep disorders such as difficulty in falling asleep, maintaining sleep, poor sleep efficiency, early awakening and excessive daytime sleepiness are among the adverse effects that are experienced frequently but they are widely underdiagnosed. Therefore, addressing problems related to sleep among cancer patients could carry out better implications to improve quality of sleep, enhancing treatment outcomes. Aim: To evaluate quality of sleep and to detect associated factors of sleep quality among cancer patients. Methods: The cross-sectional study was conducted among 104 cancer patients treated at the Oncology Department, Hue University of Medicine and Pharmacy hospital. Sleep quality (Pittsburgh Sleep Quality Index), severity of anxiety and depression (Patient Health Questionnaire - Anxiety and Depression Scale) were accessed in the present study. Linear regression analysis was used to investigate the association between sleep quality and its related factors. Results: The mean age of study population was 59.6 ± 11.7. The average PSQI score was 10.6 ± 5.2. 79.8% cancer patients had poor sleep quality (PSQI score > 5). 50% patients had difficulty falling asleep and 46.2% patients reported sleep of < 5 hours per day. There were statistically associations between quality of sleep and gender, depression/anxiety (p < 0.05). Conclusion: The majority of cancer patients had poor sleep quality. This study points out that sleep is of great importance among cancer patients, which should not be neglected during the diagnosis and treatment procedure. Keyword: Quality of sleep, cancer patient, depression, anxiety.

Factors affecting sleep quality and its association to quality of life in adult Filipinos with cancer.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23100-e23100
Author(s):  
Amabelle Trina Borgonia Gerona ◽  
Ryelene Baquilod ◽  
Deborah A. Bernardo ◽  
Roselle B. De Guzman
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Sleep Disturbance ◽  
Cancer Patients ◽  
Advanced Disease ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Factors Affecting

e23100 Background: Sleep disturbances are highly prevalent in cancer patients and may be attributable to factors including pain, treatment side effects and psychological factors. However, the relationship between sleep and cancer is bidirectional. There is substantial evidence that sleep disturbance is associated with many aspects of cancer treatment, morbidity, mortality and quality of life. This study evaluated sleep quality in adult Filipinos with cancer and determined the association of demographic characteristics and clinical features to sleep quality. Methods: This was a cross-sectional surveillance study conducted among adult Filipinos with cancer seen at the Ambulatory Care Unit of a tertiary hospital. Questionnaires were answered to assess subjective sleep quality, pain score and quality of life. Frequency and percentages were determined. Determination of factors affecting sleep quality was analyzed using univariate and multivariate statistics. Results: Of the 406 cancer patients studied, 80% were women and the mean age was 53 years old. Majority (62%) had breast cancer. Seventy-nine percent (79%) of the patients had a PSQI score of 5 or greater, indicating poor sleep quality. Sleep among participants was characterized by prolonged time to fall asleep and shortened sleep duration. Majority reported some degree of daytime dysfunction due to poor sleep. Age, gender and marital status did not appear to affect the quality of sleep. Among disease-related factors, presence of more advanced disease, increasing pain severity and treatment with chemotherapy and/or radiotherapy were demonstrated to lead to poorer sleep quality. Surprisingly, even patients who were not receiving any active therapies (on-going surveillance) complained of sleep disturbance. Upon further investigation, poor sleep quality was shown to predict a worse quality of life among the study participants. Conclusions: Overall, the quality of sleep among adult Filipinos with cancer is significantly impaired. In particular, presence of more advanced disease, treatment with chemotherapy and radiotherapy and moderate to severe pain significantly increase the risk of having poor sleep. In turn, disturbed sleep predicted a poorer quality of life. These findings support the need to include assessment of sleep quality for a more holistic approach to cancer care.

Burden of Care and Its Relationship with Sleep Quality of Cancer Patients’ Caregivers

2021 ◽  
Author(s):  
Mohammadreza Boostaneh ◽  
Mohammad Zirak ◽  
Ramezan Fallah
Keyword(s):  
Sleep Quality ◽  
Cancer Patients ◽  
Poor Sleep ◽  
Burden Of Care ◽  
Quality Of Sleep ◽  
Study Results ◽  
Northwest Of Iran ◽  
The Mean ◽  
Convenience Sampling

Abstract Purpose: This study aimed to assess the burden of care and its relationship with sleep quality of cancer patients’ caregivers.Methods: This descriptive-correlational study was conducted in a referral center of cancer in Zanjan, northwest of Iran. 135 caregivers of cancer patients were recruited through convenience sampling method. The data were collected using a demographic characteristics questionnaire, Novak and Guest’s caregiver burden inventory and Pittsburgh sleep quality index (PSQI). The collected data was analyzed using descriptive and inferential statistics.Results: The mean (± SD) age of the participants was 39.71 (± 10.74) years. The mean (± SD) burden of care and sleep quality of the participants was 45.22 (± 17.75) and 8.88 (± 4.21), respectively. It was found that there is a significant positive relationship between burden of care and quality of sleep scores (r = 0.65, P < 0.001).Conclusion: cancer patients’ caregivers endure a remarkable burden of care and their sleep quality is undesirable. Results indicated that an increase in the burden of care reduces the caregiver’s quality of sleep. High burden of care and poor sleep quality may reduce the quality of the provided care that increase the costs and weakens the disease prognosis. According to the study results, reducing burden of care is an effective strategy regarding improving the caregivers’ quality of sleep that can improve the quality of provided cares by caregivers.

scholarly journals Quality of sleep and burnout among undergraduate medical students at the university of Nairobi, Kenya

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S279-S279
Author(s):  
Linda Nyamute ◽  
Muthoni Mathai ◽  
Anne Mbwayo
Keyword(s):  
Academic Performance ◽  
Medical Students ◽  
Sleep Quality ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Undergraduate Medical Students ◽  
Poor Sleep Quality ◽  
Significant Positive Association ◽  
The University

AimsThe main objective was to determine whether quality of sleep is associated with burnout among undergraduate medical students at the University of Nairobi.The null hypothesis in our study population was; 'There is no significant association between poor sleep quality and burnout'.BackgroundIn a pressure prevailing environment, medical students find themselves in a vicious cycle of cutting down on sleep in attempts to cope and adjust to increasing workloads. Students with poor sleep quality have been found to perform worse in their board exam and have strained social engagements. Ultimately, this chronic sleep deprivation may lead to burnout which may cause diminished sense of accomplishment and impaired professional conduct, that may be carried on to the career as a physician. High levels of burnout have been associated with suicides.MethodThe sample size obtained was 384 and participants were selected by a mixed sampling method. Data collection was through self-administered questionnaires. Scales used for this study were the Pittsburg Sleep Quality Index(PSQI) and the Oldenburg Burnout Inventory(OLBI).Ethical considerations were adhered to and approval obtained from the Kenyatta National Hospital-University of Nairobi(KNH-UON) Ethics Board. Data entry and analysis was by SPSS v23. Data from 336 questionnaires were deemed fit for analysis.ResultWith a response rate of 87.5%, the prevalence of poor sleep quality and burnout were 69.9% and 74.7% respectively. There was a significant positive association between poor sleep quality and female gender, clinical years of study, living with family, poorly perceived socio-economic state and poor subjective academic performance. In addition, being female, younger, pre-clinical years, living independently off-campus and poor subjective academic performance were significantly associated with higher levels of burnout.Burnout had a significant correlation with poor sleep quality. Daytime functioning, a component of sleep quality had the highest correlation with components of burnout, disengagement and exhaustion. Overall, 57% of the respondents had both poor sleep quality &burnout, while only 12% were good sleepers with no burnout. Furthermore, having poor sleep increased the risk of having burnout by 2.8times. It is crucial that students adopt better sleeping habits to reduce the risk of burnout.ConclusionWith the high prevalence of poor sleep quality and burnout, peer-support groups and peer-led mentorship programs are recommended within this population to help deal with expectations, challenges and difficulties encountered within the course of medical education, in addition to preparing for the early future careers.

The use of gadgets and their relationship to poor sleep quality and social interaction on mid-adolescents: a cross-sectional study

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Ilya Krisnana ◽  
Venni Hariani ◽  
Iqlima Dwi Kurnia ◽  
Yuni Sufyanti Arief
Keyword(s):  
Social Interaction ◽  
Sleep Quality ◽  
Rank Correlation ◽  
Simple Random Sampling ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
The Social

AbstractBackgroundMid-adolescents dominate the number of gadget users in Indonesia. The use of gadgets to a high intensity can cause various problems such as poor sleep quality and decreased social interaction. The purpose of this study was to analyze the relationship between the intensity of the use of gadgets and the quality of sleep and social interaction in adolescents.MethodThe research design used was a correlational research study with a cross-sectional approach. Through the calculation of the sample, the respondents were 250 adolescents who met the inclusion criteria, namely (1) adolescents aged 15–18 years and (2) teens who owned and used gadgets. The sampling method used simple random sampling by conducting a lottery system in each class. The independent variable was the intensity of using the gadget, while the dependent variable was the quality of sleep and social interaction. Data collection focused on the intensity of gadget use using questionnaires and it was analyzed using the Pittsburgh Sleep Quality Index (PSQI) and the Social Interaction Anxiety Scale (SIAS). The data was analyzed using Spearman’s rank correlation with α = 0.05.ResultsThe results showed that the intensity of gadget use was positively related to poor sleep quality in adolescents (p = <0.001; r = 0.555). The intensity of the use of gadgets was also related to social interaction with a negative direction. The higher the intensity of the use of gadgets, the lower the social interaction in adolescents (p = 0.001; r = –293).ConclusionThe use of gadgets in the mid-adolescent years is related to sleep disorders as regards the latency and duration of sleep. Adolescents are more likely to engage in social interaction and communication through gadgets than face to face.

scholarly journals The quality and characteristics of sleep of hypertensive patients

2015 ◽  
Vol 49 (4) ◽  
pp. 0596-0602 ◽  
Author(s):  
Juliét Silveira Hanus ◽  
Graziela Amboni ◽  
Maria Inês da Rosa ◽  
Luciane Bisognin Ceretta ◽  
Lisiane Tuon
Keyword(s):  
Sleep Quality ◽  
Pittsburgh Sleep Quality Index ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Registration System ◽  
Hypertensive Patients

OBJECTIVEAnalyzing the quality of sleep of hypertensive patients registered in the national registration system and monitoring of hypertensive patients.METHODSA cross-sectional study of quantitative and descriptive analyses with 280 hypertensive patients registered in the National Program of Hypertension and Diabetes of the Federal Government in the months from August to October 2011. Questionnaires were used which allowed for tracking sociodemographic data on hypertension and Pittsburgh Sleep Quality Index (PSQI).RESULTSThe prevalence of poor sleep quality among respondents (156 hypertensive patients) and high rates of using medication for sleeping (106 hypertensive patients) was observed. Other relevant data refers to the quality of sleep among hypertensive patients using sleep medication compared to those who do not use it (p≤0.01).CONCLUSIONIndividuals with high blood pressure have a negative association with sleep quality.

scholarly journals Association of Quality of Sleep and Decreased Short Term Memory Function in Medical Students of Pelita Harapan University

Medicinus ◽  
2020 ◽  
Vol 7 (7) ◽  
pp. 216
Author(s):  
Stevanie Budianto ◽  
Yusak M.T Siahaan
Keyword(s):  
Sleep Quality ◽  
Short Term Memory ◽  
Memory Function ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Short Term ◽  
Chi Square ◽  
Term Memory

<p><strong>Background:</strong> Memory is a place where information is stored from the learning process or experience. There are several types of memory , one of them is short term memory. Declining sleep quality is directly proportional to the decrease in short-term memory. Poor sleep quality is often associated with medical student due to exams or vast amount of tasks. Therefore, researcher wants to see whether there is significant correlation between sleep quality and short-term memory function in students.</p><p><strong>Aim:</strong> To assess the association of the quality of sleep towards short term memory function of medical student of Pelita Harapan University.</p><p><strong>Methods:</strong> This study was conducted with a cross-sectional method, with taking sample using the method of a simple random sample. A total of 90 respondents at University of Pelita Harapan were taken. Data collected sorted out according to the inclusion and exclusion criteria. Quality of sleep assessed with PSQI questionnaire while short-term memory assessed by Digit span backward test. Results processed with SPSS version 24 and tested with Chi Square.</p><p><strong>Results</strong>: Data analyzed by Chi square test showed there are 33 students (58.9%) have poor sleep quality and short term memory function. There are also significant association between the quality of sleep and short term memory function (p value = 0.026)</p><p><strong>Conclusion:</strong> There is significant association between the quality of sleep and short term memory function of medical students of Pelita Harapan University.</p>

scholarly journals ASSOCIATION OF SLEEP PROBLEMS AND COMMON MENTAL HEALTH PROBLEMS IN ENGINEERING STUDENTS OF SGT UNIVERSITY, GURUGRAM, INDIA

2020 ◽  
Vol 8 (12) ◽  
pp. 148-155
Author(s):  
Niyatisheokand a ◽  
◽  
Nimmi A. Jose ◽  
Abhishek Kapoor ◽  
Priya Arora ◽  
...  
Keyword(s):  
Mental Health ◽  
Sleep Quality ◽  
Engineering Students ◽  
Mental Health Problems ◽  
Sleep Problems ◽  
General Health Questionnaire ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Poor Sleep Quality

Introduction:Sleep is naturally recurring state of mind and body, characterized by altered consciousness, inhibition of nearly all voluntary muscles and reduced interactions with surroundings. Chronic disturbances can lead to poor sleep quality which may manifest as increased irritability, anxiety, tension, depression, confusion. The undergraduate years are a period of vulnerability when considering sleep problems and mental health may tend to worsen over time. Alcohol, tobacco, and stimulant beverages such as tea/ caffeine affect the quality of sleep. Students are more prone to adopt and practice maladaptive sleep hygiene such as irregular bedtime, academic pressure, internet addiction, electronic media exposure, alcohol consumption and smoking, which affects quality of sleep. Material and Methods:The study was a cross sectional, interview based, non-interventional studyconducted on the engineering students at SGT University, Budhera, Gurgaon, Haryana, India. Data was collected through questionnaires such as Pittsburgh Sleep Quality Index, The Epworth `Sleepiness Scale, Depression Anxiety Stress Scale, The general health questionnaire. Results:A total of 274 students were included in the study. The mean age was20.11 ± 1.30 years and there were more male (77.3%) students as compared to females (22.7%). Alcohol use was present in 43(11.7%) of students, cannabis intake was present in 11(4%), nicotine intake was reported by 39(14.2%) of students and only one student reported of taking opioid. DASS-A, DASS-S, DASS-D, GHQ-12, PSQI were positively correlated with each other when associations were studied individually. Conclusion:In our study,it was established that poor sleep quality in engineering students was significantly associated with poor mental and physical health.

scholarly journals Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu Memorial Hospital,2018

2020 ◽  
Author(s):  
Nebiyu Mengistu ◽  
Telake Azale ◽  
Solomon Yimer ◽  
Mahilet Fikreyesus ◽  
Elsa Melaku ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sleep Disturbance ◽  
Associated Factors ◽  
Poor Sleep ◽  
People Living With Hiv ◽  
Quality Of Sleep ◽  
Poor Sleep Quality ◽  
Living With Hiv ◽  
Hiv Aids

Abstract Background: Sleep disturbance is a common complaint in people living with HIV/AIDS. Despite the influence of sleep disturbance on treatment adherence, quality of life, work productivity, risk of chronic illness, it remains under-recognized and under-studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the knowledge gap and areas of management. The current study aimed to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods: An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint ethics committee of the University of Gondar and Amanuel Mental Specialized Hospital. Oral informed consent was obtained from each participant. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI) was computed. Results: The magnitude of poor sleep quality was 55.6%. Being female [AOR=3.40, 95% CI: (1.80, 6.41)], depression [AOR =3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR=3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR=3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR=5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR=2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR=3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality.Conclusions: More than half of the study participants were found to have poor sleep quality. A range factors influence quality of sleep of people with HIV/AIDS. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

scholarly journals The relationshipof the quality of sleep in patients with stage 5 chronickidney disease, treated with hemodialysis, with melatonin-producing function

2021 ◽  
pp. 23-30
Author(s):  
V. Ye. Кondratiuk ◽  
A. S. Petrova
Keyword(s):  
Blood Pressure ◽  
Sleep Quality ◽  
Pineal Gland ◽  
Sleep Duration ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Group I ◽  
Number Of Patients ◽  
Falling Asleep

The researcheddemonstrated the relationship between functional state of the pineal gland and sleepdeterioration. However, impaired melatonin-producing function of the pineal gland (MFE) in patients with chronic kidney disease (CKD), treated with hemodialysis (HD), and its association with sleep disturbance in this cohort of patients required further investigations.Aim — to assess the quality of sleepin patients with stage 5 CKD treated with HD and investigate itsrelationship with the pineal dysfunction.Materials and methods. Examinations involved 130 patients (50 % of men) with stage 5 CKD, treated with hemodialysis, with the mean age 58.5 [43; 66]. The day and night melatoninlevels (MT) in saliva were determined and based on the results the patients were divided into two groups: group I — 110 patients with impaired MFE, group II — 20 patients with normal MFE. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. All patients underwent clinical and laboratory tests: general and biochemical blood tests, office blood pressure (BP) measurements, Holter blood pressure monitoring.Results. Analysis of the insomniastructure in patients with stage 5 CKD, treated with HD, according to the PSQI questionnaire, demonstrated the problems with falling asleep in 96.2 % of patients, feeling of heat in 56.8 %, frequent awakenings in 52.9 %, daytime dysfunction in 40.8 %, breathing problems in 40.5 %, sleep problems due to coughing or snoring in 37.8 %, having bad dreams in 18.9 %, the use of sleeping meds in 8 % of patients. The total PSQI score in patients with impaired MFE was higher by 71.4 % (p < 0.001) compared to the value obtained in the group with preserved pineal gland function, demonstrating the effects of MFE on sleep quality.The component of «sleep delay» and «sleep duration» in patients with pineal gland dysfunction was 66.7 % higher than in the group with preserved MFE (p < 0.001). Comparative analysis of the number of minutes required for patients to fall asleep in the study groups demonstrateda greater sleep delay in HD-treated patients with impaired MFE. From them, the majority of subjects (71.8 %) needed more than 60 minutes to fall asleep, while in the group with preserved MFE such patients were not identified (p < 0.05). The number of patients with the period of falling asleep of 31 to 60 minutes in the group with pineal gland dysfunction was 30 % less than in patients with preserved MFE (p < 0.05). The number of patients in whom it took 16—30 minutes to fall asleep in the group with preserved MFE was 92.5 % (p < 0.05) more than in patients with pineal gland dysfunction, and patientswith the period of falling asleep of less than 15 minutes was by 62 % higher than patients with impaired MFE (p < 0.05). The decreased sleep duration was established in all patients treated with HD, however the most worsening of the sleep quality was revealed in the groupof MFE disorders. Thus, thenumber of patients with sleep duration < 5 hourswas by 90.8 % (р < 0.05) higher in the groupof impairedMFEvs group with the preserved MFE, with sleep duration of 5—6 hours by 81.7 % (р < 0.05), the number of subjects with duration of 6—7 hours by 76.4 % lower (р < 0.05), and those who slept > 7 hours by 84.0 % (р < 0.05).Conclusions. Patients with stage 5 CKD, treated with HD, were characterized with combination of MFE impairment (84.6 %) with poor sleep quality (86.2 %), including problems withfalling asleep, felling hot, frequent waking up, and daytime dysfunction. The low quality of sleep was determined bylow melatonin levels in saliva, the presence of hypoalbuminemia and arterial hypertension, hypertension duration and HDtreatment

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