scholarly journals Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase

2017 ◽  
Author(s):  
Jian Lu ◽  
Yongbing Qian ◽  
Wei Jin ◽  
Rui Tian ◽  
Yong Zhu ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Epithelial To Mesenchymal Transition ◽  
Lysyl Oxidase ◽  
Hypoxia Inducible Factor ◽  
Mesenchymal Transition ◽  
Hypoxia Inducible Factor 1Α

scholarly journals Lysyl oxidase promotes epithelial-to-mesenchymal transition during paraquat-induced pulmonary fibrosis

2016 ◽  
Vol 12 (2) ◽  
pp. 499-507 ◽  
Author(s):  
Jinfeng Wang ◽  
Yong Zhu ◽  
Jiuting Tan ◽  
Xiaoxiao Meng ◽  
Hui Xie ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Epithelial To Mesenchymal Transition ◽  
Amine Oxidase ◽  
Lysyl Oxidase ◽  
Critical Role ◽  
Mesenchymal Transition

Lysyl oxidase (LOX) is a copper-dependent amine oxidase that plays a critical role in pulmonary fibrosis.

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