scholarly journals Seroprevalence of Crimean–Congo hemorrhagic fever among health care workers in a hospital in an endemic region of Turkey

2018 ◽  
Vol 12 (07) ◽  
pp. 587-591 ◽  
Author(s):  
Fatih Temocin ◽  
Hatice Köse ◽  
Tuğba Sarı ◽  
Fazilet Duygu ◽  
Ramazan Oguz Şahin
Keyword(s):  
Risk Factors ◽  
State Hospital ◽  
Hemorrhagic Fever ◽  
The Other ◽  
Central Anatolia ◽  
Endemic Region ◽  
Exact Test ◽  
Crimean Congo Hemorrhagic Fever ◽  
Contact Group ◽  
Group 2

Introduction: Crimean-Congo Hemorrhagic Fever (CCHF) can also be transmitted through unprotected contact directly with blood or body fluids as well as from laboratories. This study aimed to determine the seroprevalence of CCHF disease in the employees of the State Hospital of Yozgat Province, located in Central Anatolia of Turkey, and also to present the risk factors for healthcare workers. Methodology: A total of 112 volunteer employees of Yozgat State Hospital were included in the study. The study volunteers were divided into two groups: one having had a contact with CCHF patients and patient’s samples and the other a non-contact group. Results: In the contact group, 2 (2.9%) out of 67 subjects tested positive for anti-CCHF IgG; however, in the non-contact group, none of the subjects tested positive (Fisher's exact test p > 0.05). Of the two employees who tested positive, one was working at the microbiology laboratory and the other was from the emergency department. Conclusion: Although cases of nosocomial transmission of CCHF have been reported previously, questions on the mode of transmission of the disease are still unanswered. The risk factors for the disease should, therefore, be identified in order to take the necessary measures.

scholarly journals The complete genome sequence of a Crimean-Congo Hemorrhagic Fever virus isolated from an endemic region in Kosovo

2008 ◽  
Vol 5 (1) ◽  
pp. 7 ◽  
Author(s):  
Darja Duh ◽  
Stuart T Nichol ◽  
Marina L Khristova ◽  
Ana Saksida ◽  
Iva Hafner-Bratkovič ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Hemorrhagic Fever ◽  
Fever Virus ◽  
Endemic Region ◽  
Crimean Congo Hemorrhagic Fever ◽  
Hemorrhagic Fever Virus

scholarly journals Risk factors for Crimean-Congo hemorrhagic fever virus infection in Livestock in Pakistan

2019 ◽  
Vol 79 ◽  
pp. 137 ◽  
Author(s):  
K.K. Kasi ◽  
M.A. Sas ◽  
C. Sauter-Louis ◽  
J.M. Gethmann ◽  
M.H. Groschup ◽  
...  
Keyword(s):  
Risk Factors ◽  
Virus Infection ◽  
Hemorrhagic Fever ◽  
Fever Virus ◽  
Crimean Congo Hemorrhagic Fever ◽  
Hemorrhagic Fever Virus

The Importance of Supportive Care with Tranexamic Acid in Crimean-Congo Hemorrhagic Fever

Chemotherapy ◽  
2016 ◽  
Vol 61 (3) ◽  
pp. 148-151
Author(s):  
Selçuk Kaya ◽  
Firdevs Aksoy ◽  
Nurten Nur Kenç ◽  
Ahmet Eroğlu ◽  
İftihar Köksal
Keyword(s):  
Prognostic Factors ◽  
Tranexamic Acid ◽  
Supportive Care ◽  
Organ Dysfunction ◽  
Hemorrhagic Fever ◽  
Multiple Organ ◽  
Close Monitoring ◽  
Multiple Organ Dysfunction ◽  
Endemic Region ◽  
Crimean Congo Hemorrhagic Fever

This report describes a case of Crimean-Congo hemorrhagic fever with widespread hemorrhages and multiple organ dysfunction syndrome in a 46-year-old patient from an endemic region. Although the patient had numerous poor prognostic factors, he was discharged in a healthy condition after 17 days of hospitalization with close monitoring and supportive care. Tranexamic acid was successfully used together with other supportive treatments.

Risk Factors for Crimean-Congo Hemorrhagic Fever in Rural Northern Senegal

1991 ◽  
Vol 164 (4) ◽  
pp. 686-692 ◽  
Author(s):  
L. E. Chapman ◽  
M. L. Wilson ◽  
D. B. Hall ◽  
B. LeGuenno ◽  
E. A. Dykstra ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hemorrhagic Fever ◽  
Crimean Congo Hemorrhagic Fever

Crimean–Congo hemorrhagic fever in Eastern Turkey: clinical features, risk factors and efficacy of ribavirin therapy

2006 ◽  
Vol 52 (3) ◽  
pp. 207-215 ◽  
Author(s):  
Z OZKURT ◽  
I KIKI ◽  
S EROL ◽  
F ERDEM ◽  
N YILMAZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Features ◽  
Hemorrhagic Fever ◽  
Crimean Congo Hemorrhagic Fever ◽  
Eastern Turkey

scholarly journals 675. Crimean-Congo Hemorrhagic Fever Beyond Ribavirin: A Systematic Review

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S439-S440
Author(s):  
Stephanie P Fabara ◽  
Raghavendra Tirupathi ◽  
Juan Fernando Ortiz ◽  
Urvish Patel ◽  
Sashwath Srikanth ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Acute Infection ◽  
Case Series ◽  
Case Fatality ◽  
Hemorrhagic Fever ◽  
The Other ◽  
Duration Of Symptoms ◽  
Crimean Congo Hemorrhagic Fever ◽  
Significant Difference

Abstract Background The Crimean-Congo Hemorrhagic Fever (CCHF) is a tick-borne virus infection that has been reported in about 30 countries worldwide. Clinical presentation is divided into three phases: pre-hemorrhagic, hemorrhagic, and convalescence. Ribavirin is standard of care treatment for acute infection and prophylaxis. However, the use of other treatments beyond ribavirin is largely unknown. Methods We conducted a systematic review using MOOSE protocol. The inclusion and exclusion criteria are seen in the Prisma diagram. For Bias Analysis we use a Robin-1 tool. Literature review algorithm Results We gathered a total of 10 studies, which included 4 therapeutic plasma exchange (TPE), 2 corticosteroids, 2 IVIG, and 1 with convalescent plasma (CP). TPE in one study showed decreased mortality rate and increased efficacy in patients with severe CCHF. While the other study reported pulmonary embolism related to the use of TPE. Nevertheless, the patients had good outcome in the end. Two case reports used TPE plus ribavirin and supportive measures. Both were discharged home and recovered without sequela. Corticosteroids were found to be beneficial in one study were the case fatality rate was lower with the addition of corticosteroids to ribavirin in severely ill patients (p=0.0014). In a case series of six patients, who received the combination in early stages of the disease had good clinical outcomes with improved survival. IVIG was shown to increase platelet counts in two studies. In the first study, platelet count increased above 150,000/mL in 8.5 +/- 2.5 days. While in the other study the normalization of platelets was seen in 4 - 4.8 days, with no significant difference (P = 0.49). In addition, there was a decrease in the duration of symptoms but there was no statistically significant difference in mortality rates (P = 0.171). CP treatment showed a survival rate of 86% in treated patients. CP was more useful in high-risk patients, defined as having a viral load of 108 copies/mL or more. The main limitations of the studies were the sample size and heterogenicity among the outcomes of the studies. Conclusion TPE, CP, IVIG, and corticosteroids were effective in improving the clinical outcomes of the patients. The use of these treatments beyond ribavirin should be explored in future studies. Disclosures All Authors: No reported disclosures

scholarly journals Crimean Congo hemorrhagic fever in the COVID-19 pandemic: a case study

2021 ◽  
Author(s):  
Masoud Mardani ◽  
Kouros Aghazadeh ◽  
Shahriar Nikpour ◽  
Atousa Hakamifard
Keyword(s):  
Clinical Features ◽  
Viral Infections ◽  
Hemorrhagic Fever ◽  
The Other ◽  
Crimean Congo Hemorrhagic Fever ◽  
Initial Stage ◽  
Reliable Diagnosis ◽  
Tehran Province

In the COVID-19 pandemic, the overlap of clinical features between the other viral infections, make a reliable diagnosis difficult in the initial stage of illness. We describe the first confirmed case of CCHF in Tehran province during this year, who first misdiagnosed as COVID-19 infection.

Risk Factors Associated With Poor Prognosis in Children With Crimean-Congo Hemorrhagic Fever

2014 ◽  
Vol 1 (3) ◽  
Author(s):  
Seyed Mohammad Hashemi-Shahri ◽  
Batool Sharifi-Mood ◽  
Maliheh Metanat
Keyword(s):  
Risk Factors ◽  
Poor Prognosis ◽  
Hemorrhagic Fever ◽  
Crimean Congo Hemorrhagic Fever ◽  
Factors Associated

scholarly journals Crimean-Congo hemorrhagic fever: Risk factors and control measures for the infection abatement

2015 ◽  
Vol 4 (1) ◽  
pp. 15-20 ◽  
Author(s):  
SAADIA ASLAM ◽  
MUHAMMAD SHAHZAD LATIF ◽  
MUHAMMAD DAUD ◽  
ZIA UR RAHMAN ◽  
BUSHRA TABASSUM ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hemorrhagic Fever ◽  
Control Measures ◽  
Crimean Congo Hemorrhagic Fever ◽  
And Control
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