scholarly journals Risk factors of prolonged hospital stay in children with viral severe acute respiratory infections

2014 ◽  
Vol 8 (10) ◽  
pp. 1285-1293 ◽  
Author(s):  
Amani A El Kholy ◽  
Nadia A Mostafa ◽  
Aliaa Adel Ali ◽  
Seham Awad El-Sherbini ◽  
Reem Ibrahim Ismail ◽  
...  

Introduction: Severe acute lower respiratory infections (SARIs) are one of the major causes of morbidity and mortality in young children, especially in developing countries. The present study focused on detection of risk factors for prolonged hospital stays among children with viral SARIs. Methodology: A sentinel surveillance study was conducted at Cairo University Hospital (CUH) between February 2010 and May 2011. Nasopharyngeal (NP) and oropharyngeal (OP) swabs were collected from all children admitted with SARIs. Viruses were identified using reverse transcription polymerase chain reaction (RT-PCR). Results: Out of 1,046 children, 380 (36%) were positive for one or more viruses; these included respiratory syncytial virus (RSV) (22.9%), adenovirus (6.2%), parainfluenza viruses (PIVs1-3) (5.1%), human metapneumovirus (HMPV) (4.5%), influenza A (1.4%), and influenza B (0.6%). Viral etiology was mainly detected in children under one year of age (88.9%). Prolonged length of stay was independently associated with the presence of cyanosis and underlying chronic illness (OR 7.4, CI: 1.8-30.32 [p = 0.005], OR 2.5, CI: 1.36-4.64 [p = 0.004], respectively). Virus type did not affect the length of hospital stay (p > 0.05). Oxygen therapy was required in 91% of the patients. A total of 43 patients (11.6%) required intensive care admission. Twenty-one patients (5.5%) died, and 15 of them (71.4%) had an underlying chronic illness. Conclusions: The study demonstrated the important burden of respiratory viruses as a cause of SARI in hospitalized children in a tertiary Egyptian hospital. Cyanosis and underlying chronic illness were significantly associated with prolonged length of stay.

ICU Director ◽  
2012 ◽  
Vol 3 (2) ◽  
pp. 75-79
Author(s):  
Andrew T. Young ◽  
Gebhard Wagener

Prolonged hospital length of stay after liver transplantation uses a large amount of hospital resources. The authors evaluated factors associated with prolonged hospital stay in a large single center series. Prolonged hospital stay was defined as more than 30 days. A total of 578 adult cadaveric liver transplants were included, and of these, 160 (27.7%) had a prolonged hospital stay. These patients had shorter waitlist time, higher preoperative MELD (model for end-stage liver disease) scores and received organs from donors with lower donor risk indices. In multivariate analysis, only preoperative MELD score remained significant. Postoperatively, there was no difference in the incidence of acute kidney injury; however, patients with prolonged hospital stay were more likely to have early allograft dysfunction and a higher 90-day mortality.


2019 ◽  
Vol 12 ◽  
pp. 117863611989030 ◽  
Author(s):  
Sonia Mohammad ◽  
Klaus Korn ◽  
Barbara Schellhaas ◽  
Markus F Neurath ◽  
Ruediger S Goertz

Introduction: Influenza infection is a viral disease with significant morbidity and mortality during the cold months. Clinical presentation typically includes cough, fever, and pain. Influenza disease is hardly diagnosed only on the basis of clinical symptoms due to similar clinical presentation of other diseases such as a typical cold or other flu-like diseases. We evaluated patients with proven influenza who presented at an emergency department of internal medicine in a university hospital according to the clinical presentation and different age groups. Materials and Methods: From October 2017 to April 2018, 723 reverse transcription-polymerase chain reaction (RT-PCR) tests for influenza were performed in the emergency department on patients with suspected influenza diagnosed clinically. A total of 240 influenza-positive patients were retrospectively assessed for documented main symptoms, vital parameters, risk factors for an unfavorable course, hospitalization, and death. Results: The mean age of influenza patients was 65 years. Overall, 30 patients were aged 18 to 39 years, 48 patients 40 to 59 years, and 162 patients ⩾60 years. Influenza B in 168 (70%) was predominant to 72 influenza A (mostly H1N1). In only 30% of the patients all three typical symptoms (cough, fever, and headache/myalgia) were documented. Headache or myalgia (with 34%) was rather uncommon in influenza B. Sudden onset was cited in only 5.4%; 57% of all influenza patients were in hospital for a mean of 7.1 days, and 5.8% of all influenza patients died. Patients aged above 60 years had more risk factors, showed typical symptoms less frequently, and were hospitalized longer than younger patients (<60 and <40 years). Conclusions: At an emergency department of internal medicine, influenza-diseased patients are of higher age, show an increased number of comorbidities, and are more likely to have milder symptoms documented. Elderly patients with influenza have a higher hospitalization rate with a longer hospital stay as compared with younger patients.


2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A101.3-A102
Author(s):  
Sophia Francesca Lu

BackgroundRoad traffic injuries claim are among the leading causes of preventable death, claiming around 7000 lives every year. Accordingly, injuries to the head and neck are the main causes of death and disability.ObjectiveThis aimed to identify the determinants of prolonged length of stay in the hospital among victims of road traffic injury.MethodsA retrospective cohort study was conducted. Socio-demographics, accident details (e.g. time of injury, type of victim, other party to the accident, time to admission, intoxication, and helmet use), the Glasgow Coma Score upon admission, head injuries, torso injuries, injuries to the limbs, and length of stay) were abstracted from the patient charts and cleaned accordingly. The predictor model for the determinants of prolonged length of stay in the hospital was built.ResultsThere were 427 road traffic injury victims that were admitted during the time period considered. The distribution of the time to admission differed between those who have a short length of stay and long stay differed significantly (p<0.01). Glasgow coma score, type of victim, mortality, age, and sex were found to be important determinants of prolonged hospital stay. Those who have a low Glasgow Coma Score (i.e. more severe cases) were found to be 2.77 (95% CI: 1.13–6.91) times more likely to stay longer in the hospital as compared to those who have high Score. There is strong evidence for this association. Passengers are 78% (95% CI: 0.06–0.84) less likely to stay longer in the Hospital as compared to drivers. There is also strong evidence for this association.ConclusionBased on the predictive model from 427 traffic injury patients, determinants of prolonged hospital stay were identified. Consequent policies and programs should address this.


2017 ◽  
Vol 45 (2) ◽  
pp. 691-705 ◽  
Author(s):  
Herng-Chia Chiu ◽  
Yi-Chieh Lin ◽  
Hui-Min Hsieh ◽  
Hsin-Pao Chen ◽  
Hui-Li Wang ◽  
...  

Objectives To assess the impact of minor, major and individual complications on prolonged length of hospital stay in patients with colorectal cancer (CRC) after surgery using multivariate models. Methods This was a retrospective review of data from patients who underwent surgery for stage I–III CRC at two medical centres in southern Taiwan between 2005–2010. Information was derived from four databases. Multivariate logistic regression methods were used to assess the impact of complications on prolonged length of stay (PLOS) and prolonged postoperative length of stay (PPOLOS). Results Of 1658 study patients, 251 (15.1%) experienced minor or major postsurgical complications during hospitalizations. Minor and major complications were significantly associated with PLOS (minor, odds ratio [OR] 3.59; major, OR 8.82) and with PPOLOS (minor, OR 5.55; major, OR 10.00). Intestinal obstruction, anastomosis leakage, abdominal abscess and bleeding produced the greatest impact. Conclusions Minor and major complications were stronger predictors of prolonged hospital stay than preoperative demographic and disease parameters. Compared with the PLOS model, the PPOLOS model better predicted risk of prolonged hospital stay. Optimal surgical and medical care have major roles in surgical CRC patients.


2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Amir Memon

Objectives: This study aims to scientifically fill the gap and provide the scientific data regarding risk factors associated with prolonged length of hospital stay (PLOS) in children admitted at Isra University Hospital. Study Design: Descriptive case series study. Setting: Pediatric ward of Isra University Hospital Hyderabad. Period: 22 months from February 2016 till November 2017. Material and Methods: All the children having age ≥ one year and less than 10 years hospitalized due to any cause of either gender were enrolled under this study. A proforma was designed comprising of basic demographic variables like age and gender and relevant questions like cause of hospitalization, risk factors associated with PLOS, and duration of hospital stay. All the information was noted in proforma and analyzed using SPSS version 17.0. Results: In present study we collected data of 188 children. In group A (age >1 to 5 years) there were 109 children consisted of 57.97% and remaining group B (age >6 years to 10 years) there were 79 children consisted of 42.02%. The overall mean duration of hospital stay with SD was 12.21 ± 3.14. The mean age and SD of group A was 2.33 ± 1.09 years and group B was 7.01 ± 2.39 years. Children with Group A (age ≥1 year to 5 years), Females, late seeking of medical attention, children not responding on medical treatment, and those who get infected during hospitalization were significantly associated with prolonged length of hospital stay (p <0.05). Conclusion: Younger children with age less than 5 years having female predominance and delayed seeking of medical attention were the most significant risk factors associated with PLOS in our population.


2021 ◽  
pp. 102490792110009
Author(s):  
Howard Tat Chun Chan ◽  
Ling Yan Leung ◽  
Alex Kwok Keung Law ◽  
Chi Hung Cheng ◽  
Colin A Graham

Background: Acute pyelonephritis is a bacterial infection of the upper urinary tract. Patients can be admitted to a variety of wards for treatment. However, at the Prince of Wales Hospital in Hong Kong, they are managed initially in the emergency medicine ward. The aim of the study is to identify the risk factors that are associated with a prolonged hospital length of stay. Methods: This was a retrospective cohort study conducted in Prince of Wales Hospital. The study recruited patients who were admitted to the emergency medicine ward between 1 January 2014 and 31 December 2017. These patients presented with clinical features of pyelonephritis, received antibiotic treatment and had a discharge diagnosis of pyelonephritis. The length of stay was measured and any length of stay over 72 h was considered to be prolonged. Results: There were 271 patients admitted to the emergency medicine ward, and 118 (44%) had a prolonged hospital length of stay. Univariate and multivariate analyses showed that the only statistically significant predictor of prolonged length of stay was a raised C-reactive protein (odds ratio 1.01; 95% confidence 1.01–1.02; p < 0.0001). Out of 271 patients, 261 received antibiotics in the emergency department. All 10 patients (8.5%) who did not receive antibiotics in emergency department had a prolonged length of stay (p = 0.0002). Conclusion: In this series of acute pyelonephritis treated in the emergency medicine ward, raised C-reactive protein levels were predictive for prolonged length of stay. Patients who did not receive antibiotics in the emergency department prior to emergency medicine ward admission had prolonged length of stay.


2015 ◽  
Vol 5 (9) ◽  
pp. 461-473 ◽  
Author(s):  
S. V. Kaiser ◽  
L.-A. Bakel ◽  
M. J. Okumura ◽  
A. D. Auerbach ◽  
J. Rosenthal ◽  
...  

Author(s):  
Montaha Al-Iede ◽  
Lena Sarhan ◽  
Leen Abushanab ◽  
Tamara Ayasrah ◽  
Rafaa Al Maani ◽  
...  

Background: Influenza virus and other respiratory viruses have been identified as an essential cause of acute respiratory infections (ARIs) in children worldwide. However, there are few data on its frequency and clinical presentation in Jordan. Objectives: We aimed to identify the viral etiology of acute respiratory infections and the various clinical presentations in hospitalized children, especially those with influenza viruses compared to other respiratory viruses. Methods: A retrospective study that was conducted at the Jordan university hospital. All the positive nasopharyngeal aspirates that were collected from hospitalized children aged 0-19 years from January 2017 to January 2019 were reviewed. Results: A total of 338 nasopharyngeal aspirates (NPAs) with positive viral serology results were reviewed. Among the patients younger than four years, the RSV virus was the most frequently detected. However, the Influenza B virus was the most commonly seen in patients older than 5 years, H1N1 was more frequent in autumn (29.5%), and RSV was the most frequent virus in winter. Bronchopneumonia was the most frequent diagnosis among all hospitalized patients, followed by bronchiolitis. Out of 338 patients, 50.3 % had tachypnea, 70.7% of patients were admitted to the pediatric floor, while 18.6% presented with a severe illness and required admission to the pediatric intensive care unit (PICU). Infants under the age of one were more likely to have higher co-infection rates with other viruses compared to children over five years that had influenza. Conclusion: Presentations of influenza and other respiratory viruses vary between different age groups, such as sepsis in children younger than one year.


2013 ◽  
Vol 33 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Luiz Felipe de Campos Lobato ◽  
Patrícia Cristina Alves Ferreira ◽  
Elizabeth C. Wick ◽  
Ravi P. Kiran ◽  
Feza H. Remzi ◽  
...  

2014 ◽  
Vol 66 (1) ◽  
pp. 43-50 ◽  
Author(s):  
J. Radovanov ◽  
V. Milosevic ◽  
I. Hrnjakovic ◽  
V. Petrovic ◽  
M. Ristic ◽  
...  

At present, two influenza A viruses, H1N1pdm09 and H3N2, along with influenza B virus co-circulate in the human population, causing endemic and seasonal epidemic acute febrile respiratory infections, sometimes with life-threatening complications. Detection of influenza viruses in nasopharyngeal swab samples was done by real-time RT-PCR. There were 60.2% (53/88) positive samples in 2010/11, 63.4% (52/82) in 2011/12, and 49.9% (184/369) in 2012/13. Among the positive patients, influenza A viruses were predominant during the first two seasons, while influenza B type was more active during 2012/13. Subtyping of influenza A positive samples revealed the presence of A (H1N1)pdm09 in 2010/11, A (H3N2) in 2011/12, while in 2012/13, both subtypes were detected. The highest seroprevalence against influenza A was in the age-group 30-64, and against influenza B in adults aged 30-64 and >65.


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