scholarly journals Correlation between secondary thrombosis in epileptic patients and serum levels of folate and vitamin B12

2016 ◽  
Vol 5 (4) ◽  
pp. 417-420 ◽  
Author(s):  
Hao Zhou ◽  
Hong-Li Huang ◽  
Nuan Wang ◽  
Xiao-Hu Pang
Keyword(s):  
Vitamin B12 ◽  
Serum Levels ◽  
Epileptic Patients ◽  
Folate And Vitamin B12

scholarly journals Oxcarbazepine administration and the serum levels of homocysteine, vitamin B12 and folate in epileptic patients: A systematic review and meta-analysis

Seizure ◽  
2017 ◽  
Vol 45 ◽  
pp. 87-94 ◽  
Author(s):  
Shahabeddin Rezaei ◽  
Sakineh Shab-Bidar ◽  
Ahmed Abdulahi Abdurahman ◽  
Kurosh Djafarian
Keyword(s):  
Systematic Review ◽  
Vitamin B12 ◽  
Meta Analysis ◽  
Serum Levels ◽  
Epileptic Patients

scholarly journals Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism

2013 ◽  
Vol 51 (3) ◽  
Author(s):  
Alexander Semmler ◽  
Susanna Moskau-Hartmann ◽  
Birgit Stoffel-Wagner ◽  
Christian Elger ◽  
Michael Linnebank
Keyword(s):  
Vitamin B12 ◽  
Antiepileptic Drugs ◽  
Genetic Variants ◽  
Plasma Levels ◽  
Serum Levels ◽  
Folate And Vitamin B12

scholarly journals Dietary Intake and Serum Levels Status of Folate and Vitamin B12 among Jordanian Colorectal Cancer Patients: a case‐control study

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Mostafa I Waly ◽  
Mostafa A Arafa ◽  
Sahar B Jriesat ◽  
Ahmed M AlKhafajei ◽  
Sunny A Sallam
Keyword(s):  
Colorectal Cancer ◽  
Dietary Intake ◽  
Vitamin B12 ◽  
Cancer Patients ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Folate And Vitamin B12 ◽  
Colorectal Cancer Patients ◽  
Control Study

scholarly journals Effects of antiepileptic drugs on the serum folate and vitamin B12 in various epileptic patients

2016 ◽  
Vol 5 (4) ◽  
pp. 413-416 ◽  
Author(s):  
Hong-Li Huang ◽  
Hao Zhou ◽  
Nuan Wang ◽  
Chun-Yu Yu
Keyword(s):  
Vitamin B12 ◽  
Antiepileptic Drugs ◽  
Serum Folate ◽  
Epileptic Patients ◽  
Folate And Vitamin B12

Association Between Homocysteine and Vitamin Levels in Demented Patients

2021 ◽  
pp. 1-12
Author(s):  
Jessica Hoffmann ◽  
Stefan Busse ◽  
Franz von Hoff ◽  
Katrin Borucki ◽  
Thomas Frodl ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Vitamin B6 ◽  
Homocysteine Level ◽  
Vitamin B1 ◽  
Lewy Body Dementia ◽  
Serum Levels ◽  
Elderly Persons ◽  
Total Homocysteine ◽  
Folate And Vitamin B12 ◽  
Elderly Control

Background: Although it is known that the nutritional status among elderly persons and, in particular, patients with dementia, is compromised, malnutrition that results in insufficient uptake of several vitamins is often not diagnosed. Objective: An elevated homocysteine level is a known strong risk factor for vascular dementia (VaD) and Alzheimer’s disease (AD). Several B vitamins are involved in the metabolism of homocysteine. Therefore, we investigated the serum levels of vitamin B1, vitamin B6, folate, and vitamin B12 in 97 patients with mild cognitive impairment (MCI) or different forms of dementia and 54 elderly control persons without dementia. Results: Compared to aged non-demented people, vitamins B1, B6, B12, and folate were decreased in serum of patients with AD, and patients with Lewy body dementia had reduced vitamin B12 level. Vitamin B6 was diminished in VaD. Patients with frontotemporal dementia showed no alterations in vitamin levels. Age was identified as an important factor contributing to the concentrations of vitamin B1 and B6 in serum, but not vitamin B12 and folate. Increased levels of total homocysteine were detected especially in MCI and AD. Homocysteine correlated negatively with levels of vitamins B6, B12, and folate and positively with Q Albumin. Conclusion: Our data suggest that despite increased homocysteine already present in MCI, vitamin levels are decreased only in dementia. We propose to determine the vitamin levels in patients with cognitive decline, but also elderly people in general, and recommend supplementing these nutrients if needed.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

scholarly journals Evaluation of Homocysteine, Folic Acid and Vitamin B12 Levels among Egyptian Children with Idiopathic Epilepsy

2014 ◽  
Vol 2 (1) ◽  
pp. 109-113
Author(s):  
Soha M. Abd El Dayem ◽  
Osama N. Saleh ◽  
Nahed A. Emara ◽  
Manal E. Kandil ◽  
Rania H. Shatla ◽  
...  
Keyword(s):  
Folic Acid ◽  
Drug Treatment ◽  
Vitamin B12 ◽  
Serum Levels ◽  
Idiopathic Epilepsy ◽  
Anti Epileptic Drug ◽  
Egyptian Children ◽  
Epileptic Patients ◽  
Epileptic Children ◽  
Generalized Epilepsy

Objective: To evaluate relationship between homocysteine (Hcy), folic acid and vitamin B12 with anti-epileptic drugs in epileptic patients and their role in epilepsy control.Patient and Methods: The study included 60 patients with idiopathic epilepsy and thirty non-epileptic children of the same age and sex served as controls. All cases were subjected to physical and neurological examination and electroencephalogram (EEG). Serum level of folic acid, homocysteine (Hcy) and vitamin B12 were done for both epileptic patients and controls. Non parametric test, one way ANOVA and Pearson’s correlation were used for analysis of data.Result: 44 patients (73.3%) had generalized epilepsy and the remaining patients had partial epilepsy (simple or complex). 37 patients (61.6%) were in grade I, 3 patients (5 %) were in grade II and the remaining 20 patients (33.3 %) were in grade III epilepsy. Vitamin B12 was significantly higher in epileptic patients. Duration of anti-epileptic drug treatment was correlated significantly to folic acid and Hcy level.Conclusion: antiepileptic drugs might upset the homeostatic balance of Hcy and its cofactors and cause abnormalities of their serum levels. The duration of anti-epileptic drug treatment was related to decrease of folic acid and increase in homocysteine levels.

scholarly journals The Relationship between Dietary Patterns and Depression is mediated by Serum Level of Folate and Vitamin B12: A Case-Control Study

2019 ◽  
Author(s):  
Maryam Khosravi ◽  
Gity Sotoudeh ◽  
Maryam Amini ◽  
Firoozeh Raisi ◽  
Anahita Mansoori ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Serum Folate ◽  
Folate And Vitamin B12 ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract Introduction Major depressive disorder is among main worldwide causes of disability. The low medication compliance rates in depressed patients as well as the high recurrence rate of the disease can bring up the nutrition-related factors as a potential preventive or treatment agent for depression. The aim of this study was to investigate the association between dietary patterns and depression via the intermediary role of the serum folate and vitamin B12, total homocysteine, tryptophan, and tryptophan/competing amino acids ratio. Methods This was an individually matched case-control study in which 110 patients with depression and 220 healthy individuals, who completed a semi-quantitative food frequency questionnaire were recruited. In addition, to measure the serum biomarkers 43 patients with depression and 43 healthy people were randomly selected from the study population. To diagnose depression the criteria of Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were utilized. Results The findings suggest that the healthy dietary pattern was significantly associated with a reduced odds of depression (OR: 0.75; 95% CI: 0.61-0.93) whereas the unhealthy dietary pattern increased it (OR: 1.382, CI: 1.116–1.71). The mediation analysis showed that the healthy dietary pattern was associated with a reduced risk of depression via increased serum levels of the folate and vitamin B12; however, the unhealthy dietary pattern was associated with increased risk of depression via decreased serum levels of folate and vitamin B12, based on tree adjusted logistic regression models. Conclusion Dietary patterns may be associated with depression by changing the serum levels of folate and vitamin B12. Further studies are required to confirm the mechanism.

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